Basic Information

Insect: Drosophila cyrtoloma
Gene Symbol: -
Assembly: GCA_035042485.1
Location: JAWNLH010000667.1:13454307-13458346[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.003 0.2 12.1 0.6 2 23 254 276 253 276 0.94

2 9 0.013 0.83 10.2 4.6 2 23 404 426 404 426 0.91

3 9 0.0062 0.41 11.1 2.3 3 23 496 517 494 517 0.94

4 9 0.00031 0.02 15.2 0.7 2 23 749 771 748 771 0.96

5 9 0.071 4.7 7.8 0.1 2 23 819 841 818 841 0.90

6 9 0.0098 0.64 10.5 3.6 2 23 888 910 887 910 0.96

7 9 0.096 6.3 7.4 4.2 2 23 924 946 923 946 0.92

8 9 0.0037 0.24 11.9 0.3 3 23 1004 1025 1003 1025 0.96

9 9 0.045 2.9 8.5 0.6 1 23 1109 1131 1109 1131 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.003	0.2	12.1	0.6	2	23	254	276	253	276	0.94
2	9	0.013	0.83	10.2	4.6	2	23	404	426	404	426	0.91
3	9	0.0062	0.41	11.1	2.3	3	23	496	517	494	517	0.94
4	9	0.00031	0.02	15.2	0.7	2	23	749	771	748	771	0.96
5	9	0.071	4.7	7.8	0.1	2	23	819	841	818	841	0.90
6	9	0.0098	0.64	10.5	3.6	2	23	888	910	887	910	0.96
7	9	0.096	6.3	7.4	4.2	2	23	924	946	923	946	0.92
8	9	0.0037	0.24	11.9	0.3	3	23	1004	1025	1003	1025	0.96
9	9	0.045	2.9	8.5	0.6	1	23	1109	1131	1109	1131	0.99

