Dcol008548.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila colorata
Gene Symbol
-
Assembly
GCA_035041545.1
Location
JAWNLD010000490.1:9858661-9861897[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.012 0.77 10.3 1.6 2 23 143 165 142 165 0.90
2 12 3.7e-06 0.00024 21.3 2.6 2 23 179 201 178 201 0.96
3 12 0.21 14 6.4 8.8 2 23 480 501 480 501 0.97
4 12 1.2e-06 8.1e-05 22.8 2.8 1 23 507 530 507 530 0.96
5 12 0.00038 0.024 15.0 0.4 1 23 535 558 535 558 0.96
6 12 0.00015 0.0099 16.3 4.6 1 23 576 598 576 598 0.96
7 12 0.00014 0.0092 16.3 1.2 1 23 603 625 603 625 0.98
8 12 3.4e-05 0.0022 18.3 1.7 1 23 631 653 631 653 0.95
9 12 0.00011 0.0074 16.6 0.8 1 23 659 681 659 681 0.98
10 12 3.5e-07 2.3e-05 24.5 2.7 3 23 689 709 688 709 0.99
11 12 7.8e-08 5.1e-06 26.6 1.7 1 23 715 737 715 737 0.99
12 12 1.6 1e+02 3.6 5.2 1 19 742 760 742 765 0.88

Sequence Information

Coding Sequence
ATGCCCGACAGTTGCGGCCAGTTCCACGCGGAGCGCGTCTGCCGCGTTTGCCTGCGCGAGGTGGGCGACTTCTACTTCATCTACGACGAGGCGCCCGTAGAGCAGGGCGCAAACATGGCCCAGATACTGAACGAGTGCACGCGATACAGCTGCGAGCGCTACGACAAGTTGCCACACCACATGTGCGACACCTGCATTAAGGCTGCCCGCCAGGCGTACCGCTTCAAGCTAGACGCAGAGAAGGCCTATCGCTCGCTGGTGGCGCTCTTGGGGCGCACCCCCCTAGCCCGGCCCAACAGCAGCGAAGTGTGCACACAGACGGAGCAGGTGGCCTTGCTGCCGTGCGGGATCTGCAGCGATCAGTTCCTCAACATCCTCGAGCTGCGACTGCATCGCAATCGCCAGCACAAGCACAGGGAGCAGCTCAAGTGCCAGTTGTGCGACGAGCAGTTCCAGCAGATGCGCCACCTGCGCAACCATCTCGTCGAGCAGCACGATCAGCAGGCGGCCGCGTCGCTGCTGCGCCGGCGTCTAGAGTGTCGCCTGTGTCAGCGCTCCTTCGCCCGGCGCGATCACATGCAGCGCCATATGCGCACCGCGCACCAGGCTGATGGCCGAGGTCGGCTGGTCCGGTCGCTGGCCGAGCAGCAGGTGGTTCAGTCTGCAGCGGCCTGGCCGCCCATCGATGAGGCGACCATGCACAGTGGCGACGAGCTGGAGTCGGCTGCCGTTCTCTTCAACGAGCCGGCTGGCTGCTCCGACGAGGATGGGAACCTTAACTGCGAGAGTGGCTATCAATGCCACACAAATCCCATATCGAGCAACGAGGAAGCCGACGATGAAGACGTTCATGCCGAGGCTAAGCAATCGCTCTGGCTGCACATTAAGCCAGAGCCGGAAGCGGACGCGGAAACGGAAGCGGATCTAGAACACTGCCCGGCGCATGTGCAGCGCGAGAATCGCAGGAAAAAGGCAAATTTTAAAGCGGCCGCCCACACTGACTCAGAGGACGAGCACGAGATTGCAGAGAAGCAGGAAACTGCGTTCACTGCTTGGACAGCAGAGGTTAAAGAGGAGCCTCTGGTCACCGGCGGCGAGCAACAGTTGTCCATTAAGCAGGAGCGGCAGCGCCTTGACAGCGTTAAAGAAGACGAGGACGAAATGGAGGCGGCAACAGCTAACGTCCCATATAGTGCAGATGACGATGAAGGCGGGGAAGAGTTTGGCAACGAGGAGAGCGAcattgatcaggacgacgacgacgacgacgatgattaTGAGGACGAACCGAATGCAAACCTAGAGGCGTATTCCGAGGACAAGTCCCAGGTGGCCCAGGTGGAGATTGTGCGCGAGTATCTGGAGAAGCCAACAGCTGGCAAGCAGCGACGTCGTCGACGCAAGAAGCCGAGCGATTCCGAACCGAATCCGGAGAATCGGTGTGACATTTGCATGCGCACCTTTTCCCGCCATTGCCATTTGTTGCGCCACAAACTGTCGCACTTGGAGAAGAAGCCGCACAGCTGCCCGCACTGCCCCAAGGCGTTCGCGCGCAGTGACCATTTGAAGGCGCACGTGCAGAGCCTGCACGGCAACAAGGAGCACAAGTGCGTGCTGTGCGACGCGGCGTTTGCCCGCCTCGACGCCCTCGAGCGGCACAAGATGAGCAAGCACAATGGCGAGGGCGTGGACGCCAACAGCGAGCTGAAGCTGCAAATGAGCGAGCACACGTGCGAATACTGCGCCAAGCGGTTCTCCAGCAAGACTTACCTGCGCAAGCACACGCTGCTCCACACCGAATTCCTCTACGCGTGCAAGAGCTGCGACGAGACATTCAAGGAGCGCCAGGAGCTGCGCAGCCACGAGAAGACGCACACCGGCCAGCGAAACTTCCTCTGTTGCATTTGCGGCGACAGTTTTGCGCGCAACGATTATCTGCGCGTCCACATGCGGCGGCACAACGGCGAGAAGCCGTACAAGTGCCGTTTTTGCGTCAAGGCATTCCCACGCGCCACAGATCTTAAGGTACATGAGCGCTATCACACGGGCACCAAACCCAATCTGTGCAACACGTGCGGCAAGAGCTTCCATCGTGCCTACAATCTCACCATACACATGCGCACCCACACCGGCGAGCGGCCATACAAGTGCGACCAGTGCTCGAAGAGCTTCAGCCAGAGCAACGACTTGAAGGCGCACATACGACGCCACACGGGCGAGCGCTACAAGTGTCCGCACTGCGATGCCTACTTCCTGCAGCTATACCACATGCGCAACCATTGCCTCAGTGCCCACAACAAGCACATTGAGACCAAAACGGGACGCCTGCAGCGCACCGGGCTGCTGGACGAGCCCAATCACTCGCATCTGACCACTGTGGTAATGCCGCCGGCCCGTTTCCAGCAGTCAACGCCAGATCCGCACGCGATAGCGACGGTTAACGCACAACTGCCGGCACCGTCGGCACCGccaattgccacgcccattctTCATTCGCCGGTCACGTACAGCACAACGTCGCCAGTGTCGGTGTCTGTTCCAGTGCCGGATGCTGGCGGATTTGTGGGTGCTGCGAATAGCGCCACAGCTACGGCGACGGCACCCTTTGCGGCATTCAATATAGCGCCCGTGGTGATGGCGCATCTCATGTACAACCATGgcggcagcagccagcagagCAATGCCAGCGGCAGTGAGGCGGGAAAATAG
Protein Sequence
MPDSCGQFHAERVCRVCLREVGDFYFIYDEAPVEQGANMAQILNECTRYSCERYDKLPHHMCDTCIKAARQAYRFKLDAEKAYRSLVALLGRTPLARPNSSEVCTQTEQVALLPCGICSDQFLNILELRLHRNRQHKHREQLKCQLCDEQFQQMRHLRNHLVEQHDQQAAASLLRRRLECRLCQRSFARRDHMQRHMRTAHQADGRGRLVRSLAEQQVVQSAAAWPPIDEATMHSGDELESAAVLFNEPAGCSDEDGNLNCESGYQCHTNPISSNEEADDEDVHAEAKQSLWLHIKPEPEADAETEADLEHCPAHVQRENRRKKANFKAAAHTDSEDEHEIAEKQETAFTAWTAEVKEEPLVTGGEQQLSIKQERQRLDSVKEDEDEMEAATANVPYSADDDEGGEEFGNEESDIDQDDDDDDDDYEDEPNANLEAYSEDKSQVAQVEIVREYLEKPTAGKQRRRRRKKPSDSEPNPENRCDICMRTFSRHCHLLRHKLSHLEKKPHSCPHCPKAFARSDHLKAHVQSLHGNKEHKCVLCDAAFARLDALERHKMSKHNGEGVDANSELKLQMSEHTCEYCAKRFSSKTYLRKHTLLHTEFLYACKSCDETFKERQELRSHEKTHTGQRNFLCCICGDSFARNDYLRVHMRRHNGEKPYKCRFCVKAFPRATDLKVHERYHTGTKPNLCNTCGKSFHRAYNLTIHMRTHTGERPYKCDQCSKSFSQSNDLKAHIRRHTGERYKCPHCDAYFLQLYHMRNHCLSAHNKHIETKTGRLQRTGLLDEPNHSHLTTVVMPPARFQQSTPDPHAIATVNAQLPAPSAPPIATPILHSPVTYSTTSPVSVSVPVPDAGGFVGAANSATATATAPFAAFNIAPVVMAHLMYNHGGSSQQSNASGSEAGK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00547491;
90% Identity
-
80% Identity
-