Basic Information

Insect: Drosophila emarginata
Gene Symbol: su(Hw)
Assembly: GCA_037075365.1
Location: JBAMCD010000221.1:25670000-25673276[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.00066 0.058 14.3 2.2 1 20 229 248 229 250 0.94

2 12 2.7e-06 0.00024 21.7 0.4 3 23 301 322 299 322 0.93

3 12 1.1 97 4.1 0.1 1 23 328 350 328 350 0.88

4 12 5.4e-07 4.7e-05 24.0 2.4 1 21 357 377 357 378 0.95

5 12 6.1e-06 0.00053 20.7 1.0 2 23 390 411 389 411 0.96

6 12 0.0001 0.009 16.8 5.3 1 23 422 444 422 444 0.99

7 12 8e-05 0.007 17.1 0.9 1 23 450 472 450 472 0.97

8 12 9.3e-06 0.00081 20.1 0.7 1 23 478 500 478 500 0.98

9 12 2e-06 0.00018 22.2 2.2 1 23 506 528 506 528 0.97

10 12 2.3e-05 0.002 18.9 0.5 1 23 532 554 532 554 0.96

11 12 4.1e-05 0.0036 18.1 0.2 1 21 562 582 562 586 0.92

12 12 1.2e-05 0.001 19.7 0.4 3 23 606 627 604 627 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.00066	0.058	14.3	2.2	1	20	229	248	229	250	0.94
2	12	2.7e-06	0.00024	21.7	0.4	3	23	301	322	299	322	0.93
3	12	1.1	97	4.1	0.1	1	23	328	350	328	350	0.88
4	12	5.4e-07	4.7e-05	24.0	2.4	1	21	357	377	357	378	0.95
5	12	6.1e-06	0.00053	20.7	1.0	2	23	390	411	389	411	0.96
6	12	0.0001	0.009	16.8	5.3	1	23	422	444	422	444	0.99
7	12	8e-05	0.007	17.1	0.9	1	23	450	472	450	472	0.97
8	12	9.3e-06	0.00081	20.1	0.7	1	23	478	500	478	500	0.98
9	12	2e-06	0.00018	22.2	2.2	1	23	506	528	506	528	0.97
10	12	2.3e-05	0.002	18.9	0.5	1	23	532	554	532	554	0.96
11	12	4.1e-05	0.0036	18.1	0.2	1	21	562	582	562	586	0.92
12	12	1.2e-05	0.001	19.7	0.4	3	23	606	627	604	627	0.97

