Basic Information

Insect: Drosophila demipolita
Gene Symbol: -
Assembly: GCA_035042405.1
Location: JAWNLI010000025.1:3374090-3376643[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.0053 0.37 11.3 1.1 2 23 333 355 332 355 0.95

2 10 9.6 6.7e+02 1.0 0.3 8 23 381 396 380 397 0.84

3 10 0.073 5.1 7.7 1.0 3 23 413 434 411 434 0.94

4 10 5.5e-05 0.0038 17.5 0.3 1 21 469 489 469 490 0.96

5 10 2.1 1.4e+02 3.1 4.9 3 23 499 520 497 520 0.94

6 10 1.2e-06 8.5e-05 22.7 2.1 1 23 526 548 526 548 0.98

7 10 0.004 0.28 11.7 0.5 1 23 553 576 553 576 0.96

8 10 0.11 7.6 7.2 0.6 2 23 584 606 583 606 0.95

9 10 3.4 2.4e+02 2.5 0.5 2 23 613 634 612 634 0.93

10 10 0.0012 0.087 13.3 1.4 1 23 639 662 639 662 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.0053	0.37	11.3	1.1	2	23	333	355	332	355	0.95
2	10	9.6	6.7e+02	1.0	0.3	8	23	381	396	380	397	0.84
3	10	0.073	5.1	7.7	1.0	3	23	413	434	411	434	0.94
4	10	5.5e-05	0.0038	17.5	0.3	1	21	469	489	469	490	0.96
5	10	2.1	1.4e+02	3.1	4.9	3	23	499	520	497	520	0.94
6	10	1.2e-06	8.5e-05	22.7	2.1	1	23	526	548	526	548	0.98
7	10	0.004	0.28	11.7	0.5	1	23	553	576	553	576	0.96
8	10	0.11	7.6	7.2	0.6	2	23	584	606	583	606	0.95
9	10	3.4	2.4e+02	2.5	0.5	2	23	613	634	612	634	0.93
10	10	0.0012	0.087	13.3	1.4	1	23	639	662	639	662	0.97

