Basic Information

Insect: Drosophila busckii
Gene Symbol: RREB1
Assembly: GCA_011750605.1
Location: NC:17875156-17884406[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.034 2 8.5 0.9 1 21 245 265 245 267 0.93

2 12 0.00024 0.014 15.3 0.2 1 23 277 299 277 299 0.98

3 12 5.8e-05 0.0035 17.2 7.3 1 23 305 327 305 327 0.98

4 12 1.3 78 3.5 2.8 2 19 535 552 535 555 0.93

5 12 0.029 1.8 8.7 0.0 1 23 671 693 671 693 0.97

6 12 8.9e-06 0.00053 19.8 0.7 1 23 703 725 703 725 0.99

7 12 0.0006 0.036 14.0 2.0 1 23 731 754 731 754 0.97

8 12 0.0021 0.13 12.3 2.0 1 23 989 1012 989 1012 0.95

9 12 6.2e-05 0.0037 17.1 0.3 2 23 1357 1378 1356 1378 0.97

10 12 0.1 6.2 7.0 6.3 1 23 1384 1407 1384 1407 0.97

11 12 0.061 3.6 7.7 1.1 3 23 1609 1629 1608 1629 0.91

12 12 0.001 0.06 13.3 4.8 1 23 1635 1657 1635 1657 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.034	2	8.5	0.9	1	21	245	265	245	267	0.93
2	12	0.00024	0.014	15.3	0.2	1	23	277	299	277	299	0.98
3	12	5.8e-05	0.0035	17.2	7.3	1	23	305	327	305	327	0.98
4	12	1.3	78	3.5	2.8	2	19	535	552	535	555	0.93
5	12	0.029	1.8	8.7	0.0	1	23	671	693	671	693	0.97
6	12	8.9e-06	0.00053	19.8	0.7	1	23	703	725	703	725	0.99
7	12	0.0006	0.036	14.0	2.0	1	23	731	754	731	754	0.97
8	12	0.0021	0.13	12.3	2.0	1	23	989	1012	989	1012	0.95
9	12	6.2e-05	0.0037	17.1	0.3	2	23	1357	1378	1356	1378	0.97
10	12	0.1	6.2	7.0	6.3	1	23	1384	1407	1384	1407	0.97
11	12	0.061	3.6	7.7	1.1	3	23	1609	1629	1608	1629	0.91
12	12	0.001	0.06	13.3	4.8	1	23	1635	1657	1635	1657	0.99

Sequence Information

Coding Sequence: atgcttgccgcacagcagcagcaacaacaacaacaacagcaacacacagcagcaacagcagcagtaacaacaacaacacatggCCTTGGCAGCGATATGGAGCGCCAACGTCGCGAGTCAACCACATCCGAATCCTCGCTGGAGCATTTGGATTTGGGACGCACACCAAagaagctgagcagcagcagcggcgcagcGCAGCCAACGTCAACGCCACatgaggcaacaacaacaacaaaccgcAAACGCAAactgcgacagcagcagcagcaattgctctCAGAtgaggaagaagaagagcaacagcagcagcagcagcaactcgagTCAACAACGCTGCGCATACGTCACAAGCAGCGACGCAGTCAaagcgctgctggcgccgctgccgtcgctgctgctagCGCCAGCATTGTTGACGACGGCGACGCCAGTTCGCTGCGTAAAAAGTTCCGCTTGAATCGCAGCAGCCAGGCGGCCAACAGCGATCTCTCCGAGTCGGGCTTCATCGATGGCAGCGCTTTGAGCAGCTATTTGcttagcaacagcagcagcgttaacaacagcagcagcagcgctgccgctgcgcagTCATCTGCTGTTGCAGCCGGCGCCGCctcgaccagcagcagcggcagctctgGCGGCAACTCGGGCGGCTCCTCGCCCCAGGGCGGCCTCTGCCTCTCGAGCGCCGAGTCCGGCATCGGCGCCAGCGATGAGCACATGAAGTTCCTCTGCCCCATCTGTGAGGTCGTCTCGGCCACGCCCCATGAGTTCACCAATCACATACGCTGCCACAATTACGCCAACGGCGACACCGAGAACTTCACCTGCCGCATTTGCTCCAAGGTGCTATCGTCCGCCTCCTCGTTGGATCGCCATGTGCTCGTCCACACCGGCGAGCGTCCGTTCAATTGTCGCTACTGTCATCTGACATTCACCACCAATGGCAACATGCATCGTCATATgcgcacacacaagcagcatcagcagccaacagcaacagcagcagccacaccacagcagcaacagcgacgccaccagcagcagctgcagcagcagcaacaacagcagcagcagtcagaggGCGTGGCCAGAGAGAGCTACGAAAGTGATGCTAGTTGCAGCACAGATGTGTCCAGTGCGCAaagtcacagcagcaacaataacaataacaacaacaacaacaaaatgaacaacaataatttaaataataataacaatggcGAGCTGAGCAAGCGCACGCGCttgaaattgaataataataataatatagttaatgagcagcagcagcaagagcaggcgctgctgctaacCAAACAGGAGCTGGAGGATTACGACGaggacgagcagcagcaagatgaagttgatgatgatgccgTTGATGTTATAACCAGCACACCCGATGTGGCTACGCTGCTGGCACACAGCTCGGAGCACAACTCATGCCAGAGCAATGCAAGTGACAGTCCCAGTCGCAGTCTGAGTccaccgctgccgctgccgctgctgggcTGTCCGGCGTGCGCTGCCTGCGATTTTGATAGTTTGCCAGCGCTGTTTGCGCACTTGGATGCCGCGCATGCGGATATACCCGCCAAGTGTCGCGAGTGCGATGTGATCTTTCAAAGTCATCgccagttgcagctgcacaaTTGTCGCgcagcgggagcagcagcagcagccatgtcgccgccactgccgccgctgctgggcGCCAGCAGTTCGCCCATACATAAGCAGGAAGCGCCCGAGCTGGAGGAGGATGAAGATGAGGATGCGGATGCGAATGAAGCGCCCGCTGCCGCTGGCGGAAATGCCACCGACCTGGCGGACATACAAAGCATTCTGAACATgaccagctccagctgcacgTCGAGTCTGCTGCGCAGCTTCGAGCAGAGCGTGCACACGCCCTGCAGCAGTCAGTACAGTTTGGATGGCGGCGAGGAGGAGGCGCAGGATGCGTTCACCAGCGAATTTCGACGCATGAAGCTGCGCGGCGAGTTCCCCTGCAAACTCTGCGCCGCCGTCTTTCCCAATCTGCGTGCGCTCAAGGGCCACAATCGCGTGCATTTGGCAGCCGTGGGCGCCGCTGGACCCTTTCGCTGCAACATGTGCCCCTACGCCGTGTGCGACAAGGCGGCGCTGGTGCGGCACATGCGCACCCACAATGGCGATCGCCCCTACGAATGCGCCGTTTGCAATTACGCGTTCACCACCAAGGCGAACTGTGAGCGCCACTTGCGCAATCGACATGGCAAAACGTCACGCGAGGATGTCAAGCGTGCCATTGTCTATCATCCGGCGGAGGATGCCAGCTgcgatgagcagcagcagcagcagcagcacaacaaatcGAGCGCATCTGAGTTGGATTTGAGTTATCGCGAGctaacgccaacgccagcagcgctgccgcagTCAGACTCGCAGCTTAAGCACATGCTGCTGGCagagccaacagcaacagttgccgctgTGCCTGCGCCTGCGCCAGCAGCCAAAATACAGGTGAAGAGCTTGGATCAGCTGGTGgaaaaaccagcagcagcagcagcagctttggatTTATGCAACGATGTGTTGGATCTAAGCAAaaagccagcagcgctgccagctgcgctcatacagcagcagcagcagcagcaacatgctttggagcagcagctgctgttggcgcaacagcagcagcagcagctctttgCTGGCGATGCTGCCACGCAGTACATGCAACTGTTTCGCAATTTAATGTTTCAACAAAGCAATGGATTTCCTTTCTTCAATCTAATGGCGCCGCTTGCAACAGacaaaactgcagcagcagcagcagcagcagcaacaacagcaactgctgctgttacgctgccgctgcctgcggGCGGACCCGTTAAGATGGTCATCAAGAACGGCGTGCTCATGcccaagcaaaagcagcgtCGCTATCGCACCGAGCGTCCCTTTGCCTGCGAGCATTGCTCGGCGCGCTTTACGCTGCGCAGCAACATGGAGCGTCAcgtcaagcagcagcatccgcAGTTCTATGCGCAGCGCCAACGCAGCGGTCATCATGTTATGCGTGGACGCGCAGCCAGCgccaatgcagctgcagcagcagcggcagcagcagcagccgccgcagcagccatgagcaatctgcagcagcagcagcagcagcaacatcagcagctgcagcaacaacatgcgcCCATCTCCGAGCATGTGAAATATGCAATTTTGgcgcagcagcttaaagcgcGCACAGACACCGATTTGTTGCAACAGGCGCTGGcgcatggcagcagcagcattgcagCCAATCCGCTGCTGCATTTTggctacaacagcagcagcggcagcaacacaaGCGCTGCCaagcctgcagcagcagcaatggacGATGATGAGCCCAAGCTTGTTATAGACGAAGATGATGAGGCTGATGACTTggatgatgacgacgatgaggATGAGCTTATGGAGGAAGACGACGATGAAGAGCAGTACgatgaagatgatgatgaggaggagcagcagcagcagcagcagcagccagttgCTGGCGAGTTgcagccaccagcagcagtgccGCAGCCACCGCCAGCAaacactgccacgcccatagcagcagctaaaaaagtAGCCGAAACTATTTTGGAGCAAGCCATCAAAGCGGGCAAACCAGTCAACGAAGCAGACCCAGCCCCAGGGGCAACTCCAGCcgatagcagcagcttgaagaGCCTCATCAGCCAGGCCGAGTCCGTTGCCAAGTCGCTCAAAGATGTGGCCAGCTCAGCGTTCAAGGATGAGTCGCAGGATCTAGTGCCCGTTGCCAAGCTGGTCGACAATGCCACCAGCAATCAGGTCAGCTTCAATAGCTACTTTCGCCCCAGCGATGTGGCCAATCATATGGAGCAAAGCGATGAGGAGGGCTTGGTggccagcggcagcgccagcgagagcaacaacagcggcacCGAGGAcgtcaccagcagcagcagcagcagcaatggcgcCGATACCAAAAAGAAATCCGCCTACAGTCTGGCGCCCAATCGCGTCAGCTGTCCCTACTGCCAGCGCATGTTCCCCTGGAGCAGCAGCCTGCGCCGTCACATTTTAACCCACACTGGCCAGAAGCCGTTCAAGTGCAGCCACTGCCCGCTGCTGTTCACCACCAAGAGCAACTGCGATCGCCACTTGCTGCGCAAGCACGGCAACGTTGAGTCCGCCATGTCCGTCTATGTGCCCACCGAGGATGTCAGCGAGCCAATACCGGTGCCCAAGTCGGTGGAGGAGATCGAGCTGGAGGAGCAGCGACGTCGCAAGCAGGCTGCGGCCGccgagctggagcagcagcggcagcgcgaacgcgccgagcagcagcagcgtgagcGCGATCtggagcgtgagcgtgagcgcgaGCGGGAGCGTGaacgcgagcagcagcagttgatacagcagctggcggcggcagcgcagcTCAGTCAGCagatggcggcggcggcggcagcgcaagcagcagcagcagcagctcttaatggcaacggcagcagcaacagcaacaattgcagcgaTTCACAGTCAAGCGATTTGCCCTACAAGTGCCATCTCTGCGAATTTAGCTTTGCCGAGCGTCTGCAGTGCTTGGAGCACATCAaacagtgccacgcccacgagtttgcgctgctgctggccaaaggCGCCATCGAAACCgatgcacagcaacaacaattgccgcCGCCATCGAACTCGGACGATGAGTCCTCAATGCTGCCACGTGGCAAATACCCGGACTACAGCAATCGCAAAGTGATCTGCGCCTTCTGCATGCGCCGCTTCTGGTCCACCGAGGATCTGCGTCGTCATATGCGCACCCACTCGGGCGAGCGTCCCTTTCAGTGCGACATCTGCTTGCGCAAGTTTACGCTGAAGCACAGCATGCTCCGGCATATGAAGAAGCACAGCGGACGCAGTCACAATGGCGATGCATTGGGCGCATCCGATTGCTCCGATGATGAGCAGCCggcaacgccgccgccgtcctcacagcagcagcagcagcacaacaataacaatacttgccacaacaacaacaataacaacaataataataataataacaacaacaacaacaaatcagcGCAACTGCGTCTGCCAAAGCTGCATGAGCAGCTGGACAAGGAGAATCTGGGCGAGGCCAGCACGACGCCGTCGGCTGCGGCCAGCGGTGATCTGATTGGCAATCTGTTGGGCATTAGCGATCAGGGCATACTCAACAAGCTGCTCTCCTCGCCCGATGAGGCGGCCAAGCTGTTGGGCGTCGAGTAA
Protein Sequence: MLAAQQQQQQQQQQHTAATAAVTTTTHGLGSDMERQRRESTTSESSLEHLDLGRTPKKLSSSSGAAQPTSTPHEATTTTNRKRKLRQQQQQLLSDEEEEEQQQQQQQLESTTLRIRHKQRRSQSAAGAAAVAAASASIVDDGDASSLRKKFRLNRSSQAANSDLSESGFIDGSALSSYLLSNSSSVNNSSSSAAAAQSSAVAAGAASTSSSGSSGGNSGGSSPQGGLCLSSAESGIGASDEHMKFLCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLTFTTNGNMHRHMRTHKQHQQPTATAAATPQQQQRRHQQQLQQQQQQQQQSEGVARESYESDASCSTDVSSAQSHSSNNNNNNNNNKMNNNNLNNNNNGELSKRTRLKLNNNNNIVNEQQQQEQALLLTKQELEDYDEDEQQQDEVDDDAVDVITSTPDVATLLAHSSEHNSCQSNASDSPSRSLSPPLPLPLLGCPACAACDFDSLPALFAHLDAAHADIPAKCRECDVIFQSHRQLQLHNCRAAGAAAAAMSPPLPPLLGASSSPIHKQEAPELEEDEDEDADANEAPAAAGGNATDLADIQSILNMTSSSCTSSLLRSFEQSVHTPCSSQYSLDGGEEEAQDAFTSEFRRMKLRGEFPCKLCAAVFPNLRALKGHNRVHLAAVGAAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSREDVKRAIVYHPAEDASCDEQQQQQQHNKSSASELDLSYRELTPTPAALPQSDSQLKHMLLAEPTATVAAVPAPAPAAKIQVKSLDQLVEKPAAAAAALDLCNDVLDLSKKPAALPAALIQQQQQQQHALEQQLLLAQQQQQQLFAGDAATQYMQLFRNLMFQQSNGFPFFNLMAPLATDKTAAAAAAAATTATAAVTLPLPAGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYAQRQRSGHHVMRGRAASANAAAAAAAAAAAAAAAMSNLQQQQQQQHQQLQQQHAPISEHVKYAILAQQLKARTDTDLLQQALAHGSSSIAANPLLHFGYNSSSGSNTSAAKPAAAAMDDDEPKLVIDEDDEADDLDDDDDEDELMEEDDDEEQYDEDDDEEEQQQQQQQPVAGELQPPAAVPQPPPANTATPIAAAKKVAETILEQAIKAGKPVNEADPAPGATPADSSSLKSLISQAESVAKSLKDVASSAFKDESQDLVPVAKLVDNATSNQVSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSSSNGADTKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRKQAAAAELEQQRQRERAEQQQRERDLEREREREREREREQQQLIQQLAAAAQLSQQMAAAAAAQAAAAAALNGNGSSNSNNCSDSQSSDLPYKCHLCEFSFAERLQCLEHIKQCHAHEFALLLAKGAIETDAQQQQLPPPSNSDDESSMLPRGKYPDYSNRKVICAFCMRRFWSTEDLRRHMRTHSGERPFQCDICLRKFTLKHSMLRHMKKHSGRSHNGDALGASDCSDDEQPATPPPSSQQQQQHNNNNTCHNNNNNNNNNNNNNNNNKSAQLRLPKLHEQLDKENLGEASTTPSAAASGDLIGNLLGISDQGILNKLLSSPDEAAKLLGVE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -