Basic Information

Insect: Drosophila conformis
Gene Symbol: -
Assembly: GCA_035041375.1
Location: JAWNLE010000555.1:312519-316583[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.00032 0.021 15.3 1.8 1 23 280 302 280 302 0.99

2 8 2.3e-06 0.00015 22.1 0.8 1 23 307 329 307 329 0.98

3 8 1.1e-07 7.4e-06 26.2 0.2 2 23 338 359 338 359 0.97

4 8 6.8e-07 4.4e-05 23.7 0.3 1 23 365 387 365 387 0.98

5 8 8.4e-08 5.5e-06 26.6 3.9 1 23 393 415 393 415 0.98

6 8 3.1e-07 2e-05 24.8 1.9 1 23 421 443 421 443 0.98

7 8 6.8e-06 0.00044 20.6 5.1 1 23 449 471 449 471 0.98

8 8 0.00023 0.015 15.8 0.5 1 21 477 499 477 500 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.00032	0.021	15.3	1.8	1	23	280	302	280	302	0.99
2	8	2.3e-06	0.00015	22.1	0.8	1	23	307	329	307	329	0.98
3	8	1.1e-07	7.4e-06	26.2	0.2	2	23	338	359	338	359	0.97
4	8	6.8e-07	4.4e-05	23.7	0.3	1	23	365	387	365	387	0.98
5	8	8.4e-08	5.5e-06	26.6	3.9	1	23	393	415	393	415	0.98
6	8	3.1e-07	2e-05	24.8	1.9	1	23	421	443	421	443	0.98
7	8	6.8e-06	0.00044	20.6	5.1	1	23	449	471	449	471	0.98
8	8	0.00023	0.015	15.8	0.5	1	21	477	499	477	500	0.94

Sequence Information

Coding Sequence: ATGAACAACGCACCCGCAACGcacaccacaacaacaactcgaagaagaagcagcagcggcatggGCTTTAAGCATGCGATGCTGCAACGCAGCTACGATCTCGCCGCATCTCCTGCCCCTGCAGAGGCGCCCCAGCAAGTTACGGATTTTAGCATCAGTCGCATTCTGGGTAACGTTGGCAAGGATACTCCACCCAAAAAGAAGGCAGCGgcgagtgctgctgctggcaacattCTCGATCTCTCGAaaagcagtcagcagcagcagcaggcagtgcCGCCCTTGCAGACTGCAACAGCCAATTATGGCTATGCCATGTTGCCACCGGATTTGCTGGCCATGGCCAGTGCAACCAAATTCTATGCACAGTTCTTTCCACACTTGCTGCCTGCCtatgcggcagcagcagctgccgccggcTTCACAACTCCACCCACCTCGCCCTatcagcaacaccagcagcagcaacagcatcagcagcagaagcgttACTTTGCCCCCTATGTGATCAACGGTCAAAGTCCGACACGGGCCAAACCTAGTGCACCCAGTGTCTGCACCCGCGCGGATTGCGTGGAATGCCTGGACTACTATAGACAATTTGGAGCGGGCTACAAGCCGACGCCATTGATTTCGCCGGCGCCTTCTTCGGTCAGCAGTGCGAGCAGCTCGAGGCTGGGCCGGGCAGACAGCGCCACCAACATCTCATTCACCACGGTGACCAACCTGAATCTGAgcacgacagcaacaacaacaatgacaacagcaacaacaacaccagcattGCCAAATTTAgtcgccaacaacaacaacacagcgaCAGCTGAGGAGATCAGCTACAAGTGTCGCATCTGCGATAAGGTCTTTGGATGCTCCGAAACACTGCAGGCGCACGAGAAGACGCATAAATCGCCGCGCTACGAGTGCTCGGATTGTGGCAAAGGATTCTCGCAGCTGCGCAACTATAAATATCATCTGTCCGTGCATCGTGGCACGAAGGAGTTTGCTGCTGAGTGTCCGGAGTGCGGCAAGACCTTCAACGATAAGGGCTATCTGAGCAGCCACATGAAGATCCATCGCAACCGGAAGGAGTACGAGTGTCCATACTGCCCCAAGTCCTTCAATCAGCGTGTCGCCTTCAACATGCACGTGCGCATCCATACGGGCGTCAAGCCGCACAAGTGTGCCGAATGCGGCAAGCGATTCTCCCGCAAGATGCTGCTCAAGCAGCACATGCGCACGCACAGCGGGGAGAAGCCGTATCAGTGCTCCGTTTGTGGCAAGTCCTTTGCGGATCGCAGCAATATGACGCTCCATCATCGGCTACACTCGGGCATCAAGCCATTTAGCTGCCCTCTGTGCCCCAAGGCATTCACCAAGAAGCATCACCTGAAGACGCATCTCAATTATCACACCGGCTGCAAGCCTTACGTCTGCCCACATCCCAATTGCAACCAGGCCTTTACTCAGTCCAGCAATATGCGCACCCACGCCAAGAAGTGCCAATACAGACCGCTGGATGGCGCTCAGCCATTCCCCATGCCacacaagcagctgcagcaaccacaacagcagcagcaatcgctaGCGCTGCCAGCAGTTGCAAGTTTTGTCATGCCACCGGCAGcatttgccactgctgcagcCTCATCCCCCTTTCCGCCGGCCCAGCAAACGCTCCTCAGCAATTTGAGAACATTCCAAGCGATCTGA
Protein Sequence: MNNAPATHTTTTTRRRSSSGMGFKHAMLQRSYDLAASPAPAEAPQQVTDFSISRILGNVGKDTPPKKKAAASAAAGNILDLSKSSQQQQQAVPPLQTATANYGYAMLPPDLLAMASATKFYAQFFPHLLPAYAAAAAAAGFTTPPTSPYQQHQQQQQHQQQKRYFAPYVINGQSPTRAKPSAPSVCTRADCVECLDYYRQFGAGYKPTPLISPAPSSVSSASSSRLGRADSATNISFTTVTNLNLSTTATTTMTTATTTPALPNLVANNNNTATAEEISYKCRICDKVFGCSETLQAHEKTHKSPRYECSDCGKGFSQLRNYKYHLSVHRGTKEFAAECPECGKTFNDKGYLSSHMKIHRNRKEYECPYCPKSFNQRVAFNMHVRIHTGVKPHKCAECGKRFSRKMLLKQHMRTHSGEKPYQCSVCGKSFADRSNMTLHHRLHSGIKPFSCPLCPKAFTKKHHLKTHLNYHTGCKPYVCPHPNCNQAFTQSSNMRTHAKKCQYRPLDGAQPFPMPHKQLQQPQQQQQSLALPAVASFVMPPAAFATAAASSPFPPAQQTLLSNLRTFQAI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00499718;
90% Identity: iTF_00596074;
80% Identity: -