Basic Information

Insect: Drosophila busckii
Gene Symbol: -
Assembly: GCA_011750605.1
Location: NC:2423314-2427450[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 2e-05 0.0012 18.7 0.1 1 23 138 161 138 161 0.96

2 15 0.0011 0.064 13.2 2.9 2 23 210 232 206 232 0.89

3 15 0.0091 0.54 10.3 0.8 1 23 317 340 317 340 0.93

4 15 0.17 10 6.3 3.4 2 23 389 411 388 412 0.95

5 15 0.00073 0.044 13.8 0.2 1 23 471 494 471 494 0.94

6 15 1.5 89 3.3 0.1 2 14 513 525 512 537 0.85

7 15 0.00024 0.014 15.3 2.7 2 23 545 567 544 567 0.96

8 15 9.9e-05 0.006 16.5 0.1 1 23 635 658 635 658 0.95

9 15 0.0002 0.012 15.5 0.2 1 23 706 729 706 729 0.93

10 15 0.00048 0.029 14.3 2.3 2 23 779 801 778 801 0.97

11 15 0.0059 0.36 10.9 1.7 1 23 882 905 882 905 0.92

12 15 0.039 2.3 8.3 1.5 1 21 957 977 957 978 0.95

13 15 0.05 3 8.0 0.2 2 23 1032 1056 1031 1056 0.86

14 15 1.7 1e+02 3.2 0.7 1 20 1075 1096 1075 1099 0.63

15 15 8.5 5.1e+02 1.0 0.4 14 23 1126 1136 1124 1136 0.86

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	2e-05	0.0012	18.7	0.1	1	23	138	161	138	161	0.96
2	15	0.0011	0.064	13.2	2.9	2	23	210	232	206	232	0.89
3	15	0.0091	0.54	10.3	0.8	1	23	317	340	317	340	0.93
4	15	0.17	10	6.3	3.4	2	23	389	411	388	412	0.95
5	15	0.00073	0.044	13.8	0.2	1	23	471	494	471	494	0.94
6	15	1.5	89	3.3	0.1	2	14	513	525	512	537	0.85
7	15	0.00024	0.014	15.3	2.7	2	23	545	567	544	567	0.96
8	15	9.9e-05	0.006	16.5	0.1	1	23	635	658	635	658	0.95
9	15	0.0002	0.012	15.5	0.2	1	23	706	729	706	729	0.93
10	15	0.00048	0.029	14.3	2.3	2	23	779	801	778	801	0.97
11	15	0.0059	0.36	10.9	1.7	1	23	882	905	882	905	0.92
12	15	0.039	2.3	8.3	1.5	1	21	957	977	957	978	0.95
13	15	0.05	3	8.0	0.2	2	23	1032	1056	1031	1056	0.86
14	15	1.7	1e+02	3.2	0.7	1	20	1075	1096	1075	1099	0.63
15	15	8.5	5.1e+02	1.0	0.4	14	23	1126	1136	1124	1136	0.86

