Dcol003504.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila colorata
Gene Symbol
L
Assembly
GCA_035041545.1
Location
JAWNLD010000175.1:293681-303421[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 17 1.1e-05 0.0007 19.9 2.9 1 23 162 184 162 184 0.98
2 17 0.37 24 5.6 6.2 1 23 190 212 190 212 0.97
3 17 1.8e-07 1.2e-05 25.5 3.2 1 23 218 240 218 240 0.99
4 17 1.3e-05 0.00085 19.6 0.4 1 23 246 268 246 268 0.99
5 17 0.013 0.82 10.2 0.1 2 23 342 366 341 366 0.92
6 17 0.00081 0.052 14.0 0.2 2 23 401 423 400 423 0.95
7 17 0.11 7.3 7.2 0.4 1 23 506 528 506 528 0.95
8 17 0.015 0.99 10.0 0.1 2 23 536 557 535 557 0.91
9 17 0.00069 0.045 14.2 0.1 1 23 565 589 565 589 0.94
10 17 3.5 2.3e+02 2.5 1.0 2 23 625 647 624 647 0.95
11 17 0.0027 0.17 12.3 1.1 1 23 695 718 695 718 0.97
12 17 0.0068 0.44 11.1 1.6 2 23 903 925 902 925 0.96
13 17 0.12 7.9 7.1 0.1 1 23 931 953 931 953 0.92
14 17 0.83 54 4.5 0.3 2 23 961 982 960 982 0.93
15 17 0.42 27 5.4 1.2 1 23 1083 1105 1083 1105 0.94
16 17 0.032 2.1 8.9 0.0 1 23 1115 1137 1115 1137 0.95
17 17 0.0008 0.052 14.0 2.0 1 23 1142 1164 1142 1164 0.97

Sequence Information

Coding Sequence
ATGATGGCTTTAAAGATGTTGTATCGCGGTCCCAGTTCGCGTTTGgagaatttaattgaaaagatTCAAGCCACCAAGGAGATTACGAATAACGATATGTACAGCACGCACACCTCCTCCAGCTACTCGCCCAGCATCTCCGATGGCACTTTGACGCCCAATTCGATGCCGCAGCTGGCGGCACAGGCCGAGGAGTCCACGGCGGAGACCAAGGCGAATGGGGATGCTGCGTCCGCAtcggaggagcagcagcaggagccaATCAAGCCGAAGCGGCCGGCACATttgcatcatcatcatcaccatcattatcatcatcagcagGCGCTGAAAATTGCCAACAAACTGCGCAAAATCAATAAGGATGCGAAACTGGTAGCTGGGATAGGATCGGGCAGCGCAGGACAACCCGGACACAATGCAGCGGGAGCAAAGTTTGATAAGTTGACAGCCGAGGGCATTAAAAGTCGTGGCGACGGCTCCTATCAGTGTCAGTTCTGTGATAAATCATTTCCGCGTCTCGGCTACTTGAAGCATCACGTGCAGAGCCATGCCGAACATTTGCCTTTCAAGTGCGAATACTGCGCCAAGCTGTTCAAGCACAAGCGCTCCCGAGATCGCCATAAGAAGCTCCACACGAACGAGCGGAACTACAAGTGTCCGCATTGCGAGGCGGCTTTCTCCAGAAGCGACCATCTGAAGATCCACATGAAGACGCACGACATCCAGAAGCCCTTCCAGTGCAGCATGTGCAATCGTGGCTACAACACGGCCGCCGCCCTCACCTCGCACATGCAGAAGCACAAGAAGAACGCCGCCATTCTAGCCGCTGGCGGCAATCCCAATGCACTCAACTACAGTCCGCGTTCGACGGGATCTGCCTCGATCTCCAGCAATGGCAGCCTGCACAAGCGACGCTATGCGCTGGCCTTGGCCTCCGACAGCAGTCCGAGCCGGCTGGAGTTTCCCAAACGGGCGCGTGCTCAGCTGGCGgcgaccacgcccacgccgacgccgctgctgcgctgcAGCTACTGTCCTAAGGTCACCGAGTTTAGCAGCCTGGAGCAGCTGAATGCGCATCTGCAGAGCGCCCACGAGCAGCAGACGGCAGCCGGCGGGGAGCGCGATCGGAATCGGGATCGGGATCGTGATCGGGATCGGGATGGGGCGGAGCTGGCGACGAACGGCTTTCAGCTGAGCTGCGAATACTGCACGATGAAGTTCGCGAATATTGCCGCACTCTTCCAGCACATGCGCGCCACGCACCTGGACCGGCTGAGCAGCCCGAACTCCTACTACGAGCACTTCAATCGGCTGGCCACGGCGGGCACGTTCAGTCCCCGGCTGGCGCTGGACTTGCCCAAAATCAAACCGGATGCGGGCAGTCCCCGACGGGAGGCGCTCGCGCCGGAGAGGCCCGAACAGCAGGAGCTGCCCACGGATTTGAGCAGCAACAAGCGGCGTCCGTTGACGCCGCCGTCCATGGCCGGCGGGGCAGCGCCACCTGGCGTCTTCCTGTGCAATCAGTGCAATGCGGGACTGCCGGACTTCGAGAGCTTCCGCAACCATCTGAAATCGCACATCGCCGAGGGCATGCAGCTCAGCTGTCCGCACTGCGGCCTGAATCTGCCCGAGCAGAGCGAGTTCGAGCGCCACGTGGTCGCCCACTTTCTGATCAGCAGCTCCGAGTTCAAttgcagcgccagctgcggCAAATCGTACGCCAAGGCGGAggaactgcagcagcatctgcTCAGCGAGCAcgtccagcagctgctgaagTGCATCCTCTGCTCGGAGCTGTGCGAGAATCGAATGTCCATGCAGCTCCATTTGGCCTGCGCCCACAGCCAGGAGACGAAGCTGTTGCGCTGCAGCGCCTGCTTGGAGCTCTTTCGCACCGATGCTGATTTCCATGTGCACGTCAAGACGCGCCATCAGCTGgccgggcagcagcagctgagtgtgggcgtgggcgtggccgttcCGCCCTCGAATCCGCTGCAGTGCATGTTCTGTCGCGTCGTTTGCGCCTCGGAGCTGGAGATGCATTTCCATTTGGCGGCGCATGCGCGCCAATTTCGCTGTCCCAGCTGCCCGGAGACCTTCCACGTGGAGTTCCTGCTCGACCGGCATATGCAGAGCCAGCacggcggcgccggcggcgtcAAGGCCAAGGATCaaggcgccgccgccgccgccagcatGGGCAGCCTCTATGTGAatgcgctgctgccgccgctggcagcggctgcggcggccgccgctgcggcgaccaacaacaacagcaatctgCACATCGACTACAATGTGGCGTTTAAGGGCTTGtttggtggtggtgctggtggtggcggtggcggagGGGGCGGTGCCACGCCCGCGAGTGCACAGGCCAAATTCTATAGTCCGCTGCAGGTGGACACGAAGGCGGCGCAGCAGGCGCCGCATCCGGCGCTCATGTACGGCCTGAGCCAGCGCTATCTGATGGAAATGTACGCGGCCAAGGCGAATTCGCCGGCCACAAGTGTGCCAGAGTTGCCACCGCAAGCGGCGCCAGTTGCGTCCGTCGGCaacgccaccgccaccgcctcCACGTCGGGCAACTACAGCTGCGGCATGTGCGAGCGTCAGGATCTGCGCAGCGAGGCGGAACTGCACTCGCATCGGAAGCTCGCCCACAATCTGAAAACGGGCGTCAGCCTGAGATGCGCCTACTGCTCCGGCAATTACAAGTCGCGGgcggagctggagcagcacaTGAAGAGCTGTCACAATTCGAGCGGCAAGCACAAGTGTCTCATTTGCGACGAGATCTTTCCGTCGCCCGCGATTCTCGCCGAGCACAAGCTGCAGCACTCCAAGGTGGGCCAGTCCGGCAAGTGCGCCCACTGtggccagcagctggagcaTGTGGCCGCCTACCGGGCGCATCTCGGCGAGCATGGCAACGATGGCAATCTGCCGATGGCGTGCATCTGTTGCCGTCAGACGCTGCACTCGGAGTTCGAGCTGAGCCTGCACGCCAAATTCCATACGAAATCGTCGCCGGGCTGCGGCAGCCTGCAGGAGCCGGTGTGTGCACTGTGCCTGGAGCCGCTGCCGGGCGCCGGCGAGACCGCCAAACTGTGCGACAAATGCTGTCGCAAGCACAATCTCAACGGCAAGCGCCACAAGGAGCCCGCCCTgctggcggctgctgcggcgccaAGCGCGGCCACGGCGGGCACGGCCGCCTACTTGGAGCATCGCTGCAATCTGTGCAAGCTGATTTTGCCGCACGCCCAGAAGCTGCAGGAGCATCTGGTGGAGCACACCTTTGCCGGCACCGAGCAGCGCGGCTTCAATTGCTATATCTGCTCGGCGGTCTTCACCGCGCCCGCCGGCCTGCTCAGCCACATGGGCGAGCACGGCGCCCGGCCGTACGATTGCAATCTGTGCACGGAGAAGTTCTACTTTCGTGCGGAGCTGGAGCATCATCAGCGCGCGCACGAGCTGCGCCAGCCGGCCAAGCAGACGCCCAAGCAGGAGACGCTCAGCTCGGCGGCCAGTTCACCGTTGGCGCCGCCCAGTCCCCTACGAGCGGTCAAGCAGGAACTGTACGAATCGGAGCCGGCCACGTCGCCCGGCGCGGAGCCAGCTGCGCCCGACGAGGAGGAGTACATCGAGGTGGAGCAAGTGCCGCAGGAGACACAGCGCACGGGGGAGCTGCTCAGCGCCGAACggtccagcagcagcgcctaA
Protein Sequence
MMALKMLYRGPSSRLENLIEKIQATKEITNNDMYSTHTSSSYSPSISDGTLTPNSMPQLAAQAEESTAETKANGDAASASEEQQQEPIKPKRPAHLHHHHHHHYHHQQALKIANKLRKINKDAKLVAGIGSGSAGQPGHNAAGAKFDKLTAEGIKSRGDGSYQCQFCDKSFPRLGYLKHHVQSHAEHLPFKCEYCAKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASISSNGSLHKRRYALALASDSSPSRLEFPKRARAQLAATTPTPTPLLRCSYCPKVTEFSSLEQLNAHLQSAHEQQTAAGGERDRNRDRDRDRDRDGAELATNGFQLSCEYCTMKFANIAALFQHMRATHLDRLSSPNSYYEHFNRLATAGTFSPRLALDLPKIKPDAGSPRREALAPERPEQQELPTDLSSNKRRPLTPPSMAGGAAPPGVFLCNQCNAGLPDFESFRNHLKSHIAEGMQLSCPHCGLNLPEQSEFERHVVAHFLISSSEFNCSASCGKSYAKAEELQQHLLSEHVQQLLKCILCSELCENRMSMQLHLACAHSQETKLLRCSACLELFRTDADFHVHVKTRHQLAGQQQLSVGVGVAVPPSNPLQCMFCRVVCASELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGAGGVKAKDQGAAAAASMGSLYVNALLPPLAAAAAAAAAATNNNSNLHIDYNVAFKGLFGGGAGGGGGGGGGATPASAQAKFYSPLQVDTKAAQQAPHPALMYGLSQRYLMEMYAAKANSPATSVPELPPQAAPVASVGNATATASTSGNYSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCSGNYKSRAELEQHMKSCHNSSGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCAHCGQQLEHVAAYRAHLGEHGNDGNLPMACICCRQTLHSEFELSLHAKFHTKSSPGCGSLQEPVCALCLEPLPGAGETAKLCDKCCRKHNLNGKRHKEPALLAAAAAPSAATAGTAAYLEHRCNLCKLILPHAQKLQEHLVEHTFAGTEQRGFNCYICSAVFTAPAGLLSHMGEHGARPYDCNLCTEKFYFRAELEHHQRAHELRQPAKQTPKQETLSSAASSPLAPPSPLRAVKQELYESEPATSPGAEPAAPDEEEYIEVEQVPQETQRTGELLSAERSSSSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00538445;
90% Identity
-
80% Identity
-