Basic Information

Insect: Drosophila demipolita
Gene Symbol: Sry-delta
Assembly: GCA_035042405.1
Location: JAWNLI010000349.1:5735640-5736881[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.00016 0.011 16.1 0.1 2 23 174 196 173 196 0.93

2 7 0.00011 0.0074 16.6 0.1 1 23 202 224 202 224 0.98

3 7 6.8e-07 4.7e-05 23.5 1.5 2 23 231 252 230 252 0.98

4 7 5.2e-05 0.0036 17.6 1.4 1 23 258 280 258 280 0.98

5 7 0.00012 0.0085 16.4 2.7 3 23 289 309 287 309 0.96

6 7 1.7e-06 0.00012 22.2 3.9 1 23 316 338 316 338 0.98

7 7 0.0072 0.51 10.9 0.5 3 23 386 407 385 407 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.00016	0.011	16.1	0.1	2	23	174	196	173	196	0.93
2	7	0.00011	0.0074	16.6	0.1	1	23	202	224	202	224	0.98
3	7	6.8e-07	4.7e-05	23.5	1.5	2	23	231	252	230	252	0.98
4	7	5.2e-05	0.0036	17.6	1.4	1	23	258	280	258	280	0.98
5	7	0.00012	0.0085	16.4	2.7	3	23	289	309	287	309	0.96
6	7	1.7e-06	0.00012	22.2	3.9	1	23	316	338	316	338	0.98
7	7	0.0072	0.51	10.9	0.5	3	23	386	407	385	407	0.95

Sequence Information

Coding Sequence: ATGAACTCATGCTTCTTTTGTGGTGCTGTTGACTTACACGACACTGCAAACTATGAATCGCTCAGTGCTAAGGTGCCATCGTCCAAGAAGTCTGTGTCGCTGGTGCTCACCCATCTAGCCAGCTGTATGAAAACCGAAATGAATCTGAAGAAGGATACAAAGCTTTGTCCGCGATGTTTTCAGGAATTGGCCAACTATGATACGATCATGGTGAACCTAATGGTTGcccaaaaaaaacttacaGCACAATTAAAGGAGGCCCTGAAATCCGAGTTCGAAGACGAAACGCTAATCGATGATTTTGAGGATATAACCGCCCAAGACGATGCCGAAGCTGACGCACTGTTTGGGGAGCTTGTTAAAGAGGACGATCAAGAGATGGAAATTAAGGAAGAATATGCTGATGATAACgctgatgacgacgatgaggaGGACGACTTCCTATGCGATGAGGCCGGCGTTAGGCGAGAAGTTGCCGCCGACGATCAAAAGAAATTCATGGCGAATCGGATTCGGATCGAGTGCGGCTCTTGTGACAAGGTATTCTATGCCCGTTATCAGCTGCAGAAGCACATTAGCGAAGtgcacaacaaattgcagGCGCACGTCTGTCCCATCTGCGGCGTCATCCGCCGCGACGAGGAATATTTAGAGCTGCACATGAACACGCACGAGGGCAAAACGGAGAAGCAGTGCCGCTACTGTCCCAAGAGCTTCTCACGTCCCGTGAACACTCTGCGACACATGCGCATGCACTGGGACAAGAAGAAGTATCAGTGTGAGAAGTGCGGATTGCGCTTCTCGCAGGACAATCTGTTGTACAATCATCGGTTACGGCACGAGGCAGAAGAGAATCCCataatttgcagcatttgcaaTATTTCGTTCAAGTCACGCAAAACATACAATCACCATACTTTGACCCACAAGGAGGATCGACCACGGCATTATTGCACCGTGTGTCCCAAATCCTTTACTGAGCGCTATACACTCAAAATGCACATGAAGACACATGAGGGCGATGTTGTGTATGGAGTACGCGAGGAGGTGCCCACAGATGACCAGGTAGTCGAGGAATTGCAAGTGGATGTGGATGAATCTGAACAGGCCGTCACGGTCATAATGTCGGACAACGATGATCCTACTTCCGGTATTTGTCTCATTTGTAATGTAAACTACGAGAGCAAAAAGGAACTCGCCCATCACTTACAGTATGAACACGACGCCGTAATGAACAATTag
Protein Sequence: MNSCFFCGAVDLHDTANYESLSAKVPSSKKSVSLVLTHLASCMKTEMNLKKDTKLCPRCFQELANYDTIMVNLMVAQKKLTAQLKEALKSEFEDETLIDDFEDITAQDDAEADALFGELVKEDDQEMEIKEEYADDNADDDDEEDDFLCDEAGVRREVAADDQKKFMANRIRIECGSCDKVFYARYQLQKHISEVHNKLQAHVCPICGVIRRDEEYLELHMNTHEGKTEKQCRYCPKSFSRPVNTLRHMRMHWDKKKYQCEKCGLRFSQDNLLYNHRLRHEAEENPIICSICNISFKSRKTYNHHTLTHKEDRPRHYCTVCPKSFTERYTLKMHMKTHEGDVVYGVREEVPTDDQVVEELQVDVDESEQAVTVIMSDNDDPTSGICLICNVNYESKKELAHHLQYEHDAVMNN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00508558;
90% Identity: iTF_00576545;
80% Identity: -