Basic Information

Insect: Drosophila emarginata
Gene Symbol: -
Assembly: GCA_037075365.1
Location: JBAMCD010000221.1:23434456-23436567[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.3 26 5.9 0.4 1 21 315 335 315 336 0.95

2 10 1.2e-06 0.00011 22.8 2.4 1 23 344 366 344 366 0.99

3 10 0.0046 0.4 11.6 0.6 1 23 369 392 369 392 0.93

4 10 2e-06 0.00018 22.2 0.8 2 23 399 420 398 420 0.98

5 10 3.6e-08 3.1e-06 27.7 1.0 1 23 426 448 426 448 0.98

6 10 1.8e-06 0.00016 22.3 1.0 1 23 454 476 454 476 0.99

7 10 0.00081 0.071 14.0 3.0 1 23 482 504 482 504 0.98

8 10 0.00071 0.062 14.2 0.4 1 23 510 532 510 532 0.98

9 10 0.00051 0.045 14.6 3.5 1 23 538 560 538 560 0.98

10 10 5.4e-05 0.0047 17.7 0.9 1 23 566 588 566 588 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.3	26	5.9	0.4	1	21	315	335	315	336	0.95
2	10	1.2e-06	0.00011	22.8	2.4	1	23	344	366	344	366	0.99
3	10	0.0046	0.4	11.6	0.6	1	23	369	392	369	392	0.93
4	10	2e-06	0.00018	22.2	0.8	2	23	399	420	398	420	0.98
5	10	3.6e-08	3.1e-06	27.7	1.0	1	23	426	448	426	448	0.98
6	10	1.8e-06	0.00016	22.3	1.0	1	23	454	476	454	476	0.99
7	10	0.00081	0.071	14.0	3.0	1	23	482	504	482	504	0.98
8	10	0.00071	0.062	14.2	0.4	1	23	510	532	510	532	0.98
9	10	0.00051	0.045	14.6	3.5	1	23	538	560	538	560	0.98
10	10	5.4e-05	0.0047	17.7	0.9	1	23	566	588	566	588	0.97

