Basic Information

Insect: Drosophila demipolita
Gene Symbol: -
Assembly: GCA_035042405.1
Location: JAWNLI010000025.1:5376586-5379424[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 0.002 0.14 12.6 5.1 1 23 694 716 694 716 0.98

2 5 1.5e-05 0.001 19.3 0.4 2 23 729 750 729 750 0.98

3 5 0.00021 0.014 15.7 1.4 2 23 758 779 758 779 0.97

4 5 0.00064 0.044 14.2 0.9 1 23 784 809 784 809 0.92

5 5 0.42 29 5.3 0.1 1 23 817 841 817 841 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	0.002	0.14	12.6	5.1	1	23	694	716	694	716	0.98
2	5	1.5e-05	0.001	19.3	0.4	2	23	729	750	729	750	0.98
3	5	0.00021	0.014	15.7	1.4	2	23	758	779	758	779	0.97
4	5	0.00064	0.044	14.2	0.9	1	23	784	809	784	809	0.92
5	5	0.42	29	5.3	0.1	1	23	817	841	817	841	0.90

Sequence Information

Coding Sequence: ATGATGGACCGGAAGAAGGTGTTGGAATTGGACAAAATCTGCCGGCTTTGCATATCGGAACGGAAGGAAATGCGTCCGCTATTCAGCGAAAAAGTGCCCGAAATGTTAATGGACTGCACAAGTGTACGCGTAGAGCCCACAGAGGGATGGCCGGACAAGATATGCGTGCAGTGTGTTCATGCCGTCAGCCGGAATCATGCATTCAAAACGCTCGTCGAGCGGAGCGACAAAGAATTACGCGAATATATTCGAGGCCTCACAGTGCGCATGGTCACCGATGAGTCGTTGACGCCGCAGGAgcgcaaacagcaaaagctgctgctgcaaaaacagctcaaacagcaacaacaacagctagaagagcagcagcaattgttaATGCAGCAACAGAtgctccaacaacaacagcaacagcagcaacaacattcgcCCATTTTTGTACtgcagcaaccgcaacaacaacagcaacaattgcagctcaAGCCCAAGAGTAAATTGAAGCCCCTGATTCGCAAGGCCGTCGCACGTCAAACGAAAAAGCAGCAGGAGATTGTGCAATTACTGCCAGAGCCAGCACCACCCCCGCCACCTCCACTGATaacccagcagcaacagcaacaacaacaacagcaacagcagcagcaacaacacatacaacaaatgcagctgcCAACGCTGCAACCGGCGCCAACGCAACTGatgccgacaacaacaacacaacagcaaatcCTACTGCCCAATGGTCAGTTTATCACCACACAGATTGTGACGCCGCAGCTGGCGCAGATAATCAGTTCGCAGGCGACaacaaatgcgaatgcgaCGCAAGCGGCGCAAGCGCAATTTCTGCCACAACTCCTGCAAGCGCACAATGGTCAAACGTTGCAAATTGTCCAGCAACCGAATGGTACACAGACGCTGCAGCTTGTCCAGCTGGTGCCACAGCGCACCATGTCGGCGGCGACGGCAGCgttaaccacaacaacaacagcggagCTGTGTGCGGCGAGTGGAAACGGTGGCGCCTCTTTAGCCGATGCAGATGTGCATCTGCTGGACGATGGTGAAATGGTAGATGATGAAGAGCTGGATGAGGTGTATGAACAGCTCGATGGGAAGGGACACACATTCGAGACAATTGTGCTGGATGATGAGCAACAGCAGGATTATCtcaaggagcagcaacagcagcatcatcaccatcatcatcatcaggtGCTCATCGACGAGGAGTTGACGCATAGCGACATCCATGATCCGGAGCACGACCATGAACAGGAATTGGACCACGAGCAGGACCAGGAGCATGATGGGTATTTTGATGAGCAATTGATGCAGCATGAGGATGGCAGCGGCATTGTCAAACCGGAAGATGAGGATGCAGATAATTTCATCATTGAAGAAATTCAGCTGGATGATGAGGATATGCTTGACGATGGCGAGGGCGGTGAAATGGAGGGCGATGTGGATGATATGACGCCAGTGGATGAATGCGAATATATTACGGATGACCCGGAGCATGGTGGACTCGCCGGCGAAGTCGATGATGAGTTGCACTATGCGATTATGGAGCCAACCGATGGCGATGTGAGCGCCAGCGATATTGAACAGGCCTTCATCGATGTCgatgcacagcagcagcagcaacagttgcacgagcaacagcaacaacaattgcatgagcaacagcaacatttgcaggagcagcagcagcagcaacagcaacaacaatccatGGAACTGCAGAGTTTATCGCTGGAGAATGCAGTTGTGGAGTTTAGACAGGATACGCTCACGCTGCACGTGAACAGCACCCCAAGTCCCACGCCCAGCGCTGCCAAACGATCGcgtcgcaacaacaacaacaaccagcagcagcaacttgtgGAACAACCCTGCAATCATCATCAGCACAGTCCCCCCACAATAAGCAGTAAACTCGCCGCAGCCAATTCACGGCAATTGGTGCAAACTGCATCGGTGATTGCAGCAGCGGGTGCAGATGATAATTACGAGATCGATGCGAACCTGGTGACGGAGTTCATAAGGCAACACACGTCACCACTCGGCTCGGGTCGCTACATCTGCCACTTGTGCAGCACGGAGTTCCGACAGTTCAAAGGCCTGCAGAATCACATGCATTCGCACACCAATTGGATAAGGGCGAACTGCAAGAAGCAGCCGCAATGCGAGATCTGTTTGAAGAGCTTCAAGGGACCCGGCATGTTGCGCATGCACATGAAGACGCACGATGCGGAGACGAGTACGCCggtgtgcaacatttgcaatcGCACGTTCAAATCGAAGGCGATTCTGTATCGGCACCGGCAGACGCATCAGCAGCGTGCATATTGCTGTGGCGTCGCCAATTGTCGCAAGAACTTCTCAAATGCGGCGAATCTGCGCTGGCACGTCGAACGCAAGCATCCCGAGTGTGTGGAGCCCTTCTACAAATGCGGCGAGTGTCTAACGTTGTACGATAATATCGATGGGCTGCAACAGCATGTGGAGACAACGGATCATGGCAGCAATAGTGTGGTCAACGAACAGCTAATTGCCACTGATTCATCAAATGTCACAGCGACGGaggctgcagcagctgcatttaGCGGTGCGGTTAGCATTGTTAGCAACAGCACCGATATGTCCGATATGAATAGCATGATTGCTGCCGCTCCAAATGCATTGGGCGGCGGCACTGCTGGACACACGGGTGACACACATGCCGTTGTCGTTGGCTCCTCCGGCGAGATGTACTTTGTGACGCAGGCGTAG
Protein Sequence: MMDRKKVLELDKICRLCISERKEMRPLFSEKVPEMLMDCTSVRVEPTEGWPDKICVQCVHAVSRNHAFKTLVERSDKELREYIRGLTVRMVTDESLTPQERKQQKLLLQKQLKQQQQQLEEQQQLLMQQQMLQQQQQQQQQHSPIFVLQQPQQQQQQLQLKPKSKLKPLIRKAVARQTKKQQEIVQLLPEPAPPPPPPLITQQQQQQQQQQQQQQQHIQQMQLPTLQPAPTQLMPTTTTQQQILLPNGQFITTQIVTPQLAQIISSQATTNANATQAAQAQFLPQLLQAHNGQTLQIVQQPNGTQTLQLVQLVPQRTMSAATAALTTTTTAELCAASGNGGASLADADVHLLDDGEMVDDEELDEVYEQLDGKGHTFETIVLDDEQQQDYLKEQQQQHHHHHHHQVLIDEELTHSDIHDPEHDHEQELDHEQDQEHDGYFDEQLMQHEDGSGIVKPEDEDADNFIIEEIQLDDEDMLDDGEGGEMEGDVDDMTPVDECEYITDDPEHGGLAGEVDDELHYAIMEPTDGDVSASDIEQAFIDVDAQQQQQQLHEQQQQQLHEQQQHLQEQQQQQQQQQSMELQSLSLENAVVEFRQDTLTLHVNSTPSPTPSAAKRSRRNNNNNQQQQLVEQPCNHHQHSPPTISSKLAAANSRQLVQTASVIAAAGADDNYEIDANLVTEFIRQHTSPLGSGRYICHLCSTEFRQFKGLQNHMHSHTNWIRANCKKQPQCEICLKSFKGPGMLRMHMKTHDAETSTPVCNICNRTFKSKAILYRHRQTHQQRAYCCGVANCRKNFSNAANLRWHVERKHPECVEPFYKCGECLTLYDNIDGLQQHVETTDHGSNSVVNEQLIATDSSNVTATEAAAAAFSGAVSIVSNSTDMSDMNSMIAAAPNALGGGTAGHTGDTHAVVVGSSGEMYFVTQA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00576648;
90% Identity: iTF_00577350;
80% Identity: -