Basic Information

Insect: Drosophila cognata
Gene Symbol: -
Assembly: GCA_035041535.1
Location: JAWNLC010000150.1:869263-873806[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 25 0.00055 0.035 14.6 0.9 1 23 214 236 214 236 0.97

2 25 0.00065 0.041 14.3 2.8 2 23 243 264 242 264 0.97

3 25 0.012 0.75 10.4 0.9 2 23 297 318 296 318 0.96

4 25 0.00064 0.041 14.4 0.7 1 23 393 416 393 416 0.94

5 25 0.38 24 5.6 0.6 2 22 426 446 426 446 0.96

6 25 3.1 2e+02 2.7 0.4 1 20 455 474 455 476 0.91

7 25 0.0048 0.31 11.6 0.5 1 23 597 620 597 620 0.96

8 25 0.0093 0.59 10.7 0.1 1 22 629 650 629 650 0.95

9 25 0.0033 0.21 12.1 4.3 1 23 659 682 659 682 0.97

10 25 6.8e-05 0.0043 17.4 0.4 2 23 696 717 695 717 0.97

11 25 2.2e-05 0.0014 19.0 5.4 1 23 723 745 723 745 0.98

12 25 0.076 4.8 7.8 0.5 1 23 885 908 885 908 0.95

13 25 0.03 1.9 9.1 2.2 1 22 915 936 915 936 0.95

14 25 0.43 27 5.5 0.4 1 20 945 964 945 968 0.86

15 25 6.2e-05 0.0039 17.5 1.6 1 23 992 1014 992 1014 0.97

16 25 0.00047 0.03 14.8 0.7 1 23 1021 1043 1021 1043 0.98

17 25 0.13 8.1 7.1 0.0 2 21 1070 1089 1069 1090 0.94

18 25 0.041 2.6 8.7 4.0 1 23 1135 1158 1135 1158 0.96

19 25 0.007 0.45 11.1 1.5 1 23 1195 1218 1195 1218 0.96

20 25 0.015 0.95 10.1 3.1 1 23 1245 1268 1245 1268 0.97

21 25 1.4e-05 0.0009 19.6 0.1 2 23 1289 1310 1288 1310 0.95

22 25 4.8e-05 0.0031 17.9 2.9 1 23 1316 1338 1316 1338 0.99

23 25 4.4e-06 0.00028 21.2 2.3 1 23 1344 1366 1344 1366 0.97

24 25 3e-07 1.9e-05 24.8 2.6 1 23 1372 1394 1372 1394 0.99

25 25 0.00052 0.033 14.6 0.3 1 22 1400 1421 1400 1424 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	25	0.00055	0.035	14.6	0.9	1	23	214	236	214	236	0.97
2	25	0.00065	0.041	14.3	2.8	2	23	243	264	242	264	0.97
3	25	0.012	0.75	10.4	0.9	2	23	297	318	296	318	0.96
4	25	0.00064	0.041	14.4	0.7	1	23	393	416	393	416	0.94
5	25	0.38	24	5.6	0.6	2	22	426	446	426	446	0.96
6	25	3.1	2e+02	2.7	0.4	1	20	455	474	455	476	0.91
7	25	0.0048	0.31	11.6	0.5	1	23	597	620	597	620	0.96
8	25	0.0093	0.59	10.7	0.1	1	22	629	650	629	650	0.95
9	25	0.0033	0.21	12.1	4.3	1	23	659	682	659	682	0.97
10	25	6.8e-05	0.0043	17.4	0.4	2	23	696	717	695	717	0.97
11	25	2.2e-05	0.0014	19.0	5.4	1	23	723	745	723	745	0.98
12	25	0.076	4.8	7.8	0.5	1	23	885	908	885	908	0.95
13	25	0.03	1.9	9.1	2.2	1	22	915	936	915	936	0.95
14	25	0.43	27	5.5	0.4	1	20	945	964	945	968	0.86
15	25	6.2e-05	0.0039	17.5	1.6	1	23	992	1014	992	1014	0.97
16	25	0.00047	0.03	14.8	0.7	1	23	1021	1043	1021	1043	0.98
17	25	0.13	8.1	7.1	0.0	2	21	1070	1089	1069	1090	0.94
18	25	0.041	2.6	8.7	4.0	1	23	1135	1158	1135	1158	0.96
19	25	0.007	0.45	11.1	1.5	1	23	1195	1218	1195	1218	0.96
20	25	0.015	0.95	10.1	3.1	1	23	1245	1268	1245	1268	0.97
21	25	1.4e-05	0.0009	19.6	0.1	2	23	1289	1310	1288	1310	0.95
22	25	4.8e-05	0.0031	17.9	2.9	1	23	1316	1338	1316	1338	0.99
23	25	4.4e-06	0.00028	21.2	2.3	1	23	1344	1366	1344	1366	0.97
24	25	3e-07	1.9e-05	24.8	2.6	1	23	1372	1394	1372	1394	0.99
25	25	0.00052	0.033	14.6	0.3	1	22	1400	1421	1400	1424	0.91