Sequence Information

Coding Sequence: atggatattGAGAAGATTTGTCTGACTTGTTTGAGCTTGTCGGGtccttttctttcaatttacgATGGAGGCTCTGGTACCGGAAACTGCTTAGCTGATATGCTAAGTGACTTTACCAAGACAAAGCCCCAACGTCAAAACAATTTGCCCGAAAAGGTTTGCTTAAATTGCCTGAGTGAGATTAATCACTGCTActcatttaaaatcaaatgcgAAAACTCAAGTAGAACGTTACGGCAACTGCTGCCAAATGCCTTGCCAGAGGAGCAGGATCAGGCGCCTCCAAAGCCTCAAGTGGTCACGAAAGATCAATGTGTTCAAGCCAGTAACAGTCCAGTGGCAATGGcatcaattgaaattcaaacaGATGAAATTTCgttattcaaatataataGTCAGGAGATTAAGATTAGCACTAGCTCAGTGATCGAAGATCAGCCTGAGGAAGATGAAGGAGATGGTCAGGCTTTTGAATATGAGTTAACTCAACAAGGTGGTGCCACCTCAGAAAAGGATGTCGTTCATATGAAATATGAAGCTGAAATGgacaaaatggcaaatgaatATAATTTCTCCATTTTCAACAATGCCAATGGGGAGACAGAGATTTCACCTGCTCCCTTGCCAGCTCCAAGTCAACTGCAGGTTACCACTCGTAAAAGTGCAGCCAAGATGCTAAGCCTGCAACGGCAAGAGGCGGAAGGGGGCCAGGAACCGAATCAGTCGCCAAAACCACAAGAAACAATAGAACCCCCGGCCCAGTTGAAGAGATCCACTAGACGTCGTCCTGCGGAAAAACCGGATGAGCAGACTGAGGTGGCTACAACAAAACGATTACGCAAATCTCTTAATACCACAACaccaggagcagcagcaacaggcgGAGCATTAACAGAAACAGGAGTTGGAGCAGTAGCAACAGTGCCTGTCGCAGAACTTAAGTATCATTGTGATCGGTGCCAGGCTGGTTTTGCCCTGGAAAAGTCCCTGAGTATACATCGGCGACAAAATGGCTGTACCAATCGCAATTTCAAATGCCAAGATTGCGATAAGGTTTTTGTTTCCCACGATCATTTGGTTGAGCATCAAGCAACCCATGGCACATATAATTGTCAAGAGTGTGGCATGCTATGCGATTCCAAAGAGCAACTGGGAAGGCACATGGTTCAGGGGCACAAGCGTAATCTGAGAAATCAATGCTCAGTTTGTCAGAAGGTATTCACCATGTTATCCACATTGCGGGATCATATGCGTATCCATACTGGCGAGAAACCGTTTGTGTGCAATATTTGTGGCAAAAGCTTCACCCAAAATGCTAATCTCCGTCAGCATAAATTACGCCACTCGGAAacgaaaagttttaaatgcGATCAATGCTCAAACTCGTTTGTAACTAAAGCAGAATTAACCTCCCACATACGTACCCATACGGGAGATAAGCCCTTTGAATGTGATGTCTGTTTGGCCAAGTTTACCACGAGCTGTTCCCTAGCAAAGCACAAACGTAAACATACCGGAGAGCGTCCATATGCCTGTGAAATGTGTCCCATGCGTTTCACTGCCTTGAATGTGCTCAAAAATCATCGTCGTACTCACACCGGAGAACGTCCTTTTGTCTGTATGTTTTGTCCCAAGAGTTTCACCCAACGCGGCGACTGTCAAATGCATCAACGGACCCATGAGGgcgctaaaatatatatttgttccGTTTGCAATGAAAGTTTCAAAACTATGCCCGAATATCGCAAACATATGACCAATCATGGCCAGCAACAGGATGAGGCGCAGCCAGGCAAGCGTTCGGTGCATCATTTCACATTGTTCAGCAATAAGGAAAACGGAAATGCTGGTCTGGAGGATGTTACAGATGAAGAGGCAGACGACAatgatgaggaggaggaagtTGAGGAAGACACAGCATTGGTGCtctaa
Protein Sequence: MDIEKICLTCLSLSGPFLSIYDGGSGTGNCLADMLSDFTKTKPQRQNNLPEKVCLNCLSEINHCYSFKIKCENSSRTLRQLLPNALPEEQDQAPPKPQVVTKDQCVQASNSPVAMASIEIQTDEISLFKYNSQEIKISTSSVIEDQPEEDEGDGQAFEYELTQQGGATSEKDVVHMKYEAEMDKMANEYNFSIFNNANGETEISPAPLPAPSQLQVTTRKSAAKMLSLQRQEAEGGQEPNQSPKPQETIEPPAQLKRSTRRRPAEKPDEQTEVATTKRLRKSLNTTTPGAAATGGALTETGVGAVATVPVAELKYHCDRCQAGFALEKSLSIHRRQNGCTNRNFKCQDCDKVFVSHDHLVEHQATHGTYNCQECGMLCDSKEQLGRHMVQGHKRNLRNQCSVCQKVFTMLSTLRDHMRIHTGEKPFVCNICGKSFTQNANLRQHKLRHSETKSFKCDQCSNSFVTKAELTSHIRTHTGDKPFECDVCLAKFTTSCSLAKHKRKHTGERPYACEMCPMRFTALNVLKNHRRTHTGERPFVCMFCPKSFTQRGDCQMHQRTHEGAKIYICSVCNESFKTMPEYRKHMTNHGQQQDEAQPGKRSVHHFTLFSNKENGNAGLEDVTDEEADDNDEEEEVEEDTALVL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00555998;
90% Identity: -
80% Identity: -