Basic Information

Insect: Drosophila carrolli
Gene Symbol: su(Hw)
Assembly: GCA_018152295.1
Location: JAECXJ010000069.1:8433868-8436984[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.00078 0.059 13.8 1.9 1 20 214 233 214 235 0.94

2 12 2.4e-06 0.00018 21.7 0.4 3 23 286 307 284 307 0.93

3 12 0.084 6.4 7.4 0.0 1 23 313 335 313 335 0.94

4 12 4.8e-07 3.6e-05 23.9 2.4 1 21 342 362 342 363 0.95

5 12 5.4e-06 0.00041 20.6 1.0 2 23 375 396 374 396 0.96

6 12 0.00025 0.019 15.4 6.3 1 23 407 429 407 429 0.99

7 12 7.1e-05 0.0054 17.1 0.9 1 23 435 457 435 457 0.97

8 12 1.6e-05 0.0012 19.1 0.4 1 23 463 485 463 485 0.98

9 12 1.3e-06 0.0001 22.5 2.5 1 23 491 513 491 513 0.98

10 12 0.00014 0.011 16.1 0.6 1 23 517 539 517 539 0.96

11 12 4.9e-05 0.0037 17.6 0.7 1 21 547 567 547 571 0.92

12 12 1.9e-06 0.00014 22.1 0.4 3 23 591 612 589 612 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.00078	0.059	13.8	1.9	1	20	214	233	214	235	0.94
2	12	2.4e-06	0.00018	21.7	0.4	3	23	286	307	284	307	0.93
3	12	0.084	6.4	7.4	0.0	1	23	313	335	313	335	0.94
4	12	4.8e-07	3.6e-05	23.9	2.4	1	21	342	362	342	363	0.95
5	12	5.4e-06	0.00041	20.6	1.0	2	23	375	396	374	396	0.96
6	12	0.00025	0.019	15.4	6.3	1	23	407	429	407	429	0.99
7	12	7.1e-05	0.0054	17.1	0.9	1	23	435	457	435	457	0.97
8	12	1.6e-05	0.0012	19.1	0.4	1	23	463	485	463	485	0.98
9	12	1.3e-06	0.0001	22.5	2.5	1	23	491	513	491	513	0.98
10	12	0.00014	0.011	16.1	0.6	1	23	517	539	517	539	0.96
11	12	4.9e-05	0.0037	17.6	0.7	1	21	547	567	547	571	0.92
12	12	1.9e-06	0.00014	22.1	0.4	3	23	591	612	589	612	0.97

