Basic Information

Insect: Drosophila conformis
Gene Symbol: -
Assembly: GCA_035041375.1
Location: JAWNLE010000579.1:3717399-3721374[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 8.4e-05 0.0055 17.1 1.6 1 23 334 356 334 356 0.93

2 9 2.1e-08 1.4e-06 28.5 2.6 1 23 362 384 362 384 0.98

3 9 8.6e-06 0.00056 20.3 0.8 1 23 390 412 390 412 0.98

4 9 6.2e-06 0.0004 20.7 1.0 1 23 418 440 418 440 0.97

5 9 3e-05 0.002 18.5 1.4 2 23 532 553 531 553 0.96

6 9 3.2e-09 2.1e-07 31.1 1.6 1 23 559 581 559 581 0.98

7 9 0.0039 0.25 11.9 0.9 3 23 589 609 587 609 0.97

8 9 6.9e-05 0.0045 17.4 1.5 1 23 615 637 615 637 0.99

9 9 0.017 1.1 9.9 1.1 1 23 644 668 644 668 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	8.4e-05	0.0055	17.1	1.6	1	23	334	356	334	356	0.93
2	9	2.1e-08	1.4e-06	28.5	2.6	1	23	362	384	362	384	0.98
3	9	8.6e-06	0.00056	20.3	0.8	1	23	390	412	390	412	0.98
4	9	6.2e-06	0.0004	20.7	1.0	1	23	418	440	418	440	0.97
5	9	3e-05	0.002	18.5	1.4	2	23	532	553	531	553	0.96
6	9	3.2e-09	2.1e-07	31.1	1.6	1	23	559	581	559	581	0.98
7	9	0.0039	0.25	11.9	0.9	3	23	589	609	587	609	0.97
8	9	6.9e-05	0.0045	17.4	1.5	1	23	615	637	615	637	0.99
9	9	0.017	1.1	9.9	1.1	1	23	644	668	644	668	0.95

Sequence Information

Coding Sequence: atggccaTAAATTTCTCGGCCTCCTTTGCGGCCTGCATAGCGGCAGGTCTGAAGGTTCCCCGCCAGATAATGTACTGCATCACCCAGGACACGGGCCAGCCGTATGTCCTCTACAAGGACTCACAGGACGCGGAACGCAATGCGGGCGCTATAGGCGCTAGTGCCGCCCAATGGGGCAGCGACATGTACCCAAACATCCAGCAACAGGCACAGCATCTCAGcgcccagcaacagcagcagcagcaacagcagcagcagcaacaacaacagaatgcCACAGCTGCCGCACAAGCGgccgcagctgccgcagccgcGGGCCAGCCTCAGAGTCCGCCCGGTGGCCAGGAGCCACGGGACAATGGCAGCGGCGACGGACGCCAGCAGCAGGTGTCACCATCCTCGAGTCCGTATCCATCggtggtgcagcagcagcagcaacgggcCAATGGCAATGCCGATGAGGATGCCATGAATCAGCTTGCCAATCAACAGAACTCCGCGCCAAATCCAAACCAAAGCAGCAACGAGCCGCAGCATGCGTCGGCAAATGGCGGCGAGGCTGGCAATCCGCACGTGCAGCAGAATGGTGGCGGTGGCCAGCCGCAGGGCGATCCCCGGAATGGCTTCCAGACGCCCGATTATTATGCGCCACGGCATGGTGCGGGGCCGCAGGGCGGCATGCTGGCGCCACCCGGCTTTCCGCCGCTGCACTATCTCAAACAGGACGTGCTGCCCATGGAGCAGAATGGCGGTGAATCGTATGCGCTGCCCGAACTGCTGCccggtcagcagcagcagcagcaacagcagcagcagcaacagaatgGGACGCAATCAAACCCAAATGCTGGCCAAgccaatggcaatgccaatgaGGGCGCTGCGGCGCCCAATGGTCCAGCAACGGGCGCTGCTGGCAACGGGGCAACGGGAACAACGGGTGGTCGGACGGGACCCGGACGCCCGCAGAAGAATAAGCCGCACAGTGATCTGCGGCTATTCAAGTGCCTCACGTGCGGCAAGGACTTCAAGCAGAAGAGCACACTGCTGCAGCACGATCGGATACACACGGACGCCCGTCCCTTTCCGTGCTCCGAGTGCGGCAAGCGATTTCGCCAGCAGTCGCATCTGACGCAACATCTGCGCATCCATGCGAACGAAAAGCCATTCACGTGTCCGTACTGCTCGCGCAGCTTCCGGCAGCGCGCGATACTCAATCAGCACATACGCATCCATTCGGGTGAGAAGCCCTTCGCCTGCCCCGAGTGCGGCAAGCACTTTCGCCAGAAGGCCATCCTCAATCAGCATGTGCGCACCCACCAAGATGTCTCGCCGCATCTCATCTTCAAGAATGGGCCGCATCCGACGCTGTGGCCCTCGGATGTGCCCTTCCCGGGCGAAGAGGCGGACAGCAAGGGTGACATTGCCGCCGCCGGCGGTGGCTACCATGACGATGATTCCCAAGGCACACCCGATGGCAGCGGTGGCATGCACTATCCCTCCTACTTCAAGGATGTCAAGGCAGGACAAAAGATATTGCCGGAGGTGTTGCAGCACATTGGAGTACGGCCAGCGAATATGCCGCTCTACGTGCGCTGCCCCATCTGCGACAAGGAGTTCAAGCAGAAGACAACGCTGCTGCAGCACGGCTGCATCCACATCGAGTCCAGGCCGTATCCATGCCCGGAGTGCGGCAAACGCTTCCGCCAGCAATCCCATCTCACGCAGCATCTGCGCATCCATACGAACGAGAAGCCCTTCGGCTGCATGTACTGTCCACGCTTCTTCCGCCAGCGAACCATACTCAATCAGcACTTGCGCATTCACACCGGCGAGAAGCCGTACAAGTGCACCCAGTGTGGCAAGGACTTCAGGCAGAAGGCGATTCTGGATCAGCACACGCGCACCCACCAGGTAGGAGATCGTCCGTTTTGCTGCCCCATGCCCAATTGCCGGCGACGCTTTGCCACCGAGAACGAGGTGACGAAGCACATTGACAACCACATGAATCCCAACAGCACCAAAGTGcgccgccagcagcaacagcagcagcagcagcaacaacagcagcaggtgcagcagcagcagcagcaaacggtgcaacagcagcatcagcagcagcaacagcagcagcaacagcagcaaagcaacgTTGCTGCCTCCGCTGCAGTCGTCGCCAATCATTTGATGAACGATGTGAAGAGTCTGGCAGCCCAGCAAttcctcaacaacaacaatcccgCCACGGTGGACAACAAGGCAAACATATTGCCGGCGCGCAGCATGGCTGCcaatgcggcagcagcagcggcagttgcCCAGCAATCGGTTGTGAAGAACGAGCTCTATTTTCCGCAATGCTACGGCCCCCCCTTCCAGCATCCGTTCcacgcccagcagcagcagcaacagcagccgagTGCGGCGCACGCGAATGGACCCACGCCGCCCGTGACGGTGACTGTGGCGAATGCGGTGGCACCTGGCGTTGTAGTGCAACAGAATTCGGCCACCTCTGTGGTGGCTCAGTGA
Protein Sequence: MAINFSASFAACIAAGLKVPRQIMYCITQDTGQPYVLYKDSQDAERNAGAIGASAAQWGSDMYPNIQQQAQHLSAQQQQQQQQQQQQQQQNATAAAQAAAAAAAAGQPQSPPGGQEPRDNGSGDGRQQQVSPSSSPYPSVVQQQQQRANGNADEDAMNQLANQQNSAPNPNQSSNEPQHASANGGEAGNPHVQQNGGGGQPQGDPRNGFQTPDYYAPRHGAGPQGGMLAPPGFPPLHYLKQDVLPMEQNGGESYALPELLPGQQQQQQQQQQQQNGTQSNPNAGQANGNANEGAAAPNGPATGAAGNGATGTTGGRTGPGRPQKNKPHSDLRLFKCLTCGKDFKQKSTLLQHDRIHTDARPFPCSECGKRFRQQSHLTQHLRIHANEKPFTCPYCSRSFRQRAILNQHIRIHSGEKPFACPECGKHFRQKAILNQHVRTHQDVSPHLIFKNGPHPTLWPSDVPFPGEEADSKGDIAAAGGGYHDDDSQGTPDGSGGMHYPSYFKDVKAGQKILPEVLQHIGVRPANMPLYVRCPICDKEFKQKTTLLQHGCIHIESRPYPCPECGKRFRQQSHLTQHLRIHTNEKPFGCMYCPRFFRQRTILNQHLRIHTGEKPYKCTQCGKDFRQKAILDQHTRTHQVGDRPFCCPMPNCRRRFATENEVTKHIDNHMNPNSTKVRRQQQQQQQQQQQQQVQQQQQQTVQQQHQQQQQQQQQQQSNVAASAAVVANHLMNDVKSLAAQQFLNNNNPATVDNKANILPARSMAANAAAAAAVAQQSVVKNELYFPQCYGPPFQHPFHAQQQQQQQPSAAHANGPTPPVTVTVANAVAPGVVVQQNSATSVVAQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00548975;
90% Identity: iTF_00482402;
80% Identity: iTF_00597545;