Basic Information

Insect: Drosophila cognata
Gene Symbol: -
Assembly: GCA_035041535.1
Location: JAWNLC010000241.1:16011034-16013126[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.0047 0.3 11.6 0.4 3 23 428 449 426 449 0.94

2 6 0.24 15 6.3 1.5 1 23 456 479 456 479 0.91

3 6 0.00017 0.011 16.2 0.7 2 23 485 506 484 506 0.97

4 6 0.00024 0.016 15.7 0.3 1 23 512 535 512 535 0.94

5 6 0.00033 0.021 15.3 0.5 1 23 541 563 541 563 0.97

6 6 0.00091 0.058 13.9 3.0 2 23 570 592 569 592 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.0047	0.3	11.6	0.4	3	23	428	449	426	449	0.94
2	6	0.24	15	6.3	1.5	1	23	456	479	456	479	0.91
3	6	0.00017	0.011	16.2	0.7	2	23	485	506	484	506	0.97
4	6	0.00024	0.016	15.7	0.3	1	23	512	535	512	535	0.94
5	6	0.00033	0.021	15.3	0.5	1	23	541	563	541	563	0.97
6	6	0.00091	0.058	13.9	3.0	2	23	570	592	569	592	0.97

Sequence Information

Coding Sequence: atggaaatatgcGCCAACGTATTAACCAATACCAACTACACAGAATTTCACTTGAAGTGCATATATTGTTCGATCGAAAGTGATCTGAAAGACTGGGAACAGTTCGTGTTGCATACGCGCAATGATCATCTTCTGGATGATGCAGATGAAGGAAGTGCCCAAGGTGAAAATGAAAGCTTATATGCCCGTGAGGAGAATTTTGAGGCTTACGAAGACACTGACAACAGCGTCAGTGACTTTAAAGATGATTACGAACAGTTCCCTACCGACGATCTGAATATTGAAGAGCCCAATGAGTTCATTATGgacaattttgttttacaatCACCAAATGAAACGATAGCACTTGCCTCACATAGttataatgatatatattctatatcaGAAACAATTGAACAAGACATTTCTGGCGATGAGAATGAAAATCGGATGATAGAGGCTACAACAATTACTCAGGATCATTATCCGTCAGATGGCAAATATAATGATGCCGAGGAATGGGCCAGCTCCACTGACTCTGATGACGAACAACGGGCGCATCAGCCCAAACGTAGTCGAAGTTCAACAATAATGCGCAAGTTACATGTGTCTTTCAAACGCCACAATCCCCGTCTGCTACATTTCATCGAAGAATTCAAGAAGCAGACATGCTTGTGGAACCCAAATGATTCAAAATTCGGCGATAAGAAATTCGAAACTGAGGCCTACACTTCAATGATTGAAGGCATGGCCAAAAAAGCCGATGTGCTTCTCACAAAAATAGAACTGAAGAAGTCCATACAGCAATTGCTTAGCCAATTCGCCTTAGCCAGCCAAAGGGATGAGTATAAGTCGCTGACTGGAATGCATGCAAGTTACTTTCGTAAATGTAAATTCCTTTCGATCGCACCTGACCATTCACAAAGTAATAGCGACGACAACGCTAATAATGTCCATTCGGACGTAATACAGctAAATTTCAAGGAGATCAACAAAATGACGACCACTTTTATTGAGATCTTCGAAAACTTTCCGGAGCTCTATGACAGCTCAGTAGCGGAGTTTAAATCCCTCGAAGCACGCACACAGGCATACATTAAGATAGCCGAGTTGCTGGAACCGGAGATGCGAGTTAACGAAACTGAAGTTCATTTAGCCACCGTTCGATTACGTAAATGGGCCTATATGACACTGCGGCGCGTTAAATCGAAGGAATTACGACGCGCCTGCTCCAAAACAGAACTGCATTATATACAACAGTGCAGCTTCCTGCCGCCAAAATCGGAAAGCTTCGTCATAAATTGTGAATTATGTGACAAGCGTTTCTTCATCGACTACAGTCTCCGCACGCATATGGTCAAGGTGCATAATGTGGGCGAACTGCCATATCTGTGCTCCCAGTGCCCGCGTCGATTTGGCATATATCACGAAATGGAGCGGCACAACTTGCGGCAGCACTGTGAAAAGATGCTCAAGTGTGGATACTGTGATAGCACATTTTCACTGAAGAACGACCTCAATCTGCACACACGTGTCCACACGGGGGAGAAACCGTTTGTGTGCGAGATGTGCGGCAAATCCTTCCGACTCAGACTGCTGCTGGTATACCACATAAATGGGTTTCATCTGAACCTGCGGCCATTTGCATGTGATCTCTGTCCCAACACTTATCAAAGGAGGGTTCAGTTGAAAAACCATATGAAAGCCCATTTCAATATCAAGGATAAGAAATGCAACGAGTGTGGAGCATCATTCACCTGTCCGACCAGCCTTTCCCGTCATCGCAAGACATTACATAACACTCCAAAACCTAAGACCCGGACTAACATTTTATAA
Protein Sequence: MEICANVLTNTNYTEFHLKCIYCSIESDLKDWEQFVLHTRNDHLLDDADEGSAQGENESLYAREENFEAYEDTDNSVSDFKDDYEQFPTDDLNIEEPNEFIMDNFVLQSPNETIALASHSYNDIYSISETIEQDISGDENENRMIEATTITQDHYPSDGKYNDAEEWASSTDSDDEQRAHQPKRSRSSTIMRKLHVSFKRHNPRLLHFIEEFKKQTCLWNPNDSKFGDKKFETEAYTSMIEGMAKKADVLLTKIELKKSIQQLLSQFALASQRDEYKSLTGMHASYFRKCKFLSIAPDHSQSNSDDNANNVHSDVIQLNFKEINKMTTTFIEIFENFPELYDSSVAEFKSLEARTQAYIKIAELLEPEMRVNETEVHLATVRLRKWAYMTLRRVKSKELRRACSKTELHYIQQCSFLPPKSESFVINCELCDKRFFIDYSLRTHMVKVHNVGELPYLCSQCPRRFGIYHEMERHNLRQHCEKMLKCGYCDSTFSLKNDLNLHTRVHTGEKPFVCEMCGKSFRLRLLLVYHINGFHLNLRPFACDLCPNTYQRRVQLKNHMKAHFNIKDKKCNECGASFTCPTSLSRHRKTLHNTPKPKTRTNIL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00549110;
90% Identity: iTF_00560606;
80% Identity: -