Dema018530.1
Basic Information
- Insect
- Drosophila emarginata
- Gene Symbol
- -
- Assembly
- GCA_037075365.1
- Location
- JBAMCD010000296.1:2565549-2567855[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.12 10 7.2 9.0 3 23 253 273 251 273 0.96 2 12 0.0018 0.16 12.9 0.5 1 23 279 304 279 304 0.95 3 12 1.7e-05 0.0015 19.2 0.4 1 23 311 336 311 336 0.94 4 12 0.00087 0.076 13.9 3.5 1 23 345 367 345 367 0.97 5 12 1.1e-05 0.00098 19.8 0.1 1 23 374 396 374 396 0.97 6 12 0.013 1.1 10.2 0.4 1 23 402 424 402 424 0.97 7 12 0.0014 0.12 13.2 0.8 1 23 430 453 430 453 0.97 8 12 0.0078 0.69 10.9 2.8 1 23 459 481 459 481 0.96 9 12 1.2e-05 0.001 19.7 0.8 2 23 488 509 487 509 0.97 10 12 4.3e-05 0.0038 18.0 1.0 1 23 577 600 577 600 0.96 11 12 0.031 2.7 9.0 6.5 1 23 606 628 606 628 0.94 12 12 0.0016 0.14 13.0 3.2 1 23 634 656 634 656 0.98
Sequence Information
- Coding Sequence
- ATGAATCCGAGCCAAGGTGAATACTCCATACACACCGTCTGCCGTACATGCCTTACCACATTAGAGAATGTCATGGCCTACGATTTGTTTCTCATACCAGGATTGGCCAAGAAGCTATGTATATGCACTTCGCTGTCAGTTGATCAGCAGGATGGGTTTCCCAAGAATCTGTGTGCCAATTGCTTTACCAAGCTAAACGATTTAAATGAGTTCCAGAAAATGTGTGTCGATTcagttcaaaaatttcaagatATGCTGACTACCCAGGCATTTGGTAACGGTGGTCCAGAGCCGGATACACCTGAAGATGAGGAGGAGGATAGAAATTTTGATCCCTTGTTAAATTCAAAAGTAGAAACTATGGACAACGAGGAGGAGGTTATGAAACTGCTGGAGAATGTGGATAAAGAGGCGGGAAACGAGTtagaggaggaggaagaggacCAATATGAAGATGAGGAAGAAAATGATTATGACTTCAATGTGGGGAGTAgcaatgatgataatgaaatTGATTACGAATTAAATAGCAGCGATGACGATATACCTCTAGCACAAAGATCAACGCGTGCCCAAAAGAATGTCAAAGTGGAGCGAAAGGCAAAGGGTAAAGAGCATTTTAAAAGGGAACAAGCGGAGGAAGAGGCGGAGGATACATCATCAACTGAAATTGAGTCACATGTTGGTTCTGCGAAAGCCAAATCAAAACGCAAGAGGATTCCACCCGATGAGCGTCACTTAAATCGTCTAATCGATTGCCACATTTGCCATCAGAAATTCAAGAAAGCCTCGTGCTACGATGAGCATATGAAGCATCATAACGATCTCTTACCTTACCAATGTACAGTGGATTCCTGCCGCAAGGGTTTCACCACAGCCAATGGGCTTAAGGTACACATAGAGCATGCCCATACAGACGAATCTAAAATGCATCCATGCTCCGTCGAGGGCTGCAACAGAAGTTTTGCTCGCCCTTCGCTACTCAATGTCCACCTTAAGCGAACccataaattgcaattaccACCACGAGAATTTCCTTGTACGGAGTGCGAAAAGATATTCCGCTGTCAGACAGCTCTGAAAAAGCACATGTATAAGCATACGGGAAGGGAATTGCCATTTGCCTGTGAAATATGCGGGAAACGTTTTCCCATTAATAGTGCTTTAAGGGATCATCTGTTACGCCATGCCGGCATCAAAAATCACGTATGTCCATATTGTGGTGTTGGCAAAACCACCCGGCAGGAGTGGAACAATCACATTCTAACTCATACCAAAGAGAAGAAATTCCAATGCGAACTCTGCAATCATGCATCCACCAATAAGCAAGCTCTTAGCAATCATGTCAAGGTGGTCCATGAGAAACGCAAAGATTTCGCGTGCCAATATTGTGGTAAAACCTTTGGCAAATCCTTTGCCTGTAAAGTCCACGAGCGTAGTCACACGGGAGAGAAGAACAGTGAATGTAAAATATGTGGCAAGATCTTTTTGCAGGAATCGAGTCTTACCAAGCATTTAAAAACCCACGAGAAACGGGAATTGCCGAAAGTGGGCAACGATAATGTCGTATCTCCCCAACTTGATCCGAATAAGAAAACCTACAATTCGGCCCGCGTTGAACGTGTGGACATATCCCAATTGGCTGGTACAGCGGTTAATCCCATTACCTCAGTTTCTGTACCTTCGTGGTCTCTGCAAAGCGATTCCTTTAGCAAAAAGGAAGGCCAACATATTTGTCCTGATTGCGGCAAGGGTTTCAATCACATTGGCAATATGAAACTTCACTATAAAGTTGTTCACCTAAAAGTCAAAGATTTTTGCTGTCGCTTCTGTCCCAAGCGTTTTGCCAAAAAACATTATCTACGCGAACACGAATACATTCACACTGGTGAAAAGCCCTATGAATGCAAGATCTGTGGCAATCATTTCCGTCAAGATCATGTGATGAAGGTCCATATGAAAATCCACGACAAGCCACCGAAACCACCCAAGCCACCGGCCAAACCAAAGAAATTACCCAAATCAGAGAATCCACCAAATAAACGCCAACCACCGTTTAAGCAGTATCAGGATCCAGCTGCCGAGCGAGCCGCTGCCACAGCCGAGCTGTTGGCCTATCAAATAGAAGAGAATGAAGCAAAGCGCAAGGCGGAAATGGAGTTACGAAAGATTCAAGAAGCAGCTGTGGAGCAGCTAAGCAAGTTGGAGATGCTCCAGGCACCAGCCAATACCTATGATAGTTTGTATGCTCAAAAGGCGGCCGAGGATCAAACTATAGTGGATTCTCTGAAACAGGATAAtgtgtaa
- Protein Sequence
- MNPSQGEYSIHTVCRTCLTTLENVMAYDLFLIPGLAKKLCICTSLSVDQQDGFPKNLCANCFTKLNDLNEFQKMCVDSVQKFQDMLTTQAFGNGGPEPDTPEDEEEDRNFDPLLNSKVETMDNEEEVMKLLENVDKEAGNELEEEEEDQYEDEEENDYDFNVGSSNDDNEIDYELNSSDDDIPLAQRSTRAQKNVKVERKAKGKEHFKREQAEEEAEDTSSTEIESHVGSAKAKSKRKRIPPDERHLNRLIDCHICHQKFKKASCYDEHMKHHNDLLPYQCTVDSCRKGFTTANGLKVHIEHAHTDESKMHPCSVEGCNRSFARPSLLNVHLKRTHKLQLPPREFPCTECEKIFRCQTALKKHMYKHTGRELPFACEICGKRFPINSALRDHLLRHAGIKNHVCPYCGVGKTTRQEWNNHILTHTKEKKFQCELCNHASTNKQALSNHVKVVHEKRKDFACQYCGKTFGKSFACKVHERSHTGEKNSECKICGKIFLQESSLTKHLKTHEKRELPKVGNDNVVSPQLDPNKKTYNSARVERVDISQLAGTAVNPITSVSVPSWSLQSDSFSKKEGQHICPDCGKGFNHIGNMKLHYKVVHLKVKDFCCRFCPKRFAKKHYLREHEYIHTGEKPYECKICGNHFRQDHVMKVHMKIHDKPPKPPKPPAKPKKLPKSENPPNKRQPPFKQYQDPAAERAAATAELLAYQIEENEAKRKAEMELRKIQEAAVEQLSKLEMLQAPANTYDSLYAQKAAEDQTIVDSLKQDNV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00556013;
- 90% Identity
- iTF_00577953;
- 80% Identity
- -