Sequence Information

Coding Sequence: ATGGCCGCCGCAGCGGATGCTGCTAAATCAAACGCGCTGCTGGCGACGAACAAAGCGAACAACACAAAATGCCGCGCTTGCCTCGCAGTCGGTCGCCAGACGGTCAAACTGGATGCGAAAATACCAGAACTGAAGACCGTGCGCACCTACGGCCAGGGATTGCGCCAGTGCACGAATATACCGTTAACCGCTCGCTCCGCCGGCGGCTACAGGTGGCCCATGCAGATCTGTTTGCGCTGCTGTCGCGCTCTTGAGGTGGCCATGCATTTTGTGGAACTGACCCTGGAATCGAATCGGAAATTGTTTGCTGAATCGCAAAATCTCAAGACAAATCAAGAAAAAtctgcgacaacaacaatgacggGTGCGTCGAGTGAGCTGAAGCGCAAGGCGAGTGGTAGCAGTGAGCTGTTGAATTGGAATCAATTCAGTCAGGAGTTTGAGCAATTTGTGGAGAGTTACGATGGGGTCACAGCACCCATCGAGGAGAATGTGCTGTATATGCGGGGTGCCAAGATGCCACGCCTCGATACGGACATAACGCCCAACAGGCAGCCACCCGAGGAGGATGATGTTATCTTATTTGATGTAAAGTATGAGAGCAATGATCAAGATCAGGAGGATGAAAACGATGGCTCCGATGCGAAGAACAGCGAAACCTTCTATGACACTAGTATTATGAATGAGAACAACCAATCCGTCGCAGCTGGCATTAAAAGCAGCGccgagaacaacaacaattataattttaataaccaGAACGGTGATGTGGAGGGCGATCTCATCCAGCTTGCCCTCTACATGACGCTCAACGATGatgccaacagcagccaaacaacaacgCACGATTTACAATCCATTGAGTCCATTAAAGCcacattattaaaatCTacggaggaggagcagctggcAGGTACAAGTGGCAGCAGCTTCAGGAGCAGTTTGACCAGCAAATCAACACCCAGCAGGGATATCAATGTCCAGATACCGCTGCTCAGCTGCAGCATGTGCAAACAGACATACACAGAGGCAAAACAGATGAGGACACACTATATGCGGGCCCACAACTGTGATGTGCCAGAGGATGATATCATAGGCCTGACCAAAAatCAAAGCTTTAAGTGTCGTCCATGCATTGATTATGTGACAAACAGTCGTTCTGATATGCAGCAGCATCTTATTGAGCATCACAAAATCGATGGGGATTTTGAAATGTATTGTTATGTGCAGCAGAATTGTCCCGCCTGTAGGCGCATCTTTAAGGATCAACGCTCGGCACGTACACACtacacacgcatgcacactccacaacaaccacaacaacagcagcagcagttgcaacaaccacaacaactacagtTGCAGCCACAATCTAGCAGTTCAGTCGAGCAGCAGCCTCAACAATTTGTGTGCACCTCATGCGATAaagtattcaatttaaagGGCAGCCTACAGGCGCATCAACGTTTTTGCCAGGGGAAGCAGCCGGTGCATTGCACCTTCTGCAAACATCAGTTTAGCAGCATGCGCAAATACgagttgcatttgcaacagGAGCACGCTGTGCACACGTTGCACGAATGCGAGATATGTCAGAAGAGTTTCAAGAACAGCGATTCGTTGGCTGTGCATCGCAAGCGGCACTCGGAGCGACATTTTCACTGTGACAAGTGTTCGCTGAACTATATCAATGCGGCGGAGTTGCGGGTGCACTACGAGCGTGCCCATGTCCACGAGAAGCAGGTTGTAACATGTCGCAGCTGTGACAGCACTTTTCAAAACTACGCCCTGCTTCGCGAACACGAACAGCGCTCGCATCAAAAGCTTAAGATTTGGCGCTGCGACAGTTGCAGCTTTGAGGCGAACTCCCGTGCCCGACTGCGTCAGCATCAGTACGAGCACATGGACTATCCGTACAAGTGCCAGCACTGTCCCGAGGAGTTTGCCGATCGCGGAAAAATCCGTCAACATTCCAAGAAGGCGCACTCGGTGGAGCTGAGCGATGAGCAGCTAGCGGATATGTTTCGGGAACGCATCGGCTACACCAATCGCCATGATGCGTTCAGCAAGACGAACAACTCACTAGAGATACCCGGTTTCAGTGATGACTGCTTTACAGAGCTGAATAGTCTGGGCCTGGACTATGATGATATTTCAACCGATCTCTTCTCAAATTCGATTAGTGCACTGGACACGCTGCTCGAATTGGTACCCTGA
Protein Sequence: MAAAADAAKSNALLATNKANNTKCRACLAVGRQTVKLDAKIPELKTVRTYGQGLRQCTNIPLTARSAGGYRWPMQICLRCCRALEVAMHFVELTLESNRKLFAESQNLKTNQEKSATTTMTGASSELKRKASGSSELLNWNQFSQEFEQFVESYDGVTAPIEENVLYMRGAKMPRLDTDITPNRQPPEEDDVILFDVKYESNDQDQEDENDGSDAKNSETFYDTSIMNENNQSVAAGIKSSAENNNNYNFNNQNGDVEGDLIQLALYMTLNDDANSSQTTTHDLQSIESIKATLLKSTEEEQLAGTSGSSFRSSLTSKSTPSRDINVQIPLLSCSMCKQTYTEAKQMRTHYMRAHNCDVPEDDIIGLTKNQSFKCRPCIDYVTNSRSDMQQHLIEHHKIDGDFEMYCYVQQNCPACRRIFKDQRSARTHYTRMHTPQQPQQQQQQLQQPQQLQLQPQSSSSVEQQPQQFVCTSCDKVFNLKGSLQAHQRFCQGKQPVHCTFCKHQFSSMRKYELHLQQEHAVHTLHECEICQKSFKNSDSLAVHRKRHSERHFHCDKCSLNYINAAELRVHYERAHVHEKQVVTCRSCDSTFQNYALLREHEQRSHQKLKIWRCDSCSFEANSRARLRQHQYEHMDYPYKCQHCPEEFADRGKIRQHSKKAHSVELSDEQLADMFRERIGYTNRHDAFSKTNNSLEIPGFSDDCFTELNSLGLDYDDISTDLFSNSISALDTLLELVP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00560615;
90% Identity: iTF_00525464;
80% Identity: -