Dbus006582.1
Basic Information
- Insect
- Drosophila busckii
- Gene Symbol
- -
- Assembly
- GCA_011750605.1
- Location
- NC:8850035-8853264[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 1.8 1.1e+02 3.1 0.5 2 23 115 137 114 137 0.93 2 13 0.013 0.75 9.9 3.1 2 23 144 166 143 166 0.96 3 13 2.5e-06 0.00015 21.5 3.3 2 23 171 193 170 193 0.96 4 13 0.0081 0.49 10.5 9.1 2 23 426 447 426 447 0.97 5 13 4.3e-07 2.6e-05 23.9 3.3 1 23 453 476 453 476 0.96 6 13 0.0002 0.012 15.5 0.7 1 23 481 504 481 504 0.96 7 13 4.8e-05 0.0029 17.5 4.3 1 23 522 544 522 544 0.97 8 13 6.5e-05 0.0039 17.1 1.6 1 23 549 571 549 571 0.98 9 13 2.4e-05 0.0014 18.4 1.7 1 23 577 599 577 599 0.95 10 13 0.0011 0.068 13.2 0.8 1 23 605 627 605 627 0.98 11 13 2.5e-07 1.5e-05 24.7 2.7 3 23 635 655 634 655 0.99 12 13 1.7e-08 1e-06 28.3 1.0 1 23 661 683 661 683 0.99 13 13 1.1 68 3.7 5.2 1 19 688 706 688 711 0.88
Sequence Information
- Coding Sequence
- ATGCCCGACACGGACACAAATTTTGATGCAGAGCGCATCTGTCGCGTTTGCTTGAGAGCAGCGGATgtggatttttattttatatacgaTGAGACCCCTGTGGAGCTGGGCGCCAACATAGCCCAGATACTAAACGAATGTACGCGCTACACCTGCGAACGGTACGACAAAATGCCACACCATATGTGCGATACCTGCATCAAAGCCGCACGCCAGGCGTTTCGCTTTAAACGAGATGCCGAGCAGGCATATCGCTCCCTGGTTGCCACACTGGGTCGCACGCCTCTCATCAAGCCCAATAGCAGCGATGTTTGCACCCAGACGGAACAGCTGCCAATGCTGTCCTGCGGCATGTGCGATGACAAGTTCCTCAACATATACGAGCTCCGACTGCATCGGCAACGGCAGCACAAAGAGGCACAACACTTGAAATGTGAGCATTGTGAGGCGGAATTCCAGTCTGTACGACATCTGCGCAGTCATTTGCAGTCTCAGCATGATCAAGCGTCCAGCTGCCGCATGTGCCAACGTGTCTTCTCCAGGCGAGATCACTTGATGCGTCACTTACGCACTGTGCACAAGATAGACAATCCACGCCGGTCGTTAACTGAAGAGCAGCAAGGTAGTACAAGTTGGCCACCAGTGGACGAGGCGAGCATGCAATGTGATGATGAGATGGTGTTGCTGAATGATACTGGCTGCTCCGATGATAATATTGAGGATGGCTACGAGTGCCACACAAATCCCATATCAAGTAATGAAGAAGGCGATGAGGACGACGAAGCCGATGCCGAGGCTAAAGCAAACCTATGGCTGCACATCAAGCCGGAGCCagaactggagctggagcgaGATCGTGAACAGGAAGACAAACGTCGCAAGAGCACAAAAACAGAGCAAGAGCTGGAGTCGCCTAAAAATGTCAACAGCATGTTAAGCGCTGTGGAGGTCAAAGAGGAACCAGTAAGCAGCAGTGCGGAGCAGTTGCCGATTAAGCAAGAGCTGCACCTGATGCAGCATCGGCTTGACAACGCATCAGATCTGGAGGAAGACGATGAGGATCTGGAAGTAGAGGACGAAGAGGATTATCATTTGATGCACAGCACAGATGGCGAGCTAGACGAAAGCGATTTGGATGATACGCAATGCGCACAAGCCAAGCTCCAACAAAAGTCCACAGCGGACAGCTCTGGCAAGCAGCAGAGACAAAAACGTCGACGTCGAAgcaaacgcaacagcaacagtaacaacaacagctcacCCAATCCAGAAAATCGCTGCGATGTCTGCCAGCGCACATTCTCACGCCACTGCCATTTGCTGCGTCACAAGCTGTCGCATCTAGAGCAAAAGCCTCATAGTTGTCCGCACTGTCCCAAGGCTTTTGCGCGTAGCGACCATCTGAAGGCGCATATGACAAGTCTACATGGCAACAAGGAGCACAAATGCCAGATTTGCGAGGCAGCATTTTCGCGTGTCGACGCGCTGGAGCGCcataagctaagcaaacacaATGGCGAAGGCTTGGATGCCAACAGTGAGCTCAAGCTGCAGTTGAGCGAACACACCTGCGAATATTGCGCCAAGCGATTCAGCAGCAAGACTTATCTACGCAAGCATACGCTCATACATACAGAGTTTCTCTATGCCTGCAAGAGCTGTGATGAGACCTTCAAGGAGCGGCAACAGTTGCGCAACCATGAAAAGACCCACACGGGTCAACGCAACTttctttgctgcatttgtggTGATAGCTTTGCGCGGAACGACTATTTGCGCGTGCATATGCGTCGCCACAATGGCGAGAAGCCCTACAAGTGCCGCTTTTGCATCAAGGCGTTCCCACGTGCCACAGATCTCAAGGTGCACGAACGCTATCACACGGGGACGAAGCCCAATTTGTGCAACACATGCGGCAAGAGTTTCCATCGTGCCTACAATCTAACTATCCATATGCGTACGCACACCGGCGAACGTCCCTACAAATGCGATCAATGCCCCAAGAGCTTTAGCCAGAGCAACGATCTCAAGGCGCACATACGCCGGCACACAGGCGAACGCTACAAGTGTCCCCACTGCGATGCCTACTTTTTGCAATTGTATCACATGCGCAATCATTGCCTTAGCGCCCACAACAAGCACATTGAGACCAAGACGGGGCGATTGCAGCGCACTGGACTGCTGGATGAGCACAATCAGACGCATCTTACCACGGTGGTTATGCCGCCGCCTTCAGCGCCGGCTTCGTCATCCACACGCTTGCAACAAGTCGCTGCAGCGCTACCGACGTCTTCCTCTATTATGGAGGCGCCCTACAACAGCACCACCATTCCATCACCTGTATCCGCAGTAACGATGCCGCAGTCTTCCAGCTATGTGGAAACAgtgagtgcagcagcagccacgcccacagcaccGTTTGCTGCTTTCAGCATACCTCCTGCAGTTATGGCCCATCTCATGTACAATCATGGCGGTAACAGCCAGCAGAGCAGTGCAAGCGACACCGGTGACGTCAGCAAATAA
- Protein Sequence
- MPDTDTNFDAERICRVCLRAADVDFYFIYDETPVELGANIAQILNECTRYTCERYDKMPHHMCDTCIKAARQAFRFKRDAEQAYRSLVATLGRTPLIKPNSSDVCTQTEQLPMLSCGMCDDKFLNIYELRLHRQRQHKEAQHLKCEHCEAEFQSVRHLRSHLQSQHDQASSCRMCQRVFSRRDHLMRHLRTVHKIDNPRRSLTEEQQGSTSWPPVDEASMQCDDEMVLLNDTGCSDDNIEDGYECHTNPISSNEEGDEDDEADAEAKANLWLHIKPEPELELERDREQEDKRRKSTKTEQELESPKNVNSMLSAVEVKEEPVSSSAEQLPIKQELHLMQHRLDNASDLEEDDEDLEVEDEEDYHLMHSTDGELDESDLDDTQCAQAKLQQKSTADSSGKQQRQKRRRRSKRNSNSNNNSSPNPENRCDVCQRTFSRHCHLLRHKLSHLEQKPHSCPHCPKAFARSDHLKAHMTSLHGNKEHKCQICEAAFSRVDALERHKLSKHNGEGLDANSELKLQLSEHTCEYCAKRFSSKTYLRKHTLIHTEFLYACKSCDETFKERQQLRNHEKTHTGQRNFLCCICGDSFARNDYLRVHMRRHNGEKPYKCRFCIKAFPRATDLKVHERYHTGTKPNLCNTCGKSFHRAYNLTIHMRTHTGERPYKCDQCPKSFSQSNDLKAHIRRHTGERYKCPHCDAYFLQLYHMRNHCLSAHNKHIETKTGRLQRTGLLDEHNQTHLTTVVMPPPSAPASSSTRLQQVAAALPTSSSIMEAPYNSTTIPSPVSAVTMPQSSSYVETVSAAAATPTAPFAAFSIPPAVMAHLMYNHGGNSQQSSASDTGDVSK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -