Basic Information

Insect: Drosophila buzzatii
Gene Symbol: -
Assembly: GCA_035045845.1
Location: JAWNOS010000180.1:564537-567178[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.0033 0.26 12.0 0.4 1 23 225 247 225 247 0.98

2 7 0.029 2.2 9.1 3.4 1 23 559 581 559 581 0.98

3 7 5.1e-06 0.0004 20.9 0.6 1 23 587 609 587 609 0.98

4 7 7.3e-05 0.0057 17.3 1.8 1 23 615 638 615 638 0.95

5 7 3.2e-07 2.5e-05 24.7 2.9 1 23 644 666 644 666 0.97

6 7 1.9e-05 0.0015 19.1 1.0 1 23 672 694 672 694 0.97

7 7 4.8e-07 3.7e-05 24.1 1.0 1 23 700 722 700 722 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.0033	0.26	12.0	0.4	1	23	225	247	225	247	0.98
2	7	0.029	2.2	9.1	3.4	1	23	559	581	559	581	0.98
3	7	5.1e-06	0.0004	20.9	0.6	1	23	587	609	587	609	0.98
4	7	7.3e-05	0.0057	17.3	1.8	1	23	615	638	615	638	0.95
5	7	3.2e-07	2.5e-05	24.7	2.9	1	23	644	666	644	666	0.97
6	7	1.9e-05	0.0015	19.1	1.0	1	23	672	694	672	694	0.97
7	7	4.8e-07	3.7e-05	24.1	1.0	1	23	700	722	700	722	0.98

