Basic Information

Insect: Drosophila busckii
Gene Symbol: ci
Assembly: GCA_011750605.1
Location: NC:275737-284058[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 0.01 0.6 10.2 0.6 3 23 493 516 491 516 0.94

2 5 0.074 4.4 7.4 0.2 1 23 524 551 524 551 0.84

3 5 0.00013 0.0081 16.1 2.9 1 23 557 581 557 581 0.98

4 5 0.00024 0.014 15.3 0.4 1 23 587 612 587 612 0.97

5 5 9.9e-06 0.00059 19.6 0.3 1 23 618 643 618 643 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	0.01	0.6	10.2	0.6	3	23	493	516	491	516	0.94
2	5	0.074	4.4	7.4	0.2	1	23	524	551	524	551	0.84
3	5	0.00013	0.0081	16.1	2.9	1	23	557	581	557	581	0.98
4	5	0.00024	0.014	15.3	0.4	1	23	587	612	587	612	0.97
5	5	9.9e-06	0.00059	19.6	0.3	1	23	618	643	618	643	0.96

Sequence Information

Coding Sequence: ATGGATGCTTATGCGTTACCTACGTATTTTCCGCTGGCCTACTCGGAGTTGCAGTTTTTAGCATCGAGAAGagctgcggcggcagctgccGCAGCTACAGTGTTGCCATGTACACCCTCTAGAAATCATGGACATATGCATACTCATCACCATCCTCATGCTTCGGATGTTAGCAGTTCAGTTTCAATAGCTACAAGTGCTTTAGATTCAACGTCCGCCACAAACGGTAGGTCCAACGATGTCCTCACTGTGGTGAATAATGCTGTCCAGGGCGGGCAAGGCCAAGAACAAAGCCATCATCATCACACGCATGCTCTTGATCATGTAGGAGTTACTGTGACTTCGCAACCACAGACACACGACTTTCATCCGGCTTATAGAATCCCGGGATATATGGAGCAGTTCTACTCCTTGCAACGTAGCAGCCCGACTGCGTCCTATCACGATCCATATACGAATTGCGCACCAGCCTTTCATTTGGCTGGGCTGGGACTGGGCTCCAGTGAGTATTTGAGCGCACGTGGAATGGGTTCATTGAGTGAACTTCATCATGCTGCtgtagcagctgcagcagctgcggctgctgctggatcTTTAGCAAGCACCGATTTTCACTTCAGTTTTGATGGAAATGGTCGCCTTAACAGTTCTCGTACGGCTGCAACTGCCGCTGCGGCTGGGGCAGGAGGAAGCATCCGTGCTAGTGTTAGCCGGAAGCGTGCACTTTCCTCATCACCATATTCAGACTCTTTTGACATTAATTCAATGATTCGTTTTTCGCCGAACTCGCTGGCAAACATGATGAGCGCGTCGCGTGCCAGCAGTGCAGCGAGTGGCTCATATGGCCATTTATCCGCGGGTGCCATAAGTCCTATTGGTATATCGCATGCGCACTCTGCCATGACGCCtcatttgcagcaattgcaggcTCATTTGTTACGCGCTAGCGCTGGACTCCTGCATCCAATGACGGCCCAgcaagcggcagctgctgccagttaCTCAATGGGACATGTCGCTAATGCCGCGGCGCTCGGTCTAAGCGAGGTCTGTATCAATGCTAAGGATGTGGCCATGAGCAGTCAAGTCTCCACGCCAACGCCTACCCCCACGCAGACGCCTACGTCGACATTCTTGAGTGTAACCACAGCAGACGAGTCAATTATTAAGGCCCCACATAATTCTAAATCCGTCAAGAACTTTCACGATGTAAGCAGTGAGCGATTCAGTCGACTGGGCAAGATTAAGCCATCCGAGCAACCGTCATCAACTTCGGAGAGTGTTGCTCAGGTCGAGGCTGACAGCGCCTCTTCGAATGTGCACGATCGTGAAAAGGGCCGTCAGAGACTTCATCATCATGATACCTTCGATCATGAACAATTAAGTTCCATATCAAATCCACTAAATGAATACGATTGCACCACAGCAGACACCACAGATATTAAGGACGAACCAGGTGATTTTGTCGAAACTAACTGTCACTGGCGTAACTGCAGCGTAGAATTCATAACCCAAGATGAACTGGTGAAGCACATAAATAACGATCACATTCAAAGCAACAAGAAGGCATTTGTCTGCCGTTGGGAGGATTGCTCACGTGGCGAAAAGCCTTTTAAAGCCCAATATATGCTTGTAGTACATATGCGTCGTCACACTGGCGAAAAGCCTCATAAATGCACTTTTGAAGGTTGCTATAAGGCTTATTCGCGCTTGGAAAATTTGAAAACTCATTTACGTTCGCACACGGGTGAGAAGCCTTATACCTGCGAGTATCCGGGCTGCAGTAAGGCCTTCAGCAATGCTAGTGATCGTGCCAAGCACCAGAACAGAACCCACAGTAACGagaAACCGTACATTTGTAAGGCACCCGGGTGTACAAAGCGATATACAGATCCGAGTTCACTTCGGAAGCATGTGAAGACTGTACATGGCGCAGATTTCTACGCAAATAAGAAGCACAAAGGATTGCCTTTACATGATGGCAATTCTGGACTCGATAGGGAGAGCAACAGCCAGCATATGCATCGGCAACAGTTACAAGAACAGCATATAGACTCGAGTCCGTGCAGTGATGATTTTAACTCTGGTAACGCGATCGGTAATAGTCCAAGCGTCAAGTCCGAGTCGGGCGCCAATTCCCCAGCCCAATTAAACGTTGGCTCTACAAATCCCTCCGATGGATCTTTAATGTTCCTCAATAACGGAAGGCATGGTGAGGGCAACTTAGTTGGCGATACCGCGCCCTCGCTGGATGATGGTTGGCCCTATGATGATGACATAGATGCTGCAGATCTGCCAATTGTTTTGCGCGCTATGGTTCACATTGGTAATGGAGGAAATACAGGGGGTGGGTCTCTTGGGGGCGCTCATGGCATTGGGCGTCAGCGCTTCCGCAGTCGCCTCCAGACTAAAGTAATCAACTCTACCAACTCCATGCTTTCAAACATACCCGAGAGCAATCGTGTAATAGGCATCAGCGAGCTAAATCAGCGCATAACCGAGCTCAAAATGGAACCGGGCATCACTGCTTCTTCTGGGCTGAGTGACCTTCACGTATCCCATTGCCGATCGTCAACGCAtttgaaacagcaacaattacatcTACAACAAAGCTGTAACTCGTATGGAGGAGTAGGAGCACAGTCACAATCGCGCCGAGATAGTCAAAACTCCAATGCCAGTACCTATTATTGTAGCATGCCAAGTCGTCGAAGCAGTCAGTCCTCACAGCTGTCATCCATATCGACTATGCGCCCTGCTGGTTGTCCTTTGTATAGCACGACTTCAGGTTCAACGAGTGTTTCTCTGTACGACCCCATATCACCAGGTTGCTCTCGTCGCTCAAGTCAAATGTCGAATGCTCAGTCTAATATAAGTCCAAACATGCAATGTGGTATGCAGTGCGTAGATACGCAATATCCATCCAGCTCTCACACAGATATCCAAACGTTCTACAATCGACTATCTAATGATCAATGCCAGACACAGTACCTGGGATCTGCACCTCCGATTATGTCTGGCAACAGCACCAGTCTACCGCCGCCGCCTTCATCTCACGTAATTGCCACACATctacaacagctacaacattCAACAAGTGTTCAACTTCAACATAGGGGGTTGCCTGGGCGTTATTCAATTCCGAATTCTCCCACCTCAAACTCTACATATGAGCAGACAGATCAGTTGGTGCCGCAGTCGCAATTGCAAAACAGTGTACATTTGAGACGCCAATCGGAACCAATTTTAGCTCAGCAGACCTTGGAGCGCATGGGTGGAATTATGCCTGCTTTTCATAGGCTGGCTAGGGAATGTCCCATCCCATCAACTGTATCGCCGGCCAAGGCTAGTTTAGCTATAAGCAGTGCGCCGGGAGTGAGCGTGGCTAATTCACGTGACCATCACCCCAATGAGAAGGTTGATCTAGATAAAGTTGAAGAACTAATTTTACCTGATGAGATGCTCCagtacttaaatttatttaaggaTGCTGAAATTACAAAGACCAATCCACCGACAAGTAACGGATCAACAATGATCAAGCCCACTATATCATTTGCACCCACGGCCCCATCCGAAACCGCACATTACGGCCCATCTCCCATAACACAGACGATATCGCCCCCATGCGCTGAGCGGAGCAACGTTTCTGGTGTACCAGACAATGCGTATCATCAAACTGCAAATATTGAGAACACAAAAGCACCTATGAATGATCAATATACATATCGCTATGCGCAAGAGCGTGATCGAACAGGTACagtagcagcaaaagcagGACCTCAATTTGAAACGCCACTAAGGGATCAAATTATTACTGATTCTTCAATGACGAGCCTGCCAGAGCTGTCTATGCCTGCAGATGCTGATCAGAAACAGAAGCAAAATAGCGCAAGCGAAATCCAATGCGGAGTTGTCAGCCAATCACAGATGTCACCGGCTATAAAGATGGGTGCAAATGGTACGAATCAATGTATTCCGGCTGAGGACAAGAGCTCTGGAAATGAATTGAGAAGTCAATGTATCAAGTCTTTCCAAGAGGGTGATAATTTGCCATCTATGCAGTCAGACACATATCAGCGCACACTAGAGTATGTACAAAGCTGCCAGAATTGGATGGAGACCAACAGTAGTTCTTTGTCAACGAGTCATACTCCTGTTTGGGCCGATGTAACCAGCTCGACGCACCCACATCCGCACGCCTCTCCATATCCACAAGCACATACCGGCAATAATATGATTATAAATGATATGACTACATCGTTAAGCTCCCTTCTGGAAGAGAACCGATATTTGCAGAtgatgcaataa
Protein Sequence: MDAYALPTYFPLAYSELQFLASRRAAAAAAAATVLPCTPSRNHGHMHTHHHPHASDVSSSVSIATSALDSTSATNGRSNDVLTVVNNAVQGGQGQEQSHHHHTHALDHVGVTVTSQPQTHDFHPAYRIPGYMEQFYSLQRSSPTASYHDPYTNCAPAFHLAGLGLGSSEYLSARGMGSLSELHHAAVAAAAAAAAAGSLASTDFHFSFDGNGRLNSSRTAATAAAAGAGGSIRASVSRKRALSSSPYSDSFDINSMIRFSPNSLANMMSASRASSAASGSYGHLSAGAISPIGISHAHSAMTPHLQQLQAHLLRASAGLLHPMTAQQAAAAASYSMGHVANAAALGLSEVCINAKDVAMSSQVSTPTPTPTQTPTSTFLSVTTADESIIKAPHNSKSVKNFHDVSSERFSRLGKIKPSEQPSSTSESVAQVEADSASSNVHDREKGRQRLHHHDTFDHEQLSSISNPLNEYDCTTADTTDIKDEPGDFVETNCHWRNCSVEFITQDELVKHINNDHIQSNKKAFVCRWEDCSRGEKPFKAQYMLVVHMRRHTGEKPHKCTFEGCYKAYSRLENLKTHLRSHTGEKPYTCEYPGCSKAFSNASDRAKHQNRTHSNEKPYICKAPGCTKRYTDPSSLRKHVKTVHGADFYANKKHKGLPLHDGNSGLDRESNSQHMHRQQLQEQHIDSSPCSDDFNSGNAIGNSPSVKSESGANSPAQLNVGSTNPSDGSLMFLNNGRHGEGNLVGDTAPSLDDGWPYDDDIDAADLPIVLRAMVHIGNGGNTGGGSLGGAHGIGRQRFRSRLQTKVINSTNSMLSNIPESNRVIGISELNQRITELKMEPGITASSGLSDLHVSHCRSSTHLKQQQLHLQQSCNSYGGVGAQSQSRRDSQNSNASTYYCSMPSRRSSQSSQLSSISTMRPAGCPLYSTTSGSTSVSLYDPISPGCSRRSSQMSNAQSNISPNMQCGMQCVDTQYPSSSHTDIQTFYNRLSNDQCQTQYLGSAPPIMSGNSTSLPPPPSSHVIATHLQQLQHSTSVQLQHRGLPGRYSIPNSPTSNSTYEQTDQLVPQSQLQNSVHLRRQSEPILAQQTLERMGGIMPAFHRLARECPIPSTVSPAKASLAISSAPGVSVANSRDHHPNEKVDLDKVEELILPDEMLQYLNLFKDAEITKTNPPTSNGSTMIKPTISFAPTAPSETAHYGPSPITQTISPPCAERSNVSGVPDNAYHQTANIENTKAPMNDQYTYRYAQERDRTGTVAAKAGPQFETPLRDQIITDSSMTSLPELSMPADADQKQKQNSASEIQCGVVSQSQMSPAIKMGANGTNQCIPAEDKSSGNELRSQCIKSFQEGDNLPSMQSDTYQRTLEYVQSCQNWMETNSSSLSTSHTPVWADVTSSTHPHPHASPYPQAHTGNNMIINDMTTSLSSLLEENRYLQMMQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -