Basic Information

Insect: Drosophila demipolita
Gene Symbol: -
Assembly: GCA_035042405.1
Location: JAWNLI010000075.1:2954057-2956561[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 4.8 3.3e+02 2.0 0.7 3 23 36 58 34 58 0.88

2 8 0.043 3 8.4 0.2 2 23 125 147 125 147 0.90

3 8 4.1e-06 0.00029 21.1 3.0 1 23 165 188 165 188 0.98

4 8 8.2e-05 0.0057 17.0 2.1 2 23 298 319 297 319 0.96

5 8 0.0038 0.26 11.7 5.8 1 23 325 347 325 347 0.98

6 8 5.5e-06 0.00038 20.7 2.4 1 23 353 375 353 375 0.96

7 8 1.7e-06 0.00012 22.3 3.0 1 23 381 403 381 403 0.99

8 8 0.00013 0.0094 16.3 3.7 1 20 409 428 409 430 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	4.8	3.3e+02	2.0	0.7	3	23	36	58	34	58	0.88
2	8	0.043	3	8.4	0.2	2	23	125	147	125	147	0.90
3	8	4.1e-06	0.00029	21.1	3.0	1	23	165	188	165	188	0.98
4	8	8.2e-05	0.0057	17.0	2.1	2	23	298	319	297	319	0.96
5	8	0.0038	0.26	11.7	5.8	1	23	325	347	325	347	0.98
6	8	5.5e-06	0.00038	20.7	2.4	1	23	353	375	353	375	0.96
7	8	1.7e-06	0.00012	22.3	3.0	1	23	381	403	381	403	0.99
8	8	0.00013	0.0094	16.3	3.7	1	20	409	428	409	430	0.95

Sequence Information

Coding Sequence: ATGTGTTCCACATCGGTGCTGTGTCCTCTGTGCGCTGTGCCCAGTTTCAATAGCATtgatgcactgcagcagcGTCTGATTAAGGCAGCCAATGGACCCTTGGCCTGCTCATTTCCACACTGTAAAGAACAGTTCCTGGGCCTGGATAAGTTAACCATACATCTGTTTAGTCACACGAGTCTAATGAACAGAGTGGATGAAGTTCCAGCAGTTGCAAAAGTTCCAGAAGCTGTACTTAGTTCGCCACCGCCGCCTGTTGCAGCGCCATCTACTCCGCCCACCGCTGCAGCGCCGAAGCGGCGTGGCAAAAAGTCACGAGCGAAAAATGTGGAACCACCGCCCCAACCACCGCTGCCTACTACACCGCCGGCCCGCTGTGACATCTGTGAGTTTAGTTTCCGCAACGACGAGTTGCGCGACATTCACATCCGGCTGGTCCATGAGAATGGAGTGGAAAGCACGGCAACGCAaccactgcagcagcaggagccgTACAAATGCCATCTGTGCTCGAAGACGTTTCGCATGAAGGGCTCGCTGCGTGTCCATCTCAAAGTGCTGCACACAGTTGGCAGcagctccaacaacaacaacagcaaaaccacttcgagcagcagcaatggcaaccaGATGCTAAATCCGACACCCAAGATAAGCATTTGCGATCGCATTCGACGCAAGGAGGCAACAGCTTTGGCTAATGGCAACACCATCACTTcaggcaacaccaacaacaacaacacaaacaactccaacagcagcaacaacagcaacaacaacaacacccaaCCATATGCTCTAAGTGGCGCCATTTGCATGCTGAAGCAGGACACCACAGGTGCACCAGAGTCAGCGAACAGCTCGGAGTACGGAAGCACGCCCAAGAACTGGGAGTGTGATGTGTGCACCAAGCTCTTCACCACCAAGTACTTCCTGAAGAAGCACAAGCGACTCCACACTGGCGAAATGCCCTATACGTGCCAATACTGCGCTCGCACCTTCACCTTCCAGCAGTCCTACCACAAGCATTTACTCTACCACAGCGAGGTGAAGCCGCACGCCTGCAACATCTGTGGACGCGCCTTTAAGGAGCTATCGACGCTACACAATCATCAGCGCATCCACAGCGGCGAGAAGCCCTTCAAGTGCGAGGTGTGCGGTAAATGTTTTCGGCAACGGGTCTCCTTTCTGGTGCACACCCGCATTCACACTGGGGTTATGCCCTACAAGTGTGAGCAGTGCCAGAAGACTTTCCGGTACAAGGTCTCGCTGCGCACACATAAATGCGCTGCTGGCACTGAGGAGGCGCAGACGCCGGAGCAGCTGATCAAGGCACTGCTGGAATCGAACGCGGTCGGCGTGTTGGGCCATGTGCAGACAGAGCATTCGGCAGCAGGAAGTGGGACAAGTGCTGGGGATCAGGAGGCGTTGCTCTCACAGACGATCGATGACATTGTCGTCGAGAGCTGCCAGAAGCTGGGCATTTGTGGCGTGGAGCCACCACAGCAGGTAATCCTGGACAATGGCAATGTGCACTTCGATGGCAGCAATTCaccgctgcagcagctgcagaatTTGCGCCTCTACTCGCCACCACAGCAGCCGGAGCTGCCCAGCTCCGATGGGGAGCTCTTTCGCCACTTCCTCATGGATGCCACGTAG
Protein Sequence: MCSTSVLCPLCAVPSFNSIDALQQRLIKAANGPLACSFPHCKEQFLGLDKLTIHLFSHTSLMNRVDEVPAVAKVPEAVLSSPPPPVAAPSTPPTAAAPKRRGKKSRAKNVEPPPQPPLPTTPPARCDICEFSFRNDELRDIHIRLVHENGVESTATQPLQQQEPYKCHLCSKTFRMKGSLRVHLKVLHTVGSSSNNNNSKTTSSSSNGNQMLNPTPKISICDRIRRKEATALANGNTITSGNTNNNNTNNSNSSNNSNNNNTQPYALSGAICMLKQDTTGAPESANSSEYGSTPKNWECDVCTKLFTTKYFLKKHKRLHTGEMPYTCQYCARTFTFQQSYHKHLLYHSEVKPHACNICGRAFKELSTLHNHQRIHSGEKPFKCEVCGKCFRQRVSFLVHTRIHTGVMPYKCEQCQKTFRYKVSLRTHKCAAGTEEAQTPEQLIKALLESNAVGVLGHVQTEHSAAGSGTSAGDQEALLSQTIDDIVVESCQKLGICGVEPPQQVILDNGNVHFDGSNSPLQQLQNLRLYSPPQQPELPSSDGELFRHFLMDAT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01324381;
90% Identity: iTF_00518645;
80% Identity: -