Basic Information

Insect: Drosophila buzzatii
Gene Symbol: Zbtb41
Assembly: GCA_035045845.1
Location: JAWNOS010000532.1:108036-109733[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 5.8e-05 0.0045 17.6 1.9 1 23 93 115 93 115 0.97

2 11 2e-07 1.6e-05 25.3 2.8 1 23 121 144 121 144 0.97

3 11 9.2e-06 0.00072 20.1 1.2 1 23 150 172 150 172 0.98

4 11 6.1e-05 0.0048 17.5 0.8 1 23 178 200 178 201 0.95

5 11 1.6e-06 0.00012 22.5 0.9 1 23 208 230 208 230 0.97

6 11 0.00084 0.066 13.9 1.2 1 23 236 259 236 260 0.95

7 11 0.0072 0.56 11.0 0.2 3 23 267 287 265 287 0.96

8 11 2.1e-05 0.0017 18.9 2.7 1 23 293 315 293 315 0.98

9 11 1.9e-05 0.0015 19.1 4.7 1 23 321 343 321 343 0.99

10 11 0.0024 0.19 12.5 1.3 1 23 349 374 349 374 0.95

11 11 0.00069 0.054 14.2 0.2 1 20 380 399 380 401 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	5.8e-05	0.0045	17.6	1.9	1	23	93	115	93	115	0.97
2	11	2e-07	1.6e-05	25.3	2.8	1	23	121	144	121	144	0.97
3	11	9.2e-06	0.00072	20.1	1.2	1	23	150	172	150	172	0.98
4	11	6.1e-05	0.0048	17.5	0.8	1	23	178	200	178	201	0.95
5	11	1.6e-06	0.00012	22.5	0.9	1	23	208	230	208	230	0.97
6	11	0.00084	0.066	13.9	1.2	1	23	236	259	236	260	0.95
7	11	0.0072	0.56	11.0	0.2	3	23	267	287	265	287	0.96
8	11	2.1e-05	0.0017	18.9	2.7	1	23	293	315	293	315	0.98
9	11	1.9e-05	0.0015	19.1	4.7	1	23	321	343	321	343	0.99
10	11	0.0024	0.19	12.5	1.3	1	23	349	374	349	374	0.95
11	11	0.00069	0.054	14.2	0.2	1	20	380	399	380	401	0.95

Sequence Information

Coding Sequence: ATGGTCCGCAACCGTCGCAGCCTCTCCAAAGAGGATGCCGTCTCTCTGCTCACGGATAGCGGTATTTCGTTGTCATCGCCGCCGGCGGCGCGTGAATCCTCGCCTGCTGCGCCGGCCATTAAGCGCCGCAAGAGCAGCCTCAACAGCAGCTTGCAAGATTTGGATGTGGATAGCGAACAGGAATCTGAGCAGGACTCAACAGACACAGATACTGACTACATTCAGCCGCAGCCAAAGAAATTACGACGCAAGACAGAGTCCTCCAAACGCAAGCAACACGTGTGCAATCATTGCTCGAAGGAGTTCGGGGGCAACACCGACTTGCTACGCCACATGCTCATCCACTCGGATGAGCGACCACACAAGTGCACCGACTGCGGCAAATGCTATCGCCAGGCAGTGAACCTTAAGAATCACATTATCACCGCCCACGAGCACAAGAAACAATTTACATGCACGCAGTGTCCCAAGTCGTTTGCACTCAAGGAGCGCCTCAAACTGCACATGCGTCTGCATTCGGGTGAGAAGCCATATTCATGTGCTCTGTGCGAGAAACGATTCGCACGTGGCGGCCAACTTCAGCAGCACATGGTATCCCACCACAAGATGAGCATCCAACAATTCAACTGCACCAAGTGTTCGGCCAGCTTTTCCACCAATGCCAATCTGCGCGTGCACATGGAGCGTCACGATCAGGGTATGGAGCACAGATGCACCATATGCGAGACTCAATTTGCCACTGAATTGGCACTACGCGCCCACATCAATCAGGAGCACCACAAGCTGAGCCAACTCGACTGTGAAATATGCCATAAGACCATCGAGCCAGATGAGGATCTGGCCACGCACATGCAGAAGCACGCTCCGGTTAAGACGCACGTCTGCGAGGTGTGCAATTCGTATTTTACGCAAAAGTCGCAATACAATGTGCATATGCGAATGCATACAGGGGAGCGGCCGTATCAGTGTCGGATCTGTCATCAAACATTCGCCCACTCCAGCGTGCTGAAGCTACACATTCGCAAGCACACGGGAGAAAAGCCATTTCGCTGCCAGCTGTGTACGGATGAGGTGGCCTTCTCGCAGCTTGCACATCTCAAGAATCACATGAAGAAGATACACAAGCAGCAGAAACCGTACATGTGTCCCGGTTGTCACGAGTTCTTCAAAATCAAGGTTGAGCTGCAGGCGCATACCGAACAGTGCACAAAGTGCAAAGCCATGGGAGAACCCAACGATAGTCAGGCCGAAGATGCCCATACACTATCCAACATTCGCTTTAACATTGCCGTTGTGTTGAAGAAGATAACCTCAGCGCAGAAGCTGCGCCAGCTGGGCTACGAAAAGCGCTTGATTGATAATGTCATCATAGCATCCCTCAAGCTGGCTCAGCGTCCGTCACACGACGACCCAAAGCTAACGCCTTTGGCTAGGCTGCGCTTAAATGTGGAGGAGTTTCTCAAGTGGATTGTGCCGCCGCAGACCATGCAGAAATTCAGTGAGGAGCTGCTCTCGATCGATACGATACTCGACAAGATTGCGACCATGTACATGAACCAGAAGTAG
Protein Sequence: MVRNRRSLSKEDAVSLLTDSGISLSSPPAARESSPAAPAIKRRKSSLNSSLQDLDVDSEQESEQDSTDTDTDYIQPQPKKLRRKTESSKRKQHVCNHCSKEFGGNTDLLRHMLIHSDERPHKCTDCGKCYRQAVNLKNHIITAHEHKKQFTCTQCPKSFALKERLKLHMRLHSGEKPYSCALCEKRFARGGQLQQHMVSHHKMSIQQFNCTKCSASFSTNANLRVHMERHDQGMEHRCTICETQFATELALRAHINQEHHKLSQLDCEICHKTIEPDEDLATHMQKHAPVKTHVCEVCNSYFTQKSQYNVHMRMHTGERPYQCRICHQTFAHSSVLKLHIRKHTGEKPFRCQLCTDEVAFSQLAHLKNHMKKIHKQQKPYMCPGCHEFFKIKVELQAHTEQCTKCKAMGEPNDSQAEDAHTLSNIRFNIAVVLKKITSAQKLRQLGYEKRLIDNVIIASLKLAQRPSHDDPKLTPLARLRLNVEEFLKWIVPPQTMQKFSEELLSIDTILDKIATMYMNQK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01324297;
90% Identity: iTF_00534722;
80% Identity: -