Sequence Information

Coding Sequence: ATGAGCGCCTCCAAGGAGGGCAAGGAAAAGAGGGTCAAGATTATGGGCGTGGAGAATGTTTCGCCACCCAAGGATAAGCGTCCTGCGACAAGGATGAAGCTCTTGAACGACGTTGGAGCAGGTGCAGATCCTGAGACCGCGATCACCACCTCTAAAACCCTTCCAACTAAGCAGGATAAACGCGGAAGCCTCACGGGATCACGCATCAAAATACTCAATGAGGAAATACTGGCCACCCCAAAGGCGGAAAAAAGAGGCTCCACGAAGAGCACAACTCCAGCCGCATCCACCGTCAAGATTCTTAATGATAAAAGGGCTCCCAGCGTCACCGCAACGGCTGTGGAAACTGCCAAAATCAAGACCTCGCCTAGTAAACGGAAAAAAATGGATCACTATGTACTACAGGCTGTTAAAACTGAAAACAGCAAGGTGGTCACGACGGCGATCGAAGAAGATGAGGATACCATTGCTTTTATTTTGGCCGAAGATGAGGAAGTGGTGCCAGGAAGAATTGAGGAAACCAATGGTCAGGAGATCGTCGTGACCGAGGGTGACGAGGACGAAGAAGATGGCGACGAGGATGGGGAGGATTCCAAGGGAATCTCCACCAACGTGGGAAAGATCAAGGAGATCGTGGAGCACGTGTGCGGCAAGTGCTACAAGACCTTTCGACGGGTTCAGAGTCTGAAGAAGCATTTGGAGTTCTGCCGCTACGACAGTGGTTATCATCTGCGCAAAGCGGACATGCTTAAGAACCTGGAAAAGATCGAAAAGGATGCCGTGGTGATGGAAAAGAAGGATATCTGCTTTTGCTGCAGCGAAAGCTACGACACCTTTCATCTGGGCCACATCAACTGTCCCGACTGTCCAAAGTCGTTTAAGACGCAGACCAGCTACGAACGTCACATCTTTATTACCCACTCCGAGTTCAGCGATTTTCCGTGCTCTATCTGCAACGCTAACCTGCGCAGTGAAGCCTTGCTTACACTGCACGAGGAGCAGCACAAGTCGCGTGGCAAACCGTACGCCTGCAAGATCTGCGGCAAGGACTTTACGCGCTCCTACCACCTGAAGCGCCATCAGAAGTACTCCTCGTGCTCGTCGAACGAGACCGATACTATGAGCTGTAAGGTATGCGATCGCGTCTTCTATCGCCTGGATAACCTGCGATCGCATCTCAAGCAGCACCTGGGCACGCAGGTGGTAAAGAAGCCGGAGTATATGTGCCACACGTGCAAGAATTGTTTTTACAGTCTGTCCACGCTCAACATTCATATACGCACCCATACTGGAGAGAAACCCTTCGATTGTGATCTTTGCGACAAGAAGTTCTCAGCTTTGGTAGCACTTAAAAAGCATCGGCGCTATCACACTGGCGAGAAACCCTACAGTTGCACTGTGTGCAACCAAGCCTTTGCCGTCAAGGAGGTGCTCAATCGACATATGAAGCGTCACACTGGAGAGCGTCCACACAAGTGTGAAGAGTGTGGCAAGAGCTTCATCCAGGCCACCCAGCTGCGCACCCATTCCAAAACCCATATTCGCCCCTTTGCCTGCGATCAGTGTGAGGAAAAATTCAAAACAGTGAAACAACTGGAACGCCATGTGAAGGAACACTCGCGCACAAAGCGTCCCGTCTTTTCCTGCACCGAATGCAAACGTAGCTTCCGCACAACGGCCCTCCTCAAGGAGCACATGGACGAGGGAAAACACAGCCCGAAACAACAACGAGTCAAGCGCTCGGCCAACAAAATTATGGAGCGAACAGATTGCGCCATTTGCGATAAGAACTTCGACAGCAGCGAAACCCTTCGCAGGCACATTCGTACCGTGCACGAGTGCGATCCGGATGACATTTTCGGCGTTGAACCTCAGACTCCGAAGCGAGCAAAGAAGGTGAAACTGTCTGGAATAGAAGTGGAGGAGGTTGTACCGGTGGCGCTGAATACTTCGGCGGGATCCTTGATTTCCAGTCAAACAGATGGAAACGGCGTGGTGGTCCGAGAATTCTTGGTGGACGAGGGCGATGGCACTGCCCAGACCATTACGCTGGAGAACGAAACCTACACAATTCTGCCTTTGGACGGGGCCATCGAGGGAGAGCAACTGACGGATGAAGCTGCAGTGAAGCCTGAGGGCAAAAAAGATGAGGCGAAGGTCTCGCCGGTGGTCAAAAAGGAGCAGCGCAAATCACTGGCCGCCAGTTTGGCGGCTGCCATCGCTGATAATCTGGAGGAGGCCTCGAGCGAGGAAGATGTCGTAGGTGAAATCCTAACCGAGGAAGACCTACGACTCAAGGAGAACGTGGGAAAGCTAATTGACATGCTGGTGGATCCACCCATCTTGAAGAAATACGGCTGGCCAAATGCCGCCGAGGAAATGGTGCTCTGCAAAGTGATCGAGAACTGTGGTCACGATTTGACCAAAGGTACTGAAAATTACGCTGAACTGGACTATGGCAGCCGGATGCGAGAGTATTGCAAACTGCTCTTCACCGTGGTCATTCATAACGATTCCATCAAGTCGCTCCTTAACAATTTCCCCATCGACGACGTCATCGAATATGTGCTGGGAGATGAGGACTCGGAGGATGTAGGGTTTGGCAAGGATAAAAGGGACGATAAGGAGTCTAACACAGAGGATGATGAAGCAGAGACAATAACAGGCGATGCTGAAAAAGAAACGGTCCCAGCGAAATCAGAAAATAAGACAGCCACTGCGAAAACTGAAAAGGAGTTGATCACAGAAGATAAGAAAAAAACAATCCCAGCAGAAAATGAAGAAGAAAAGGTTTGA
Protein Sequence: MSASKEGKEKRVKIMGVENVSPPKDKRPATRMKLLNDVGAGADPETAITTSKTLPTKQDKRGSLTGSRIKILNEEILATPKAEKRGSTKSTTPAASTVKILNDKRAPSVTATAVETAKIKTSPSKRKKMDHYVLQAVKTENSKVVTTAIEEDEDTIAFILAEDEEVVPGRIEETNGQEIVVTEGDEDEEDGDEDGEDSKGISTNVGKIKEIVEHVCGKCYKTFRRVQSLKKHLEFCRYDSGYHLRKADMLKNLEKIEKDAVVMEKKDICFCCSESYDTFHLGHINCPDCPKSFKTQTSYERHIFITHSEFSDFPCSICNANLRSEALLTLHEEQHKSRGKPYACKICGKDFTRSYHLKRHQKYSSCSSNETDTMSCKVCDRVFYRLDNLRSHLKQHLGTQVVKKPEYMCHTCKNCFYSLSTLNIHIRTHTGEKPFDCDLCDKKFSALVALKKHRRYHTGEKPYSCTVCNQAFAVKEVLNRHMKRHTGERPHKCEECGKSFIQATQLRTHSKTHIRPFACDQCEEKFKTVKQLERHVKEHSRTKRPVFSCTECKRSFRTTALLKEHMDEGKHSPKQQRVKRSANKIMERTDCAICDKNFDSSETLRRHIRTVHECDPDDIFGVEPQTPKRAKKVKLSGIEVEEVVPVALNTSAGSLISSQTDGNGVVVREFLVDEGDGTAQTITLENETYTILPLDGAIEGEQLTDEAAVKPEGKKDEAKVSPVVKKEQRKSLAASLAAAIADNLEEASSEEDVVGEILTEEDLRLKENVGKLIDMLVDPPILKKYGWPNAAEEMVLCKVIENCGHDLTKGTENYAELDYGSRMREYCKLLFTVVIHNDSIKSLLNNFPIDDVIEYVLGDEDSEDVGFGKDKRDDKESNTEDDEAETITGDAEKETVPAKSENKTATAKTEKELITEDKKKTIPAENEEEKV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00486704;
90% Identity: iTF_00512138;
80% Identity: -