Sequence Information

Coding Sequence: ATGGAGCGCAAAGAAGTGGACACACAACAGTTCATCGATCACACGCTACTGGCAACGGAGCTGATGCAAAACAACTTTATGATGGATCTCATGGACACGGGTGTATTTCCGAAAACCGAAGGACCCACCAATCTTAGTACCACCGCGCACCACAGCACCAACAATGGCGGTGGCTATGTGGAAAAGCATACGCTAACACCGCCGGAGCTGAATTTCCACAATACGATCTTCCAGTTCGTCAACAAACATGTTGTCGAGGAGCCGAATAGAGCGCAAACGGATGCTGTACCCGCTTCCCCAGAACGCACGCCCAACAACTATGTCAAAGATACGGACGTGGAGTTTCTTACACTCAACAGCAGCTTCTTGGATCGGGCTGATGCGGCTGAAACTGCTGCAGCCGGGGGTAACGAGAATGTGGTGCCACAGCAGGTGGTTCCACAGCCCACTTTTCCCGCACTGGCCATTGAACCGACTGTGCCGATTGATGTGAATGCAGCGCTTCATGGCGACGATTTACTCTATGCCCACAATGCATCCGTAACAAACGCACGCAAAGTTTTGCCCCACAAGAAACGCATCTCACGCAAGCTCAAGGGCTCCGTGTGTGGGCTCATGGAGGCCGAGCTGGAGCAGCACAAGCATCAGCATGTTGTGTCCACTGTGGCCAACTATAGTTGCGAAATATGCGGCTATGCCGTGCACACACAAATCGAATTTTATGCACATCTAAAAGAGCACTACGATCCGGGCAGTCTGCAGCAGCGTCTAGATgtgccacaacagcagcagcagcagcaacaacagcaaaaggaGCCGCTGGACATGTGCGGCTTGTCTGCGCAGGATAAGCAGGAGCAGGCCAAACTGGATCAAGTATTTCAGGATGTGCAGCTGAATTTTGAGAACTTTCACAACATTAGCCATGTGGATGATGACGTGGTAGACGATGTGGGCGTCAATATGGTCATACATTCGGATGCCATGTCATTGCATAAGGCCGATGACAAACTGACGCCCGTTGGAGCAGCGAATACAACTGCAACGAATCCAGTTGTGGATGATGTGGAGTTCAGTGATACGGAAGATATGCTGGAAGGCATACGCAACGTGGTGGACAAGGTGTCCGTTGAGGATACCTGCGATGCACCCTGGTTTAACAACAATTTCAGTGATATTGCCTTCGcagggctgctgctgccaggcGAACCGCCGCCGCCAGCGCCTCCAACAGCACCTACTCCTCCAGCTACAGCACTGCTCAAGCCGTCAAATCACATGGAAGAGCACCAGCAGAATGAGCAACTAACGTTGAATTTCCTAAAGCAATCCACACAGCCCAAACTGGAAATGGGTCACAAGAAGAGCTACATTGAGGCAATCGCTGCAGCAGAAgccgcggcagcagcagcggctacAATGACAAATGCGACCTCAATATCATCTCCCAGCCGTACGCCAACGCCCAACGCTGGCTCCACCATTGAGCAGCTACAGCGTTCGCCTCTAATGCTCAGTGAATCCTTTAAGTTGGAGGATGTGGAGGCTACAGCGCCCATAGGCAGCGCCAACTCGTCACCAGCGGCCAACGACATCATCGATGACAATGCGGATAGCTTTCTCATGGAGGAGGACAAGCCGCCTGTCGATGAGCCCAGCGATGCCAAGCGCAAGTTTCACTGTGAGACTTGCGCTCGagattttaattcatataatgCGCTCAAGTATCATCAATATACGCACACCAAGGAACGCGCATTTCCGTGCAGCACCTGCGCACGATCCTTCTACACGCAGAGTGCACTCAAGGCGCATGAACGAACCCatTCCGGCGTGAAGCCGTACAAGTGTGAGAAATGTGATTTCAAGTTCCGGCAATGGGGCGATCTCAATTACCATTTCATCTCGCGTCACAGCGAGGTGAAAGCGCACATGTGTGAATATTGCGGAAAGAGTTTCTCCCGGAAGTACTCCCTGGTGCTGCACCGACGCATCCACACCAGTGAACGCAACTATGCGTGCCAGTACTGTACGAAAACGTTCCGGGCCAGCTCCTATTTGTTAGCCCACACCAAAGTGCATACGGGCGAAAAGCCGTATTCGTGCAGCGTATGCGATAAGAAGTTTCGTGTATCCGGCGATTTGAAGCgtcacacacgcatacacgaTCCGGCACGCTTGGGCCAAACCACCTCGGAGTCGGCGACAAAGAAACGCAACAATAAACTGAAGCAAATTGAGGATGAGGATGTCGAGGCGATCATCAAAAACAAGTCTGATACCCTGTGCGGCGATGCAGAGCAGGAAATTTTGGGCTTATAA
Protein Sequence: MERKEVDTQQFIDHTLLATELMQNNFMMDLMDTGVFPKTEGPTNLSTTAHHSTNNGGGYVEKHTLTPPELNFHNTIFQFVNKHVVEEPNRAQTDAVPASPERTPNNYVKDTDVEFLTLNSSFLDRADAAETAAAGGNENVVPQQVVPQPTFPALAIEPTVPIDVNAALHGDDLLYAHNASVTNARKVLPHKKRISRKLKGSVCGLMEAELEQHKHQHVVSTVANYSCEICGYAVHTQIEFYAHLKEHYDPGSLQQRLDVPQQQQQQQQQQKEPLDMCGLSAQDKQEQAKLDQVFQDVQLNFENFHNISHVDDDVVDDVGVNMVIHSDAMSLHKADDKLTPVGAANTTATNPVVDDVEFSDTEDMLEGIRNVVDKVSVEDTCDAPWFNNNFSDIAFAGLLLPGEPPPPAPPTAPTPPATALLKPSNHMEEHQQNEQLTLNFLKQSTQPKLEMGHKKSYIEAIAAAEAAAAAAATMTNATSISSPSRTPTPNAGSTIEQLQRSPLMLSESFKLEDVEATAPIGSANSSPAANDIIDDNADSFLMEEDKPPVDEPSDAKRKFHCETCARDFNSYNALKYHQYTHTKERAFPCSTCARSFYTQSALKAHERTHSGVKPYKCEKCDFKFRQWGDLNYHFISRHSEVKAHMCEYCGKSFSRKYSLVLHRRIHTSERNYACQYCTKTFRASSYLLAHTKVHTGEKPYSCSVCDKKFRVSGDLKRHTRIHDPARLGQTTSESATKKRNNKLKQIEDEDVEAIIKNKSDTLCGDAEQEILGL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00509989;
90% Identity: iTF_00551751;
80% Identity: -