Basic Information

Insect: Drosophila emarginata
Gene Symbol: -
Assembly: GCA_037075365.1
Location: JBAMCD010000283.1:3274754-3276372[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.00013 0.012 16.4 0.6 3 23 169 190 167 190 0.96

2 12 0.00016 0.014 16.2 4.6 3 23 200 220 196 220 0.93

3 12 1.1e-05 0.001 19.8 3.1 1 23 226 248 226 248 0.98

4 12 4.4e-05 0.0038 18.0 6.1 1 23 254 276 254 276 0.99

5 12 1.9e-06 0.00017 22.2 0.3 1 23 282 304 282 304 0.98

6 12 7.9e-07 6.9e-05 23.4 2.8 1 23 310 332 310 332 0.99

7 12 6.8e-08 6e-06 26.8 1.2 1 23 338 360 338 360 0.99

8 12 1.1e-06 9.9e-05 23.0 7.3 1 23 366 388 366 388 0.99

9 12 2e-06 0.00017 22.2 1.2 1 23 394 416 394 416 0.98

10 12 0.00031 0.027 15.3 6.2 1 23 424 446 424 446 0.99

11 12 0.00012 0.011 16.5 1.9 1 23 464 486 464 486 0.98

12 12 1.2e-06 0.00011 22.8 4.0 1 23 491 514 491 515 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.00013	0.012	16.4	0.6	3	23	169	190	167	190	0.96
2	12	0.00016	0.014	16.2	4.6	3	23	200	220	196	220	0.93
3	12	1.1e-05	0.001	19.8	3.1	1	23	226	248	226	248	0.98
4	12	4.4e-05	0.0038	18.0	6.1	1	23	254	276	254	276	0.99
5	12	1.9e-06	0.00017	22.2	0.3	1	23	282	304	282	304	0.98
6	12	7.9e-07	6.9e-05	23.4	2.8	1	23	310	332	310	332	0.99
7	12	6.8e-08	6e-06	26.8	1.2	1	23	338	360	338	360	0.99
8	12	1.1e-06	9.9e-05	23.0	7.3	1	23	366	388	366	388	0.99
9	12	2e-06	0.00017	22.2	1.2	1	23	394	416	394	416	0.98
10	12	0.00031	0.027	15.3	6.2	1	23	424	446	424	446	0.99
11	12	0.00012	0.011	16.5	1.9	1	23	464	486	464	486	0.98
12	12	1.2e-06	0.00011	22.8	4.0	1	23	491	514	491	515	0.97

Sequence Information

Coding Sequence: atgaaagaattcTGCCGAGTGTGCATGGATACATCTGTGACTTTGATCGACATCTTCTCCAAGCAACAGGCAACAGATCAGGATCCGAGTCTGCCGGATATGATGAATGACATATTGAAGGAGAACTATCAAGTCAAGCAGGATGCACTGCCTCAACATATTTGCCTTGGTTGTGTAATAGCTGCCGAAAATGCTTATCTTTTTAAACAACGATGTGAACAAAGTTTTATCCATTTTTGTCAACTGTTGAAGGAGGAAAACACATACGACTCGGTGGAGAAATATTTGACGGAACTAAACACAGATAATCATGGGTTTCAGATAGATGTTAACGAGGAATTTAACAAAGAAATGAAGGAGAGCGGCTACCAATTTGTAGAGGTGATGTTGGACGAGAAAATAATGGAAGTCGAACAATTACCTTTAGAGAACATGTCTGATCCGAAAGCGGAGATAGATGGTCTCCAGGAAGATAAATTCCAGTTTGAGACAGAATCTCTGCTATGTTCCGAGTGTGGAGTGActttaaaatctaaatactCTCTCACCCAGCATATGGATCGTCGTCATAAAAAGGAAGTGAACCGTTGCCACCTTTGCGAGACTTGCGGCAAGGATTTTAAATCCAAAGCGCAATTGATAACGCATAACCGTAGCCACACGGGCGAACGTCCATTTAAGTGTCTCCATTGCGACAAGACTTACTCGCAACGTGCAACCCTGCGTATGCATTTAGTAACCCATGGAAAGGAGCGACCCTTCAAGTGCCAGGAATGTGAAAAAACTTTCTATCTTCATCGCAATCTAAAATCCCATCAACGCCGACACAATGGCTTCCGTCCCTTCCAGTGTCCTAGTTGTCCATTGGCTTTTACGAAAAATGCGAATCTTAAGACACATCTCCGCCTGCACACAGGGGAGCGGCCCTTTAAGTGTTCCAAATGTGATATGAGCTTTAGACAAAATCAGCATTTAATCATTCACCTTAGGGTACACAATGATGATCGTCCATACAAGTGTTTGGAATGTGACAagtctttttttgttaatgcaaatttaaagaaaCATATGCGTGTCCATACAGGCGAGAAGCCCTTTAAGTGTGAAACGTGTGGCCAGTCGTTTTCGCATAATCACCATCTGAAGTCACACATTCGTATTCATACGGGGGAACGTCCTTACAAATGCACAGAATGCGATAAGCTATTTGCCTCCAATCAATCATTGCAAAAACATCTCAAGTGGCacagaaataataaagataagcCCTACAAGTGTCTACATTGTAAAAAAGGATTTgatcaatttacaaaactcAAATATCATCTGCGCACTCACAAAGTTCCCAGTGATGTGGAACCGGAAGATCTGGAGGTGGAAAAATCTCTACACAAATGTCCTTACTGCGATGTTAGCTTCGAGACTAAgagaatattggaaaaacatttGACTACACATAAGGAGCGAGCCTTTCAGTGTGAAGAATGTCCCAAAGGATTTTCCCATCGTCAGTCCTTAAAGAAACACATTAAGTCAATACACCATAACATTGCGGAATAA
Protein Sequence: MKEFCRVCMDTSVTLIDIFSKQQATDQDPSLPDMMNDILKENYQVKQDALPQHICLGCVIAAENAYLFKQRCEQSFIHFCQLLKEENTYDSVEKYLTELNTDNHGFQIDVNEEFNKEMKESGYQFVEVMLDEKIMEVEQLPLENMSDPKAEIDGLQEDKFQFETESLLCSECGVTLKSKYSLTQHMDRRHKKEVNRCHLCETCGKDFKSKAQLITHNRSHTGERPFKCLHCDKTYSQRATLRMHLVTHGKERPFKCQECEKTFYLHRNLKSHQRRHNGFRPFQCPSCPLAFTKNANLKTHLRLHTGERPFKCSKCDMSFRQNQHLIIHLRVHNDDRPYKCLECDKSFFVNANLKKHMRVHTGEKPFKCETCGQSFSHNHHLKSHIRIHTGERPYKCTECDKLFASNQSLQKHLKWHRNNKDKPYKCLHCKKGFDQFTKLKYHLRTHKVPSDVEPEDLEVEKSLHKCPYCDVSFETKRILEKHLTTHKERAFQCEECPKGFSHRQSLKKHIKSIHHNIAE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00591118;
90% Identity: -
80% Identity: -