Dcol009884.1
Basic Information
- Insect
- Drosophila colorata
- Gene Symbol
- -
- Assembly
- GCA_035041545.1
- Location
- JAWNLD010000544.1:18306-46747[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 7 0.00021 0.013 15.8 4.6 1 23 459 481 459 481 0.98 2 7 2.2e-05 0.0014 18.9 5.2 1 23 487 509 487 509 0.98 3 7 4e-07 2.6e-05 24.4 0.9 1 23 515 539 515 539 0.99 4 7 2.6e-05 0.0017 18.7 0.7 1 21 551 571 551 572 0.93 5 7 0.53 34 5.1 1.2 2 23 595 617 594 617 0.94 6 7 0.00043 0.028 14.8 2.2 1 20 683 702 683 705 0.94 7 7 0.02 1.3 9.6 0.2 2 20 719 737 718 739 0.94
Sequence Information
- Coding Sequence
- ATGGGCCTCAAATCCATCGCCCTGGGTCCGGAAGAACTGCTACTGCGATCGCAAGCGAAGGTCGACGAGTGGCTGCTGTCGCAGTTCACCAGCGACCAGCGGCACTTAAGCAAAGTCCAGCAAGCCCGACCAGCACCCGAACCGGAACCGGAAccggaactggaactggaagcGGAGTCGGAGTCGAAGAGGCAGCGGGAGCCGGACTCGAGGCTGGCAGCTCAAGAGCTTCAGCTGATCCCGCGCAACACGATTCCGTTGCGTATGTTTAAAATGGATGCAGCTGATTTTTGGCAGCAGGCCCGAGCGCCCTTCGCACTGCACCAACAcacgcaacagcaacagcaacagcaacaacaacagcaacagcacccgCACGCACACCCGCACCCTTTAGCCAGCCAGCAGGAGCAGCATGCCAACCCTACTAATAACAATAACCACCTGCCATTGAATAGCAAATTGGAGCCGAGccaggtgcagcagcagcaacggcaacagcagcagcagcagcagcagcaacagcagcaacaacagccgcatcagcaacagccacaagaGCTACTGCAGCAACATGTCGAGCAGTGCTATGGCAACGAATCCTTTGGCGGGCAGCAGTCGCAGACGCAGCTCAGCAACCACCATTTGCTATTTAATGCAGCCGCCGCGGCAGCCGCGGCGGCGCATCTCAAATCAACGGCCCTGAACAACCACGCGCAGAACAATAGCACCGCCAGCAGCGCAGCCCCGCCAGATCCGCTGGAGAACCCATTGCCCCTCGCCAGCCacaacgccagcaacagcGCCAACATTGCCGTTAAGCCCAAACAAGAGctgggccagcagcagcagcagcagcaacagcagcagcaacagcagcagcaacagctcgcCGATGATCACCGACCGCAGCAAGCGGAGCAAGCGTATAGTGCTGGATTCTTTGGCGGATCCGGAGCCGCCGAGCAGCACTCGCAGctgcaccagcagcaccagcagccgcagcagcagccgccgcagcagctggcCCACCAGGCGCACAGCCCGCTGCTCAACAAGTCGATATCCCAAGGTCTGCAATCTCCGCAACACTCGATAACGCCATCTGGCGGCAGTTCAACACCCGATATCAAGTACAACAACGAAAAACTGGCCAATGAGATTCAGCTACAGCTTTCCAGGTCCAGCAGTGCAGCCGCGATCAGTGAACGTACCCTTGAAGAATGTTGGTCGACCCTGCAACGACTGTTCATGCACAAGAGCGCCATGCAGCAGATCCAACAGCAGATTCCTCGGGTCGGACTGGGGGCGCACGGCGTGGGAGGCACGGCTAGCATGGGCGGCGGTACGACGCCTGGCGCGGAGACAAAGCCACACCAGTGCCAGCAGTGCATGAAGAGCTTCTCCAGCAACCACCAGCTCGTGCAGCACATACGCGTACACACCGGGGAGAAGCCCTACAAATGCTCCTACTGTGATCGTAGATTTAAGCAGCTATCTCACGTCCAGCAGCACACGCGTCTGCACACCGGTGAGCGACCGTACAAATGTCACCTGCCGGACTGCGGTCGCGCTTTCATACAGCTCTCGAatctgcagcagcatctgcGGAACCACGACGCCCAGGTGGAGCGAGCTAAGAATCGGCCCTTTCATTGCAATATTTGTGGCAAGGGATTCGCCACCGAGTCCAGTCTGCGCACGCACACATCCAAGGAGCTACAGCTGCATCTTGGTGTCTTGCAGCAGCATGCGGCACTTATTGGAGGACCCAATGCGACCTCATGCCCGGTATGCCACAAGCTCTTCCTTGGCACCGAGGCGCTGATGGACCACATGAAGCATGTCCACAAGGAAAAGTCGCCGCCGCCCAGCGAGCCACCCACTCAGTTCAGTGAGGGCATTCACAGCGGCGGTGGCAACGGTGGAGCCGGGCCCGGTTCTCTTGCAGCGCAATGCGCGTCCGAATTGAGCTGCGCCCAGCCATCGACGACCAGCGGCTCCAGCTTGAACGACAGCTACCTCGGCAAGCGAAGAACTGCGAACCACCCCTGCCCCGTCTGCGGCAAGCACTACGTTAACGAGGGCTCCCTGCGCAAGCACCTAGCCTGTCATGCCGAAACCTCCCAGCTGACAAGTAGTTTGCGCATGTGGCCCTGCTCCGTGTGTCAGGCCGTCTTCACCCACGAAAACGGTCTACTCACACACATGGACCACATGCGCATGGATCCCAAACATCAGTTTGCGGCACAATACGTTCTGTCTCGAGCGGCGGCAGAGCAACGAGAACGCGAATCCCTATTGGCGGCAACTTTGGCTGCCTCGTCGACGAGTAGCGGGGTCAGAGAGACCTCTCTGCTGCCGTTGGGCGTGACAGCTGGCGGATCGAACTCTTTGTGCCCGTCGCCTTCAGCGAACTCGGAGTGCTCGTCAAATGGTCGCCTGTCCTCGTCGTCGACGTCAGATCAGGAGCAGGACCAGGGATTGAGCGAGAACGAGAACAGCAGCCAAAACAATAACATTAGCAacgtaaacaacaacaataatagcattagcaataacaataataacaactgCAGCTCAAGCAAAATCAACTTGAACGAGCTGCGACTGCCCAGTTCCAGCCAGTACAGCATGGACGCTGAGCTCCATGCTAACAGAATGTCCCTAATGGCAGCTGCCTCAGCCGCGGCGGCCGCTGTGGCTGCCTCTGCCGGCTCAAGGTCTCAGGATGGCGCAATCGAAGCAGTCACTGCCGGCCCAGGCAGCGCGGTGGTCCAGGCGGCAGTTGTGAACTTGGCCGCCGCCATGCGCATGAACAATCCCGCCAATCACCAACAACAGCCAGGCGAACACCAGTTGCACCAGCAAggccatcagcagcagcagcaggcccagcaccaacagcaccagcaccagcaccatcagcagcagctgccccaTCTGCCGCTGCTGTCGCCGCTCGGCAGCCAACAGACGCATCCCGGCAGCAATAGCACGCGGCGCTCGCCGACTATTAACGTGCCCAGCCTGCAGATGCAGACGGACACGTCGTCGGTCATGATGAGCATGATGCGCGGCTCCTTGGACACTAGTCTGGGCGGTATGCATCAAATGGAGGCGCTGCACCATCAACACCACCAGGCGTCCAACTATTCGCAGCACGCCGTGGCGCCCAGTTCACAGCAGACCACGGCACATCCGCAGCACAGCCACCATCCGGAGACGGCGCTGCGCATGCATCAGCAGGCAGAGGCCATAATACGCTCCCATACGGAGGCTGCGTTCCGCCTGGCCGCCTCGGTGGCTGCCACCAATGGCGGCAATGCCAACGCGACGCCCATCGGCACCGGCGCAATCAAAAGTGAGTCCTCGGTGCAGCAACAGCGCCAGGTCAATGGCAGTGAGCTGCACTCGTCGCCGCATCGTTTCCAATCGAGCACGAACCAAAcaccgcatccgcatccgcactCGCAGTCGCATTCACATCCGCATTcacaacaggaacaacaagCAAATCCCCACAACTCATGA
- Protein Sequence
- MGLKSIALGPEELLLRSQAKVDEWLLSQFTSDQRHLSKVQQARPAPEPEPEPELELEAESESKRQREPDSRLAAQELQLIPRNTIPLRMFKMDAADFWQQARAPFALHQHTQQQQQQQQQQQQHPHAHPHPLASQQEQHANPTNNNNHLPLNSKLEPSQVQQQQRQQQQQQQQQQQQQQPHQQQPQELLQQHVEQCYGNESFGGQQSQTQLSNHHLLFNAAAAAAAAAHLKSTALNNHAQNNSTASSAAPPDPLENPLPLASHNASNSANIAVKPKQELGQQQQQQQQQQQQQQQQLADDHRPQQAEQAYSAGFFGGSGAAEQHSQLHQQHQQPQQQPPQQLAHQAHSPLLNKSISQGLQSPQHSITPSGGSSTPDIKYNNEKLANEIQLQLSRSSSAAAISERTLEECWSTLQRLFMHKSAMQQIQQQIPRVGLGAHGVGGTASMGGGTTPGAETKPHQCQQCMKSFSSNHQLVQHIRVHTGEKPYKCSYCDRRFKQLSHVQQHTRLHTGERPYKCHLPDCGRAFIQLSNLQQHLRNHDAQVERAKNRPFHCNICGKGFATESSLRTHTSKELQLHLGVLQQHAALIGGPNATSCPVCHKLFLGTEALMDHMKHVHKEKSPPPSEPPTQFSEGIHSGGGNGGAGPGSLAAQCASELSCAQPSTTSGSSLNDSYLGKRRTANHPCPVCGKHYVNEGSLRKHLACHAETSQLTSSLRMWPCSVCQAVFTHENGLLTHMDHMRMDPKHQFAAQYVLSRAAAEQRERESLLAATLAASSTSSGVRETSLLPLGVTAGGSNSLCPSPSANSECSSNGRLSSSSTSDQEQDQGLSENENSSQNNNISNVNNNNNSISNNNNNNCSSSKINLNELRLPSSSQYSMDAELHANRMSLMAAASAAAAAVAASAGSRSQDGAIEAVTAGPGSAVVQAAVVNLAAAMRMNNPANHQQQPGEHQLHQQGHQQQQQAQHQQHQHQHHQQQLPHLPLLSPLGSQQTHPGSNSTRRSPTINVPSLQMQTDTSSVMMSMMRGSLDTSLGGMHQMEALHHQHHQASNYSQHAVAPSSQQTTAHPQHSHHPETALRMHQQAEAIIRSHTEAAFRLAASVAATNGGNANATPIGTGAIKSESSVQQQRQVNGSELHSSPHRFQSSTNQTPHPHPHSQSHSHPHSQQEQQANPHNS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00617162;
- 90% Identity
- -
- 80% Identity
- -