Basic Information

Insect: Drosophila buzzatii
Gene Symbol: -
Assembly: GCA_035045845.1
Location: JAWNOS010000495.1:300291-329259[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.03 2.4 9.0 0.7 1 23 1296 1319 1296 1319 0.96

2 8 5.2 4.1e+02 2.0 1.0 1 23 1324 1347 1324 1347 0.96

3 8 0.00037 0.029 15.0 0.5 1 23 1570 1593 1570 1593 0.96

4 8 0.005 0.39 11.5 0.5 2 23 1602 1623 1601 1623 0.97

5 8 0.049 3.9 8.4 0.3 1 23 1630 1653 1630 1653 0.96

6 8 1.9e-05 0.0015 19.1 1.4 1 23 1659 1681 1659 1681 0.97

7 8 1.4e-05 0.0011 19.5 0.5 1 23 1686 1708 1686 1708 0.97

8 8 0.00076 0.059 14.1 2.5 1 23 1714 1736 1714 1736 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.03	2.4	9.0	0.7	1	23	1296	1319	1296	1319	0.96
2	8	5.2	4.1e+02	2.0	1.0	1	23	1324	1347	1324	1347	0.96
3	8	0.00037	0.029	15.0	0.5	1	23	1570	1593	1570	1593	0.96
4	8	0.005	0.39	11.5	0.5	2	23	1602	1623	1601	1623	0.97
5	8	0.049	3.9	8.4	0.3	1	23	1630	1653	1630	1653	0.96
6	8	1.9e-05	0.0015	19.1	1.4	1	23	1659	1681	1659	1681	0.97
7	8	1.4e-05	0.0011	19.5	0.5	1	23	1686	1708	1686	1708	0.97
8	8	0.00076	0.059	14.1	2.5	1	23	1714	1736	1714	1736	0.99

