Basic Information

Insect: Drosophila cracens
Gene Symbol: -
Assembly: GCA_035042505.1
Location: JAWNLF010000483.1:3043468-3056242[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 2.8 1.9e+02 2.8 2.3 3 23 303 325 301 325 0.92

2 15 1 69 4.2 0.7 3 21 466 484 464 488 0.92

3 15 1 70 4.2 0.4 2 23 510 532 509 532 0.87

4 15 0.039 2.6 8.7 0.6 1 23 549 572 549 572 0.95

5 15 0.17 11 6.7 0.2 1 21 577 597 577 601 0.91

6 15 0.02 1.3 9.6 0.4 3 23 651 672 649 672 0.94

7 15 0.49 33 5.2 0.1 1 21 677 697 677 698 0.92

8 15 9.4 6.4e+02 1.2 0.7 2 23 728 749 727 749 0.90

9 15 0.0018 0.12 12.8 0.6 2 23 762 782 761 782 0.96

10 15 6.2e-05 0.0042 17.5 1.5 1 23 788 811 788 811 0.97

11 15 0.00016 0.011 16.2 0.3 1 23 837 859 837 859 0.98

12 15 1.5 1e+02 3.7 0.7 1 23 866 890 866 890 0.95

13 15 0.69 47 4.7 7.0 1 23 895 919 895 919 0.97

14 15 0.0034 0.23 12.0 3.0 1 23 932 954 932 954 0.98

15 15 0.0013 0.085 13.3 3.4 1 20 960 979 960 981 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	2.8	1.9e+02	2.8	2.3	3	23	303	325	301	325	0.92
2	15	1	69	4.2	0.7	3	21	466	484	464	488	0.92
3	15	1	70	4.2	0.4	2	23	510	532	509	532	0.87
4	15	0.039	2.6	8.7	0.6	1	23	549	572	549	572	0.95
5	15	0.17	11	6.7	0.2	1	21	577	597	577	601	0.91
6	15	0.02	1.3	9.6	0.4	3	23	651	672	649	672	0.94
7	15	0.49	33	5.2	0.1	1	21	677	697	677	698	0.92
8	15	9.4	6.4e+02	1.2	0.7	2	23	728	749	727	749	0.90
9	15	0.0018	0.12	12.8	0.6	2	23	762	782	761	782	0.96
10	15	6.2e-05	0.0042	17.5	1.5	1	23	788	811	788	811	0.97
11	15	0.00016	0.011	16.2	0.3	1	23	837	859	837	859	0.98
12	15	1.5	1e+02	3.7	0.7	1	23	866	890	866	890	0.95
13	15	0.69	47	4.7	7.0	1	23	895	919	895	919	0.97
14	15	0.0034	0.23	12.0	3.0	1	23	932	954	932	954	0.98
15	15	0.0013	0.085	13.3	3.4	1	20	960	979	960	981	0.95

Sequence Information

Coding Sequence: ATGAACGCCGAGTCAGCAGATCAGGAGGACACTCATTTGTGCATCAAATGCAATGCGACAATTGTGGGTCTGGACAAGTACATTGAGCACCGTAAACGGAATTGCCTCAGCACTGGCGGCAATGAGCACCTCTCGAAGCAGGTGGTGACTCCGACAACGACGTCGGCTCCCACCGAGCCAGTATCGCACCCAATCATGCGTAGTACCAACTTGGATCACACCTACGATGGCTTCCACTTTGCAGAGCCGGAGGCACCCAGCAGTTATCTGCGCAAAACGGCATCCAGCCATGGCGGAAAGACGTCCAAGTCCCTAACGGACTCCTATGATCCGACCTACGAGCTGGGAGCCGATCTGTTCTTCTcatcgctgcagctgcaaagtGTCTCAACTGGCGGCAAGACTGGTGCACGGCCGGAGCGTGGTGCCAAGGAGGAACAGGGCTGGCATTCGTCCAGCAACTGCTCCGATCCGCTGCTGAAAGCGGTCCGGGAACACGAGGTAACCCACTTTAAGTCACTCAAATTTGTGCACTCGCCAGAGGCTAGCGAGgaggatgacgacgacgaggactTCGagggcgatgatgatgagcatgAACATGAGCACGAAAATGAACACGATCCCGATCCCGAGCCTGATGAGGATTACGATGGACGTCGCCATTCGCCGCCAACGGTGCCTGCTACGCACACGGGAGGCAAATGGAAGCCGGAGCATCGTCCGCAACTGCAACATACGCATCTGGAACGCATCTCGCCCAGTTGGGATGAGCCGCCTGAGGAGCAGCACGATCATCCGCCTGCGGAGCACACGCACGGCAAATGGGTGCCGGGCAGCAAGCAGCTGGAGTATCGCGAGAACATCGATCTGaccaagctgcagcagccaggcGCCAGCTACTGGTGCAACATTTGCTGTCGTCGCCTCAAGACGCGCCTCAACTACGAGCAACATTTGCGCAGCGCCTACCATCAGCGACGCGCCGATGCCGAGCGTCAGCTGGAGCAGGCCAATTTGGCAAGCTCCAATCTAACACTAACCACCAAGGACCTCCCACAGACGCCGCCGACGGAGCAGCTGCCGcggcgtcgccgtcgtcgtgcCCATTTTCTGCGCTGCGATCTGTGCCGGCACAGCATGGCCCGCCATCTGATGGGCAAGCATCTCATCTCCCACTATCACTATCGccgcctgcagcagcagccgccgagCCAGCTACCCCGGCAGAGCTCCCTGCACGCCATCGTCGAGCACATGGGCAGCATTGTGAGACAGGCGCCGTTCCAGTGTCTACCCTGTCGCTTCTATGCCAACACTGAGCAATCTTTTCagCTCCATTGGCGCTCCTCGACGCATGTGAAGCTGACGGAGCGACTTGGTGGCAACTTCTGGTGCAGCTACTGCCAGTTCGAGTGTGCCAGCAATGAGGAGAtgtggcaacatttgctggGCTCCTCACACAAGGAGGTGCTCTTTGCGATCAATCGTTCGGTGCCCGTTTGCATTGCCCAGCGTCGTCCACTGAGCTGTTCCAGCTGCAGCGCCACTTTCCTGTACAATGCGCAACTGCGTCGTCACTTCGCCGAGGAGCATGTCGGCTTGGTGGCAACGGGAAGCGCTGCCGATGACTATCAGTGTCGCTACCGCTGTGGGATTTGCGGCGTCGCACAGAGATCTCGAGTGGCGTTGCAGCGGCACGAGAAGCACAAGCATCGATTGGCCAAATACTATTGTGCCGTTTGCCGGCTGGAGTTCGAGACGCCGCAAGAGGCTCGACGCCATCGCAGTCTGATGCAGCACAAGCGGCGAGCTTGCCGCCAACTGAGccgcaaatgcagcagcagcagcggcagcactAATCAGCCGGATCGCGAGATTCAACACATGCTGCACGAGGtgctggaggagcagcagccagcagcagcgggagaGCGCCTGGCCAGCCACTGTGTCAGCTGTCCACTTAGCTTTGAGACGCCTCAGGCACTCGTCCAGCATCGTCGCGAGTCGCATCCCATGGACAATCATGCCTGTCTCAGCTGTGGGAGTAGCTTTCAGTCCGCCCAGGCTCTGGGAAGACACACACGCGGCTGCCAGCCCACAGCGTCCACCTCGACAGCTGCAGCTCCCGCTGatccagcttcagctccagctgcaacaTCTCAATCAAAGTCCTGGAATTGTACGCAGTGCAGTTTCACTGCTCAATACGAATCGGATTTGATCTATCATCGTTTCTTTCACACTCATGGCTCGGCAATTGGCAAGAATGACCTGCTTCAGTGTCCGCTGTGCCCCAAACAGTTTCGCAAGGACTCACTGCGTCCGCATCTGCGCAATCATACGAACGAAAGGATCTTCGAGTGCGTCGAGTGCTCGGCCAAGTTTGTACGAAGACACAACCTCAAGAATCACATCGCCACAAAGCATGGCCAAAAGGAGAGAACATCACCAGCTGCTGATAAGCCAACAGTCAAGCAATCGAAAGATGCTGCAAAGCGGAAATATCAATGTGGCACCTGTGGCAAAATACTGGCGAAAAAaTACTCACTCAAAGTACACGAAATGAGCCACGCTGAGGTGGAGCGTCAGCATCGTTGCCACATTAAGGATTGTCAATATGCTGGTCTCACGCCGGAGGCACTCAAGATCCATCTAATCTCACATGCGAAAGGAgaacacaaatgcaaacacgACAACTGCCAGTATGTGGGCAAAAGTGAGCTGCATCTGAAGAGGCACCTCAAGTCGCATGTGCCTGAAAAGGAGCTGGTCGAGGCTGGCAAATGGTTTTCGTGCGATCAGTGCGAGTTCAGGGCCCGGATCAGGGGACATCTGAGGCGGCACATGCGTCGCCACACTGGCGAGAAACCCCATCAGTGTCCGCACTGTGACTTCCAGTGCAGCAGCATGGATAATCTGCGCAAGCATATCGTCAAAACGGGCAAGCATCCTGGCAAGTTCATCTACGAGTGCTCGTCCTGCGATGCCTTCAAGAGCAACAGCTTCAAGGATCATCAACTACATGTGgccacacataaaaacaaattgcccTAA
Protein Sequence: MNAESADQEDTHLCIKCNATIVGLDKYIEHRKRNCLSTGGNEHLSKQVVTPTTTSAPTEPVSHPIMRSTNLDHTYDGFHFAEPEAPSSYLRKTASSHGGKTSKSLTDSYDPTYELGADLFFSSLQLQSVSTGGKTGARPERGAKEEQGWHSSSNCSDPLLKAVREHEVTHFKSLKFVHSPEASEEDDDDEDFEGDDDEHEHEHENEHDPDPEPDEDYDGRRHSPPTVPATHTGGKWKPEHRPQLQHTHLERISPSWDEPPEEQHDHPPAEHTHGKWVPGSKQLEYRENIDLTKLQQPGASYWCNICCRRLKTRLNYEQHLRSAYHQRRADAERQLEQANLASSNLTLTTKDLPQTPPTEQLPRRRRRRAHFLRCDLCRHSMARHLMGKHLISHYHYRRLQQQPPSQLPRQSSLHAIVEHMGSIVRQAPFQCLPCRFYANTEQSFQLHWRSSTHVKLTERLGGNFWCSYCQFECASNEEMWQHLLGSSHKEVLFAINRSVPVCIAQRRPLSCSSCSATFLYNAQLRRHFAEEHVGLVATGSAADDYQCRYRCGICGVAQRSRVALQRHEKHKHRLAKYYCAVCRLEFETPQEARRHRSLMQHKRRACRQLSRKCSSSSGSTNQPDREIQHMLHEVLEEQQPAAAGERLASHCVSCPLSFETPQALVQHRRESHPMDNHACLSCGSSFQSAQALGRHTRGCQPTASTSTAAAPADPASAPAATSQSKSWNCTQCSFTAQYESDLIYHRFFHTHGSAIGKNDLLQCPLCPKQFRKDSLRPHLRNHTNERIFECVECSAKFVRRHNLKNHIATKHGQKERTSPAADKPTVKQSKDAAKRKYQCGTCGKILAKKYSLKVHEMSHAEVERQHRCHIKDCQYAGLTPEALKIHLISHAKGEHKCKHDNCQYVGKSELHLKRHLKSHVPEKELVEAGKWFSCDQCEFRARIRGHLRRHMRRHTGEKPHQCPHCDFQCSSMDNLRKHIVKTGKHPGKFIYECSSCDAFKSNSFKDHQLHVATHKNKLP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00528388;
90% Identity: iTF_00482583;
80% Identity: -