Sequence Information

Coding Sequence: ATGGCCGCATCCATATATGCCACCCCACCGCCAGATCTGAGCAGCGAAGATACTGCGCTCTCCGATGTCTCCAACTCATccacactcaacacaaatcgcggcggcggcagcagcaacaacagcagcagcaacacaaacaaccatagcaacaacaacaacaacaataacagtcaCACATTGCAGCCAAATGAAGCCACAGCAgacgcaacaacagcagccacaacaacaacaacaacaacagcagcagcagcagcggcaacaacaacagcaacaacatcaacaatgtCACCcactcaacaacaacttcTGGACACGgagccaaagtcaaagccgGGAAGCAGCACAAATGAAGCAGACATCATCGAGGACGAGGCTGACGGTGACGGGGAAGCGGATTCAACGGCAATGGCTGCgatggcagcagcggcagcaaatgcagcagccatgcagctgcaactgttggaGGCACTGAACGATGCGGCAAAAAAGCGACGCAAACAACACAATCCAAGTCGTCTGGAGGCGCTCAATTTGAGCGGTGGCGAGACGGAAGAGGGGGCAGCGGAGACGGCGCAAAATGCTGTTGTCGACTACGAGGAGAAGCTGTCGAAAATGCTTCTGCCCAAGTCCATTGAGAAGCTGAAGGAGACATTcgagctgttgcagcagcaaaagctgcAGCCAGAAGACATATCAGATGCGGaggaaaaacaacagcaacaacaacaggatcAATCGTTGGTGAACCCCTATCAGACCTATTGCAAGCAATGCGGCGAGAACTTTGAGACGGAGTTCAAGCTCAGTTTGCACATGTTGCAGGACCATCAACTGCAGCAtcaacaggaacagcagcaacagttatCCACGGACGAGCCCATGGATTTGTTATCCTCGATTACAGTAAAGCTGGAACGCGCTGATAGTCCCACCCAGCTggagctacagcagcagcaacagcagctggagctgacGAATggtcacagcaacaacaacaaggagcaCGAGCTCTGGCTACAGGCAATGGCacaacagcatcatcagcaacagcagcaacatcaacaacagtcTGGACTTCCAGGCATGCCGCCCGCTTTTGCGTTTCCCCCAGAGGCAGCTGCTCTGGGCTGGCCACTACTGGGTATGCCTGGCTTTCCTGGCGTCGAGGGTCTCAATCGTCCACCGTTGCGCATCTTTAATCCTGAAGCCTACTGCGAGCTGTGCAACAAGGAGTTCTGCAACAAATACTTTCTCAAGACGCACAAGGCCAACAAACATGGTATCTTTGATCCTGCCGGTGATTTGGCCAGCACcaacagcaacaacaaccacaatggcagcagcaacagcaacaacaacgtcagtagtagtagcagcagctccacTTCCATGTTTCAACAGCTGCAAATGCCACGCGAggtgccaccaccaccaccacaaaaACCAGAGCCACAGCtaacaccaccagcaccaccagcagtaCACTGCGACATCTGTTCCAAGCGCTTTACCAACATCTTTGCCATGCGTCGCCATCGCGCCAAGCAGCACGAGcaggccacgcccactgcctCACCAACGCCCCAAGCGCGTCGCGGCAGCCCCAATGAGCAGCAATCTCCTGTCCAAACGCAGCCTGTGAAGTTAGAGCCGCAGGCGGACACGCAGTCCGTTCCTGAAATAAAGCCGTATCAGTTGCCGGATGGTTTTCGTGAGGATTTCACACTCGAGCAGGAAGAGCTTTCGTTTGCGCCACCTCCGCGCAAGCTGCcagcacagctgcagcagcaggcacgTGAATCAAACTGTGCTCCGGACAAGCTACGGCGATTGGGCGTACTGCTGCCGGAGGCGTTCTGTGAGCTGTGCTGCAAAGAGTACGCGAACAGATACTTTCTGCGCACGCATAAATGGAAGCGGCACGGCGTGTTTGTGCCACCCGAGGATCTGCAGCTAGGCGGCAAAGAGGAGCAGCCACAAATGCCTGCCGGCTGGCCTTTTATGCCGCTCAATCTAATGCTGGCCAAGGCGGCTGcggagcaggaacagcagccaGAGCAGGAGAATCAAAATGAAGACGAGCTGTTGCTCGATGAGCAGCCAAGCAAGCGCATCAAACTGGAACCCTACGACGAGTCGATGCCAGCAGAAAAAGTCGACAACTCAGTGATGGGATTGCAGAATCTCCAAAAGTTACAATcgatgctgcagcagctcaacGATTTCAACGGCAAGAGACCGCTCCCCTGTCATCTGTGCGGACGCGAGCTGGAGCATCAATATGCACTACGTGCGCATCTCATGACGGAGCACGCTAGTCAGCTGTTGCCCGAAGGACATCCCATGCtctaccagcagcagcagcagcagcaacagttgccgcttAAGCTCTCGCCAGCGGGTGGCGGCTCACCGacagcagctgcggctgccacgcccactcccaaTGAGCTGCGCTGCCAGCCGTGCGAGCGTGAGTTTGCCAACAGTCAGGAATTCAAGCAACATATCGCCGAGGTGCATCTGGGCCGCATcccaaccagcagcagcagtccgTTGCGCGAGGGCTTTTACACGCCGGAGCGTGCAACAGTTCCTCCGATTGCCGGTGCTCCTCCAGGACCACCACGGGGTGCTTATACGATCACACCGACGTCCAGCTACTGTGAGATCTGCAACAAGGAGCTGTGCAACAAGTATTTCATGAAGACGCACATGCAACGCATGCACGGCATTGAGATCGAGAATGGCGCCCAGATTGGCGGCGTTGTGTGCAACATATGCAACAAGGAGCTGTGCAGCAAGTACTTCCTACGCGTGCACAAACACAATACGCATGGGATTATCGAGGATGGAGCGCCACTACCCCAGCCACGTGGCCAAAACAGCGCACAGAACGGTATTAAAGCAGatgcccaacagcagcaacaacagcagcagcaacagttgctcgAGCCGGAGGTGAACTTAACAACACTCCCTAGCGACTCTAGTGCTACTAATGAGCTGTGCCCACTGTGCGCACGTCAGTTCCGCAGCGCCAAGTGGTTGCGAACTCATCTGATGAACGAACATGGAGCTGCAGGTGTGGAGAAGCTGCGTGAGCTGgaattgcaacaacagcagccacccAGCTCTACCGGCAGCAAGCCCAACAGTCCCACGCTCAAGATACCCAATGGTAATCCGACTGGCGCCAATAATCTCGCACAGGCGCTGCAGAATGCACAACAGCAGCTCTTTGGACAGATGCAGTTGCCCAAAGGGATGCCGCTTCCCTTGCCGCTTCCTGGCATGTTTGAGCAGACGCCGCGCTTCAAGGAGTACCAGTGCTCCTTGTGTCCGTTCACCACGCCCTATTATGCATTCCTCTTTATACACGAACGCTCGCATGCATTGCTTAACACTGAGGAGACCCATGTGGGCGCCGAGGCGGAGCTGCCACGCAACGACAGGGACAGATCCTTTGCCTTGGTGCAGGGCAAGGCTAGAACCAAGCCCAGCAAAGAGCGTGCCGAAGTGGAGATCGAACCCACGAACCTAACCACCAACAACAGTAACTCAAAGACAGCCACGCCCACGACTACGCCCACAACGTTACCCTCACCAGgtgcagttgcaattgttgctggctCCCCCAAAGTCCGATCCGCGACAGTAACGCCCATACCACGACGAcgcagcaccaccaacacgAACCCAACCACCATCACCACCTCACCCAAGCCCGGAACGCCCAACGGCCTTGGCGCTCAACGTTCGGCGGCCACTTCACCCTTTGAGATGTGTAGCGATCTGGCGAATGGCAGCGGTAAACCCGCCAGCTATGCACAGCCAGACAAGGCCGAGGAGGCATATCAGATGCAGGCCTTCCATTTGGCGCCcgctgatgccgatgctgaGGGCTTGTTTGCGCCAGCACTCGTCTATTTGCCGGTGCGAGTGCGGGCCTCCGAATCGACAACACTAAGCTTTAGGCTGACACCAGCCTAA
Protein Sequence: MAASIYATPPPDLSSEDTALSDVSNSSTLNTNRGGGSSNNSSSNTNNHSNNNNNNNSHTLQPNEATADATTAATTTTTTTAAAAAATTTATTSTMSPTQQQLLDTEPKSKPGSSTNEADIIEDEADGDGEADSTAMAAMAAAAANAAAMQLQLLEALNDAAKKRRKQHNPSRLEALNLSGGETEEGAAETAQNAVVDYEEKLSKMLLPKSIEKLKETFELLQQQKLQPEDISDAEEKQQQQQQDQSLVNPYQTYCKQCGENFETEFKLSLHMLQDHQLQHQQEQQQQLSTDEPMDLLSSITVKLERADSPTQLELQQQQQQLELTNGHSNNNKEHELWLQAMAQQHHQQQQQHQQQSGLPGMPPAFAFPPEAAALGWPLLGMPGFPGVEGLNRPPLRIFNPEAYCELCNKEFCNKYFLKTHKANKHGIFDPAGDLASTNSNNNHNGSSNSNNNVSSSSSSSTSMFQQLQMPREVPPPPPQKPEPQLTPPAPPAVHCDICSKRFTNIFAMRRHRAKQHEQATPTASPTPQARRGSPNEQQSPVQTQPVKLEPQADTQSVPEIKPYQLPDGFREDFTLEQEELSFAPPPRKLPAQLQQQARESNCAPDKLRRLGVLLPEAFCELCCKEYANRYFLRTHKWKRHGVFVPPEDLQLGGKEEQPQMPAGWPFMPLNLMLAKAAAEQEQQPEQENQNEDELLLDEQPSKRIKLEPYDESMPAEKVDNSVMGLQNLQKLQSMLQQLNDFNGKRPLPCHLCGRELEHQYALRAHLMTEHASQLLPEGHPMLYQQQQQQQQLPLKLSPAGGGSPTAAAAATPTPNELRCQPCEREFANSQEFKQHIAEVHLGRIPTSSSSPLREGFYTPERATVPPIAGAPPGPPRGAYTITPTSSYCEICNKELCNKYFMKTHMQRMHGIEIENGAQIGGVVCNICNKELCSKYFLRVHKHNTHGIIEDGAPLPQPRGQNSAQNGIKADAQQQQQQQQQQLLEPEVNLTTLPSDSSATNELCPLCARQFRSAKWLRTHLMNEHGAAGVEKLRELELQQQQPPSSTGSKPNSPTLKIPNGNPTGANNLAQALQNAQQQLFGQMQLPKGMPLPLPLPGMFEQTPRFKEYQCSLCPFTTPYYAFLFIHERSHALLNTEETHVGAEAELPRNDRDRSFALVQGKARTKPSKERAEVEIEPTNLTTNNSNSKTATPTTTPTTLPSPGAVAIVAGSPKVRSATVTPIPRRRSTTNTNPTTITTSPKPGTPNGLGAQRSAATSPFEMCSDLANGSGKPASYAQPDKAEEAYQMQAFHLAPADADAEGLFAPALVYLPVRVRASESTTLSFRLTPA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00499185;
90% Identity: iTF_00616490;
80% Identity: -