Sequence Information

Coding Sequence: atgggCACAGCTGACCCAATGAATGCAGCAAAGGATGTACACGACGTGGACgatggcgttggcgttgcctTTGGAGATAATGGACTTAATAAATTTGACGCCAGCATTGCTGACGACGTCGGCATCGGTGAGTTGCTTGAAATGCCGCGCGtgtgtcgctgttgctgcaaaggCGACATGGAATTGCTTAGCCTGTTCGAGGCCAGCGACGAGAcagccaaacaacaacagcagacaacaacaaaaacacaacgTCGACgcaaaacaacaagaacaacaacagcgacaacaacgacagaaACAACACAACTGCAACATCAACAGttactacagcagcagcagcagcagcagcagcgcaaaaGTGAAAATCCTGTGGAATATGCGCTCAGCGGTGCGCACAGCAGCATGGAAACTGTGCGCGAGGAGATGTTCATTTGGATGCTCAATaTCGCATGTAACGATGGCCTTCCGCAGGAGATTTGCCGCCAGTGCAAGGCGCAGTTTATAATGGTGGCCAAGTTTCGGAGACGCTGCTTGCGTGTGCAGTTGCGTCTGGAGCAGTATGCCAAGAAGATATCCGAGCGCAAACAACGTTTGGCTGCCAAACTTGAGAGTAGTGCACAGTCAAATGATGTGCCTTCAGAAGATTATCTTCATCTGCCCGAATTGCAAGCGGATCGCAAGCGACGTCTGGGGCTCAGTATGGCAACAACGCAGCCGCAGTCCAAAGTAAGCAGGACTGAAGCCCTGACCGAGATGCCGACGGCGTCGAGTGCGCAACACCAACAGCTCCGTGCGCGTAAAGTGCGAACTGCTTCTCTGCCAGCCTATATAATAAAGACTGAACCAACGCCGGCGATTGCGACACGAAGTGCGTCCCAGCACGGCGAAGTAAGGTTGAGGGGCCGAACGCCACACAGGTCGCCGTCCAAACGAATACAGATTCCCTGGAAAACAAAAGCGGCGCGCAAACAGCTTTCCGAAACGTTGTCGAGCTGTTCGCCCAAGTCTAACTGCGGCACAGACACCATGATGTCGGATGAGTTGCCAAAGGCCCGATTGTTAACGATTCCCTCAGCGCAAAGTTCCGAAACAGAAACGGAAACAAGCGCTGGCAAAACGTCAACAGAGGAGCTCAGTGATATGTCTGTGAATCCATGTCATGGCTTTGACGTAGATGGCCACAGCTGCTCTTCCACAACTTCTTCCTGCTCATCCGCTTCCTCAACACCAGCTACGAGCGCTGGCCAAAAGGCGACCATGCCTAAATCGAATGCCAAGCTGAGATTTCCACCAAAGCGAAGGTTGCCTAAAAAGCCTATGATGGTGCGTAGTGGACGCAAAACGCGAATCAACTCTATGCCGCTCAAACGATTGAGGAGCAACACAGGAAAGAAGCAGACGGACACAACTGTTGAGAGCCAATTGTCCGATGAATTGATGAGAGAACAGTGTAGCAGTGAAATAATTGAGGAGTCACCACAGATGACAATCGACAGGGAGACATTAGAAAAGTTGGAAAGCAGATCTTCGGATGAGGTGCCGCACAGCAGTCTCCTcaatacatacacagataTGAGCTCGGAGaagcaactgtcaatcacaagaGACGAACCGAAGGTAAACTCGAGCGAAACAGCGACCACAGAAACTGAGCGCGACATGGTAAATACCTCTGTGGAGATAAGAGATTTCAGGCAACAGCAGGAAGCCGCTGCAACTGAACAGGCACAGTCGCCAGCTCCGTCGGAGCCAGTAAAATCTTCTCAAGAGAATGAAATCAAAGAAAGTCAGGCCACAATGCCAATTGAACAAATAGAAAGCATATCAAAGGAAGTGGGCGTGCCAAGCGAAGCTGAGCTTGTGGGAGAAAGGAAAGCAACGAATGGAGTTGCAGAGACAGCTGATTCGACTGTACAATTCGAAGAGCTGACGTCGTCCACCACTGAGCAAGGCAGAGAATCTCTGACACCCGAAGTGCCAGCAGCGGAGTTTGAAGTAGAGCTGCAACTAACGAATAAGGAGCATCAGCTGGAGGAGGACTCACAGTCAGACGGGGAGGCCAAGGAGTCAGAGCTGAAAGTAAGCATACCCTTGGACGTGCTTGACGATGATCTGCAGCGTAAGCTATGCAACAGCTCTGATGCACAGGCTTATGTAGTGCAGCAGGAGACCGAGCCCAAAGAGCCTGCGGAATCGGACGATGTGAACAACAACGAGAATGGCGAGAATTTTTGCCAGAGTGCTACAGCAGATAGCTTCAATGCTGCTGTGGCACTCACAACCAAACAAATTGAAGCAGAACCCAATGGGGGCGTGACTGTGACGGCAACACTGGATGATGACATGGAATCGTTGGAGCGATTGGCCaatttgcagcagcatcagccaGTGAATGAAGTGCAGCTGCCCCGTGCCTGCAATGCCAGTTCCATGGACTTTTTGGCCGAATTCGAGAAGCACTGCGAGAAGACACTGAAGCTACAGTCGCAGTCAAAGTCGCAgatgcagtcgcagtcgcagtcaaaGGCGGCGCCACTCAATGTGGAACTCGAACTGGTGGAggccaagcagcagctggaagTGGAGATGAATGATGTGGAAAGCACGCTGCATGGCATACTCAACGAAATGCAAGATCAGCACCTCTACACGCCCGTTTGCACACCTATCGATGAGTTGCTGACGCCTGCGGATTATGTGGTGCTCCATGAAAGGGATGCGCCAGTGCCAACGCCAGCAGCAACGCAGCTCTATGAGCCGCCGGGTGAGACAATTCAgtcacaacagcagcagcagcagcagcagcagcagcagcagcaacagcaacagcagcagcaacagcagcagcaacagcaacagcagccgcagccgcaggtGAAAGAGGGTAATCCGTTCGATAGCAGTAATTTTAGCAATGAGCTGATTGGCTTCCAGAACGATATGCCATGCTTCGAGAATATTGAGGCAACGTCTGAGCCGATGGCATCGCAGCAGAgcctgcagctggagctgacGCAGTTGCTTAATGAGCTGCAGCCAACCCAGCAGCCATTACAGccggtgcagcagcagcagcagttgcagttacaGCCAGAGGCAGTCAACTATGAGGCACTGTATCCAGTAGCAATGCCTGCTGCCTCAGCGAACAACAGCAAGTTGCAGGTAATTCAGATGCAGCCACAGGAGACACTGTGGCAGGCGCAGGGAACTGCCGCTCAACCGACGACAGCCACGCAGTTGCAGTGGTCGACGGTGGGCGGTTTGGAGGCCATCAAGACAGCACCTGTTGCCGGCGTAGATACTCTAGATGGCAGTGGCACAACCACCTACTATATCAGTGCCGGTGATCTCTACCAGACGCAACTGCAGCCACAAACGGCGCAGCTAACGGGCGATAGCTACGCGCTGCTGGACAGCAATGAGAACTATGTGCTagagcaacaggagcaacaacaacagctgcagtcacagcagcatcaacagcagcagcagcagcagcaacaacccaTTATGATACTCATACAGCAGCCGGAGCTGCAACAGCCGGTTGCATCCGCCAGCAAtccgcagcagccgccgctaCATATAACTTATGGCGCCAATCTGAACAATGGGCTGCACGTGGCCTATCCgccgcaacaacaattgcagcagcattcaccacagcagcagcatcaagaGACGCAGCCACAATTACAGCCCCAAAGTCCGCAACAACAAGTACAAAATACAGTATTAAGCTTACCTGCAGCCGTGTCGCCCTCCACACGAAGCCGTACGCCCATGTTGAAGTGCCGCTTCTGCCAGAATGGACCACGTTTCTTTAGCAGCGTGGACTACAGTCGTCACATCATTGAGCTGCATCCGGCTGTGGCGCCATTCAACTGTCCTCATTGTCCGCTGGCCTTTGCCGGACGCAACAAACGAAACCAGCACATCCTTAGCAATCACATGATGCAGCAGTTCCACTGTGGCCAATGCTCACAGCTGTTGCCTTCGCAGCGTGCTCTGGACTTACATTTGCAGCGCTTCCATATGCCGTTGCCTACCgagccaccagcagcagctgctcctggCGTGCGCCTCGAAGAGGTTCAATTGCAaatagccaacagcaacaccaacaacaacaacagcagcaaccataACAACACCGAACAGCCGAAGCAACTCAACCACCAccagccagagcagcagcaacataggCAACCACTGacgcagcagcaccaacagcataTGCCTTCTTTGGAATTGCAAGCAAGTTCTCAACAGCCACGCAGAACGCGCATACTCTGCTGCCCAGACTGCGAGGACTGCTCTACGGCCAGCGGACATAGTCATGGCAGAGGACAGTCGTCGTTTGAGGAGTTGTCGAACTTGCAGCCACTGCCAAATGTTTTAACGCCGCCTTCGACAATTGCATCATTGCCATCTCCTCAGCCGACGCCGCACATAACAATGCCATCGCCGGAGCAATCGGAGCCGGACTCGACGACGGCCACATTGAGGCAATTCCGCAAGCGCAACACGCCCACCAACTTTACGACAGCAGGAACTTGTTCCATGGCAACATCAGCGACAATAggtacagcagcaacaacaatgctatCGACAGCTCcatcgccgtcgccgtcaTCATCTCCGTCCTCATCGACAATGGAGTCGAGCGCCACACTGCAGCTGGGCAAATTGCGCAGCAGCTATGAGTGCGTCGTTTGCGAGAAGCACTTCACGAATGTCATTGCGCTGCGCAAGCACCAGCAGCTAGCCCATGATTCACAGACAACGATGCCTTGGGTGTGCGGGATTTGCAAGCGTGGCTATCGGAAACGAACCGACATGGACAACCACATGAAGTCGCACGAGCCGAAGGGACGGCCGTACGAGTGCAACGAGTGTTGGGTACGTTTCCCGGAGTTCAAGCAGCTGGCCATGCACAAGTTCACCGTCCATGAGCTGATCAAGCCGCATACCTGCGATGAGTGTGGTAAACAATTTGGTACGGAGAGCGCCTTGAAGACGCACATTAAGTTTCACGGTGAGCGCGGCTTCGATTGTGAAGAATGCGGCGAGGTATTCGTTTATATGAAAGATTTGCGTAAACACCGTCGCAGCCACAACAGcgaattattttacaaatgcGGCGACTGTCCGCGCACGTTTCTACATTTTACGAATTATCGGGCTCATATAAATACACACCTGCCACTGGGAGTATTCCTCAACGATAAATTGCCGAGCAGCGTAAGCAGCAAACTGGAGAACCCTTCAATGCCAGCAGCTATCGAGGAATCCTCATTGCCATTAACGCCGCTTAGCAattgcaatggcaacagcggcagcatcgACGATTGCCCTGGCTCCGTGGAACTGGTGGAAAGCAGCATGACGCCATCGCTGGAGATGATTGTGGATGCGCCATAA
Protein Sequence: MGTADPMNAAKDVHDVDDGVGVAFGDNGLNKFDASIADDVGIGELLEMPRVCRCCCKGDMELLSLFEASDETAKQQQQTTTKTQRRRKTTRTTTATTTTETTQLQHQQLLQQQQQQQQRKSENPVEYALSGAHSSMETVREEMFIWMLNIACNDGLPQEICRQCKAQFIMVAKFRRRCLRVQLRLEQYAKKISERKQRLAAKLESSAQSNDVPSEDYLHLPELQADRKRRLGLSMATTQPQSKVSRTEALTEMPTASSAQHQQLRARKVRTASLPAYIIKTEPTPAIATRSASQHGEVRLRGRTPHRSPSKRIQIPWKTKAARKQLSETLSSCSPKSNCGTDTMMSDELPKARLLTIPSAQSSETETETSAGKTSTEELSDMSVNPCHGFDVDGHSCSSTTSSCSSASSTPATSAGQKATMPKSNAKLRFPPKRRLPKKPMMVRSGRKTRINSMPLKRLRSNTGKKQTDTTVESQLSDELMREQCSSEIIEESPQMTIDRETLEKLESRSSDEVPHSSLLNTYTDMSSEKQLSITRDEPKVNSSETATTETERDMVNTSVEIRDFRQQQEAAATEQAQSPAPSEPVKSSQENEIKESQATMPIEQIESISKEVGVPSEAELVGERKATNGVAETADSTVQFEELTSSTTEQGRESLTPEVPAAEFEVELQLTNKEHQLEEDSQSDGEAKESELKVSIPLDVLDDDLQRKLCNSSDAQAYVVQQETEPKEPAESDDVNNNENGENFCQSATADSFNAAVALTTKQIEAEPNGGVTVTATLDDDMESLERLANLQQHQPVNEVQLPRACNASSMDFLAEFEKHCEKTLKLQSQSKSQMQSQSQSKAAPLNVELELVEAKQQLEVEMNDVESTLHGILNEMQDQHLYTPVCTPIDELLTPADYVVLHERDAPVPTPAATQLYEPPGETIQSQQQQQQQQQQQQQQQQQQQQQQQQQQQPQPQVKEGNPFDSSNFSNELIGFQNDMPCFENIEATSEPMASQQSLQLELTQLLNELQPTQQPLQPVQQQQQLQLQPEAVNYEALYPVAMPAASANNSKLQVIQMQPQETLWQAQGTAAQPTTATQLQWSTVGGLEAIKTAPVAGVDTLDGSGTTTYYISAGDLYQTQLQPQTAQLTGDSYALLDSNENYVLEQQEQQQQLQSQQHQQQQQQQQQPIMILIQQPELQQPVASASNPQQPPLHITYGANLNNGLHVAYPPQQQLQQHSPQQQHQETQPQLQPQSPQQQVQNTVLSLPAAVSPSTRSRTPMLKCRFCQNGPRFFSSVDYSRHIIELHPAVAPFNCPHCPLAFAGRNKRNQHILSNHMMQQFHCGQCSQLLPSQRALDLHLQRFHMPLPTEPPAAAAPGVRLEEVQLQIANSNTNNNNSSNHNNTEQPKQLNHHQPEQQQHRQPLTQQHQQHMPSLELQASSQQPRRTRILCCPDCEDCSTASGHSHGRGQSSFEELSNLQPLPNVLTPPSTIASLPSPQPTPHITMPSPEQSEPDSTTATLRQFRKRNTPTNFTTAGTCSMATSATIGTAATTMLSTAPSPSPSSSPSSSTMESSATLQLGKLRSSYECVVCEKHFTNVIALRKHQQLAHDSQTTMPWVCGICKRGYRKRTDMDNHMKSHEPKGRPYECNECWVRFPEFKQLAMHKFTVHELIKPHTCDECGKQFGTESALKTHIKFHGERGFDCEECGEVFVYMKDLRKHRRSHNSELFYKCGDCPRTFLHFTNYRAHINTHLPLGVFLNDKLPSSVSSKLENPSMPAAIEESSLPLTPLSNCNGNSGSIDDCPGSVELVESSMTPSLEMIVDAP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00599903;
90% Identity: -
80% Identity: -