Dbuz006017.1
Basic Information
- Insect
- Drosophila buzzatii
- Gene Symbol
- -
- Assembly
- GCA_035045845.1
- Location
- JAWNOS010000244.1:199600-204270[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 17 5.6 4.4e+02 1.9 6.9 2 23 346 368 345 368 0.96 2 17 0.0074 0.58 10.9 1.6 2 23 411 432 410 432 0.94 3 17 5.9 4.6e+02 1.8 2.9 2 17 443 458 442 469 0.79 4 17 0.026 2.1 9.2 0.3 3 23 502 522 500 522 0.95 5 17 0.007 0.55 11.0 0.4 1 23 530 553 530 553 0.96 6 17 0.0006 0.047 14.4 0.2 2 23 558 579 557 579 0.97 7 17 0.63 50 4.9 0.0 1 20 587 606 587 608 0.91 8 17 0.00043 0.034 14.8 0.5 1 22 627 648 627 651 0.90 9 17 0.1 7.9 7.4 0.7 1 21 656 676 656 677 0.92 10 17 1.1 83 4.2 1.4 1 23 696 721 696 721 0.96 11 17 0.28 22 6.0 0.4 2 23 737 759 736 759 0.93 12 17 0.0054 0.42 11.4 0.4 3 23 766 787 764 787 0.93 13 17 0.0098 0.77 10.6 0.2 2 23 791 813 790 813 0.96 14 17 1.8e-05 0.0014 19.2 2.1 1 23 819 841 819 841 0.98 15 17 0.0074 0.58 10.9 0.8 1 23 845 868 845 868 0.93 16 17 4.6e-05 0.0036 17.9 2.0 1 23 874 897 874 897 0.97 17 17 0.032 2.5 9.0 0.5 1 23 901 929 901 929 0.94
Sequence Information
- Coding Sequence
- ATGTCGGAAAATTTGAAAgtaaacaatgaaaataagCTTAGCTGCCTGCATTGCAGTGTGTACAATTCAAAGCAGCAATATCAAGAAATTTTCGATGAAGTTGGCATCGAAATTGAACTTGCCGAACTATTAgcgaaatattttcaaatcgTTGTCAAACCTGATTCCCAAAAATCGCAAGTGTTATGCCAAGAATGTGTAAATACGCTAATACGCTTCTTTGACATAGATGAGTTGCAGCGTCAGCAGGATGCCGCTAATGCATCGAAGAAGACTAACCAGCCACCGGTGGATCTGCCAAGTGCCACcaaaaaagtggaaaaaacagataaaaaagcgacagcgacgtcgcCAAAGGCAAAGAGCGTCACTCAGCCAGCCAAAAGTTTGTCAAAACCCGAAACAGTTACAGTCGCTGCTGCGgccgttgttgctgatgttcctgcaactgcagcaaaaagTGTTGATAAAACATTAAGTGATCCGCCCAAACGTTCGCCTATCAAGGCGAAGGAGCTGCCTAAACGAAATGCTAAGGTCAAGGTGAAGAGCCATGGTTCAGCAGATCAGGAACAGATCAGCGCACTCATACGTGACATTCTGGACGATGAGGAGGCGCAGACAGATAGTAAATTTGCCAAAGCAGCAGCCACCGTGCAGAATCTAGAAAAGCAAACGAGCAAAAAGCAGCGACAGCTCGAAACGGAAGAGCAGCAGGGCCAGCTGGAGGAAGAGGATAACAATGATGAGCTGGAGTTTCTATTAGAGCAAGATGACAACTCCTCCGATGCGGGCGTGCGTCATTTCAAAGTGGGGCGTAAACCAAAGCGCGTTGTCTCACAATTTCAATCTCAATCCCtatcgcagtcgcagtcgcagtcgcaaaATGAAAGCCAAAGCGAGGATGAATCGTTTAAAGTGGAAcctttcaattttgttttaattaaagaatCTGACAACATTGGTGATCTGCAAGAATATCTATCGACCGTGATCAAGACCTGTTTTGAGACCTTGCAATTCGATTGGGCCACTGTCTGCCGTCATTGCTCATTTAAATGCCAGAAATATGAAACTTTGCTCAGCCACATGAAGAAAAACCATAAGCTGACCGGTGAACGCTTCCGTTGCCCCATTGAAGGCTGCACGACGGAGCTGCAAGGTGGCAAATATTTGGCCATGCATCTGGTGCTGCTGCATGCACCTGTGGCAGAAATACCCATTTATGGCAAGTGTCCCGAGTGCAATATGACCTTCTCCAATATATtgcaatataataaacattccTGCGCACATGTCATTAAAAAACGACGCGGCATACGTTTATACTGCGAGATGTGCGGCCTGGAATTTCCCTCTTGGAAGCGCTTTAATTTCCacaatcaatttcatttggaGCATCACAGGCCGCGCGCTTGTTTCGTTTGCAATTTTGCAGACAACAATATCGATGAGCTCTTTCGTCATTTGTATTATGCACACGAACCGGATGGCACACTCTTCTGCGATCTCTGTGATCGCAATTTTCGTGATGCTGCCGTCTTTATGGAGCACAATAAATCACATGCGAATGTCAGCAGCACCACCTTCAGCTGCTCGGAGTGCAACGCCAACTTTGAGACACGCGGCCGTCTCAGCGGTCATCTGCGTTATGTTCATGGCAGCGTCATTAGCTGCGAGCTGTGCAGCCGCGAGTTTGCCTCAGAGGCCACATACAACCTGCATATGAAAACGCATTTAATTATTGAGCGTGAAGTGCATGTGTGCAATGGCTGTGGACTGCTCAGCGATAGTAATGAAAAGCTGTTGGCTCACGTGGAGTCGGAGGACTCGGCTTGCTTTGGCTCCGATTTCTATAAGGAATTGTTACGCAATGCTTATGTCTGCGAATATTGCTCAGCGTACTTTAAGCAGAAGAGAGATTTACGTGCCCATCGCGATTCGGGCGTGCATAAGGATGGATATTTCATATGTGAACCCTGTAACAAGGCATTTTCCGAAATGAAACTCTATCGCCATCACTTGCGCAACTTTCAGCAACAGCGCGCGGATCTTTCGCATCGCAAGCTGGAAATATGTCTGTACTATATGTGTGACTATGAGAATTGCTTTGAGTCCTACCTCAACTGGAACTCGCTGTACACACACAAGCGACGTACGCACGATGTCATCGCAAAGCAGGAGCCGCTGGTTAAAAATAACGAATGGATCTGTCAATTCTGTCAGAATCAATATCGATCCAAAATGTCGCTATCGGTGCATGTGGCGCGCAGTCATAATAATAatAATGTCATCTGCCCTCTGTGCAAGTCCTCTTATAAGGATAATGATGCCTTGGCCAAACATCATAGCTATTGGCATGAGCCAATGGAATGTCCACTGTGCttgaaaatagttaaaaatcgTCGCAATTATGATACCCACATGAATGTGGTGCATTCGAATAATAAACGTTACTCCTGCAGCGTCTGTCAAAAGGGATTCTATCATAAGAGTGAAATGGAGGCGCATCAGCGGCTGCATAACCAATCGTATAGCTGCGACAAGTGCAGCTTCGTCACACGGAACAAGAAGTCGTTGTCGGTGCATGTGCTGGGCCAGCATTTCAAGCACTTTGAATTCGAGTGCAAGACGTGCAAAAAGCGCTTCGGACGTCGTCAGGGTCTATCGAATCATATGCAACGTGTGCATGGCTCCAGGTATACGTGCAAGGATTTCTTCGATAGTGGATGCAATATCTCCTTTAGCTCGATGATGCAAGTCAAGTTGCATGTGCGCAAAGCGCATAATAGCAAAATTTACATAGAAGATGAGACGGTTAAGGGCAATGAACTGGAGGAACATGAGCAGGAGgacgagcaggagcaggagcaggaagAGGAGCATAAGCCCGAGGAAGTGACCAGCGATGGTCCATCGACATCAAAGAAACGCTGCATACGCATCAATGCGAATACACAAATCGAGTTTATTGGCAACTCTGCAGAGAATCAGGAGAGGCTGTACGAGGAGTTGCAGGAGGAAAAGTTTACACCGCCCtcgaaaaagagaaaaaagcaaaCTTCAATTAAGTAA
- Protein Sequence
- MSENLKVNNENKLSCLHCSVYNSKQQYQEIFDEVGIEIELAELLAKYFQIVVKPDSQKSQVLCQECVNTLIRFFDIDELQRQQDAANASKKTNQPPVDLPSATKKVEKTDKKATATSPKAKSVTQPAKSLSKPETVTVAAAAVVADVPATAAKSVDKTLSDPPKRSPIKAKELPKRNAKVKVKSHGSADQEQISALIRDILDDEEAQTDSKFAKAAATVQNLEKQTSKKQRQLETEEQQGQLEEEDNNDELEFLLEQDDNSSDAGVRHFKVGRKPKRVVSQFQSQSLSQSQSQSQNESQSEDESFKVEPFNFVLIKESDNIGDLQEYLSTVIKTCFETLQFDWATVCRHCSFKCQKYETLLSHMKKNHKLTGERFRCPIEGCTTELQGGKYLAMHLVLLHAPVAEIPIYGKCPECNMTFSNILQYNKHSCAHVIKKRRGIRLYCEMCGLEFPSWKRFNFHNQFHLEHHRPRACFVCNFADNNIDELFRHLYYAHEPDGTLFCDLCDRNFRDAAVFMEHNKSHANVSSTTFSCSECNANFETRGRLSGHLRYVHGSVISCELCSREFASEATYNLHMKTHLIIEREVHVCNGCGLLSDSNEKLLAHVESEDSACFGSDFYKELLRNAYVCEYCSAYFKQKRDLRAHRDSGVHKDGYFICEPCNKAFSEMKLYRHHLRNFQQQRADLSHRKLEICLYYMCDYENCFESYLNWNSLYTHKRRTHDVIAKQEPLVKNNEWICQFCQNQYRSKMSLSVHVARSHNNNNVICPLCKSSYKDNDALAKHHSYWHEPMECPLCLKIVKNRRNYDTHMNVVHSNNKRYSCSVCQKGFYHKSEMEAHQRLHNQSYSCDKCSFVTRNKKSLSVHVLGQHFKHFEFECKTCKKRFGRRQGLSNHMQRVHGSRYTCKDFFDSGCNISFSSMMQVKLHVRKAHNSKIYIEDETVKGNELEEHEQEDEQEQEQEEEHKPEEVTSDGPSTSKKRCIRINANTQIEFIGNSAENQERLYEELQEEKFTPPSKKRKKQTSIK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00551740;
- 90% Identity
- -
- 80% Identity
- -