Dbuz012065.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila buzzatii
Gene Symbol
Hivep2
Assembly
GCA_035045845.1
Location
JAWNOS010000491.1:1217133-1225385[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 8 0.00017 0.013 16.1 0.5 1 23 213 235 213 235 0.98
2 8 0.0016 0.12 13.1 3.6 1 21 241 261 241 265 0.89
3 8 0.013 0.98 10.2 0.1 1 19 899 917 899 920 0.93
4 8 2.8e-06 0.00022 21.7 2.0 1 23 1641 1663 1641 1663 0.99
5 8 3e-05 0.0024 18.5 5.3 1 23 1669 1693 1669 1693 0.92
6 8 0.00058 0.045 14.4 3.4 2 23 2185 2206 2185 2206 0.97
7 8 0.0008 0.063 14.0 1.2 1 23 2212 2236 2212 2236 0.91
8 8 0.0026 0.2 12.4 2.7 1 23 2257 2281 2257 2281 0.92

Sequence Information

Coding Sequence
ATGACGCtacagcacagcagcaacaccagcagcagcagcagcaccagcaacaacaataacagcagcaacagtgacactgtcagcaacagcaacacaaatacaaacaacaatgatgttgctgctggtgatgcAACCATTGCTGACTGGAAGAGCAGCTCCAACAACAATTCGCGCTATTTGCACAAGAAGTTCAAGCGTTTGGCCAGCACCACCGAAACGGAAGCAGCTGGCGAGCCAACGTTGCGCAGCACATCGCTGTCGTCGAACAGCTCATTGTCGCCGCCAACGCAATTGCCGCTGGTCAATGGACACgagcacagcaacagcaacaatcatGAGGGGGAGAGCTATAGcaaaaatgttgctgttgctggcgtgCCGCGCACGCGTACGCCtttgagcaacagcagcagcaacaacataagcagcagcagcagcaactatgcCAGCAATGCAACATTGTCGCCAGCAACATTTgcacagcatcagcagcaaacgcagccaacgacaacagcagcaacagcagcagcagcagcagcaacagtcacgccagcagcaacaactgcaagcTCTGctgcgccagcagcaacatctgccacagcagcaacagtcacGCCAGCAACTGGCCTCAGTCGCTACACCTGCCCCTATTGCAATCTGATTTGTGCCAAGCCCTCGGTCCTGCAGAAACACATTCGTGCCCACACCAACGAGCGCCCATATCCCTGCGAGACATGCGGCATTGCCTTCAAGACGAAAAGCAACTTCTACAAGCATTGCCGCTCCCGCTCCCATGCGGCGCGCATGCGCGGACTGGATGTGCCGGCCCACGAGGCGGATGGATTATCCGATCAGGATGGCGACGGAGATCTCAGCAATAGCAGCTCGGAGCTGCTGAGTGTGGAAGTTCAAAGTCGCGCTGATTCGCCATTTGATGAGCAGTCGATGGCCTCGCTGCCCTACATACCTGCATACCTGGAACAGCCGCGGGTCATACAGCCTCTGCCGCTGGGCTCACCTGCTGCTGGCACATTGCCGCCAGTAACAGTGGAGAACTTGCACTCGGCGACAGCGCTGCATCGGCAGTCTATAGACTATAAGCCATACAAGCCAAAATTTCATAATGCAGCGCTCTATGCGCCAGGCAGCAGCacggagcagcaacagcaacagcagcagcagcagcaacaacagcagcagcaacagcagcagcaacaacagcagcaacagcagcagcaacagaaactgCTGCAACCATTGCTCGTGCATCCCACGCTCTCGCCTAGCacgcagctgaagctgaacaaTCACATTAACTcgcatcagctgcagctgcagttgcaacagcagcagcagcatcagcagcaacaacaacaacagcagcagcatctgcagcagcagcaacaattgctgttggcagcagctgcaggcaaTGCTGTTGCTCTGCCGCCACCGCCATTGCCGACGGGCGTCTTCTACCTGGGACAGCCGCCATATTACAAcccgacagcagcagcagcaatgcatcAGCATGCGTtcgcgctgcagcagctgcaatatcagcaacattatcagctgcaacagcagcagcaacaacatctacaacagcagcaacactcgCCATTGCTCAAGGTGCCAAcacagccgccgccgccgccgccgcagcagcagcagcaacagttgctgccacaacaactgcagcagcaacagcaacagttgctgccacaacaactgcagcagcaacagcagcaacagCAGCTATCCCGCTCTAATAGTCAAcaagcaacagttgcagcagcagcagcaacacctgccacgcccacacctgTAGGCAATCTCAGCAGCTTTGCCAGCGGCATGCAAGTGAATGTGGAAAAGGTGCAGGAGCACATTTCGAAACTGATCTCACAGAACGAAGCCATCGTGGAGAATAAGGAAATATTGCTGCAAAAGAAATATCCCAAGCAATTGAATCGTTCGCGCAGCTtcaacaatgccaacaacaacaatggcagcaacagcaacaacagcaacaacagcaacagcaatagcagcagcagcaaccagcaGCTGGGCGATGCTAAAGTAAATCTAGCACAGAGCATAgtacaaaagcagcagcaacaacagcagcaacagcagcagcaacagcagcagcagcaggtgcaattgcagcaacaacagcaattgcaacatATGCAACAATATAGAGTCGTTGAGCCGGTGAATGGCATGCtcaagcgcagcagcaacagcaataatgcGTATGCAAATGTAAAAGCCACGCCgcctgcagctgctcctgctcctccggctgctgctgctgctgccatgaATGCAAAGTTGCCATCGCCAGCAACaatgctgcaattgctgcattATCGTCAGGATCCAGCAATGCCTTTAAACAagctcgagcagcagcagcagcaacagcaacaagtcaCGCCCGCGCCGCAGCCCTTAAATCTCTCTGCCAAACCAAAGCCAGCAAagccagcgacaacagcagcagcaacaacagttgcaacagcagcggcagcagcagcgatacCAGCAACAtctgccacaacaacaattgctgccaagccagcaacagttgctacTGCAGCCGCCAATAATTCGATTATCAAGAATCTATTGTTGAACGCACGCGGCTTGGCCGTGCCCATTGGCGAGGGCGACGACGCCGTCTACTCGTGCCCGATCTGCGCCAACGAGTTCCGCAGCGCCGACGAACTGAAGCAGCATAACAGCACCTACTGCCAGGATGCCAGCAGCAGTGCGCCCATCAGTCCCGCCTCCTCGCCCAGCAGCAAGTACTTTCGCTCCAATTCCATCTCGCTCAGCCTGCCCGAGCTCAAGTCTCACATGGCCAACTCGAAGAATCCGCTCTCCCTGGCCAAGCTGGCCTGGTCGCAGCTTAAGACGAAGCCAAGCAGCCTGGTGCTGAGTCGGCTGAGTGCGGCGCAGTCACCGGCACGCACAAgcacgacagcaacaacagttgctggcagcagcggcaacaactatctagctgcaactgttgccaacagcagcagtgccAGCAATAGCAATCCCACAGCAACcattgccagcagcaacaatgtaTACAGCAACACTCACAATCTGCCAGCAACATTTGCCGTTAGCATCGATGCCAACAATGTTGCTCTGCGCTTCGTGGACGCTCCTCTGCCCTCGCCTGGCCCGCTGCTAGGCAAGACGCCGCTCGTCGACTATGCCGCTCCGCGCAAGGCTGCCGACGCTCAGGTCGTGATCACCAAAATGCACGAGGATCGCCTGGAGAACATCATCAGCGAGAGCTCGGCGAAGCGAGTCAAGCTGAGCAACGAGAGCAATGCCTTTGCCCTGCCCgcgtcaacagcagcaggaggcgtgcaacagttgctgttcAACAACAGCCAGGAGCTGCCTGGCTTCAATACGGGCAAGGAGGAGCGTTTGAGACGCTTCACCTCGTCGGGTGGCTCAATGATTCCCATCTCCGAGTGCCCCGAGCTGGACAAGAGCCCGAAGATGATCCGTACGCCCTTACTCTCTGGCGGCAGCTTTCAGGAAATGTCGCCACGTCTGAGTGAGCCCAAGCCGAAACCCGCCTTTCTCAtcaatgccagcaacaacagcaacggcaacaacaacagcaacaactcgcAGCATTTCCAGTTTCCGCCCATCAATTCGATAACCGCCTTCAATCCCCTCACGCTGCCCGCCATGAGCGAGTCGAGCAGCAAAGCTATTCCCTATGTGCCGGGCATTCCAGGCCCGAGCAGCTTGACAATGCTGCCAGCTCCTCCGCCGccgcaacagttgctgctgccgcgtCCGCCCGCCATTGATGCGCCGCCCTTCAAGAAGTCTTTATCCCCATTCGGAGGCGTCCAGAATCTGCCCAGCGAGTTCAGCCGGCAGCCGCCGACGCCTGCCCAGCGCAATGCATTGCAGtggcagagcaacagcagcaacaagctggcagcaactgttgctgctgctgcaggcgaTGGACTGAGCATGCAAAAGTTTAATTTCCTGCGCATGGCAGACAATCtaaaggagcagcagcagcaggaagtgCGACATTTCATCTTTGATCCGCTGCATGTGGAAACACCAGAAAATGatggaacaacagcagcagcaacatcagcagctgcagcagcagcagcaacaacagcagctgttaCGGCAGCAACATCAAGTGTTGcggcaacaacatcagctggcacagcaacaactgttgccAATAAGACGAAATTCCTGCGTCCCACGAGTCTGCCGCTGAAGCCGGGCACATTCACGCCCAAGCGTCATCATGGCATCACACCGACTGCCAATACACTGCCCTTGATCTCGCCCGAGACGCCGCGGCCGTCCAAGTCCTGCGTGCAGCTCTACCTCAATGGCCACGCCTACACGTACCTGGGCCTCAAGTGCAGCACGAAGATGTTCTACTGCACAGTGAACTGCCCGCAGCCCTCGTACGTGGCCGGCATGCACAAGCTGTCGATGTACAGCGTGTGGCAGGTCTGCGAGGAGAACCAGCCGCATCCGCTCGGCCTCAAGCCAAAGCAGGTGATGTCACTCTACGACTCCAGGCAGAAGATGTTCGGCACTGGCTACACTGTCGTCCAGGCGGGCGCCAATGCGCACAGCTACGCGCTCGTCGGCTCCCAGCAGACGATCAGCAGCTGCTCCACCACGAGCAGCACCCAGAGCAAGTTCTACCAGCACCAGACGACGAAGCAGGCGCCAGCCATTGGCGCGCTCAGCGAGGCCAATGTGGCGGCCAAGGCGAACGAGGAGGCTGCCAAGAAGCTGGAGTCGGGCCAGCTGCTCGTGGGCGGCTATGAGTCCAACGAGAACTATACCTACATACGCGGACGTGGGCGTGGTCGCTACGTCTGCTCCGAGTGCGGCATACGCTGCAAGAAGCCCTCGATGCTCAAGAAGCATATTCGCACGCACACGGACGTGCGTCCATTTACCTGCAGCCACTGCAGCTTCAGCTTCAAGACAAAGGGCAATCTGACCAAGCACATGCAATCGAAGACGCATTTCAAAAAGTGCATTGAACTAGGCATCAATCCAGGTCCCATGCCAGCGGATGGTGAATTCTTGGACGTCGACGTGGAATTCGATCAGCAATCTTCAACCTCGGCTGGCGGACGCACTTCCTCCATGGCTGGCGACTCTGCAGATTCGGATGATTATAGCGATAACGAATCGGAGAGCAGTGACACTGATGAATCCAAGTCGCGCTTGAAGGAGCATGAGGCAGCGCGTGGCCTGCTGTCGCTCTCGATGACGCCGCCCATACCGCAGAGTGTGTCGCCCTATCCCGCACAGCTGGAGGCCAGCATGTCGGCAGCGAGTCCAGCGAATAGCATTGGCTCAGCGGGCGGCGCTTCCACGCAGCCCAAGCGTCAGGTGTGCTCCTTCACGTCGCCCAAGCCGCCGTTCGACTATCAGAAACAGGAGCAATACTATTCGAATCCCGAGGAGTCGAAGCCCAAGCGGCAAGTGCCCGCGGATGAGAGCAGTGCGCCAATGGATCTGACAAAGCCAAGACAaattgccacagcagcagcagcagcagcagcagcaacggcaacggcagcaacatcggcagcagcagcaacagttgctgtcgtAGACTTGCCCAAGTCGCAAGCACAGCAAATGCGCGACGTCATctttggcgctggcaacaacGAGTGCGGCTTCATGAAGACGCTGATCTCGGTGTCGGACAAGGTGCGCATCTCGGCCGAGATGGAGGAGCAGGCGAAgcgcgagagcgagagcgaggaTGTGCTGCTGCACACGTACATCAAGGAGCAGGCGCTGCACAATGCCAAGCGTAAGCAGAGCAtgtacaacagcagcagcagcagctacctgatgaccaccaccaccaccagcagcagcagcagcagcagcaacacgactaccagcagcagcagcagcagcaacatgccCCTTGTGAGCAGCAGTCAGCCAAAGGCGGGCCTCATATATCATGAGGTGCCCAGCATAGAGGTGCATGAACCAGAGCCCACCGAGATTAAAGAGCCAAAGAAGGAACAAGAGCcaatggagcagcagcagcagcttaaagCAATTGCTGTGAGCAGCCAGGAGAAGCAGCCGCTCGAGGCAACATTGGCTGTGCCAGCTCCCGCTCCTGCCACGCACAATGCCAATTTACCAGCTGCTGTGCAGCATCCAGATGCCATCGACTTCAAGGGCGTgctgagcaacagcagcaacacgaaGCCCATTGtgacgacagcaacagctgctgcggctgccactgcaacagcaacagcaacggccaTAGTCAAAGTGCTGGCTCCCGAGGAGAGCTACAAGTCGAGCAGCGAgtcggcagcagcaacgccaacaactgcagctgtaactgcaacaacaacagccagcagcagcagcagcagcggcggcagcggcagcggctaTGGAGGACGTGTGGTGCcagcgccgccgccgcccatTGCCAGCGATGCGCGGCCCACGTGCCTGCTGTGCAGCAAGACGTTCCAGCGGCAGCATCAGCTGACGCTGCACATGAACATCCACTACATGGAGCGCAAGTTCAAGTGCGAGCCATGCAGCATCTCGTTCCGCACGCAGGGCCATCTGCAGAAGCACGAGCGCTCCGAGGCGCACCGCAACAAGGTGATGATGACGTCGACCTTTGGAGTGCCAACCACTTCGAATCCGCGCCCGTTCGAGTGCACCGACTGCAAGATAGCCTTTCGCATACACGGCCACCTGGCCAAGCACCTGCGCTCGAAGACACACGTCCAGAAGCTGGAGTGCCTGCAGAAGCTGCCCTTCGGCACGTACGCGGAGATCGAGCGGGCGGGCATCAGCCTGACGGAGATCGACACGAGCGACTGCGAGAACTCGCTGATCTCGCTCAAGTTGCTGGCCCAGAAGCTGCTCGAGAAGGACCCCAACAAGCTGAGCGGCTACACGACGCCCTCGGGCATGCTGCAGCTGGTGGGCGCCGGCGAGCTGCCCGCTGCCAACCAGGACAGCGCCTCGGAGGACGGCTTCAGTGCGGCGAACAGCGCCGCGGCCTCGGCCATCGCCTCGCTGGACAACGACAGCGCCGGCAATACGCCACAGCGCGCCAGCTCCATGTCCGAGGACGAGACTCTGACCAATGGGCTGAGCCTGAAGCGGCGCCTGCCCGCCAgcagcttcagcagcagcaacggcgacGAGAGCGACAATCCGCTAGAGAGCAGCGAGAAGCGTGCGCGAAGCAACACGAACGAACTCACGCTGCCCATTGTCGGCAGCAACtga
Protein Sequence
MTLQHSSNTSSSSSTSNNNNSSNSDTVSNSNTNTNNNDVAAGDATIADWKSSSNNNSRYLHKKFKRLASTTETEAAGEPTLRSTSLSSNSSLSPPTQLPLVNGHEHSNSNNHEGESYSKNVAVAGVPRTRTPLSNSSSNNISSSSSNYASNATLSPATFAQHQQQTQPTTTAATAAAAAATVTPAATTASSAAPAATSATAATVTPATGLSRYTCPYCNLICAKPSVLQKHIRAHTNERPYPCETCGIAFKTKSNFYKHCRSRSHAARMRGLDVPAHEADGLSDQDGDGDLSNSSSELLSVEVQSRADSPFDEQSMASLPYIPAYLEQPRVIQPLPLGSPAAGTLPPVTVENLHSATALHRQSIDYKPYKPKFHNAALYAPGSSTEQQQQQQQQQQQQQQQQQQQQQQQQQQQQKLLQPLLVHPTLSPSTQLKLNNHINSHQLQLQLQQQQQHQQQQQQQQQHLQQQQQLLLAAAAGNAVALPPPPLPTGVFYLGQPPYYNPTAAAAMHQHAFALQQLQYQQHYQLQQQQQQHLQQQQHSPLLKVPTQPPPPPPQQQQQQLLPQQLQQQQQQLLPQQLQQQQQQQQLSRSNSQQATVAAAAATPATPTPVGNLSSFASGMQVNVEKVQEHISKLISQNEAIVENKEILLQKKYPKQLNRSRSFNNANNNNGSNSNNSNNSNSNSSSSNQQLGDAKVNLAQSIVQKQQQQQQQQQQQQQQQQVQLQQQQQLQHMQQYRVVEPVNGMLKRSSNSNNAYANVKATPPAAAPAPPAAAAAAMNAKLPSPATMLQLLHYRQDPAMPLNKLEQQQQQQQQVTPAPQPLNLSAKPKPAKPATTAAATTVATAAAAAAIPATSATTTIAAKPATVATAAANNSIIKNLLLNARGLAVPIGEGDDAVYSCPICANEFRSADELKQHNSTYCQDASSSAPISPASSPSSKYFRSNSISLSLPELKSHMANSKNPLSLAKLAWSQLKTKPSSLVLSRLSAAQSPARTSTTATTVAGSSGNNYLAATVANSSSASNSNPTATIASSNNVYSNTHNLPATFAVSIDANNVALRFVDAPLPSPGPLLGKTPLVDYAAPRKAADAQVVITKMHEDRLENIISESSAKRVKLSNESNAFALPASTAAGGVQQLLFNNSQELPGFNTGKEERLRRFTSSGGSMIPISECPELDKSPKMIRTPLLSGGSFQEMSPRLSEPKPKPAFLINASNNSNGNNNSNNSQHFQFPPINSITAFNPLTLPAMSESSSKAIPYVPGIPGPSSLTMLPAPPPPQQLLLPRPPAIDAPPFKKSLSPFGGVQNLPSEFSRQPPTPAQRNALQWQSNSSNKLAATVAAAAGDGLSMQKFNFLRMADNLKEQQQQEVRHFIFDPLHVETPENDGTTAAATSAAAAAAATTAAVTAATSSVAATTSAGTATTVANKTKFLRPTSLPLKPGTFTPKRHHGITPTANTLPLISPETPRPSKSCVQLYLNGHAYTYLGLKCSTKMFYCTVNCPQPSYVAGMHKLSMYSVWQVCEENQPHPLGLKPKQVMSLYDSRQKMFGTGYTVVQAGANAHSYALVGSQQTISSCSTTSSTQSKFYQHQTTKQAPAIGALSEANVAAKANEEAAKKLESGQLLVGGYESNENYTYIRGRGRGRYVCSECGIRCKKPSMLKKHIRTHTDVRPFTCSHCSFSFKTKGNLTKHMQSKTHFKKCIELGINPGPMPADGEFLDVDVEFDQQSSTSAGGRTSSMAGDSADSDDYSDNESESSDTDESKSRLKEHEAARGLLSLSMTPPIPQSVSPYPAQLEASMSAASPANSIGSAGGASTQPKRQVCSFTSPKPPFDYQKQEQYYSNPEESKPKRQVPADESSAPMDLTKPRQIATAAAAAAAATATAATSAAAATVAVVDLPKSQAQQMRDVIFGAGNNECGFMKTLISVSDKVRISAEMEEQAKRESESEDVLLHTYIKEQALHNAKRKQSMYNSSSSSYLMTTTTTSSSSSSSNTTTSSSSSSNMPLVSSSQPKAGLIYHEVPSIEVHEPEPTEIKEPKKEQEPMEQQQQLKAIAVSSQEKQPLEATLAVPAPAPATHNANLPAAVQHPDAIDFKGVLSNSSNTKPIVTTATAAAAATATATATAIVKVLAPEESYKSSSESAAATPTTAAVTATTTASSSSSSGGSGSGYGGRVVPAPPPPIASDARPTCLLCSKTFQRQHQLTLHMNIHYMERKFKCEPCSISFRTQGHLQKHERSEAHRNKVMMTSTFGVPTTSNPRPFECTDCKIAFRIHGHLAKHLRSKTHVQKLECLQKLPFGTYAEIERAGISLTEIDTSDCENSLISLKLLAQKLLEKDPNKLSGYTTPSGMLQLVGAGELPAANQDSASEDGFSAANSAAASAIASLDNDSAGNTPQRASSMSEDETLTNGLSLKRRLPASSFSSSNGDESDNPLESSEKRARSNTNELTLPIVGSN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00510052;
90% Identity
-
80% Identity
-