Dcol005667.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila colorata
Gene Symbol
RREB1
Assembly
GCA_035041545.1
Location
JAWNLD010000295.1:1699067-1705450[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.035 2.3 8.8 0.8 1 21 234 254 234 256 0.93
2 13 0.00033 0.021 15.2 0.2 1 23 266 288 266 288 0.98
3 13 1e-05 0.00067 19.9 3.9 1 23 294 316 294 316 0.98
4 13 0.18 11 6.6 1.6 2 20 527 545 527 547 0.93
5 13 0.0082 0.53 10.8 0.1 1 23 703 725 703 725 0.97
6 13 1.2e-05 0.00078 19.7 0.7 1 23 735 757 735 757 0.99
7 13 0.00081 0.053 14.0 2.0 1 23 763 786 763 786 0.97
8 13 0.003 0.19 12.2 2.1 1 23 1054 1077 1054 1077 0.95
9 13 8.5e-05 0.0055 17.1 0.3 2 23 1424 1445 1423 1445 0.97
10 13 0.14 9.2 6.9 6.3 1 23 1451 1474 1451 1474 0.97
11 13 9.2 6e+02 1.2 3.4 1 23 1588 1611 1588 1611 0.78
12 13 0.0083 0.54 10.8 0.5 3 23 1674 1694 1672 1694 0.96
13 13 0.0013 0.085 13.3 4.8 1 23 1700 1722 1700 1722 0.99

Sequence Information

Coding Sequence
atgctggccacacagcagcaacaacaactcacggcaactgcagcagcagcaacagcaactgcagcagcagcaacagcagcagcaacaacagcagcagctgcgacaacaacaacaacaacaacagtagctCTGGAGGATGCGATTATGGAGCGACAGCGTCAGGATTCCAGCACCTCGGAGTCCTCGCTGGAGCATCTGGACTTGGGCCGCACGCCAAAGAAGCTCTGCAGCGTTGGCGGCGCGCCGCAGCCGACGTCAACGCCGCACGAGGCGACGTCGCGCAAGCGCAAgctgcgccagcagcaacaacagcaacaacaaccgtcGCATTTGCTGTCCGACGAGGAggacgagcagctgcagcagctgcagcgcctgcgCGACAAGCAGCGACGCGGcgtcgctgccagcgccaGCATCGTCGTCGACTACAGCGCCAGTGGCGACGCCAGTTCGCTGCGCAAAAAGTTTCGACTGAACCGCAGCGCGGCCAACGGGGAGCTCGGCGAGTCCGGCTTCGTGGATGGCAGCGCCAACAGCGCCTTTCTGCAGAGCAGCgccggcggcgtcggcggcggcagcgctgcCCAGACAACGGCAGCGACGTCGGCGAGCAGCAGCTCCGGCGGCTCTTCGCCGCAGGGTCTGTGCCATTCGAGCGCCGAGTCCGGCATCGGCGCCGGCGACGAGCACATGAAATATCTGTGCCCCATCTGCGAGGTGGTCTCGGCCACGCCCCACGAGTTCACCAACCACATTCGCTGCCACAACTACGCCAACGGCGACACCGAGAACTTCACCTGCCGCATCTGCTCCAAGGTGCTGTCGTCGGCCTCCTCGCTGGACCGGCACGTGCTGGTGCACACGGGCGAGCGTCCGTTCAACTGTCGCTACTGCCCGCTGACGTTCACGACCAACGGCAACATGCACCGCCACATGCGCACCCACAAggagcaccagcagcagcagcagcaacagtcacagcagcaacagtcacagcagcaacagtcgcagcagcagcagcagcaacagcagcagtcgcaacaacagttgcagcagcagcagcagcgacgccagcaGAAATTGTCCGCTCGCGGCGAGAGCTACGAGAGCGACGCCAGCTGCTCGACGGACGTgtccagcagcggcagcagcaacagcgccagcagcagcagcagccacaacaacaacaacagtcagcagacgaacaacaacaatgtggagccggaggaggagcagcagcagcagcagcagcagcaactgttgccggCGTGCAAGCGACGCCGCCACAAGaccaacatcaacaacaacaacatcatacTGAGCGACGAGCGTGAGCGCGACCTGGCCTTGGACTCCGATCCGGAGGAGGATGGCCGGAGCAtggacgtggacgtggacgtggacgtggCCCAGCTGATCACGAGCACGCCGGACGTGGCCACGTTGCTGGCCTCCGGCGGCAGTTCGCCGTCGCCGGCCGCGCTGGCCAGCTGTCCGGCCTGCGATACGGCGGAGTTCGAAACGCTGCCGGCGCTGTGGACGCACCTCGACGAACAGCACGCGGACATAGCCGCCAAGTGTCGCGACTGCGATGTGATCTACGCGACGCACCGCCAGCTGCAGGCGCACAGCTGTCGAGGATCAGGATCGGGATCGGGCGTGGGCTTGGCGCCGCTGCTGGGCGCGAGCAGCTCGCCGCTGCACAAGCAGGAGCCGGACGAACTGGAGCCGGAACACGAGCACGATGAGGAGCACGAACACGATCACGAACACGAACACGATCgggagcaactgcagcaggaACGCGAACTGGACAGCGAGGAGCGCGACGAGTTCTTTCATCAGCTctatttgaaaaacaaatccgGCGCATTGCCCTCGCCGATCAAGCACGAGCTGTCCGATCAGCGCCAGGATCTGGCCGATATACAGAGCATCCTGCAGATgaccagctccagctgcacgTCCAGCTTTCTGCGCAACTTCGAACAGTCGGTGAACACGCCCTGCTCCAGCCAGTACAGCCTGGACGGGCGCGAGGTCGAGGAGGAGGCCCAGGATGCGTTCACCAGCGAATTCCGGCGCATGAAGCTGCGCGGCGAATTTCCGTGCAAATTGTGCACGGCCGTCTTTCCCAATCTGCGCGCTCTGAAGGGCCACAATCGGGTGCATCTGGCCGCCGTCGGCGCCTCGGGCCCGTTCCGCTGCAACATGTGTCCGTACGCCGTCTGCGACAAGGCGGCGCTGGTCCGGCACATGCGCACCCACAACGGCGACCGGCCGTACGAGTGCGCCGTCTGCAACTACGCCTTCACCACGAAGGCCAACTGCGAGCGGCATCTGAGGAATCGGCATGGCAAGACCAGCCGCGAGGAGGTGAAGCGCGCCATTGTCTACCATCCGGCGGAGGATGCCAGCTGCGAGGAGCCGGCCATGGTGGGCAAGCCAGGACACAATCAGGAGCTGGCCGAGCTCAGCTATCGATCGCTGACGCCGCCGCCCGGCGAGCTGAGCAGCTGTTCCTCCTCCTCGCAGCTGAAGCACATGCTGCTCGGCGAGgcgacgccgacgacgacggcgacgaagACGCCGCTCAAGATACAGGTGAAGAGCCTGGATCAGCTGGTGGAGAAGCCGGCGGAGCAGCTGGCCGAGCAGCTGGCGGAGAAGCCGGCCATCGATCTCAGCATGGATGTGCTCGATCTGAGCAAGAAGCCGACGGCCACGCTGGAGCTGCTCGAaagggagcgggagcgggagagggagcgagaaagggagcgggagcgggagcgagAGCGGGAGCACgaattgctgctgcaacagcagcaacaacaacaacagcaacaacaacagctcttTGGCGATCCGGCCACGCAgtacgtgcagcagctgctgcgcagcTTCATGTTCCAGCAGAGCTCCGGATTTCCGTTCTTCGGCTTTATGGCGCCGCCCGCAAATCTGGACAAATCCGCTCcgacggcggcgtcggcggcggcagcggcgacagCACTGCCCGCCGCGGTGGCGCCCGTTGCGGcggtgccgccgccgctgggcCTGCCGCTGGCCGCCGGCGGACCCGTCAAGATGGTCATCAAGAACGGCGTCCTCATGCCCAAGCAGAAGCAGCGCAGGTACCGCACGGAGCGGCCCTTCGCCTGCGAGCACTGCACGGCGCGCTTCACGCTGCGCTCCAACATGGAGCGTCATGtcaagcagcagcatccgCAGCACTATGCGCAGCGCCAGCGTAGCGGCCATCATGTGCTGCGCGGCCGCGCGGCCAATTCGGgcgcggcggcagcagcagcggcggcagcggcggcggcagcggcagcgatgAGTAATCTGAGtcagcatccgcatccgcatccgcatgcACATCCGCATGCACTGGGACATCCACATGGACATGGGCATGGCCAtgcgcatccgcatccgccgCCCATTTCCGAGCAGGTGAAGTACGCGATTCTGGCGCAGCAGCTGAAGGCGCGCAAGGATACGGatctgctgcagcaggcgctggCGCACGGCTCCAGCAGCGTCGTCGTCAATCCGCTGCTccactacaactacaacaagagCCAAccaggcggcggcggcggcggcggcagcaatgGGCACGTTCTCGATGACGATGAGCCGCCCAAGCTGATCATtgacgaggacgaggaggacGATTTCGAGGATatggacgaggaggaggaggaggaggaggaggaggagcagcagcagctcgaggagggcgaggagcagcagcagccggaacAGCTCGAAGAGcagccggagcagcagcagcagctgccggaACCAGCTGCAAAGCCGGAGCAGCCGGCAGTGGAGAAAAAGagagctgccacgcccacgccaaCGCCCACAGCAACGGCCACACCAACGCCCACACCAACGCCCACGACCACGCCCAGCACAATGAAGATCCTGATCGCCCAGGCCGAGTCCGTGGCCAAATCGCTTAAGGACGTCGCCAGCTCACCGTTCAAGGAAGAATCTCAGGACCTGGTGCCGGTGGCCAAGCTGGTGGACAACGCGACCAGCAATCAGGTCTCCTTCAACAGCTATTTCCGGCCGAGCGACGTCGCCAACCACATGGAGCAGAGCGACGAGGAGGGCCTCGTCGCCTccggcagcgccagcgagagcaacaacagcggcaccGAGGAcgtcaccagcagcagcagcagcagctgctgcaacgaGCCCAAAAAGAAATCGGCCTACAGCCTGGCCCCCAACCGGGTCAGCTGCCCGTACTGCCAGCGCATGTTCCCCTGGAGCAGCTCGCTGCGCCGCCACATCCTCACCCACACCGGCCAGAAGCCGTTCAAGTGCTCGCACTGTCCGCTGCTCTTCACGACGAAGAGCAACTGCGACCGGCATCTGCTGCGCAAGCACGGCAACGTCGAGTCGGCCATGTCCGTCTATGTGCCCACCGAGGATGTCAGCGAGCCGATACCGGTGCCCAAGTCCGTCGAGGAGATCGAGCTGGAGGAGCAGCGACGCCGGCAGGCGGCGGAGCTGgaacgggagcgggagcgCGAACGGGAGCGGGAACGGGAGCGCGAACGGGAGCGCGAGCGGGAACTGGAGCGTGAAAGGCAGctggagcgggagcgggagcgcgAGCTCATCCAGCAGCTGACGGCCGCCGCGCAGCTGGGCCAGCAGATGGCCGCTGCCGTTGCGGCCGCAGCCAGCGCCGGCGAGACGGAGTCCAATGGCAGCGAGCTGCCGTACAAGTGCCACCTGTGCGAGTTCAGCTTCGGCGAGCGGCTGCAGTGCCTCGAGCACATCAAGCAGCTGCACGAGCACGAGTTCGccctgctgctggccaaagGCGCCATCGAaacggagcagcagcaacagcagcagcagcaacaacaacaacaattggccgCCCATTCCGAGGATGAGTCGAcggccggcggcggcgccaaCGCGAATTCGCTGCGTTCCGGCAAATATCCGGACTACAGCAACCGGAAGGTGATTTGCGCGTTTTGCGTGCGCCGCTTTTGGTCGACGGAGGACCTGCGCCGGCATATGCGCACCCATTCCGGCGAGCGGCCGTTCCAGTGCGAGATCTGCCTGCGCAAGTTCACGCTGAAGCACAGCATGCTGCGGCACATGAAGAAGCACAGCGGACGCAGCCACAACGGGGAGCAGGGCGGCTCCGATTGCTCCGACGACGAGCAGCTGGCCACGCCGCCCagcacgcccacgcccacgcccacgtcGACAGCCATGGCCACGCCCCTgcccaccaacaacaacaacaacaactgccacaacaacaacaacagcaacaagcaggGCTTGCGGCTGCCCAAGCTGCACGAGCTGCTGGACAAGGCGAACGAGTGGCGCGTCAGCCGCCTGGGCGAGCACAAGGAGAATATCGCGGAGGCGAcggcggccacgcccacggcgacggcggcggcggcggccagcGGCGATCTGATTGGCAATCTGCTCGGGATCAGCGATCAGGGCATACTCAACAAGCTGCTCTCCTCCGCGGACGAGGCCGCCAAGCTCCTGGGCGTGGACAAGTAG
Protein Sequence
MLATQQQQQLTATAAAATATAAAATAAATTAAAATTTTTTTVALEDAIMERQRQDSSTSESSLEHLDLGRTPKKLCSVGGAPQPTSTPHEATSRKRKLRQQQQQQQQPSHLLSDEEDEQLQQLQRLRDKQRRGVAASASIVVDYSASGDASSLRKKFRLNRSAANGELGESGFVDGSANSAFLQSSAGGVGGGSAAQTTAATSASSSSGGSSPQGLCHSSAESGIGAGDEHMKYLCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCPLTFTTNGNMHRHMRTHKEHQQQQQQQSQQQQSQQQQSQQQQQQQQQSQQQLQQQQQRRQQKLSARGESYESDASCSTDVSSSGSSNSASSSSSHNNNNSQQTNNNNVEPEEEQQQQQQQQLLPACKRRRHKTNINNNNIILSDERERDLALDSDPEEDGRSMDVDVDVDVAQLITSTPDVATLLASGGSSPSPAALASCPACDTAEFETLPALWTHLDEQHADIAAKCRDCDVIYATHRQLQAHSCRGSGSGSGVGLAPLLGASSSPLHKQEPDELEPEHEHDEEHEHDHEHEHDREQLQQERELDSEERDEFFHQLYLKNKSGALPSPIKHELSDQRQDLADIQSILQMTSSSCTSSFLRNFEQSVNTPCSSQYSLDGREVEEEAQDAFTSEFRRMKLRGEFPCKLCTAVFPNLRALKGHNRVHLAAVGASGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSREEVKRAIVYHPAEDASCEEPAMVGKPGHNQELAELSYRSLTPPPGELSSCSSSSQLKHMLLGEATPTTTATKTPLKIQVKSLDQLVEKPAEQLAEQLAEKPAIDLSMDVLDLSKKPTATLELLEREREREREREREREREREREHELLLQQQQQQQQQQQQLFGDPATQYVQQLLRSFMFQQSSGFPFFGFMAPPANLDKSAPTAASAAAAATALPAAVAPVAAVPPPLGLPLAAGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCTARFTLRSNMERHVKQQHPQHYAQRQRSGHHVLRGRAANSGAAAAAAAAAAAAAAAMSNLSQHPHPHPHAHPHALGHPHGHGHGHAHPHPPPISEQVKYAILAQQLKARKDTDLLQQALAHGSSSVVVNPLLHYNYNKSQPGGGGGGGSNGHVLDDDEPPKLIIDEDEEDDFEDMDEEEEEEEEEEQQQLEEGEEQQQPEQLEEQPEQQQQLPEPAAKPEQPAVEKKRAATPTPTPTATATPTPTPTPTTTPSTMKILIAQAESVAKSLKDVASSPFKEESQDLVPVAKLVDNATSNQVSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSSSCCNEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRQAAELERERERERERERERERERERELERERQLERERERELIQQLTAAAQLGQQMAAAVAAAASAGETESNGSELPYKCHLCEFSFGERLQCLEHIKQLHEHEFALLLAKGAIETEQQQQQQQQQQQQLAAHSEDESTAGGGANANSLRSGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCEICLRKFTLKHSMLRHMKKHSGRSHNGEQGGSDCSDDEQLATPPSTPTPTPTSTAMATPLPTNNNNNNCHNNNNSNKQGLRLPKLHELLDKANEWRVSRLGEHKENIAEATAATPTATAAAAASGDLIGNLLGISDQGILNKLLSSADEAAKLLGVDK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-