Dbuz002008.1
Basic Information
- Insect
- Drosophila buzzatii
- Gene Symbol
- -
- Assembly
- GCA_035045845.1
- Location
- JAWNOS010000062.1:2528217-2530814[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.075 5.9 7.8 5.9 3 23 265 285 263 285 0.96 2 12 0.012 0.92 10.3 0.4 1 23 291 316 291 316 0.92 3 12 0.0051 0.4 11.4 0.7 2 23 324 348 323 348 0.93 4 12 0.00027 0.021 15.4 2.0 1 23 360 382 360 382 0.98 5 12 2.6e-06 0.0002 21.8 0.2 1 23 389 411 389 411 0.98 6 12 0.0074 0.58 11.0 0.1 1 23 417 439 417 439 0.98 7 12 0.0071 0.56 11.0 4.0 1 23 445 468 445 468 0.98 8 12 0.0097 0.76 10.6 3.9 1 23 474 496 474 496 0.96 9 12 0.00016 0.013 16.1 3.6 2 23 503 524 502 524 0.96 10 12 4.3e-05 0.0034 18.0 0.3 1 23 638 661 638 661 0.96 11 12 0.011 0.89 10.4 1.2 1 19 667 685 667 689 0.94 12 12 4.1e-07 3.2e-05 24.3 3.2 1 23 695 717 695 717 0.99
Sequence Information
- Coding Sequence
- ATGAATGAGGGGAGTGAATACTCCATACAAACAATATGCCGCATTTGCTTGAATCATTTGCGAAACGATGCCGCCTACGATTTGTTTTTGGTCCCTGGTCTGGCCAAGAAACTTTGCGTGTGCACATCTCTCTCTGTGGAACAGCACGATGGTTTCCCGATGAATCTGTGCACCAATTGCTACACCCGGCTTAACGACTTGCACGACTTTCAGAAGCTTTGTGTTGACTCCGTACAAAGGTTTCAGGAAATGGTCGCCAATAATTTCTTTACACCAGCAGCGGCGTCAGCTAACCAAATCAACAACTTTGATGTGCTGAATGTTGCTACACAGGAGGGAGATTTGGTTGGCGAGGACGAGGATCGCATTAACTATGATCCGTTGCTGAATCACAAAATGGAGATTATAGAGAATGAAGAGGATGTTTTCAAAATGTTAGAGCACGTTGACAAAGAGGCAGAGGAGGTTGAGAAGGAAGTCAAACAGGATGTGGAAGAGCAGTCTGGTGTTTTCCAAATGTTCGGCGATGATTCTTCAATGGCAAGCAGCAACGAGAACGACAATGACATAGACTTTGAGCCAAACAGCACGGATGGCGACGACGATATGCCCCTTGCTCAACGATTACGTGGTAATCCCAGGAACATTAGCAAAGCTGTAACAAAAAGAGCTTCTGACAGTGTGGAATTGGAAGATGACTACAGTTCGGCATCGGATGAGAATGGTTCTAAGTCGAGAGTTAAACGCAAGCGAATACCAGCAGCTGAACGGCATTTGCATCGCATCATTGACTGTCACATCTGCCATCAGAAGTTCAAGAAGGCAATTCGGTACGAGGAGCATATGAAGCATCACAATGATCTGTTACCGTTCCAGTGCAAAGTTGAATCGTGCAGGAAGGGCTTTACGACGGCCGGTGGACTGCGGCTGCACGTGGACCATGCTCATACGGAACTGTCCGAGGTGCACGCCTGTAGCATCGAGGGATGTGGCAAGACGTTTCCTCGCATTCGCCTGCTTACTTTCCACATGAAGAAGGTGCACAACATTTCAAAGGCAGCTGCGCCACCCAGAGACTATCCCTGCACGGAGTGCGAAAAGGTGTTCCGTTGTCCGATGGCCCTGAAAAAGCATATGTATAAGCACGACGGCAAGGAGCTGCCGTTCCCTTGTAATATATGCGGCAAACGCTTCGTGATCAACAGCGCGCTCAAAGATCATCTAATGCGGCACGCTGGCATCAAGAACTATGTGTGTCCCTACTGTGGAGTAGGCAAGACCACACGACAGGAGTGGAACACTCATATCCTAACCCACACCCAGGAGAAGAAGTTCAAGTGCCATATATGCGAGCATGCGTCGCATAACAAGCAAAGCCTGGCTAACCACATCAAGATTGTGCACGAGAAGATTAAGAACTATGCGTGTCAGTATTGTGGTAAGACCTTTGGGAAGTCGCACGCCTGCAAGATTCACGAGATGACGCACACGGGCGAAAAGCGTTGCGAGTGCAAGGTCTGCGGCAAGAAATTCCTTTATCCAAAGAGCCTCACCAAGCATTTGAAGACGCACGAGAAGCGTGTGCTACGCGCCATTGAAACGTATCGCCAGCGGCAAGTGGAGTTGGGAGAAGTTCCAACGAATAGCGCTGAGCCAACGGATATAGCGGATGCTGTTGCAGCCGCTGAGACCCCCACGCCGACGGATGGAGTTGATATGATCATTTCTCAAAATGCGGCTGATGAACTACTTAAAGTGTGCGCCGAATCGGTGGCCACGATACCCAAAGATCCGAGGCGAGTGCAGCGTGTGGACATTGCGCAACTAGCCGGCACTGCCGTCAATCCAATTCCGTCTGTGTCTGTTCCATCCTGGTCGCCCCAAGTGAACTTCACTAAGAAGGAAGGCAAGCACATTTGCCCCGGTTGCGGGCAGGGCTTCAACAATATCGGCAACATGAAACGGCACTACAAGATCATACACGAGAAGGTCAAGGATTTCGCCTGTCGTTTCTGCCCCAAGCGCTTCGCAAAGGCTCAGACATTGCGTCATCACGAGTGGATACACACGGGCGAGAAGCCGTTCGAGTGCAAGATATGTGGCACACACTTCCGGCAGGAGACGGCGCTGAAGCGACATCAGAGAACGCATGAAAATCGCCCACCCGTCATCTCATCCAAGTTTTATGCCGCGCGCGAGGAGTTGGAAGAACAGGAGCGCACAAAGTGCGAAGCCAGGCGCAAGGCGGAGGCGAAACGCAAGGAAATAGCAGAGGCCGCTAAGGAGCAACTCTCGTCCCTGCACAAGATTGAGGCCACCGACAAGAATCTGCACTCGTATGACGAGTACCAGGAGGCTGCTGCAGAGCGAGCAGCTGCTTCGGCTGAATTGCAGGCCCAACAGTTTGAGGAGAATGAATTAAAGCGGCGGGCTGACATGGAACGGCTCAAAATACAAGAAGCCGCTTATGAGCAGCTGCAGAAGCTACAGAAGCAGCAGGAAATCGAAAAGGCGCAAAGCTCCTACGATGGCTACTATGCGCAAAAGGCCAATGCCGATGGCACCAACCTGGAGGATCTGAAGCTAGACCACGTGTGA
- Protein Sequence
- MNEGSEYSIQTICRICLNHLRNDAAYDLFLVPGLAKKLCVCTSLSVEQHDGFPMNLCTNCYTRLNDLHDFQKLCVDSVQRFQEMVANNFFTPAAASANQINNFDVLNVATQEGDLVGEDEDRINYDPLLNHKMEIIENEEDVFKMLEHVDKEAEEVEKEVKQDVEEQSGVFQMFGDDSSMASSNENDNDIDFEPNSTDGDDDMPLAQRLRGNPRNISKAVTKRASDSVELEDDYSSASDENGSKSRVKRKRIPAAERHLHRIIDCHICHQKFKKAIRYEEHMKHHNDLLPFQCKVESCRKGFTTAGGLRLHVDHAHTELSEVHACSIEGCGKTFPRIRLLTFHMKKVHNISKAAAPPRDYPCTECEKVFRCPMALKKHMYKHDGKELPFPCNICGKRFVINSALKDHLMRHAGIKNYVCPYCGVGKTTRQEWNTHILTHTQEKKFKCHICEHASHNKQSLANHIKIVHEKIKNYACQYCGKTFGKSHACKIHEMTHTGEKRCECKVCGKKFLYPKSLTKHLKTHEKRVLRAIETYRQRQVELGEVPTNSAEPTDIADAVAAAETPTPTDGVDMIISQNAADELLKVCAESVATIPKDPRRVQRVDIAQLAGTAVNPIPSVSVPSWSPQVNFTKKEGKHICPGCGQGFNNIGNMKRHYKIIHEKVKDFACRFCPKRFAKAQTLRHHEWIHTGEKPFECKICGTHFRQETALKRHQRTHENRPPVISSKFYAAREELEEQERTKCEARRKAEAKRKEIAEAAKEQLSSLHKIEATDKNLHSYDEYQEAAAERAAASAELQAQQFEENELKRRADMERLKIQEAAYEQLQKLQKQQEIEKAQSSYDGYYAQKANADGTNLEDLKLDHV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00575777;
- 90% Identity
- iTF_00546820;
- 80% Identity
- -