Sequence Information

Coding Sequence: ATGGAAGGTATGGATTTATGGACGCGTATGTTCTCTGCTGATGATGAGGAGGGCGGCGAAGGTGACGCAGGCGTCAGAGAGTTAGAGCAGAATGACAACAATACGATGGGTGAAGATGTTGATGAatacgatgacgatgacgatgacgaggAGGAGGAGTCCAAAGGACCAGAACCTGATGATGatgccatttttaattttgaattgtcACCAATTGTAAATAGTGTGCTAGCGCCAGCCATACCAAGTGCGCCAAGTGTACGGCCTATACAGCGTCAGTCGCTACAAGCAAGCTTTGGTTCAGCGCAGGAGCGCATAAACACAGGCACTACTTCCATTCGCCCGAAGACTTCACAAATCAATGCCACCGATGAAAATGGCGTGCTTATTAATTACGAGCTCGgcgttatatacatatgtccaGCATGTGGTACCGAGTTTCGGCAACAAGATATGTGGAAGCGTCACATGAACAATATTCACCAGTTCAATACGCGCCGTGGTCtgaattttgttgctattgacAAGTTGTACCAACGCTGCCTAGAGTGCAACAAGCGCATTGCAATGCATAGTCGGGAAAATCTGCTAAAGCACAAATTTACGCATCTGCCATATAGATGCACCAAGTGCTACATATGCAAGCGAGAGTACAAATATCGTCAGGACCTAATGGTACATCTGCGTATGGTGCATTATGAAGAGGTTGTGATTCTGATGCGAGAAGGTGACAATGGCGCTGCTGGTCGCAAAACACGTGTACGTGAGCCACGCACAGAGCTACGTTATCCGGATGATGACGAGGGCATAGAAGTGCGTAATGAGCTGCTAGAGCCGGATGCCATAGAGTCTGCCAATGATGAATTCCAACATAGCAGTTCCACAGCAACCCAGCGGCAACGCAGTGGTGCTGGTAATGCTGCTGACTTTTGCGAGGATTATATACACTACATGTGCCCGGATTGTGGAACAGATTGCGAAACTCACGCACAGTGGAGCCAGCACATTGAATTTGTTCATGATTATGTCAGCAGACGTGGACTAAACTTCCGTTCTGTAGACATGCAGATGCAGTGTCTCGAGTGCAAGCAGtttgtGTCGCCCAATACGATGAAGACACTGcgtgtgcataaatttagtCACTTGTCGCAGCCCGAATGGATGCGTTGCAAACTATGCTACAAAGGCTATACGGAACATCAGGAGCTGGTGAGCCATCTTCTGAAGCAACATCATTTGGAGACCTTGATGCCGCCCGAAAACGGCGCGCCTGTCGACGGTACAGCTGATGGCGATGATGCGATGCAAATTGACGCCGGCAACGATTGCACAGATGAATTGCAGATGGAAGATGCGCCCAAACGTGGTGCTCGTATTGCCTTCGATGATATGTATGAGCCGCATATAGACTATCTCTGCCCGCAATGCGGCAGAGAGTTTATAGAGAAGAAACAATGGCGCAATCATGTGGAAAAGGTGCATGGAATGAACGATTTGTCGCAGCTTAACTTTAAGGTGATAAACGATCGTCAGCTAAAGTGCACCGAATGCGATAAGATTATAACAAATGCCTATGGTATACAGAATGCACAACAGCATCGCATAACGCATTTGCCCTACAAATCGTATATACGCTGTCGCAAATGCCACAAATCCTACACGGATCGCAAAGGACTGGTCAAACATTTGGCCACTAATCATCGCATAGGCTATGATCCCCGCCGAGGGGTAATAGCAAAGTCGTTGCCACGTAAACAAATCGTCACTGTTGCCAATGAAACGTATGAGATTATTTATTTGGATGAGGATGACCAAGCGACTGAAGAGAATGACTTTGCTGAGCAAATGCAAGCAGATCCTGATGATGACTTTTTTTTGACTCTAAGTAGCATAAGCAATCGATACAAGTGCGTTGACTGCGGAACGCTTTTTGCAACGAGCGCAGCTCTCAAAACGCACATAAGCGAAGAGCATGACTTCTCGGATACACAATATAGTGCCAAAAATGCCGAGCCAGTAGAAGATGCTGAAGCTGCAATTCCTacgtcaacagcaacaacaacaattagcatGCTCCATTCAGCTGGCAACTCAACTATCGAAcagaattatatttttttgtgtccATCATGCGGGGAGACATACAAATCGCAGTTTGAGTGGCGTCGTCATATTAACGAAGCGCACAACTTTGATAAACGTCAGTATTTGAAAATGCGCCAGGTAGACAAGTATCGTTATCAGTGCACCTTGTGCAAGGATATCGTGTGTAATTCAAAGTTAAAGGGACTCCAGGATCATCATTTTAGACATTTGGCCTATCGCTTGTACCTCAAGTGCTTGATTTGTGGCACCTGCTATAACCACAAGCCAAACATAGCTGCACATTTGCGCACGCGTCACAATATTTTCGAACGCGAGTCCAAGTATCATGCAGCTCAAGAGAGGGAAGGAGATAGAGAGCGGGGGGATACAGATAGAGAGCGTGGCATGTCCTCAGCTTCATCTTCACCCACGCCAGGCACTAGCCAGGGACGTGCGCTAAAAACTCAACCAGGCTTGCTGCCCACACGACCTGTTGGCCTCAATACGCTTGAGGATAGCATCTCCTACCACAATGCTGTCGATTTAGATTTCATTACCTACTATTGCCCCAAGTGCAATCAGAACTTTGATTCACACGCCTTTTGGCGCAAGCACATTGTCGAGCAGCATAACTTTAACAGTCGTCAGGGCTTGAATTTTCGGCAGCTTGACAACCATCATTACTTATGCCTGGAGTGCTACAAGCGTGTAACGGTGACGCATACCAAGGGCGCCATTGGGCAGCTACAATCACACAAGTTCCGGCATTTGCCATATCGCTCCTTCAAGTGCTTAACATGCAATGGCGAATTTGTGCGCAAACAAATGTTCTTCAAGCATTTAAATCGCAATACCAATCGCTGTGACAATCGCCCGCAGAGTGATAACGAAGACGAGCAGTCCGGAGGAtcacagcagccagcagaaGCAGTCAGCGCTGAAGCTCACATAGATATAGACCCAAAGTTAAACTTTGATTCTACTACTGCACCTGTGCCATATCGCTTAATTTGTCCGCAATGTGGTGATAGCTTTAGTACCAGCAGCAAATCGCAGTGGCGCGAACATATTAACATTTACCATGGCATGGGCAAACGTGAGACACTGCATATGCGCAAAGTGGGTGGTGATGATCTCTATCGCTGCAGCGATTGTGATCAACAGCTGCAGACAAAGCAGCTTCGCGTGCTGCAACAGCAtagatttatgcatttgccCCATTCTGATTACATACGCTGTCTGCTTTGCGTGCAAGGCACTAGCGATACGTTGTCCGGCATGCATAATTTCCGTGAGCTGCAACAACATATGCGGCAAGTACATGTTCAGCACACCGATGATCAGCTGCCAATGCAGCTGGTTGAGGATGATAGTTTGCCCTACAATGAAACGGAGGAGTTGTTAGCGCCACAGACACATCTACTGGACGATGATATAGAGGACCAGTATTTGTTGGGCTAA
Protein Sequence: MEGMDLWTRMFSADDEEGGEGDAGVRELEQNDNNTMGEDVDEYDDDDDDEEEESKGPEPDDDAIFNFELSPIVNSVLAPAIPSAPSVRPIQRQSLQASFGSAQERINTGTTSIRPKTSQINATDENGVLINYELGVIYICPACGTEFRQQDMWKRHMNNIHQFNTRRGLNFVAIDKLYQRCLECNKRIAMHSRENLLKHKFTHLPYRCTKCYICKREYKYRQDLMVHLRMVHYEEVVILMREGDNGAAGRKTRVREPRTELRYPDDDEGIEVRNELLEPDAIESANDEFQHSSSTATQRQRSGAGNAADFCEDYIHYMCPDCGTDCETHAQWSQHIEFVHDYVSRRGLNFRSVDMQMQCLECKQFVSPNTMKTLRVHKFSHLSQPEWMRCKLCYKGYTEHQELVSHLLKQHHLETLMPPENGAPVDGTADGDDAMQIDAGNDCTDELQMEDAPKRGARIAFDDMYEPHIDYLCPQCGREFIEKKQWRNHVEKVHGMNDLSQLNFKVINDRQLKCTECDKIITNAYGIQNAQQHRITHLPYKSYIRCRKCHKSYTDRKGLVKHLATNHRIGYDPRRGVIAKSLPRKQIVTVANETYEIIYLDEDDQATEENDFAEQMQADPDDDFFLTLSSISNRYKCVDCGTLFATSAALKTHISEEHDFSDTQYSAKNAEPVEDAEAAIPTSTATTTISMLHSAGNSTIEQNYIFLCPSCGETYKSQFEWRRHINEAHNFDKRQYLKMRQVDKYRYQCTLCKDIVCNSKLKGLQDHHFRHLAYRLYLKCLICGTCYNHKPNIAAHLRTRHNIFERESKYHAAQEREGDRERGDTDRERGMSSASSSPTPGTSQGRALKTQPGLLPTRPVGLNTLEDSISYHNAVDLDFITYYCPKCNQNFDSHAFWRKHIVEQHNFNSRQGLNFRQLDNHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPYRSFKCLTCNGEFVRKQMFFKHLNRNTNRCDNRPQSDNEDEQSGGSQQPAEAVSAEAHIDIDPKLNFDSTTAPVPYRLICPQCGDSFSTSSKSQWREHINIYHGMGKRETLHMRKVGGDDLYRCSDCDQQLQTKQLRVLQQHRFMHLPHSDYIRCLLCVQGTSDTLSGMHNFRELQQHMRQVHVQHTDDQLPMQLVEDDSLPYNETEELLAPQTHLLDDDIEDQYLLG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -