Dbus011417.1
Basic Information
- Insect
- Drosophila busckii
- Gene Symbol
- -
- Assembly
- GCA_011750605.1
- Location
- NC:6042813-6045775[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 14 0.0064 0.38 10.8 0.3 2 23 22 43 21 43 0.96 2 14 0.043 2.6 8.2 9.1 1 23 49 72 49 72 0.98 3 14 1.7 1e+02 3.1 0.0 1 23 75 101 75 101 0.81 4 14 0.00097 0.058 13.4 1.1 1 23 117 139 117 139 0.94 5 14 5.4 3.2e+02 1.6 3.9 2 22 146 166 145 166 0.90 6 14 0.29 17 5.6 2.0 2 23 448 470 447 470 0.94 7 14 0.013 0.76 9.9 0.9 1 23 495 517 495 517 0.98 8 14 0.0062 0.37 10.8 2.3 1 23 525 549 525 549 0.94 9 14 0.2 12 6.1 2.2 2 23 554 576 553 576 0.94 10 14 0.00026 0.016 15.2 0.2 2 21 589 608 588 609 0.93 11 14 0.0045 0.27 11.3 0.3 1 23 617 639 617 639 0.98 12 14 7.9e-07 4.8e-05 23.1 2.8 1 23 645 668 645 668 0.98 13 14 3.2e-05 0.0019 18.0 1.4 1 23 674 696 674 696 0.98 14 14 0.00029 0.018 15.0 2.9 1 23 702 724 702 724 0.95
Sequence Information
- Coding Sequence
- ATGGcttCCCAAACAGGACAGAAACAGCTTGTTGAGATCACAACAGATGGTGTGCCCAAGCTACACTGTCCCGTCTGCAACAAGGCATTAGTCTCGCTGGCTGGCTATGTGAAACATGTGAAGAAACACGAACCGCCGGGTGGCTTTCAATGCCGTTACTGTGATGCCCACTACTGCCATGAGCATTTGCTGAAGGATCATATAAAGAGCACACATGCGGCTTTTACCTGTCAGCTATGCGTAGGAGACCAAGTGATGTTCAATACGAAGGCTGAACTCGACGCCCATATTGAGGAACAGCATCAAGACCGCAAGTTTAATGTGGGACTGGCTAACAGTGAGTTGCCCTTTAAATGCGAGATCTGTGGCAAGGGCTTTGCAGATCGCGAAAGCAGCCAAACGCATCATTCCGAGCACTTGAAAGCATTACCTGTGGAGTGCAAATGTTGTGCTATGCGCTTCACCTGCCAATCCAGCTTGATTAAGCATCAGCGCAAGCGTCCAGATAGCTGCGGACGTCTGGAAGAGGAgtccaaaaagaaaaaaagtttGCCTGTTCCTATAGAGCCTGCCACAGGCAAAAAGAAACGTGGACGCCCCAAAAAGTGTGTGGCGCATGCTGCAGATGACAGCGATGATGATATGCCACTGGCCACTAGACTAAAGACACCAGCGCCACGCCTTAAGCAGGAAATCGTTAGTAGCCAGGAGCTCAGCGATTCTGCCGAAGAGTATCCCGACTTTGAGCCCAACAACAGCGAAGATGAGACGGATGCAGGACAGTTCAAGCTGCCAACGCcagccaaagtcaaagaggAGACTCTAGATCCAGACTTTGAGTATCAGGATGCCAGTTTATTTGTCAAAGCGGAAGCAGCTGGTCTGGATATCTACAGCAATGAAAAAGACAAGCTGCTGGACGTACTGCTCAATTCGGATGAGAGCCTAAAACCGTATGAGAACTTAAAAGTGGAGCACGCCACGAGTGGCATACTGGATGAAATAGCAGCAGTGCCCATGGGCAAGCCGACTGGCGGTGAGCAGCAGGAGGAGGATGTGTTGGCGTTTCGGGAAACAGAGCATAATGGCTTAGATGAagacgacgatgatgacgatgatgatgatgatgacgatgacgacgacgacgacgatgacgactATGAGGAGGAGCAAGAAGATTTGAAGaaaaaatccaaaataaaCACTGTAAAGCGCAAGTATCGTAAACGTGGCACTGCAGGCACAAGTAATCATGAGAGTGGACCAAAGCGTGTTGCTAAAATCACCAAGAAGGAGCTAACGGAGCGATTGAAGATGATTAACAAAATGGAAAAGTCCTGGAAATGTCCACACTGCGTTAAAATCTATCACATACGCAAGCCCTATGAGAAGCATCTGCGAGATGATCACAAGCTCAGCGAGCTGGACATCAAGGAGCTATTCAAGGATGCGGATGCACATGCGAAGCTGGACGATGAAGTGTTTAAGTGCAAAATTTGCTCCAAAATTTATTTGGTGGAGAAACGTCTGGAAACGCACATGAAGGTGCATGGCAAGGATGGCAATCTGATATTCAAATGTCCTTGCTACTGCAATCAGTTCTTCGCCAGCAAGGAGCAAGCCACACAGCATGCCCAACAGGAACACAAGGAGCTGTTGTATTGCGAAAAGTGCGACAAGTACATGACCGGTCACGACAGTCTCAAAAATCACGAAAAGAACTATCACTCCAAGAAGGAACCTAGGAATCTGCCCAGGAATCTGATTTGCGACAAGTGCGGCAAAAAGTTTACCGGACGCACTTCACTCTCGGATCATGTGCGCTCTGAGTGCGGACGCATGCCTTTGTACGAGTGCACTGTCTGCTTCAAGCGTCTGTCCACTGCGGGCATATTAAAGACGCACATGCTGCTGCATCAATCTGAGACGCCCTATCAGTGCGACAAATGTGGCAAAACCTTCAAGGTGAAGGCGCAATACAAGTCGCATCTAAAGACACGCCACACTGACTATAAACCCTACAAGTGTCATCTCTGTCCCAAGGAGTACCCCTATCGCGAAAGTCTGCTCACTCACATGACTGTGCACACAGGCATCAAGCGTTTCCTGTGCAATAATTGCGGCAAGCGCTTCACTTGCATCTCCAATCTTCAGGCGCATCGGAAGGTGCATGCTGACACTTGTGGCCAGCTCCCATTGAATGCCAAGGCTACACAGTATATGGGCGTTCAGCGTGGCAAGCTCTTGATGGGCGCCAAGCCAGAGGCCGGCATGGAATATGAGGAAACCAAGACACTAATTGCACAGGATGTAATTGATCGGGATATGCCAATGGCACAGGAGCTCAACTTTCCCTCAGATGGCATTGCTCCGATGGCCACCGTGCCGCTTAACTACACCGCATCGCAGCTAGTGCCGCACATTATGCTACAGACCATGCAAGCTCAGGTGCAGGCGCAGGCACGTCAGCAACATTAG
- Protein Sequence
- MASQTGQKQLVEITTDGVPKLHCPVCNKALVSLAGYVKHVKKHEPPGGFQCRYCDAHYCHEHLLKDHIKSTHAAFTCQLCVGDQVMFNTKAELDAHIEEQHQDRKFNVGLANSELPFKCEICGKGFADRESSQTHHSEHLKALPVECKCCAMRFTCQSSLIKHQRKRPDSCGRLEEESKKKKSLPVPIEPATGKKKRGRPKKCVAHAADDSDDDMPLATRLKTPAPRLKQEIVSSQELSDSAEEYPDFEPNNSEDETDAGQFKLPTPAKVKEETLDPDFEYQDASLFVKAEAAGLDIYSNEKDKLLDVLLNSDESLKPYENLKVEHATSGILDEIAAVPMGKPTGGEQQEEDVLAFRETEHNGLDEDDDDDDDDDDDDDDDDDDDDYEEEQEDLKKKSKINTVKRKYRKRGTAGTSNHESGPKRVAKITKKELTERLKMINKMEKSWKCPHCVKIYHIRKPYEKHLRDDHKLSELDIKELFKDADAHAKLDDEVFKCKICSKIYLVEKRLETHMKVHGKDGNLIFKCPCYCNQFFASKEQATQHAQQEHKELLYCEKCDKYMTGHDSLKNHEKNYHSKKEPRNLPRNLICDKCGKKFTGRTSLSDHVRSECGRMPLYECTVCFKRLSTAGILKTHMLLHQSETPYQCDKCGKTFKVKAQYKSHLKTRHTDYKPYKCHLCPKEYPYRESLLTHMTVHTGIKRFLCNNCGKRFTCISNLQAHRKVHADTCGQLPLNAKATQYMGVQRGKLLMGAKPEAGMEYEETKTLIAQDVIDRDMPMAQELNFPSDGIAPMATVPLNYTASQLVPHIMLQTMQAQVQAQARQQH
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -