Basic Information

Insect: Drosophila cognata
Gene Symbol: -
Assembly: GCA_035041535.1
Location: JAWNLC010000241.1:14596736-14598948[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 2.8 1.8e+02 2.9 2.3 1 19 141 159 141 161 0.90

2 10 0.004 0.26 11.8 4.8 3 23 208 228 206 228 0.97

3 10 0.00052 0.033 14.6 1.5 1 23 254 275 254 275 0.97

4 10 0.00059 0.038 14.5 1.7 1 23 281 303 281 303 0.95

5 10 0.00017 0.011 16.1 0.3 1 23 332 354 332 354 0.97

6 10 9e-08 5.7e-06 26.5 0.9 1 23 360 382 360 382 0.99

7 10 0.0026 0.17 12.4 6.6 1 23 388 410 388 410 0.98

8 10 7.7e-06 0.00049 20.4 0.7 1 23 416 438 416 438 0.98

9 10 3.3e-05 0.0021 18.4 0.2 1 23 442 464 442 464 0.99

10 10 0.0024 0.15 12.6 0.0 3 23 488 509 486 509 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	2.8	1.8e+02	2.9	2.3	1	19	141	159	141	161	0.90
2	10	0.004	0.26	11.8	4.8	3	23	208	228	206	228	0.97
3	10	0.00052	0.033	14.6	1.5	1	23	254	275	254	275	0.97
4	10	0.00059	0.038	14.5	1.7	1	23	281	303	281	303	0.95
5	10	0.00017	0.011	16.1	0.3	1	23	332	354	332	354	0.97
6	10	9e-08	5.7e-06	26.5	0.9	1	23	360	382	360	382	0.99
7	10	0.0026	0.17	12.4	6.6	1	23	388	410	388	410	0.98
8	10	7.7e-06	0.00049	20.4	0.7	1	23	416	438	416	438	0.98
9	10	3.3e-05	0.0021	18.4	0.2	1	23	442	464	442	464	0.99
10	10	0.0024	0.15	12.6	0.0	3	23	488	509	486	509	0.96

Sequence Information

Coding Sequence: ATGTCAGCACACAGTGGAATAAAGGCTGATGCGTCAACAACAGCGGTGCAATCGCACGTGGATgtcaaaagccaaaacaataTTGATCATTTTATAATTGATACGTGTGCGGATGAACTATATTACTGTGTGGATTGTGGCAATGACTACGACAGCATCGAGGCGTacaacaatgcgcacagtggCCTCGACAGCTGCACAGGCGccatgaaaaatgaaatgaacggCGAAGATGATCGAGTGGATGTTGAATCCATTATCCTCGAGGATGATCTAATTGAGGAAGTCGACGATGGAAGTGAACCCCATCTCTGGGAGGTGCTCGATGTGGATGAGGAACTGCGGCCAGCCGAAGTCGAGGACGAGGCGcaagctgaagctgaggctgaggcagaGCAAATATCCACCAAGTCAGAACGTTACTTTTGCTTCGATTGCCACAACATATTCGTGACACGTGAGAGTGCCGAGGAGCACAGCTGCCCCCAggcagaggcaacaacaacaactacaaccgGTGGCAAACAGAGCAATGCCAACAAGTTGGCCAAAACGCAGACACCAGCGCGACGcaaagtggcaacagcaacagcaacgagtaGCAATAATACGGCCActatttgccacatttgcaaAACCGAATTCAGTTCGCCCAAATGCCTCAAGTTTCACATGCGCATCCACAACAAGCTTGCTCCCAAATCCATACAGGATGCTTTGCCTGTTGGCGCACATCAGCAGTACAGCGAGCTGGATCAATTCTACTGCGAAATCTGCAACAAGAGCTTCGAAAAAAACCTGTTAACGGTGCACAAACAGATGCATCAGAGCCATAAACAGTTTCTGTGCGGCACTTGCAACCGCAAATTCGAAAATCTAACCAACTATAAAATGCATCTCAAGATCCATGAACGTCACGCATTAAATAagagtagcaacaacaacaacaaacccaTTAAAAGGCCCTCCAATGTGGCCAAGGATAAGCCAGGATTCGCCTGCCAGTACTGCGAGCGGGTTTTCCCGCGTCCCTACGAGAAGGTGAAGCACGAGCGTGTGCACACCGGCGAGAAGCCCTACAGCTGTGAGGTGTGCGGCAAAACCTTTCGTGTCTCCTACTCCCTCACGCTCCACCTGCGCACGCATACAAACATACGGCCGTATGTGTGCACCACGTGCAACAAGCGCTTCAAGTCGCATACGGTTTACTCGCACCATTTGCGCATTCATAGCTCGGAGCGTCAGTATGTTTGTGATAGCTGTCCGAAATCCTTTCGCACATCCGTGCAGCTTTACGCGCACAAGAATAGTCACACCAAACCGTATCAGTGCGCAGTCTGCAATCGTCCTTTCGCCTCACTGTACGCTGTCAAGTCACACATGTCCACCCACAAAACGAGCGATGCGAAGGGCGCCAGCAACCAGGTCACCAGGAGCCAACACATGTCCAATAAATATTGGTGTGTTACCTGCGGAGCAGAGTATGCGCGTCCCTTTGCGCTCCGCCTGCACATGAAGTCTGCCCACGGGCATCAAGATGATGCGGATACACGCTTTGCAAAGATCGCACCAACAGATGACGATGAGATTACTGTGGCCGATACGGAGACGGCGGTGCTCATAGCAGCGGCAAAGGCGGATTCAGCGTATCTATGCGCTAATGCCAATGAAGTGGATATTATGAGTGCCGTGTCCAAATACGAAGAATGCATTGAAGAATCAACAGATGCGTTCGATGTGGAAACCTTCCATAACGAGGAGATCATCACCGACTGGCTAAAGTAG
Protein Sequence: MSAHSGIKADASTTAVQSHVDVKSQNNIDHFIIDTCADELYYCVDCGNDYDSIEAYNNAHSGLDSCTGAMKNEMNGEDDRVDVESIILEDDLIEEVDDGSEPHLWEVLDVDEELRPAEVEDEAQAEAEAEAEQISTKSERYFCFDCHNIFVTRESAEEHSCPQAEATTTTTTGGKQSNANKLAKTQTPARRKVATATATSSNNTATICHICKTEFSSPKCLKFHMRIHNKLAPKSIQDALPVGAHQQYSELDQFYCEICNKSFEKNLLTVHKQMHQSHKQFLCGTCNRKFENLTNYKMHLKIHERHALNKSSNNNNKPIKRPSNVAKDKPGFACQYCERVFPRPYEKVKHERVHTGEKPYSCEVCGKTFRVSYSLTLHLRTHTNIRPYVCTTCNKRFKSHTVYSHHLRIHSSERQYVCDSCPKSFRTSVQLYAHKNSHTKPYQCAVCNRPFASLYAVKSHMSTHKTSDAKGASNQVTRSQHMSNKYWCVTCGAEYARPFALRLHMKSAHGHQDDADTRFAKIAPTDDDEITVADTETAVLIAAAKADSAYLCANANEVDIMSAVSKYEECIEESTDAFDVETFHNEEIITDWLK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00500492;
90% Identity: iTF_00560475;
80% Identity: -