Dema011938.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila emarginata
Gene Symbol
kipf
Assembly
GCA_037075365.1
Location
JBAMCD010000221.1:15754984-15757964[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 14 0.005 0.44 11.5 4.2 1 21 165 185 165 188 0.95
2 14 1.4e-06 0.00013 22.6 1.6 1 23 194 216 194 216 0.99
3 14 4e-06 0.00035 21.2 1.3 1 23 222 244 222 244 0.99
4 14 1.4e-05 0.0012 19.5 2.3 1 23 353 375 353 375 0.99
5 14 0.0037 0.32 11.9 0.4 1 23 380 405 380 405 0.97
6 14 2.1e-06 0.00018 22.1 2.2 1 23 411 433 411 433 0.99
7 14 1.5e-05 0.0013 19.5 3.7 1 23 439 462 439 462 0.97
8 14 1.1e-05 0.00095 19.9 2.7 2 23 519 540 518 540 0.94
9 14 4.9e-06 0.00043 21.0 3.5 1 21 543 563 543 565 0.95
10 14 0.0024 0.21 12.5 1.5 1 23 601 624 601 624 0.97
11 14 7e-07 6.2e-05 23.6 3.4 1 23 670 692 670 692 0.98
12 14 0.0002 0.017 15.9 1.2 2 23 697 718 696 718 0.96
13 14 0.00011 0.0099 16.7 5.7 1 23 723 745 723 745 0.98
14 14 0.00024 0.021 15.6 3.4 1 23 779 802 779 802 0.95

Sequence Information

Coding Sequence
ATGGACAATGTGTGTCGCGTTTGTAGGGATGGCTCGGTCACCCTAGTAGAAATATTTACCGGAGTGGAGAACGGTGACGACGTCGAGGACCAAGAAAAGAATTTAGCTTATGTCCTTAGCCAGTGTGCCAACTGTCAGGTTACACGGGACGATTTACTACCAAAACAAATATGCTTATCCTGTGTCCTAGCAGCTCAAAATGCTTTCCGATTCAAGAAAACATGCGAGCAGAGCTATCAACATTTTTGTCAACTTCTGGAGATAGGAAGGGAAAATCAGCGTAGGGACCCGCCGGTAGGGCGGCGttttaatgataatgatgtgcTTATGGAGGGTGGCCTTCATGTCATcgatgtgagctgcattaaaATAGAGCCTTTTGTCGAGCTCCAAGAAAATGACATGCCAATTAGCAACGTTACTATGGAGGATACATCTGTTACCATTCCTTCCAGTGAAGATCTGGACAACCGaaataacgAGTTGTTTCCCCATGTGTGCCAGTACTGCACTAAAGGTTTTCGAGGAACCTATGAGCTCAATAATCACATTCGTTGTCGTCATACAGGAGAACGGCCTTTTAAATGCCCCCATTGCCCAAAGGAATTCTCTGTACGAATCTATTTAAGGAATCATCTGCGCGTCCACACGGGAGAGCGTCCTTATAAATGCCCACATTGCCCTAACGCTTTCACCCTGTCCAACAGCCTGAAAGCTCACATTCGAAAACATGGTGATGGCCGGAATCGTCTCTGTTCCCGTAAGCTGTTTAGATGCGACTGTTGTGCAGCGTCTTTTCGGGAGCACTTTGGCCTGCGCATGCACAAGCAATTAAAGCATCGCATCAACGATACAATCGCGAAAACTATTGGgaAAGCTAATGAAAAGCGCTCTCAGTCGTCGATACAACGTTCCAAGACAAACgctaaattacaaaatttgggATTTCAGGAAGGTCTTGTGGAAATTAAGAAAGAACCGGTTGAAGATGGTATGGATACTCCTGCCGCAGCTGTCACCGACCAACCAAATCAGCAAGTTGATGATCCTAATAGATATCGCTGTGAAATTTGTGACATGACGTTTCAATACAGATACGCATTTACTAATCATATGCGCTATCATATGAAGCGACCCTTTCGGTGTCCTGATCCAAATTGTTCATTGGCCTTTCAAACGGAACTAAATCTCAGACAGCATCAGATGCGTTTTCATGCTTCCGATTGGCCATTTCAATGCAGAGAATGTCCCAAGGGTTTCTACactaattacaaattaaaactgCACATGCGATCCCACACTGGAGAACGTCCATTTGAATGTCCACATTGTCTACAAAGATTTACCCAAAAGCAGAATTTAAATCGCCATATAACAAGAAGACATTCACAGGCAGATCCTATAGAAACAACTTCAACGAATGGGCAAACTAGTGATAAACACAAGAAGACCAGTCCAGATCCATACCTAGTGATTAAAACGGAATTTCCAGAGCCGACTGGACTCCATGAATGTCTTGAAGAGGAAATTTTACCAGATCAAGGCAACAGAGACATGTGCCACATATGCGGAAAACATTTTTCGGATACATCCACTCTAAATCGTCATGTTAGTGGTCATACAGGCTTTCAGTGTCCACACTGTCCAAAGTCTTACAcccaaaacaataatttaaaggCTCACATTCTCTGTCACCATGAACAATTGAGTGATGCAAAGAAGCCAGCAAATTCTGGAGCAAAGCAAAAGTTAAAGCAgggaaaattaataaagtccAAGACATCTAAAGGAAAGATCAGTTATCGTTGCAAATGGTGTCCAATTGCTTTCCGAGAACAACATAAAATGGTGCTCCATATGCagcagaaacacaaaaaacgtTTAAAGCAGAGTTCCATCGAAGAAGAACTGCCGAAACCGAATAGCCCTATTGAAAATGAGATGAATAACATAGTGGTAGCGCGATCCGAAAAAGAGGTCTTGATACCAAAAGCTTCGACAAAGACTCATAAGTGTAGTGTCTGTGGAAAGGCTTTCACGAGGAGATTTAGTTTTATCCAGCACATTCGTACACATAAGCCACCCTTAAACTGCACTTTGTGCTCCAAgcagtttaatttttatgcccAGTTAAGAATTCACATGCGTCTGCACACAGGCGGAAGGTTTCAATGTGCTCACTGTTCCAACTCCTATTCTCGAAAAGATAATTTAGTTAAACATATgcacaaacataaaaatgaaacggcATTTGAAACAAGTGCAGATATTAACGATACGAATCCTGTTGAAGATGCGGTTGAAGATGAGTCTGGTGCACATACGGATACCCTTTTTAACTGTCTACTGTGTTCAAAATCATTTCGCTATAAATATAATCTAAGGCTCCATAAGCTCATGAAGCACGGCATCAACGAGAAAACAAATGATgtagaaaatcaaaatatgaaCTTGGAACAGGAtaccaatttaaaattgcGGAACAGACCTGGAGCTGGTGCGTACGAAGAGCTGGAATTCGAGGACAGTGATGTTGAAAGGCGTaacatcaataaaaaaaagacctTGTCAATTCCGAAACCAATAATTGGTGAACAAATACCATTACCACAAACACCAACAACCGAAGATCATAAGCCCAATTCAGTAGACAGTCTGACTAAATCGTAA
Protein Sequence
MDNVCRVCRDGSVTLVEIFTGVENGDDVEDQEKNLAYVLSQCANCQVTRDDLLPKQICLSCVLAAQNAFRFKKTCEQSYQHFCQLLEIGRENQRRDPPVGRRFNDNDVLMEGGLHVIDVSCIKIEPFVELQENDMPISNVTMEDTSVTIPSSEDLDNRNNELFPHVCQYCTKGFRGTYELNNHIRCRHTGERPFKCPHCPKEFSVRIYLRNHLRVHTGERPYKCPHCPNAFTLSNSLKAHIRKHGDGRNRLCSRKLFRCDCCAASFREHFGLRMHKQLKHRINDTIAKTIGKANEKRSQSSIQRSKTNAKLQNLGFQEGLVEIKKEPVEDGMDTPAAAVTDQPNQQVDDPNRYRCEICDMTFQYRYAFTNHMRYHMKRPFRCPDPNCSLAFQTELNLRQHQMRFHASDWPFQCRECPKGFYTNYKLKLHMRSHTGERPFECPHCLQRFTQKQNLNRHITRRHSQADPIETTSTNGQTSDKHKKTSPDPYLVIKTEFPEPTGLHECLEEEILPDQGNRDMCHICGKHFSDTSTLNRHVSGHTGFQCPHCPKSYTQNNNLKAHILCHHEQLSDAKKPANSGAKQKLKQGKLIKSKTSKGKISYRCKWCPIAFREQHKMVLHMQQKHKKRLKQSSIEEELPKPNSPIENEMNNIVVARSEKEVLIPKASTKTHKCSVCGKAFTRRFSFIQHIRTHKPPLNCTLCSKQFNFYAQLRIHMRLHTGGRFQCAHCSNSYSRKDNLVKHMHKHKNETAFETSADINDTNPVEDAVEDESGAHTDTLFNCLLCSKSFRYKYNLRLHKLMKHGINEKTNDVENQNMNLEQDTNLKLRNRPGAGAYEELEFEDSDVERRNINKKKTLSIPKPIIGEQIPLPQTPTTEDHKPNSVDSLTKS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
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90% Identity
-
80% Identity
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