Sequence Information

Coding Sequence: atgttgcCGACGAATGTTTGTCGCACGTGTGCGCTGCAAGATGACAACTTGTTGGCGCTGGCAACACGTAGTGAGAAATACGCAAAGAAAAGTATCTGCGACATGCTGCATGAATTAACACAAAACGATCCACTACTGGAGCATACAGATGATAAGCTACCGCAGCATTTGTGCGGCCAATGCTTGAGCCAGCTGGAAGCAGCCTATGCATTTGTGCTGCAAGCCCGCGAGGCGCaggagcaactgttgctgcagctacGCAAAGGATTGCAGACACAGTGCCTGGACGAAACACCTATCGATATAAGCATAGAACACATCAAAATCGAAACAGACATTGACCTAGATGCGGACACGGCTGATGCAGTTGATGCTGAGTttgaggaggagcaggagaagcATGTTGTCTTAAAATGTCAGCCGGAAAGTGATAGCGATAGCAGTCAGGATAATGTGAAGGACCATGACGTTGAGGTCCAAACCCTGCAGCTGCGGCGCAGTGCTCGACGAGCCAAACTGAGCACAGACAGCGAAAATGAGTCAATCTCCGAGCAGGTGAAGCCGTTGCCTGTTAAGCGTGGACGCGGTCGTCCCCGACGTGTGGCCAAGAGGGAGACGACCACCAACGAGGATGGGCGGCATGTGTGCGAGGTGTGCGGCAAGACCTTCTCCTGGTATCGCGACATGCAGCGCCATGCACGCATCCACTTCGAGCAGGCGGGCATTGTGTGCGAGCACTGCGGCAAGAAGTTCCTGCGCAAGGATAAGTACATGACCCATCTGCGATCACACAAAAAGCACGTGgccacagacagacagatactGCCACGGAGCAGCGAGTGGCGCTACGCGGAGCGTCTATACAGTTCCGGCAGATTAATGCGTGTGGAGTGCAAACTGTGCGGATTGAGTTGCCAGCGCATTCGGGAGTTGCGCAACCACCTGGCGAGTCATGTTCACATTGAGACATTGTGGAATCTCAGTCTGGACAACGATGTCATCCGGGAGCAATTTGGCAGCCAATCGGATTTGGAGCAAATCAAGGAACAGGTCTGCACGCAAATTGCCAAAGGTCGCGAACAACTGGAGAATTACGGCGCCGTGGTGAATGCCTACGGTTATGAGTTGTGCCTCAGCGACtcggatgaggaggaggatgaggagctgTCTGGCAAATATCAGTGTCTGCGCTGCAATGTCAACTTTGCACGCAAGTATCAACTCGTGCGTCACACGCTCGAGGAGCACACGGACAGAAGTGAAACTCCTTTGGAACGCTGCAATGTCTGTCAAATTGGCTTTGTTTGCGCCAAGCTGCTGGAGCAGCATCAGCGCACGCAGTGCCTCAATCCGCTGAAGCGTTACAGCTGCGAGAATTGTCCTGGCAAGTTTATTTGGCTGCAGAATCTGCAGCAGCATGCATGCAGCAGGCTGCAACATGATCTTCAGCAGGAACTGCAGCATCGGcatcaggagcagcagcaggcacctCATCGTCAGATCCAGTGTGGCCTGTGCAATGACCGACCCAGCAGCATGGCTGCCCTACGCTCTCATTTACTCACTCATCGCGATGGACACACGGACATCGATCCGCATCAGCAGTCTGCCTTCTTTCGTACCTATTACCAGGATGACGGCGTCAGCAGCCTGCCAGAGATCAGGGTACGCATCGCTGTCGACTTTGAGGCTCAGCTTTATGGAAGATATTTCAATGCGTGTACGGACAGCGGACAGGAACTGGACTTCAACGACTCCGACAAGGAGTGGAGCGATGCGCCAGCTCTGCATAGCTGTGCCGTGTGTGGCGAGAGTCGAATCCGCCTCGATCAGCTGCTCCAGCATCAGCAGAGCCAGCACATTGAGCTGGCGGGCGGACTGCCTCACGTCTGCTCAGATTGTGGATTGGGGTATGTGGCCgagtcgctgctgcagcagcatcgtcGTCGCATCTGCGCCAAGCTGCTTGCCAAGTACCAGTGTCCACATTGCAGTCAGCGGTTCTATTGGCACTCTAACTACGAGCGGCACATTCAGGTGCAACATCCTGCGGAGAGGCAGCAGGGGCAGGAGAAGAGCAAGCTTCAGTGCAGCGAGTGCGATAAGGTGTTCATCTGGCCTAAGGATTTGACGCGCCACAAGCGCATGCATCAGTCGCAGGTCCAGTTCGAATGCGTCCACTGCGATCGCAAGTTCCATCGCAAGGATGGCCTCAAATCGCACATGCGGATGCACGGCGAGCAGCCGACGTCATCGTCTCTCGgtgagcagctgcagcgcatGCCGATGGTCTTGAGCCAGCTGTGTCGCCCCAATGGCTGCAAGCAGATCAAGTGCATGATTTGCCTGTCGCAGCACACAAAGATCTCCGATTTGCGAACGCATTTGACTAGCCATCAGTTGAGGCTGTGTTTGGCCGAGGAGCGAGGCATCGCAAACATTTGTCGAGCTCTCTATCCGGAGCTGAACACGCCATTGAATCAGCAGGCTTTGATCAAGCGCATCCAGCGAGATCTGGGCAatgaactggagctggagagATTCGTTTCGATAACCAACGAGGCGGGCATCGAACTAAGCCTGGACAGCAGCGAAACGGACACGGACTCGGATTGTGCAGTAGAAACCGAACGGAGCTCCATGGAACGCGGTTATAGCTGTGAACTGTGCCAGGTGCAGGTGATGCGCAAATATCAGCTCTATGCCCACCAGCTGGAGAAGCACACGTGGCACCAGACAACGCACGTCTGCAGCCACTGCCAGGCGAGATTTGTAaatgagcagctgctggacCATCACTATCGGACCCTCTGCCGCAATGCCCAGCGGCGTTTCCTGTGTCGCAAGTGTCCGTTGCGCTTTCGCTGGCGCGATAATCTCAAGCTGCACAATGGTGTAGCGCATCAGGAGCGAGGGAATGTGAAGCAGCACTCCAATGTGGACATTCAGTTGCGTATGCTGCCCGTGGTTAGCTACGACTGCGTCGAGTGCAAGCGTagcttcaaaatgcaaaaggatCTCACACGGCACACACTGATGCATGCCCAGGAGTCGAGCATCTATCGGTGTCGCTGGTGCGCTCGACGCTTCTATCGTGAGGCGAACCTGCTGCAGCACATCGAGCGCCATGGCATCAGCGCCGACCAGCTGCCCTATGCGGAGGCCCTGCTCAACGCCAGTCGTCATCCGCACGGCCCGAAGTGCATCAAGTGTCGCGTGTGTGAATTATCCTTTGGAAGCATTGCTGCACTGCGCTCGCATCTGCAATCGTCGGCAGTTGGCACTCATCATCCGATTGAGTCCATGGCCAACTATTCGATCACCAATCAGCTGGGTTACGAGCTGCACCTGGACGACTCCGAAACGGATGAGGAAGCCAAGCCGGCGGGCACCCCGGCGCATTACACGTGCGGCATGTGCCAGCTGCGTTGTGTGCGCAAGTTTGagctgcatcagcatcagcaggccATGCATCGTCTGGAGCGCATAGCCGACGGCTGCGATCTGTGCATCTTCAAGAGCGTCTCGCCCGATCTGATTGCCTATCATCGGCGTGTGCTGTGCGAGAACACGGAGAAGCAGTTCAAGTGCTCTAAATGCAGCTACAAGTTTATGTGGCAATCGAATCTGGTGCAGCACATCCAACTGCAGCATCCCAGCAGCGAGGAGTCGACAACGAAAACATCAATGCCCATGGCCGTGCCCGACATTGCCAACGCCGAGTGCCACATCTTCCAATGTGGTCAATGTCCCAGTAAATACAATCGGAAAGATCGCCTCACCGCCCATGTAAAAAAGTGTCACACAGCTGGCGCAACTGCGTCAACAAAATCGCCAGCGGTTGCCAAGCAGCAGAAAAGTTTCCTATGCGCCTTCTGCGGCAAGGCGGTGAGCTCATCCTCCAATTTAATCATACACATACGTCGGCATACCGGTGAGAAGCCGTTTAAGTGTGATTACTGCGACATGGCATTTCCGCGCTCCTCCGATCTCCAGTGCCATCGACGCACCCACACTGGCGAACGGCCCCACATCTGCACCGTCTGCAAGAAGGGATTCGCTCGCTCCtacaagctgcagcagcacatgCGCATCCACAACGGCGAACGGCCCTACAAGTGCACCTTCTGCGACAAGAGCTTCACCCAGTCCAATGACCTCACCCTCCACATACGGCGCCACACGGGCGAGCGACCTTATCAGTGCAATACGTGCGGCGAGCGATTCATTCAGGGCACAGCGCTCAAGAACCATCGAATGCAGAATGGCCACTATGAGACGGAAGTGGGTCAATCGAAAGTTGACTAA
Protein Sequence: MLPTNVCRTCALQDDNLLALATRSEKYAKKSICDMLHELTQNDPLLEHTDDKLPQHLCGQCLSQLEAAYAFVLQAREAQEQLLLQLRKGLQTQCLDETPIDISIEHIKIETDIDLDADTADAVDAEFEEEQEKHVVLKCQPESDSDSSQDNVKDHDVEVQTLQLRRSARRAKLSTDSENESISEQVKPLPVKRGRGRPRRVAKRETTTNEDGRHVCEVCGKTFSWYRDMQRHARIHFEQAGIVCEHCGKKFLRKDKYMTHLRSHKKHVATDRQILPRSSEWRYAERLYSSGRLMRVECKLCGLSCQRIRELRNHLASHVHIETLWNLSLDNDVIREQFGSQSDLEQIKEQVCTQIAKGREQLENYGAVVNAYGYELCLSDSDEEEDEELSGKYQCLRCNVNFARKYQLVRHTLEEHTDRSETPLERCNVCQIGFVCAKLLEQHQRTQCLNPLKRYSCENCPGKFIWLQNLQQHACSRLQHDLQQELQHRHQEQQQAPHRQIQCGLCNDRPSSMAALRSHLLTHRDGHTDIDPHQQSAFFRTYYQDDGVSSLPEIRVRIAVDFEAQLYGRYFNACTDSGQELDFNDSDKEWSDAPALHSCAVCGESRIRLDQLLQHQQSQHIELAGGLPHVCSDCGLGYVAESLLQQHRRRICAKLLAKYQCPHCSQRFYWHSNYERHIQVQHPAERQQGQEKSKLQCSECDKVFIWPKDLTRHKRMHQSQVQFECVHCDRKFHRKDGLKSHMRMHGEQPTSSSLGEQLQRMPMVLSQLCRPNGCKQIKCMICLSQHTKISDLRTHLTSHQLRLCLAEERGIANICRALYPELNTPLNQQALIKRIQRDLGNELELERFVSITNEAGIELSLDSSETDTDSDCAVETERSSMERGYSCELCQVQVMRKYQLYAHQLEKHTWHQTTHVCSHCQARFVNEQLLDHHYRTLCRNAQRRFLCRKCPLRFRWRDNLKLHNGVAHQERGNVKQHSNVDIQLRMLPVVSYDCVECKRSFKMQKDLTRHTLMHAQESSIYRCRWCARRFYREANLLQHIERHGISADQLPYAEALLNASRHPHGPKCIKCRVCELSFGSIAALRSHLQSSAVGTHHPIESMANYSITNQLGYELHLDDSETDEEAKPAGTPAHYTCGMCQLRCVRKFELHQHQQAMHRLERIADGCDLCIFKSVSPDLIAYHRRVLCENTEKQFKCSKCSYKFMWQSNLVQHIQLQHPSSEESTTKTSMPMAVPDIANAECHIFQCGQCPSKYNRKDRLTAHVKKCHTAGATASTKSPAVAKQQKSFLCAFCGKAVSSSSNLIIHIRRHTGEKPFKCDYCDMAFPRSSDLQCHRRTHTGERPHICTVCKKGFARSYKLQQHMRIHNGERPYKCTFCDKSFTQSNDLTLHIRRHTGERPYQCNTCGERFIQGTALKNHRMQNGHYETEVGQSKVD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00577186;
90% Identity: iTF_00610043;
80% Identity: -