Dbus003895.1
Basic Information
- Insect
- Drosophila busckii
- Gene Symbol
- -
- Assembly
- GCA_011750605.1
- Location
- NC:14270651-14278730[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 5.9e-06 0.00035 20.3 1.1 1 23 314 336 314 336 0.98 2 12 0.00015 0.009 15.9 1.1 1 23 342 365 342 365 0.97 3 12 0.0026 0.16 12.0 4.0 1 23 371 394 371 394 0.96 4 12 9.8e-05 0.0059 16.5 2.5 1 23 430 452 430 452 0.96 5 12 0.032 1.9 8.6 1.0 1 23 458 481 458 481 0.90 6 12 0.0017 0.1 12.6 1.4 1 23 487 509 487 509 0.98 7 12 0.0028 0.17 11.9 2.2 1 21 515 535 515 539 0.90 8 12 0.00015 0.0093 15.9 3.7 1 23 777 799 777 799 0.97 9 12 8.8e-06 0.00053 19.8 2.5 1 23 805 827 805 827 0.99 10 12 0.00017 0.01 15.7 3.5 1 23 833 855 833 855 0.98 11 12 2.4e-06 0.00014 21.6 0.2 1 23 861 883 861 883 0.97 12 12 0.00078 0.047 13.7 4.9 1 23 889 911 889 911 0.98
Sequence Information
- Coding Sequence
- atggGTTTGTGCTCGAAGCGAACTTTAAAGCGTGGATCAGTGCCATGCATTAACAAAAACGATTGCAGTGAGGCTGAACGCGAACGTAGTGAAAAATGCAAGTATCGCCAACTGGTAGATGAACTGCTTGAAGAATCAGCTGCACGGGAAGCTGCTGAGGCTACTGGAGCATTTGTCACTGCGCCGGACTTTGTGCGCAATACAGGCATCGCCTCAGCTCCAGACTTTGTTTGTACCACTGGCAATGCTTTTATACCGGCTTCCTCAAGCGAAAACGATCCCTTGGGCGAAGCAGAACAAGACGCAAGTGCGCTCAATACGAGTATAGTTAACAAGGAGCAGCCTAAATGTCGCACTTGCAATAAAACTCTTGCTGGAAGCGAAACGTTCAAGGATCTTGGCAGTGAGGAAAATGCAGTAATGTTGCATCACATAGAAGTTATAACTGGCATTTGGATAAAATGTAATGGCAACTCGTCGCTTATGTGTACGAGTTGTGTAACGGATCTGCGTACTGCCATTGAATTTCGAGAAACCTGCATACAAACGGAGCTTCGACTGGCACACGATGAGCAGATCAAACGCGAAGCTAATGCAGCGCCTGTAGCTATGAAAAGCAATGATAGCAATGATGCGGAGTCAACAGGAAGgaaaacttttataattgaGCCAGTGGTGTATAAAAGAATTGATGAACAACCCATTGATGCACAGAGTGTTGCGCTGGGTACACAGATTTATGAGGAtctcttaaataaatataagggAGAGGATACAATAGGCATGCGACCAAAGAGACCAAATACCAGTAAATTGAAAGTAAAGCAACGAAAGTCACAGGTAAAAGCGCCCAAAACAGAAAAGCCAAAGACCAAGGACGAGATACGCTTACACCGCAATCGCGTGCGTCGTGAACAGATCAGAGCAGCGCCACTAAATTATGTATGTGATCAATGTGGTGCATCGTTTCGTGTTCGATGTAATCTAACAATACACATGCTTcgccacacacgcacaaagaaTTATCACTGTAGTGAGTGCCCCAAAGTTTTTTACGACGCCTACATGAGAAACATGCACATACGCGTGCAACACAAAGGCGAGCGGCCGTTTACATGTAATTATTGCGAAAAAAGATTCACTTCTTCCAATTCACGTTATTTACATGAAAGAAGATTTCATGGAGCCATGCCTCGTATTCAGCGCCATACGAGAGGCACTGAAGCTGCTAATGGGCTTGATAAATCTCTAACGGAAGTGAAGCATGAGCAAATGGAAAGTGTGCGCCACTATTGTACATATTGCACTAAAAGTTATGCCACCAAGTATGCGCTCAATTGGCATAACAATATACATTTGGGCGTGAAGCCTTTTAAGTGTAAATACTGTGAAATGGGCTTCTACGATCCACAGTCCAAATTGAAGCATGAGGTTATGCGTCATAATAGCAAGCGACCCTATGAATGCGATATTTGTCTTAAAACTTTCTTTGTGCGCACCAAATTCAGAGATCATGAGCGCATACACACTGGGGAGCGTCCATTTAGTTGTGAGGTGTGCAATGCGAATTTTCGTTACAGATACAATCTGTACACACATCGTTATAGTAAATTGCATAAAGCAAATGTGCAGCGCTTACTTAGTGTTGAGGAGCCAAaaatggaaatttgtataaagtgGACATTGTGTCGCACCTGCACTTGTGAGACTAGCGATACCGCCCAATTGCAGTCACTCTTTAGCGACAAATCTCTGGCCAAACAGTTGCTGGATTATTCTGGAGTTGCAGTGGATCCAAATGATGGCTTGCCAGATCAGATATGTAAGGATTGTATACACAGTCTTAATGCAGCACATTTGTTTCTTGTTGGCTGCAAACGAGCGGATGAACAGCTACGTAATGTTGTAGAGCGCACCAAAAGTGCCACCAAGGACTTtgatagcaaaagcaaaaggagcAGAAAAGCAGAGTCTACAACATCTGATGATGAAGACACTACGCTGCCAACGAAAATTAATATAGAGAGCAAGGAGATGAACGTTGACGAGCCGGAACAATTAGATATGTCAAAGGAAGAGAAAAAAAGCATACAAAGTGCAGCAGATTCCGCTGCACAGAACAATGAAGAATACTTGCTAGTTGTAAGCAACAAAGAAGAAGATAGCGATTGCAACGAATATATTATGGTTGACGTTGGTGATAATGATAATGTAATCGAAGAGTCTGATGCAGATGATGATTTTAATAAGAAAAACCCATCAGTTAAGGAAACGATTGAACGTACAGTTGACTTGGGCCCTGCTTGCGAGTCAGCCAACTTTTCCTATCACAGTTGCACCATTTGTTACAACTCATTTCCCAACAAAACGCAGCTCAAGAATCACGTACGCAAGCATTGCATTGTAAAGAACTATGAATGCGAACTATGCTCAAAGCGCTTTAATGCCGCCTGTAATCTAACAACCCATATGCGCACCCACACAGGGGAAAAACCCTTTGTATGCAACTATTGTGGTCGTCGTTTCGCGGATCGAAGTACCCATCGCAAGCATGAGCGtaTGCATACAAATGAACGTCCCTATGCCTGTGATATTTGTGGCAAGACCTTTTCGCTCTCAACGACGCTCAAGGCACATGCTCTAACACACACTAAAGAAAAACCTCACAAATGTTTAACCTGTAAAAAAGGATTTCGCCTGCCGCATCAGCTTAAAGCTCACGAGAAGACTCATACACATCGCTACGAGGTGAGCATAACGTATGATGATTATAATCAGGACGAAGACGACTCTGCCAGTAGTTAA
- Protein Sequence
- MGLCSKRTLKRGSVPCINKNDCSEAERERSEKCKYRQLVDELLEESAAREAAEATGAFVTAPDFVRNTGIASAPDFVCTTGNAFIPASSSENDPLGEAEQDASALNTSIVNKEQPKCRTCNKTLAGSETFKDLGSEENAVMLHHIEVITGIWIKCNGNSSLMCTSCVTDLRTAIEFRETCIQTELRLAHDEQIKREANAAPVAMKSNDSNDAESTGRKTFIIEPVVYKRIDEQPIDAQSVALGTQIYEDLLNKYKGEDTIGMRPKRPNTSKLKVKQRKSQVKAPKTEKPKTKDEIRLHRNRVRREQIRAAPLNYVCDQCGASFRVRCNLTIHMLRHTRTKNYHCSECPKVFYDAYMRNMHIRVQHKGERPFTCNYCEKRFTSSNSRYLHERRFHGAMPRIQRHTRGTEAANGLDKSLTEVKHEQMESVRHYCTYCTKSYATKYALNWHNNIHLGVKPFKCKYCEMGFYDPQSKLKHEVMRHNSKRPYECDICLKTFFVRTKFRDHERIHTGERPFSCEVCNANFRYRYNLYTHRYSKLHKANVQRLLSVEEPKMEICIKWTLCRTCTCETSDTAQLQSLFSDKSLAKQLLDYSGVAVDPNDGLPDQICKDCIHSLNAAHLFLVGCKRADEQLRNVVERTKSATKDFDSKSKRSRKAESTTSDDEDTTLPTKINIESKEMNVDEPEQLDMSKEEKKSIQSAADSAAQNNEEYLLVVSNKEEDSDCNEYIMVDVGDNDNVIEESDADDDFNKKNPSVKETIERTVDLGPACESANFSYHSCTICYNSFPNKTQLKNHVRKHCIVKNYECELCSKRFNAACNLTTHMRTHTGEKPFVCNYCGRRFADRSTHRKHERMHTNERPYACDICGKTFSLSTTLKAHALTHTKEKPHKCLTCKKGFRLPHQLKAHEKTHTHRYEVSITYDDYNQDEDDSASS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -