Basic Information

Insect: Drosophila cognata
Gene Symbol: tra
Assembly: GCA_035041535.1
Location: JAWNLC010000099.1:1398560-1401103[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 4 1.2 79 4.0 6.5 1 23 132 154 132 154 0.94

2 4 0.0058 0.37 11.3 2.8 3 20 178 195 177 198 0.93

3 4 1.4e-06 8.7e-05 22.8 3.6 1 23 204 226 204 226 0.98

4 4 0.0001 0.0065 16.9 1.3 1 23 232 255 232 255 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	4	1.2	79	4.0	6.5	1	23	132	154	132	154	0.94
2	4	0.0058	0.37	11.3	2.8	3	20	178	195	177	198	0.93
3	4	1.4e-06	8.7e-05	22.8	3.6	1	23	204	226	204	226	0.98
4	4	0.0001	0.0065	16.9	1.3	1	23	232	255	232	255	0.97

Sequence Information

Coding Sequence: ATGGAAACTGCGATGTGCCGCATTTGTTTAAACACTACGGTGACGCTGGTGGAAATATTCGCGAAGCGTGAGCAATCCGATAAGGCCAACCCGGAGCCTAGCCTGGCGGACATGCTGAACGAGTGCGCCGATTGTCACATCAAATCCAACGATTCGCTGCCACAACAAATATGCCTCAGCTGTGTGCTTTGCGCTCAAAACGCGTTCAGCTTCAAGCGAAAATGTGAGCAGAGCTATCAGCAACTGGTTGCCAAACGCAAGTTGCGGCAAGAAATTGCAGCGAAAGAAACGACATCGAAAACGGTGCCAATCAAAAAAGAGCTGCTGGATGGGCTCGACATAAAACAGGAACACGAAATTAAAGTCGAGCCAGCGAGCAGTGAATCCCCACTCTATAAATGCCCATATTGTTGCAAGAAATTCACTCACTTGAGGATTTTGAGTTTGCATAAGAAATGGCATGCCGAGAATCAGCATAGCAACCGCAGAGTCGGCCCAAAGCCGAGCAAAGTGGAGAGTAAATCGAAAATCTGCTCCATTTGCAAGAAGAAATGTAAATCAGTTTCGTTGCTGCGCAAGCATCTCTGGTCCCACAGCGATTTGCGTCCATTTCCCTGCACCCTGTGCCCGACCAGCTTCCAGTTCAATTCGCATCTTAAGCGGCATATGCGCAGTCATACTGGCGAGCGTCCGTATCAATGTCCGTTCTGTCCGGAAGCCTTTTCTAGAAGCGACTATTGCCGCGCTCACATGGACAAAATGCACAGCGGTTTAACATTCACCGGCAAGCTAATGCGGCGTTCGCGCGACAGGGGAAGGGCAaagaagagagagaaggagaagcTGCCCTACTTCGCAGACGTGGGACGTGAGCGCGACCGAATGCGCAATCTGAGGCAACACCACAGAACGGAACGCAGTctgacgccgccgccgcagcgaCGCCCACGACTGAGATCTCGTTCGCATTCCCCGCAAACAAATTATCGCCAGCGCCGGCGTTCAAGGAGCGCTGAGCGTAGTCACCGCACCAGCCGCAATATGAGGCATGCCTCTCCATACGCGCATCGCCGACGCAGTCGAAGTCGCTCGCGAACACCACGCATTATAACTGTGCCGGTGCCAGTGCCAGCAGCTGGTTATCCTTACGCCTACGACTGGCCGCGACAGCCAAATTTTCATGCTATGTTTGCCCCGATGCCATTTGCCATGAATCGGCCGCGTCCGCCGAATCCTTATTTTGCGCCATATCCAGGAGCGCCCCCGCCGCCAGCGTTTCGATATAGATTTCCACCAGCGATTCGGCCACACTCAAGATATAGCTATAGAAAtgatcggcagcagcagcagcagcacccatcggggccaaaataa
Protein Sequence: METAMCRICLNTTVTLVEIFAKREQSDKANPEPSLADMLNECADCHIKSNDSLPQQICLSCVLCAQNAFSFKRKCEQSYQQLVAKRKLRQEIAAKETTSKTVPIKKELLDGLDIKQEHEIKVEPASSESPLYKCPYCCKKFTHLRILSLHKKWHAENQHSNRRVGPKPSKVESKSKICSICKKKCKSVSLLRKHLWSHSDLRPFPCTLCPTSFQFNSHLKRHMRSHTGERPYQCPFCPEAFSRSDYCRAHMDKMHSGLTFTGKLMRRSRDRGRAKKREKEKLPYFADVGRERDRMRNLRQHHRTERSLTPPPQRRPRLRSRSHSPQTNYRQRRRSRSAERSHRTSRNMRHASPYAHRRRSRSRSRTPRIITVPVPVPAAGYPYAYDWPRQPNFHAMFAPMPFAMNRPRPPNPYFAPYPGAPPPPAFRYRFPPAIRPHSRYSYRNDRQQQQQHPSGPK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00616485; iTF_00549160; iTF_00522521; iTF_00559118;
90% Identity: iTF_00559118;
80% Identity: -