Basic Information

Insect: Drosophila cognata
Gene Symbol: grau
Assembly: GCA_035041535.1
Location: JAWNLC010000241.1:2047595-2050070[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.075 4.8 7.8 1.1 6 23 450 467 450 467 0.98

2 8 0.00026 0.017 15.6 2.8 1 23 473 496 473 496 0.93

3 8 0.002 0.13 12.8 1.0 1 23 504 526 504 526 0.97

4 8 3.9e-05 0.0025 18.2 1.0 2 23 532 554 531 554 0.96

5 8 0.08 5.1 7.8 0.0 2 23 560 581 559 581 0.96

6 8 0.00075 0.048 14.1 0.5 2 23 619 641 618 641 0.94

7 8 1.9e-05 0.0012 19.2 0.4 3 23 649 669 648 669 0.99

8 8 0.00039 0.025 15.0 8.7 1 23 675 698 675 698 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.075	4.8	7.8	1.1	6	23	450	467	450	467	0.98
2	8	0.00026	0.017	15.6	2.8	1	23	473	496	473	496	0.93
3	8	0.002	0.13	12.8	1.0	1	23	504	526	504	526	0.97
4	8	3.9e-05	0.0025	18.2	1.0	2	23	532	554	531	554	0.96
5	8	0.08	5.1	7.8	0.0	2	23	560	581	559	581	0.96
6	8	0.00075	0.048	14.1	0.5	2	23	619	641	618	641	0.94
7	8	1.9e-05	0.0012	19.2	0.4	3	23	649	669	648	669	0.99
8	8	0.00039	0.025	15.0	8.7	1	23	675	698	675	698	0.98

Sequence Information

Coding Sequence: ATGATTTGCCGTCTGTGCCTGAACAGCGTCAACGACaccatacaaatatttgaaggaGTCGGCCTAGCGCTGAACATTGCCACAGTGCTGGCTAAATACTTTTGGTTTCAGCCGAAAAGCGATGATCTCATATCGACGGCCGTTTGTAGGGGCTGCTGGACCCGGGTCAGTGACTTTAACGAGTTCTATGCGAGCGTGGAAGAGGCGCATCGCCTCCTCACCGAACGTTTCTCCATTAAAGGcggcgaacagcagcagctgaagcccCATTCAAATATCCAGAGTTTGCTGTTCGGTGAGTTCAAGGAGGCGATAGAAATGCAGGAGGACTCAAAAGATTTCCTTTAtaatgatgaggatgatgactTGGATCAAGATCAGGATCGGGACACGATTGTCGAGGATTTGTATGTCAGCGGCAACGAGAGTGATACAGCTGCATCGTTCAGCAACGAACAGCTCCTCAACGATGTGCTTTCCCAGCAGGCACAACCAAAAGAAGAAGTGCCCGATGAACCAGAACCAGAGCAAACAGCTGCTGAACTGCACTCAACTGAAGCCGCTCAGGAGCGTCGTAAAACTCGTTCCACGCGTGCGAAGAGCAAAGCGCATCAGGAAAATGAATCGCTTCCAGCTGAAAAGAAGACACTAGCCAAGCAACGAAGCAGATCAAAAACGGAGAAAGTCGTTGCCAGCGATGCGGAGGAGTTGCCGAAGCACAAACGTTATGTGGACTACAAGCAATCCATGCTGGAGATTGATGAAAAGAAGGAGGCGATAGAAATGCAGGAGGACTCAAAATATTTCCTTCATCATAATGAGGATGATGTCTTGGATCAAGATCAGGATCAGGACACGATTGTCGAGGATTTGTATGTCAGCGGCAACGAGAGTGATGCAGGTGCATCGTTCAGCAACGGACAGTTCCTCAACGATGTGCTTGCCCAGCAGGCACAACCAAAAGAAGAAGTGCCCGATGAACCAGAACCAGAGCAAACAGCTGCTGAACTGCAGTCAACTGAAGCCGCTCAGGAGCGTCGTGAAACGCGCTCCACGCGTGCAAAGAGCAAAGCGCATCAGGAAAATGAATCGCTCCCAGCTGAAAAGAAGACACTAGCCAAGCGAGGAGGCAGACCAAAAAAGGAGAAATTCGTTGCCAGCGATGCGGAGGAGTTGCCCAAGCACAAACGTTATGTGGACTACAAGAAATCTATGCTGGAGATTGATGAGAAGATCGCCCAACATATGCGCCTGACTTGCAGCGTCTGCCATGTGGGACAGGAGACGTTCCGGAAGCTGTGCAAGCACATGATGCAGATGCATCATCGCAAAGGGTATGCGGTCTGCTGCAATAGGAAATTCTACAAGCGTTCCTTTCTCACCGATCACATCGACCGCCACTCAAATCCCGAGAAATTTAAATGCGATCTGTGCGATCGAACCTTTGCGGACAAGCAATGCCTCCGCAGTCACGAGCTGCTCAAGCACCAGCCGGACGAGCAAAAGAAGTTCATGTGCGAGCACTGTCCCATGCGCTATGCCAAGCAGTATCTATTGGATCAGCATCGCATCATACACATGGAGCGCAACGTGCCCTGCAACATCTGCGACAAACGTTTTCCCAATGTTTCAAAACTGTGCACGCACGTGAAAAGGGTGCATGGCAATTATGGCACCATGTGCGACATTTGCGCACAGGTTATTCGAGGAGCGGCTGCATTTGAGCGCCATCAGTTGACGCACGCTGGGATTACGGAGCCAAAGGTGCAGTGCGAGATATGTGGTTCGTGgcacaagaacaagaacagtTTGAAGTATCACGTGCGTTTGCACAACGCCTCCTCGGAGGAATGTAAGTGCAATATCTGCGGCAAGGTGTCGCCGAATCGCGCCGCCATGCTCAGCCATCAGAACTATGTGCACAATACGAATCGGGTGCATGGCTGCagtgtgtgcaacaaaaaatttaagaGGGCCATTAGTCTGAAAGAGCACATCGCCACGCATACAGGCGAGGTGCTCTACAAGTGTGAGCACTGCCCGAAGACCTTCAATTCGAATGCCAACATGCATTCGCATCGCAAAAAGTGCCATCCCAAGGAGTTCGAGGAGTCGCGCAAGGCACGCATACAGAAGCGCATGGGATGA
Protein Sequence: MICRLCLNSVNDTIQIFEGVGLALNIATVLAKYFWFQPKSDDLISTAVCRGCWTRVSDFNEFYASVEEAHRLLTERFSIKGGEQQQLKPHSNIQSLLFGEFKEAIEMQEDSKDFLYNDEDDDLDQDQDRDTIVEDLYVSGNESDTAASFSNEQLLNDVLSQQAQPKEEVPDEPEPEQTAAELHSTEAAQERRKTRSTRAKSKAHQENESLPAEKKTLAKQRSRSKTEKVVASDAEELPKHKRYVDYKQSMLEIDEKKEAIEMQEDSKYFLHHNEDDVLDQDQDQDTIVEDLYVSGNESDAGASFSNGQFLNDVLAQQAQPKEEVPDEPEPEQTAAELQSTEAAQERRETRSTRAKSKAHQENESLPAEKKTLAKRGGRPKKEKFVASDAEELPKHKRYVDYKKSMLEIDEKIAQHMRLTCSVCHVGQETFRKLCKHMMQMHHRKGYAVCCNRKFYKRSFLTDHIDRHSNPEKFKCDLCDRTFADKQCLRSHELLKHQPDEQKKFMCEHCPMRYAKQYLLDQHRIIHMERNVPCNICDKRFPNVSKLCTHVKRVHGNYGTMCDICAQVIRGAAAFERHQLTHAGITEPKVQCEICGSWHKNKNSLKYHVRLHNASSEECKCNICGKVSPNRAAMLSHQNYVHNTNRVHGCSVCNKKFKRAISLKEHIATHTGEVLYKCEHCPKTFNSNANMHSHRKKCHPKEFEESRKARIQKRMG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00607341; iTF_00607348; iTF_00620129; iTF_00620145; iTF_00607387; iTF_00495433; iTF_00495432; iTF_00495413; iTF_00620159;
90% Identity: iTF_00495433; iTF_00495432; iTF_00495413; iTF_00620129; iTF_00620145; iTF_00607387; iTF_00607341; iTF_00607348; iTF_00620159;
80% Identity: -