Basic Information

Insect: Drosophila differens
Gene Symbol: -
Assembly: GCA_037043665.1
Location: JBAMAZ010000301.1:565073-571822[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 1.1e-07 7.4e-06 26.1 1.8 2 23 151 172 151 172 0.97

2 9 3.2e-07 2e-05 24.7 1.5 1 23 178 200 178 200 0.98

3 9 1.3e-07 8.6e-06 25.9 1.1 1 23 206 228 206 228 0.98

4 9 8e-07 5.2e-05 23.4 0.7 1 23 234 258 234 259 0.95

5 9 0.00012 0.0081 16.5 3.0 1 23 264 286 264 286 0.97

6 9 0.00044 0.028 14.8 3.3 1 23 292 315 292 315 0.98

7 9 0.00019 0.013 15.9 2.7 1 23 321 343 321 343 0.99

8 9 4.5e-06 0.00029 21.1 0.8 1 23 348 370 348 370 0.98

9 9 0.0061 0.4 11.2 0.3 3 23 378 401 376 401 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	1.1e-07	7.4e-06	26.1	1.8	2	23	151	172	151	172	0.97
2	9	3.2e-07	2e-05	24.7	1.5	1	23	178	200	178	200	0.98
3	9	1.3e-07	8.6e-06	25.9	1.1	1	23	206	228	206	228	0.98
4	9	8e-07	5.2e-05	23.4	0.7	1	23	234	258	234	259	0.95
5	9	0.00012	0.0081	16.5	3.0	1	23	264	286	264	286	0.97
6	9	0.00044	0.028	14.8	3.3	1	23	292	315	292	315	0.98
7	9	0.00019	0.013	15.9	2.7	1	23	321	343	321	343	0.99
8	9	4.5e-06	0.00029	21.1	0.8	1	23	348	370	348	370	0.98
9	9	0.0061	0.4	11.2	0.3	3	23	378	401	376	401	0.94

Sequence Information

Coding Sequence: ATGGACACCATTTGTAGGCTGTGCTTCCAGACAGCAACGTTATTTCAAGTGCCCGGGTATAGCATACCAACGTGCGTGCGCTGCTCGGAACAGTTGACAAACAATTCAAACTTTCATCAGGCGGTACGTGTACAGGACGGCGCAGCCGCTGCTTCTGTGGCGGCCGCTGCGgtagctgctgccgctgcggccTCATCGGCAGCTTCTTCCAGTGACGGTGATGCTGTGGCGGCACAGCTGACGAATGGCAGCGCTGTCGCCGCTGTGctacagttgcaacaacagcaccagcaacagcagcaacaacagcaacaacaacagcaacaacagcagcaacaacaacaacaacagcagcagcaacaacaacaattgcaatcatCAAGTTCTTCCGAGAATCTACAATCGCAGGACGATTCTGAAGATGTGGATCTGATATTCAACGAGGAGGGCTCCTGCCCGCTCTGCAACAAGACGTTCTCACGCAAATCCTCGCTCATGACGCACATACGAAATCACTCGGCTGAGCGCAAATTTGTGTGCAGCTACTGCCACAAAGGCTTTACGCAAGCAGCTAATTTGCGCAACCACGAGCGCATCCACACAAATGATCGGCCGTATCAGTGCGTGGACTGCGGCAAGACATTTACTCAAATCACAAATCTGAACAATCATCGACGTCTTCATACCGGCGAGCGTCCCTTTGTATGCAATGAGCCCGAATGTGGACGCAGTTTTGCCCAGGTGACCAATCTGAACAATCACATGAAGTCACACCACAAGGTGCAGCAGTATTGCTGCAACGTTTGCAGCAAGAAGTTCACGCAGGTCACCTCATTGAATCAGCATCTGCAGGCGCATGCCGGCGTCACCGGCTACTATTGCCCTAGATGTCCGGAGAAGAACTTTAAGCTGCAATCGCAGCTGCATACGCACATGAAGACACATGGTTTGGCCTTTCCGTACGAGTGCAGCAAGTGCGATGAGAAATTTCTACAGCAATCGCATCTCGATCAGCATCTCAAGATGCACGACGagttcaaattcaaatgcgaCATCTGCCCCAGCAGCTTCAATCAGGAGTCGCTGCTCAAGAAGCATGTGCAGCGCCATGTCGAGGGTCGCTATCTCAACTGCCCGGTGGCCAATTGTGCCGAATCGTTTGCCGTGCGACAACATCTCTCCAAACATTTGCTCACCAATCACTCACACCACGAGCTGCCGCCGCCGAAGCGCTCCAAAAAGACCATCACACTGCAATCGCCGCAACAGCCGCTGGCCATGATCGGCCAGCCCCTCTCCCTGCAGCATACGACGGGGCAGCGTGGCAGACCGCcgaagaacaagaacaaaaccTCACTGGCAGCCACGGCCATCAAGATCGAGATCAACGAGCCATTGCACAGTCAGCACATCATCAGCAGTGCCAGCGGACTATCCATCCAGCAGCAGATCAATCAGcatatgcagcagcaggcacagcagcaacagcagcagcagcaacagcagcagcaacaacaacagcaacagcaacaacatctcCATTTGCCCATGGGCCAAGCGGTTAAGGCGCGCTTCATACCCACTAAATAG
Protein Sequence: MDTICRLCFQTATLFQVPGYSIPTCVRCSEQLTNNSNFHQAVRVQDGAAAASVAAAAVAAAAAASSAASSSDGDAVAAQLTNGSAVAAVLQLQQQHQQQQQQQQQQQQQQQQQQQQQQQQQQQLQSSSSSENLQSQDDSEDVDLIFNEEGSCPLCNKTFSRKSSLMTHIRNHSAERKFVCSYCHKGFTQAANLRNHERIHTNDRPYQCVDCGKTFTQITNLNNHRRLHTGERPFVCNEPECGRSFAQVTNLNNHMKSHHKVQQYCCNVCSKKFTQVTSLNQHLQAHAGVTGYYCPRCPEKNFKLQSQLHTHMKTHGLAFPYECSKCDEKFLQQSHLDQHLKMHDEFKFKCDICPSSFNQESLLKKHVQRHVEGRYLNCPVANCAESFAVRQHLSKHLLTNHSHHELPPPKRSKKTITLQSPQQPLAMIGQPLSLQHTTGQRGRPPKNKNKTSLAATAIKIEINEPLHSQHIISSASGLSIQQQINQHMQQQAQQQQQQQQQQQQQQQQQQQHLHLPMGQAVKARFIPTK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00533229;
90% Identity: iTF_00572743;
80% Identity: iTF_00577200;