Basic Information

Insect: Drosophila cognata
Gene Symbol: -
Assembly: GCA_035041535.1
Location: JAWNLC010000590.1:468419-471381[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.0039 0.25 11.9 1.6 3 23 152 172 150 172 0.96

2 7 0.0051 0.32 11.5 0.7 1 21 178 198 178 199 0.95

3 7 0.016 1 9.9 2.3 2 23 536 558 535 558 0.94

4 7 1.5e-05 0.00095 19.5 2.0 1 23 650 672 650 672 0.98

5 7 4.6e-05 0.0029 18.0 5.7 1 23 678 700 678 700 0.98

6 7 0.0004 0.025 15.0 2.9 1 23 706 728 706 728 0.98

7 7 0.00039 0.025 15.0 0.1 1 21 734 754 734 755 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.0039	0.25	11.9	1.6	3	23	152	172	150	172	0.96
2	7	0.0051	0.32	11.5	0.7	1	21	178	198	178	199	0.95
3	7	0.016	1	9.9	2.3	2	23	536	558	535	558	0.94
4	7	1.5e-05	0.00095	19.5	2.0	1	23	650	672	650	672	0.98
5	7	4.6e-05	0.0029	18.0	5.7	1	23	678	700	678	700	0.98
6	7	0.0004	0.025	15.0	2.9	1	23	706	728	706	728	0.98
7	7	0.00039	0.025	15.0	0.1	1	21	734	754	734	755	0.96

Sequence Information

Coding Sequence: ATGCACGAGGAAATTGTGATTAAAACTGAGGAAATTGATATTGATGATACAAAGATAAAGCTTGAGGTCGATGAGGATGGGCCAACATTGGAATTTTCGTGcgCTGGCACCTTTATGAAAATAATCGAGGAGCGGCCGAATATGATAACGGTGCCGGTTCACGACTGCAAATCTGAGGACGAACTCAAATTCATAGCGAGCCTCGGCACTTTCGATCAGCAGCAAAAGTTATTTGTGACGTCATCGGCTGAGAGTGCTTCCTCTCTTGGCGCATTTGTATGCAAAGTATGCAGCTTTACGTGCGAAAATCACTTATCGCATGCTTCGCATCAGAACAACCATCAGCTAAATCGCCATTTCTGTTGCCATGGCTGTGGCGAGTGGTGTAACACGCTCGAAGAAATCCAGGAGCATGAATATCGGAAGCACGCGGATGGAGTTAACAACTCCAACTGCAGGATCTGTCAGTTCGAGTGTACCGATGCAGCCAGTCTGTCGAGGCACATGAGCAGTCACTTCTATGTGCGTCGCTTTGTGTGCTCCATTTGTCGCCGGCATTTTGAGACACGCCTGGAATTGCAACTGCATCGGCAGGACGGCAATAAGCTGTGCGGTCAGCTCGAATATGCTGATATGCATGGAAATATCGGTCAGCTGGTGGCGATCAGTAAATTGGATACGACACTGCCAGCTGAGCGGTTCTGTGACATAGAAATTAAATCTGAGCCGATGGACGTAGATGATCAGCTTCCACCTGGTATTATTATCAAAACGGAGCCACAGTCGCAAGCAGCTGAGTTAAATTCCACTGGCCATGACAGCTGGACCCGAAACAGCCTAGCAGGACAATTACGCAGCAAATTGCGCTTGCCCATAATAAAGAAACCGCAGAAAGAGGAATGTGTAGTGCAGGAGAAACCAAGAGCGCCTTTGAATAAATCACACTTTGTGCCCACTGGTAAACTCATACCTTTTGCAACCTCTACAGCATCACAGAATCACTCCAACATTTTATGGCCAAAGCAATCAGACAAGCAGACCTCAAGTATTTTGAAGAAGAACATTTCCAAAcccaatacaaatatttccgCCAACGTCGTAAAGCTAATGCAAAGTAATTGCATGGTGATTAAAGTGCTGCCAAACATGAAGGTAATAAAGCTGGCACCCACCGCAACGGGTAACACTACGAATAGCTTCGATATAGGAGGGAAAATAATCACATTGCCAAGCTCCATGTCGATAAGTTCGGGACATCAAAGCTCGACGGCTGGCCAAACGGACACTATTCCAACCCCATCTGCTCCCACTTCGCTACAAGCGGCCTCACTGACATTGCCCACTAATCGAAATTCCCATTTGAATGCTATTAGTTTGTTTGAGAGTTTGCCAGAGTCTCGCAAGATCATCACAGATATCCAGAATCAGATACGCAACATAGAGCAAAAGCTGCCACTGCCCGGCAGTGTGCTGCAACCGAAAAACAGAAGCACCAAGGTTGAGTTGCCTGCGCAGCTTCAGATGCTTCGACTGCCGCTCACCAAGGAGAGTAATCTGAAGGTACGTCAATTGCGCAACGCATATCCTGATCATCGCTTTCACTGGGAATGTCCGAACTGTGCGCGCTGTTTCGAACAATTTGCGGCATTCTGCAAACACTTGACAGTCTCGCACGACATCACAGAGGCAAAGTTTGAGGACATGTCAGTGGAGGTCAAGTCTTATAAGAAATGTATTTCGTTGATTCCCACAACTGTAGGAGCGACAGTTCCTGTAGTGCCAGATATAACAAATACGCCTCCATTAAATTCTTCTGCTGATCCAGATCCTGTGCAGGATGAAGAGGCAGCTGCTCCACCAACTGTGGCACCTGAAATTACAGATCCTGAGCCAATCTTACCGACCCCAGCGTCTACTAGTGTAACCCCCCAATCTTGGTATTCTCAATATAAATGCGACGATTGCTCAAAGTGCTTTACCACTATGGGTGGGCTACGCATCCACAAGATGATTCACACCGGTGAGCTGCCACATAAATGCAACTACTGTGAGAAGCGTTTCCGCACTCCTGGCCAGGTGCGTGTCCATCATCGCAGGCACACTGGCGAGAAACCATTCAAATGCAAGGTGTGCTCACTGGATTTCACACATCGCGAAACGCTCATCTCGCATCTCTCGCGTCACATTGGCATGAAGCGCTACAAGTGCTACGGCTGCGATAAGAACTTTATTGTTGTCAGTGGATTACGTGCCCATCGCCGTTTACGTCCTGACACGTGCGGCAAGGTCAAGTTTACGGCTCGCGCCCATGGGCCGCGAGTTCGCGTAATACGCGGCGAAGTCGTCTTCGAATCCCATCCTGAGCACAATGGCTACTTGCGCAGCGAGGACCCTTTAAACATAATGTCTGAGATGATTCATGCCAAAGAACCGTCTGTGGCCAATGAGTCCAGCTAA
Protein Sequence: MHEEIVIKTEEIDIDDTKIKLEVDEDGPTLEFSCAGTFMKIIEERPNMITVPVHDCKSEDELKFIASLGTFDQQQKLFVTSSAESASSLGAFVCKVCSFTCENHLSHASHQNNHQLNRHFCCHGCGEWCNTLEEIQEHEYRKHADGVNNSNCRICQFECTDAASLSRHMSSHFYVRRFVCSICRRHFETRLELQLHRQDGNKLCGQLEYADMHGNIGQLVAISKLDTTLPAERFCDIEIKSEPMDVDDQLPPGIIIKTEPQSQAAELNSTGHDSWTRNSLAGQLRSKLRLPIIKKPQKEECVVQEKPRAPLNKSHFVPTGKLIPFATSTASQNHSNILWPKQSDKQTSSILKKNISKPNTNISANVVKLMQSNCMVIKVLPNMKVIKLAPTATGNTTNSFDIGGKIITLPSSMSISSGHQSSTAGQTDTIPTPSAPTSLQAASLTLPTNRNSHLNAISLFESLPESRKIITDIQNQIRNIEQKLPLPGSVLQPKNRSTKVELPAQLQMLRLPLTKESNLKVRQLRNAYPDHRFHWECPNCARCFEQFAAFCKHLTVSHDITEAKFEDMSVEVKSYKKCISLIPTTVGATVPVVPDITNTPPLNSSADPDPVQDEEAAAPPTVAPEITDPEPILPTPASTSVTPQSWYSQYKCDDCSKCFTTMGGLRIHKMIHTGELPHKCNYCEKRFRTPGQVRVHHRRHTGEKPFKCKVCSLDFTHRETLISHLSRHIGMKRYKCYGCDKNFIVVSGLRAHRRLRPDTCGKVKFTARAHGPRVRVIRGEVVFESHPEHNGYLRSEDPLNIMSEMIHAKEPSVANESS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00620147;
90% Identity: iTF_00497693;
80% Identity: -