Basic Information

Insect: Drosophila colorata
Gene Symbol: -
Assembly: GCA_035041545.1
Location: JAWNLD010000233.1:4924853-4927228[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 3.3e-06 0.00022 21.5 0.8 3 23 203 224 202 224 0.96

2 6 0.0001 0.0065 16.8 2.8 1 23 232 255 232 255 0.94

3 6 7.7e-05 0.005 17.2 0.3 1 23 261 283 261 283 0.97

4 6 2e-06 0.00013 22.2 0.5 1 23 292 314 292 314 0.97

5 6 9.3e-05 0.006 16.9 7.5 1 23 323 345 323 345 0.98

6 6 2.8e-05 0.0018 18.6 0.7 1 23 351 374 351 374 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	3.3e-06	0.00022	21.5	0.8	3	23	203	224	202	224	0.96
2	6	0.0001	0.0065	16.8	2.8	1	23	232	255	232	255	0.94
3	6	7.7e-05	0.005	17.2	0.3	1	23	261	283	261	283	0.97
4	6	2e-06	0.00013	22.2	0.5	1	23	292	314	292	314	0.97
5	6	9.3e-05	0.006	16.9	7.5	1	23	323	345	323	345	0.98
6	6	2.8e-05	0.0018	18.6	0.7	1	23	351	374	351	374	0.96

Sequence Information

Coding Sequence: atgttccCGCTGCTGAATCACTCGAGGTTCGTGgtctgccgctgctgcctgGTGGAGCAGCCGCCGCTTTGCCAAAGCATCCGCGACAATGATCAACTCAGCTTGGAGCTGTTGGCCCTGGCGCCCAACCTGCAGATTGTGCCCAGCGATGTGGTCTGCCAGCTGTGCCTGCATCGACTCCACGACGCCCTCGAGTTCCGGCAACGCTGCGAGGAAGCCGAGCTCATTTTGCGTGCCAGGCACGAGCAGGCACTGGACGATGCTCTCGAGTGTCTCGAACGAGAAGTGGGCTGCCTGGAGCAGGCCAAATCCACGGCCATGCAGCTGGAGCCCGTCGACTTCGGTAGCTTGGATCTGTCGGATTTGTTTCGGGGCAATTTCGAGCAGCCAAACACGACGAATGCCGTCTGGGATGTTGGCATCCTAAATACGCCCGTCCATTTGGCGGCAACGTTGGAGCCGTTGGAGGCAAATGCAAACGCGGAGCAGCGGCAGGCGGTCAGCGCTGCTGAAATGCCAGCGCCGGCCGAGAGGCCCAAGCGAAAGCAAGCTTCGCGCAAAGCAGCAACGGCTGGCGCGGGCAGAGCGCCAAAATCGTTGCGGCCATGCACCGAGTGTGAGAAGAAGTTTACGCGTAACTTTCAGCTGAAGTTGCACATGATATCGGTGCACGGCCTGGGCGACGGTTTGCGCTACGAGTGCGAGGTGTGCTCAAAGAGTTTCGCATCGCGTCACAGCCTGCGCTATCATTTCACGTCGCTGCATTCCACGGATCGCCCATTCGCCTGCGAGCTCTGCGATCGTCGATTTGTGCTGCGCACCCAACTGATCTCGCACGCCCGCATGCACACGGGCGAAACAAAGCCGCGCATCTTTGACTGCAGTGTCTGCGGTAAAACGTGGCCAACGAAATCGGATCTGCGTACGCATATGCGCTCACACGATCCGGACATGTCCAAGCGACCATATAAATGTGATAAGTGCCACAAGGCGTTCTTCACACGCGGCCATCTCAACTCTCATCATTTGGTCCACACCGGCGAGAAGCCCTATGCCTGCACCTATTGCGACAAGTCGTATCAGAGCGTTGGCAATCTGAACAATCACACCTTGCGACAGCATTCGAATATTATCGAAACGCAGCTGAATCTCAATTATACAGACTCTTTGGACATTGAAAGTTAG
Protein Sequence: MFPLLNHSRFVVCRCCLVEQPPLCQSIRDNDQLSLELLALAPNLQIVPSDVVCQLCLHRLHDALEFRQRCEEAELILRARHEQALDDALECLEREVGCLEQAKSTAMQLEPVDFGSLDLSDLFRGNFEQPNTTNAVWDVGILNTPVHLAATLEPLEANANAEQRQAVSAAEMPAPAERPKRKQASRKAATAGAGRAPKSLRPCTECEKKFTRNFQLKLHMISVHGLGDGLRYECEVCSKSFASRHSLRYHFTSLHSTDRPFACELCDRRFVLRTQLISHARMHTGETKPRIFDCSVCGKTWPTKSDLRTHMRSHDPDMSKRPYKCDKCHKAFFTRGHLNSHHLVHTGEKPYACTYCDKSYQSVGNLNNHTLRQHSNIIETQLNLNYTDSLDIES

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00530424;
90% Identity: iTF_00561218;
80% Identity: -