Basic Information

Insect: Drosophila differens
Gene Symbol: -
Assembly: GCA_037043665.1
Location: JBAMAZ010000286.1:1567136-1568743[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 2.1e-05 0.0013 19.0 0.7 1 23 230 252 230 252 0.98

2 11 9e-06 0.00058 20.1 4.0 1 23 258 280 258 280 0.99

3 11 3.9e-06 0.00025 21.3 0.2 1 23 286 308 286 308 0.98

4 11 2.3e-06 0.00015 22.0 2.1 1 23 314 336 314 336 0.98

5 11 1.2e-05 0.00081 19.7 0.6 1 20 342 361 342 364 0.95

6 11 4.6e-07 3e-05 24.2 4.8 1 23 370 392 370 392 0.98

7 11 1.5e-07 9.5e-06 25.8 2.9 1 23 398 420 398 420 0.98

8 11 8.5e-06 0.00055 20.2 5.1 1 23 426 448 426 448 0.98

9 11 1.2e-05 0.0008 19.7 0.3 1 23 454 476 454 476 0.98

10 11 1.4e-07 9e-06 25.8 0.2 1 23 482 504 482 504 0.97

11 11 6.3e-05 0.0041 17.5 3.3 1 23 510 532 510 532 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	2.1e-05	0.0013	19.0	0.7	1	23	230	252	230	252	0.98
2	11	9e-06	0.00058	20.1	4.0	1	23	258	280	258	280	0.99
3	11	3.9e-06	0.00025	21.3	0.2	1	23	286	308	286	308	0.98
4	11	2.3e-06	0.00015	22.0	2.1	1	23	314	336	314	336	0.98
5	11	1.2e-05	0.00081	19.7	0.6	1	20	342	361	342	364	0.95
6	11	4.6e-07	3e-05	24.2	4.8	1	23	370	392	370	392	0.98
7	11	1.5e-07	9.5e-06	25.8	2.9	1	23	398	420	398	420	0.98
8	11	8.5e-06	0.00055	20.2	5.1	1	23	426	448	426	448	0.98
9	11	1.2e-05	0.0008	19.7	0.3	1	23	454	476	454	476	0.98
10	11	1.4e-07	9e-06	25.8	0.2	1	23	482	504	482	504	0.97
11	11	6.3e-05	0.0041	17.5	3.3	1	23	510	532	510	532	0.98

Sequence Information

Coding Sequence: ATGGAGCAAATTTGCCGTGCATGCAAAATCAACTCCTGCAGTCTGGTGAATATATTCACAGAGGGACAGCCCAGTCTGGCGGAGATGTTGAGCGAGTGCGTTGCCTGTGCAATCAATCGAAATGATGCACTTCCTCAGCAGCTATGCCTCTCCTGCGTCAGCGCTGCACACAATGCGTTTCGGTTGAAGCGCAACTCCGAACAGAAAGAACCAATAACAAATGTTTGCCGAATTTGCAGAAGCAGCTCAATTACGCTACTTGAGATCAATGccaagcggcagcagccactgGGAGAACCCAGTCTAGCGGAAATGATAACAGAGTGCATTGGCTGTCGGACAAATCCCATGGATCAGATATGCCTCTCCTGCATTCTGAGCGTTGAAAACGCCTTTCAATTCAAGCGCAGATGCGAACAGAGCCAGCAATATTTCTGTCCACAAGAGattaaaactgaaattcaaGAAAGTGAAGCAGTTGAACATGTGCTGCCCGATAACAGCTTCGAagtggagcaacagcaatataGCATTAAAATCGAAGTCAGCGATAATGAAGAAGACTTTGAGTGCGAGCAGACTCTCATTATGTTGGTGGAGCAGCATTGTGAAGAGCAACCGGAAGTGAATCCCATGCCTGTCAATAATCATGTTCTAGCAGAGATCGAAGTGGATGCAAAGAAGAAATACATGTGTGAGATTTGCGACAAAAGGTTATCGAGCACTGCTCACCTAGTCGTGCACAGACGCATCCATTCCGGGGAACGTCCGTTCAAGTGTTGCGAGTGTCCAAAGGATTTCACAAGTCGCAAAGTGCTCAAGGATCACATGCGCACCCACACCGGCGAACGGCCATTTCAGTGCGCCCAGTGCCCCAAGGCATTTGGCCGGAATGGTGCTCTGGTCAAGCACATGTTCACGCATACGGGCGAACGTCCCTTCAAGTGCAGCGAGTGTCCGAAAGCCTTCTATCAGAGAGGACACTTGAAGATCCATAATCGCATTCATACTGGGGAGCAGCCATACAAGTGTCCCCATTGCCCCCGGGCCTTTCCACGCAAGGAGTATCTAGTGACGCATCTGCCACTGCATACGGGAGAGAATCCACACCAGTGTCCCCACTGTTCCAAGTCTTTTTCCCGCAGCAAAAACTTAGAGATACACTTGACCACACATACGGGTCAGCAGGCCCATCGGTGTCCCCATTGCAACAAGGCGTTCACCGCCAATTCCAATTTACAAATCCATATCCGGAGTCACACGGGCGAGCGTCCGCACAAGTGTCCCCACTGTGCGAAGGCGTTCAGCCAGAGCGTCTGCCTCAAGAATCACATACGCATCCACACTGGCGAACGACCCTTCCAGTGTGGCCAATGCCCCAAGACTTTTGCCACCAGTGGAGGCCTCTACAGTCATAGTCGTGTCCATTCCGGCGAACGTCCTTTCCAGTGTCCCCAATGCCCGAAGCGATTTCCGCGCAACGAGAATCTACGCAACCACATTGGCATCCACTCCGATGATCGGCCGTACAAGTGCAGCCTATGTCTCAAGCACTTTACCCGCCGCGAGAGTCTGGCCCGGCACAAGCTGATTCatgcaaaaaattaa
Protein Sequence: MEQICRACKINSCSLVNIFTEGQPSLAEMLSECVACAINRNDALPQQLCLSCVSAAHNAFRLKRNSEQKEPITNVCRICRSSSITLLEINAKRQQPLGEPSLAEMITECIGCRTNPMDQICLSCILSVENAFQFKRRCEQSQQYFCPQEIKTEIQESEAVEHVLPDNSFEVEQQQYSIKIEVSDNEEDFECEQTLIMLVEQHCEEQPEVNPMPVNNHVLAEIEVDAKKKYMCEICDKRLSSTAHLVVHRRIHSGERPFKCCECPKDFTSRKVLKDHMRTHTGERPFQCAQCPKAFGRNGALVKHMFTHTGERPFKCSECPKAFYQRGHLKIHNRIHTGEQPYKCPHCPRAFPRKEYLVTHLPLHTGENPHQCPHCSKSFSRSKNLEIHLTTHTGQQAHRCPHCNKAFTANSNLQIHIRSHTGERPHKCPHCAKAFSQSVCLKNHIRIHTGERPFQCGQCPKTFATSGGLYSHSRVHSGERPFQCPQCPKRFPRNENLRNHIGIHSDDRPYKCSLCLKHFTRRESLARHKLIHAKN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00558881;
90% Identity: iTF_00498283;
80% Identity: -