Sequence Information

Coding Sequence: ATGAGTGCCTCCAAGGAGGGCAAAAGGGCGGAGAAGGAGACTGTTGTGAAAATCGTGGACATTGATCAAGCGTCGACGCCCAAGGAGAGCAGCACTCGACCAGTAACCCGTATGAAATTGCTGAACGATGTGACTGGATCGGGGACTCTAACCAGTGTCAAGCCGGAAAAACGTGGAGGTGCTCGGATTAAAATACTCAACGATGATCCCATCACGCCGCAAAGAACGGAGAAACGAACAAGCTGTGGTAAAAAGACAGTTAGTCCTCCCTCTGCCCCCACTGCATCGACTGTAAAGATTCTCAACGATAAGCGTTTCTCTTCGCCACTTTCTTCTATGGAAACGGTAAAGATTAAGGCAACTGCtagtaagaaaaagaaaatggatcATTATGTCCTTGAATCAGTTAAAAATGAGAACAGCAAAGTTGCCCCGGATGTTACTGCCAAAGTAGTTGTCCAggacgacgatgatgaagatgatgatgacggaGCCATTGCCTACATCCTTGccgatgacgacgatgatgatgaggtaACCATTCCTAACAATGACAAGCAAATTGTAGTCGCTGGCgtagatgaagatgatgacgGTGAGGATGATGACGAAGTGGACGATACCCAAATCACTGGTGGTCGTAATACAACGGCCAATCAGAGCAGCATTAAAGAAATTGTGGAACATGTCTGCGGCAAATGCTATAAGACATTCCGTCGCGTCAAGAGTTTAAAGAAACATTTGGAATTCTGTCGATATGACAGTGGCTATCATCTACGCAAGGCGGACATGTTAAGGAATCTGGAGAAAATCGAAAAAGATGCTGTGGTCATGGAGAAGAAGGACATCTGCTTCTGTTGCAACGAAAGCTACGATACTTTCCACTTGGGTCACATCAACTGTCCCGATTGTCCAAAGTCCTTTAAGACGCAAACCAGCTACGAGCGTCACATTTTTATCACTCATTCGGAATTCAATACGTATCCCTGTTCCATTTGCAATGCAAACTTGCGCAGTGCCGCATTACAAAAGCTTCACGAGGAGCAGCACAAGAATCGTGGCAAACCGTATGCCTGTAAAATCTGTGGCAAGGACTTTACAAGGTCCTATCATCTAAAACGTCATCAAAAATACTCTTCATGCTCGGCCAACGAGACTGATACCATGAGCTGTAAGGTGTGTGATCGAGTCTTCTATCGCCTAGACAATCTACGTTCCCATCTAAAGCAACATCTGGGCACACAAGTGGTTAAGAAGCCAGAATACATGTGTCATGTGTGCAAGAATTGCTTCTACAGTTTATCCACGCTCAACATTCACATACGCACCCATACGGGTGAGAAACCCTTCGATTGTGATTTGTGCGATAAGAAATTTTCTGCTTTGGTGGCTCTTAAGAAGCATCGACGCTATCATACAGGCGAGAAACCCTACAGCTGTACAGTGtGCAATCAATCTTTTGCCGTTAAGGAAGTCCTTAATCGTCACATGAAACGTCACACGGGTGAACGTCCTCACAAGTGTAACGAGTGCGGTAAAAGTTTCATTCAGGCTACTCAATTGCGTACCCATTCCAAGGTTCATTTGCGTCCATACGCCTGTGATTTGTGTGATGAAAAGTTTAAAACGGAGAAGCAattggAACGCCATGTTAAGGATCACTCACGGCAGAGGCGAGCAGCTTTCTCCTGCTCTGAATGTAAACGAAACTTTCGTAATGCTGATTTGCTCAAAGAGCATATGGACGCTGGCGATCATACACCCAAGCCTCAACGCGCAAAGCGCTCGAACACCAAAATTACTGGACGCACTGATTGCGCCATTTGTGACAAGAACTTTGATAGCACTGAAACCCTGAGGAAGCACATACGCACTGTTCACGAGTGTGATCCCGATGATATATTTGGTGTTGATCCACCGTCTGCGAAACGTAACAAGGCTGGTGACAAATCTACCAATCTGGTGGTTGATGAGGAATCGGGATTAGCTCAAAACACTGCGGCCGGTTCGCTTATTTCCAGTCAAACCGATGGCAACGGTGTGGTGGTTCGTGAGTTTCTTGTGGATGAGGGTGATGGCACTGCCCAGACAATTATGCTCGAGAACGAGACCTATACCATATTGCCACTCGAAGGAGATATTGATGGTGGTGGCGAACCATTACCAACGggtaaaaaatcaaagaaaaaacaacttcAGATTTCGCCTGTTGTTAAGAAGGAGCAACGCAAATCATTGGCTGCCAGTTTGGCtgaggccattgccgataatGTAGATGAAGAGGACTTTACCGGCGAAGTGCTTACCGAAGAGGATGTGAAGCTTAAACAAAATGTGGCCAAATTGATTGATATGCTGGTGGATCCACCCATTCTAAAGAAATATGGCTGGCCCAACACCTCTGAGGAGACGGTTCTCTGCAAGGTGATTGAGAATTGTGGCCACGATTTGACCAAAAGTGGCGATAACTATGCGGAAATGGAATATGGGACACGTATGCGTGAATATTGCAAATTGCTATTCACTGTGGTGATACACAATGATTCTATCAAATCCTTGCTCAATAATTTTCCCATTGACGATGTAATTGAATACGTACTGGGTGACGAGGATCAGGATGATAGCGAAAGCAAAGACAAAGACCATGACGCTGTTGATGGTATTGattatgataatgatgatgacaataacgatgatgaagatgatgatgatgataaaaagACGAAAATCATCAATAAGAAAGAatag
Protein Sequence: MSASKEGKRAEKETVVKIVDIDQASTPKESSTRPVTRMKLLNDVTGSGTLTSVKPEKRGGARIKILNDDPITPQRTEKRTSCGKKTVSPPSAPTASTVKILNDKRFSSPLSSMETVKIKATASKKKKMDHYVLESVKNENSKVAPDVTAKVVVQDDDDEDDDDGAIAYILADDDDDDEVTIPNNDKQIVVAGVDEDDDGEDDDEVDDTQITGGRNTTANQSSIKEIVEHVCGKCYKTFRRVKSLKKHLEFCRYDSGYHLRKADMLRNLEKIEKDAVVMEKKDICFCCNESYDTFHLGHINCPDCPKSFKTQTSYERHIFITHSEFNTYPCSICNANLRSAALQKLHEEQHKNRGKPYACKICGKDFTRSYHLKRHQKYSSCSANETDTMSCKVCDRVFYRLDNLRSHLKQHLGTQVVKKPEYMCHVCKNCFYSLSTLNIHIRTHTGEKPFDCDLCDKKFSALVALKKHRRYHTGEKPYSCTVCNQSFAVKEVLNRHMKRHTGERPHKCNECGKSFIQATQLRTHSKVHLRPYACDLCDEKFKTEKQLERHVKDHSRQRRAAFSCSECKRNFRNADLLKEHMDAGDHTPKPQRAKRSNTKITGRTDCAICDKNFDSTETLRKHIRTVHECDPDDIFGVDPPSAKRNKAGDKSTNLVVDEESGLAQNTAAGSLISSQTDGNGVVVREFLVDEGDGTAQTIMLENETYTILPLEGDIDGGGEPLPTGKKSKKKQLQISPVVKKEQRKSLAASLAEAIADNVDEEDFTGEVLTEEDVKLKQNVAKLIDMLVDPPILKKYGWPNTSEETVLCKVIENCGHDLTKSGDNYAEMEYGTRMREYCKLLFTVVIHNDSIKSLLNNFPIDDVIEYVLGDEDQDDSESKDKDHDAVDGIDYDNDDDNNDDEDDDDDKKTKIINKKE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00600464;
90% Identity: iTF_00600464;
80% Identity: -