Dbus001908.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila busckii
Gene Symbol
L
Assembly
GCA_011750605.1
Location
NC:12498000-12506023[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 6.1e-06 0.00037 20.3 2.9 1 23 164 186 164 186 0.98
2 15 0.21 13 6.0 6.2 1 23 192 214 192 214 0.97
3 15 1e-07 6.1e-06 25.9 3.2 1 23 220 242 220 242 0.99
4 15 7.5e-06 0.00045 20.0 0.4 1 23 248 270 248 270 0.99
5 15 0.011 0.65 10.1 0.2 2 23 339 363 338 363 0.91
6 15 0.0014 0.082 12.9 0.4 2 23 389 411 388 411 0.95
7 15 0.037 2.2 8.4 0.7 1 23 489 511 489 511 0.97
8 15 0.013 0.78 9.8 0.1 2 23 519 540 518 540 0.91
9 15 2.2 1.3e+02 2.8 0.2 1 16 548 564 548 566 0.84
10 15 0.003 0.18 11.8 1.2 2 23 613 635 612 635 0.96
11 15 0.069 4.1 7.5 0.1 1 23 641 663 641 663 0.92
12 15 0.29 18 5.6 0.4 2 23 671 692 670 692 0.94
13 15 0.24 14 5.8 1.2 1 23 786 808 786 808 0.94
14 15 0.019 1.1 9.3 0.0 1 23 818 840 818 840 0.96
15 15 0.00046 0.027 14.4 2.0 1 23 845 867 845 867 0.97

Sequence Information

Coding Sequence
ATGATGGCTTTAAAGATGCTCTATCGTGGTCCCAGTTCGCGTTTAgagaatttaattgaaaagatTCAGGCTACCAAGGAGATTACAGCTAACGaCATGTACAGCACGCACACCTCCTCCAGCTACTCGCCCAGCATCTCGGACGGCACACTGACGCCCAACTCGCAGCAGCCTCTGATGGCGGCGCCTGGCTGCGAGGAAAAGGAAAAAACAAATGGCGATGCCAATGCCACAGATctggagcaacagcagcaggagcaggagccaCGCAAACCGAAGCGTCCCAGCCActtgcatcatcatcatcatcattatcatcatcagcaggCGCTGAAGCTTGCCAACAAGCTGCGCAAAATCAATAAGGAAGCCAAGCTGGCAGCTCAGACTGGCGCGGGCGCTGCActcggcgctgctgctggcgccggaGTCACCGCAAAGTTTGATAAGTTGACAGGCGAGGGCATTAAGAGTCGCGGCGACGGCTCCTATCAGTGTCAGTTCTGTGATAAATCATTTCCGCGTCTCGGCTACTTGAAGCATCACGTGCAGAGCCATGCTGAGCATTTGCCTTTCAAATGCGAATACTGCGCCAAGCTGTTCAAGCACAAACGCTCGCGTGATCGCCATAAGAAGCTCCACACCAACGAGCGCAACTACAAGTGTCCACATTGCGAGGCTGCTTTCTCCAGAAGCGATCATCTGAAGATTCACATGAAGACGCACGACATACAGAAGCCGTTCCAGTGCAGCATGTGCAATCGTGGGTACAACACGGCGGCAGCGCTGACTTCGCACATGCAGAAGCACAAGAAGAACGCGGCCATTTTGGCAGCTGGCGGCAATCCCAATGCATTGAACTACAGTCCACGCAGCACTGGCTCCGCCTCCATCTCGAGCAATGGGAGTCTGCACAAGCGGCGCTATGCGCTGGCGCTCGCCAGCGACAGCAGCCCCAGTCGCCTGGAGTTTCCCAAGCGCGCACGCAgtcatgccacgcccacgccgctgctgcgctgcaatTACTGCGTCAAGGCGACAGAGTTCAGCAGCTTGGAGCAGTTGAATGCGCATATGCAAAGTGtgcacgagcagcagcagcagcagcagcaggcggggGCGACGCCCAAGAGCGGAGCAATGGAGAGCGAAGGCTTCCAGCTGAGCTGTGAGTACTGCACCATGAAGTTTGGCAACATTGCCACGCTCTTTCAGCATATGCGAGCGACGCACTTGGATCGTCTGAGCAGTCCCAATAGCTACTATGAGCATTTCAATAGACTGGCCACGGCGGGCACGTTTAGTCCCAGACTAGCGCTGGAGCTGCCAAAGCTTAAAGAGCAGCCAAACTCACCGCATAACAAGCCGGAGCAGGAGCTGCCTACAGATCTCAGCAGCAATAAGCGACGCAgcgcagcgacgccgccgccgccagcagcagcagctacaacaccCGCTGGCGTGTTCTTTTGCAATCAGTGCAACGCTGGTCTGCCGGACTTTGAAAGCTTTCGCAATCATTTGAAATCGCACATAGCCGAGGGCATGCAGCTGAGCTGCCCGCACTGCGGTCTCAATCTGCCCGAGCAGAGCGAATACGAGCGGCATGTGGTTGCGCATTTTCTCATCAGCGGCAGCGAGTTCAACTGCAGCGCCAGCTGTGGCAAAAGCTATGCCAAGGCAGCGGCATTTACTTACCTGAAAGCTATTAGCGGCAATGTGCAGCCAAGCGGCAGCTTGAGCTGCGGCATGTGCGAGCGTCAGGATCTGCGCAGCGAGGCGGAGCTGCAATCGCATCGCAAGCTGGCGCATAATCTCAAAACCGGCGTCAGTCTGCGCTGCGCTTACTGCGCGGGCAACTTCAAGTCACGCgctgagctggagcagcacATGAAGAGCTGCCACAACTCGAGCGGCAAGCACAAGTGTCTCATATGCGATGAAATCTTTCCCTCGCCCGCCATTCTGGCCgagcacaagctgcagcactCCAAGGTGGGTCAGTCCGGCAAGTGCGCGCactgtggccagcagctggagcatGTCGCCGCCTATCGCGCGCATCTCACCGCTCATGGCAGCGATGGCAATTTGCCGCTCGCCTGCATCTGCTGCCGCCAGACGCTGCACTCGGAGTTCGAGCTCAGTTTGCATGCCAAGTTCCACACCAAGACCAACAACGCCAGCGGCAGTCTGCAGGAGCCAGTCTGCGCTCTGTGTCTGGAGCCGCTGCCTGGAGCTGGCGACACCGCCAAGCTTTGCGAGCAATGCTGCCGCAAGCATAATCTGAATGGcaagcgcagcaagcagccCACGCCTACGCCAGCGGCGCATGCAGGCGGCAGCTACTTGGAGCATCGCTGCAATCTCTGCAAGCTCATCTTGCCGCATGCGCAGAAGCTGCAGGAGCATCTGGTGGAGCACACCTTTGCCGGCACCGAGCAGCGCGGCTTCAACTGTTACATTTGCTCTGCTGTCTTTACCGCTCCCGCGGGTTTGCTCACGCACATTGCCGAGCATGGCGCGCGTCCTTATGACTGCAATTTGTGCACGGAAAAGTTTTACTTTCGCGCCGAGCTCGAGCATCATCAGCGTGCCCATGAGCTCAGAGCTGCAATGCGCCCCAAGCAGGAGCCGCCACTGGACAGCGCCACACCCTCGCCTCATCCTTTGAGTCCCACGGTGCCACAAGTCAAGCAGGAGCTCTTTGACAGCGAGCCTGCTGCATCgccagctgccgctgcagctgctgctgctgctccagacGAGGAGGAGTACATTGAGGTGGAGCAAGTGCCGCAGGAGACGCGCGCCAACGATTTGCTCAACAATGCGCATGCCGaacgcgccagcagcagcgcctaa
Protein Sequence
MMALKMLYRGPSSRLENLIEKIQATKEITANDMYSTHTSSSYSPSISDGTLTPNSQQPLMAAPGCEEKEKTNGDANATDLEQQQQEQEPRKPKRPSHLHHHHHHYHHQQALKLANKLRKINKEAKLAAQTGAGAALGAAAGAGVTAKFDKLTGEGIKSRGDGSYQCQFCDKSFPRLGYLKHHVQSHAEHLPFKCEYCAKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASISSNGSLHKRRYALALASDSSPSRLEFPKRARSHATPTPLLRCNYCVKATEFSSLEQLNAHMQSVHEQQQQQQQAGATPKSGAMESEGFQLSCEYCTMKFGNIATLFQHMRATHLDRLSSPNSYYEHFNRLATAGTFSPRLALELPKLKEQPNSPHNKPEQELPTDLSSNKRRSAATPPPPAAAATTPAGVFFCNQCNAGLPDFESFRNHLKSHIAEGMQLSCPHCGLNLPEQSEYERHVVAHFLISGSEFNCSASCGKSYAKAAAFTYLKAISGNVQPSGSLSCGMCERQDLRSEAELQSHRKLAHNLKTGVSLRCAYCAGNFKSRAELEQHMKSCHNSSGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCAHCGQQLEHVAAYRAHLTAHGSDGNLPLACICCRQTLHSEFELSLHAKFHTKTNNASGSLQEPVCALCLEPLPGAGDTAKLCEQCCRKHNLNGKRSKQPTPTPAAHAGGSYLEHRCNLCKLILPHAQKLQEHLVEHTFAGTEQRGFNCYICSAVFTAPAGLLTHIAEHGARPYDCNLCTEKFYFRAELEHHQRAHELRAAMRPKQEPPLDSATPSPHPLSPTVPQVKQELFDSEPAASPAAAAAAAAAPDEEEYIEVEQVPQETRANDLLNNAHAERASSSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
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90% Identity
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80% Identity
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