Dcra002595.3


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila cracens
Gene Symbol
-
Assembly
GCA_035042505.1
Location
JAWNLF010000177.1:2694294-2698691[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 9.1e-05 0.0061 16.9 1.6 1 23 330 352 330 352 0.93
2 9 2.2e-08 1.5e-06 28.3 2.6 1 23 358 380 358 380 0.98
3 9 9.3e-06 0.00063 20.1 0.8 1 23 386 408 386 408 0.98
4 9 6.7e-06 0.00045 20.5 1.0 1 23 414 436 414 436 0.97
5 9 3.3e-05 0.0022 18.3 1.4 2 23 527 548 526 548 0.96
6 9 3.4e-09 2.3e-07 30.9 1.6 1 23 554 576 554 576 0.98
7 9 0.0042 0.28 11.7 0.9 3 23 584 604 582 604 0.97
8 9 7.5e-05 0.005 17.2 1.5 1 23 610 632 610 632 0.99
9 9 0.019 1.3 9.7 1.1 1 23 639 663 639 663 0.95

Sequence Information

Coding Sequence
atggccaTAAATTTCTCGGCCTCCTTTGCGGCCTGCATAGCGGCAGGTCTGAAGGTTCCCCGCCAGATAATGTACTGCATCACCCAGGACACGGGCCAGCCGTATGTCCTCTACAAAGACTCACAGGACGCGGAACGCAATGCCGGCGCCATTGGCGCTAGTGCCGCCCAATGGGGCAGTGACATGTACCCAAACATCCAGCAACAGGCCCAGCATCTCagcgcccagcagcagcagcagcagcaacagcagcagcagcaacaacaacagaatgcCACAGCTGCCGCACAAGCGgccgcagctgccgcagccgcCGGCCAGCCCCAGAGTCCGCCCGGTGGCCAGGAGCCACGGGACAATGGCAGCGGCGACGGACGCCAGCAGCAGGTGTCGCCATCCTCGAGTCCGTATCCATCggtggtgcagcagcagcagcaacgggcCAATGGCAATGCCGATGAGGATGCCATGAATCAGCTTGCCAATCAACAGAACTCCGCGCCAAATCCAAACCAAAGCAGCAACGAGCCGCAGCATGCGTCGGCAAATGGCGGCGAGGCTGGCAATCCGCACGTGCAGCAGAATGGTGGCGGTGGCCAGCCGCAGGGCGATCCACGGAATGGCTTCCAGACGCCCGATTATTATGCGCCACGACATGGGGCGGGGCCGCAGGGCGGCATGCTGGCGCCACCCGGCTTTCCGCCGCTGCACTATCTCAAACAGGACGTGCTGCCCATGGAGCAGAATGGCGGTGAATCGTATGCGCTGCCCGAACTGCTGCccggacagcagcagcaacagcagcagcagcaacagaatgGGACGCAATCAAACCCAAATGCTGGCCAAgccaatggcaatgccaatgaGGGCGCTGCGGCGCCCAATGGTCCAGCAACGGGCGCTGCTGGGGCAACGGGAACAACGGGTGGTCGGACGGGACCCGGACGCCCGCAGAAGAATAAGCCGCACAGTGATCTGCGGCTATTCAAGTGCCTCACGTGCGGCAAGGACTTCAAGCAGAAGAGCACACTGCTGCAGCACGATCGGATACACACGGACGCCCGTCCCTTTCCGTGCTCCGAGTGCGGCAAGCGATTTCGCCAGCAGTCGCATCTGACGCAACATCTGCGCATCCATGCGAACGAAAAGCCATTCACGTGTCCGTACTGCTCGCGCAGCTTCCGGCAGCGCGCGATACTCAATCAGCACATACGCATCCATTCGGGTGAGAAGCCCTTCGCCTGCCCCGAGTGCGGCAAGCACTTTCGCCAGAAGGCCATCCTCAATCAGCATGTGCGCACCCACCAAGATGTCTCGCCGCATCTCATCTTCAAGAACGGGCCGCATCCGACGCTGTGGCCCTCGGATGTGCCCTTCCCGGGCGACGAGGCGGACAGCAAGGGTGACATTGCCGCCGCCGGCGGTGGCTACCATGACGATGATTCCCAAGGCACACCCGATGGCAGCGGTGGCATGCACTATCCCTCCTACTTCAAGGATGTTAAGGGACAAAAGATATTGCCGGAGGTGTTGCAGCACATTGGAGTGCGGCCAGCGAATATGCCGCTCTACGTGCGCTGCCCCATCTGCGACAAGGAGTTCAAGCAGAAGACAACGCTGCTGCAGCACGGCTGCATCCACATCGAGTCCAGGCCGTATCCATGCCCGGAGTGCGGCAAACGCTTCCGCCAGCAATCCCATCTCACGCAGCATCTGCGCATCCATACGAACGAGAAGCCCTTCGGCTGCATGTACTGTCCACGCTTCTTCCGCCAGCGAACAATACTGAATCAGcACTTGCGCATTCACACCGGCGAAAAGCCGTATAAGTGCACCCAGTGTGGCAAGGACTTCAGGCAGAAGGCGATTCTGGATCAGCACACGCGCACCCACCAGGTAGGAGATCGTCCGTTTTGCTGCCCCATGCCCAATTGCCGGCGACGCTTTGCCACCGAGAACGAGGTGACGAAGCACATTGACAACCACATGAATCCCAACAGCACCAAAGTgcgccgccagcagcaacagcagcagcagcagcaacaacagcagcaggtgcagcagcagcaacagcagcaacaggtgcaacagcagcagcagcagcaacagcagcagcaacagcagcaaagcaacgttgctgcctctgctgcagTTGTCGCCAATCATTTGATGAACGATGTGAAGAGTCTGGCAGCCCAGCAAttcctcaacaacaacaatcccgCCACGGTGGACAACAAGGCAAACATATTGCCGGCGCGCAGCATGGCTGCCaacgcggcagcagcagcggcagttgcCCAGCAATCGGTTGTGAAGAACGAGCTCTATTTTCCGCAATGCTACGGCCCCCCCTTCCAGCATCCGTTCCacgcccagcagcaacagcagccaagtgCGGCGCACGCGAATGGACCCACGCCGCCCGTGACGGTGACTGTGGCGAATGCGGTGGCACCTGGCGTTGTAGTGCAACAGAATTCGGCCACCTCTGTGcagcaacagcagcagcaacaacagcaacagcagcagcaacaacagcagcagcagcaacaacagtcggTGGTGACTGCAACAGCCACACATCATCCGGCaccacagccagcagcaccaccGACAAGTGCACATCATATCACTTCCGCGGGAGCCGCAACAGCACCGCCCACATCGACACACGCCCCAACGGTGGCAGCGCCGCAGACGGTGACGTTGTCGATAacgttgccgccgccgccatcgGCGCATCTGCCGCATCCGCATGCAGGACATGCGTTGGCGGCGACGCCCAATGGCGTtgcgccaccaccgccgccgcccaCACTGTCACACGCGATACCCAttcacccacacatacactcgaTATTCGGATCTCTATGA
Protein Sequence
MAINFSASFAACIAAGLKVPRQIMYCITQDTGQPYVLYKDSQDAERNAGAIGASAAQWGSDMYPNIQQQAQHLSAQQQQQQQQQQQQQQQNATAAAQAAAAAAAAGQPQSPPGGQEPRDNGSGDGRQQQVSPSSSPYPSVVQQQQQRANGNADEDAMNQLANQQNSAPNPNQSSNEPQHASANGGEAGNPHVQQNGGGGQPQGDPRNGFQTPDYYAPRHGAGPQGGMLAPPGFPPLHYLKQDVLPMEQNGGESYALPELLPGQQQQQQQQQQNGTQSNPNAGQANGNANEGAAAPNGPATGAAGATGTTGGRTGPGRPQKNKPHSDLRLFKCLTCGKDFKQKSTLLQHDRIHTDARPFPCSECGKRFRQQSHLTQHLRIHANEKPFTCPYCSRSFRQRAILNQHIRIHSGEKPFACPECGKHFRQKAILNQHVRTHQDVSPHLIFKNGPHPTLWPSDVPFPGDEADSKGDIAAAGGGYHDDDSQGTPDGSGGMHYPSYFKDVKGQKILPEVLQHIGVRPANMPLYVRCPICDKEFKQKTTLLQHGCIHIESRPYPCPECGKRFRQQSHLTQHLRIHTNEKPFGCMYCPRFFRQRTILNQHLRIHTGEKPYKCTQCGKDFRQKAILDQHTRTHQVGDRPFCCPMPNCRRRFATENEVTKHIDNHMNPNSTKVRRQQQQQQQQQQQQQVQQQQQQQQVQQQQQQQQQQQQQQSNVAASAAVVANHLMNDVKSLAAQQFLNNNNPATVDNKANILPARSMAANAAAAAAVAQQSVVKNELYFPQCYGPPFQHPFHAQQQQQPSAAHANGPTPPVTVTVANAVAPGVVVQQNSATSVQQQQQQQQQQQQQQQQQQQQQSVVTATATHHPAPQPAAPPTSAHHITSAGAATAPPTSTHAPTVAAPQTVTLSITLPPPPSAHLPHPHAGHALAATPNGVAPPPPPPTLSHAIPIHPHIHSIFGSL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00548975;
90% Identity
iTF_00482402;
80% Identity
-