Basic Information

Gene Symbol
hang
Assembly
GCA_011750605.1
Location
NC:15313736-15328953[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 0.24 14 5.9 1.0 3 23 270 291 269 291 0.93
2 18 0.3 18 5.5 3.2 3 22 398 417 396 417 0.89
3 18 0.00051 0.031 14.2 3.3 1 22 515 536 515 538 0.90
4 18 0.059 3.5 7.8 0.1 2 21 550 569 549 570 0.93
5 18 0.00059 0.036 14.0 0.2 2 23 698 720 697 720 0.95
6 18 0.0017 0.1 12.6 0.1 1 23 728 751 728 751 0.96
7 18 1.4e-05 0.00083 19.2 0.1 2 23 837 858 836 858 0.97
8 18 0.00024 0.015 15.3 2.9 2 23 953 975 952 975 0.97
9 18 0.019 1.2 9.3 0.2 2 23 984 1006 983 1006 0.95
10 18 0.0018 0.11 12.5 0.1 1 23 1019 1042 1019 1042 0.97
11 18 0.00011 0.0064 16.4 1.1 1 23 1088 1110 1088 1110 0.99
12 18 0.0017 0.099 12.6 0.9 1 23 1118 1141 1118 1141 0.96
13 18 0.058 3.5 7.8 0.4 2 19 1149 1166 1149 1167 0.94
14 18 6.3e-05 0.0038 17.1 0.2 3 23 1262 1282 1261 1282 0.97
15 18 0.0043 0.26 11.3 0.1 1 23 1317 1339 1317 1339 0.97
16 18 0.0005 0.03 14.3 0.6 2 23 1429 1451 1428 1451 0.93
17 18 0.0055 0.33 11.0 0.3 3 23 1507 1527 1507 1527 0.98
18 18 5.7e-05 0.0034 17.2 2.1 1 23 1888 1910 1888 1910 0.99

Sequence Information

Coding Sequence
ATGTGCGacgctgctgcggcagcgacagcCCAGGGATTGGGTGCGGGAGTGTCTGAGACatcagcgacagcgacagatGAACTAACGCGACAAAATAGTTGTCGCCTGTGCTTAGCGCCAGCCAGTGAATGCATTTCGATTATTAACAGTTATGCAGCCGATAAGGAGCCGCTGGCcactaaaatacaaaactgcGTGAATATCAAGATATCATCGTTGGACCGTTTCTCTTTGAACATTTGTCATGCCTGCATTAGCTATTTGAACTCGTGGCAGAGCTTCAAGAATCGCTGTCTGAGCTCACAGGCAAAGCAACGACAGTGGCAGGATATTGACAAGACCAAACAGCAGACGCTCTTGGGCTATTTGGACTTGAATAGAGCGGAAAATGGCAACGCACTGGAGCAGCaccaacatcagcagcagcagcatcaacaacagtCTGAAGCAGCATTGGCTGCAGCCGAGAAGGCATCCGCCAACATTTTGGATGGCATACCATCGCTGAAGAAGCGTAAATCCTTAACAGTCTATCCGCTGCCCGCTGTACCCATCAAGGATGAGCCACTGGATGATACGGATGATGACTATCACATGAAAAGCATTGATGAGTCCGATGACATGATGGACCCCACTATGTTCCTAGAACGCTCCGAGCATGAGGGCGATGTGCCGCTAATGACCTCCGACTATGACTATAGCGCGCAGCACGGCGTAACGGCGGCGGTGGCCGCAGCCGCAGTTGCACAACTGCCCGCCACTGCGGTGGCCAATGTGGCTGCCGCTGGTGACTCTAAGGTGGCCAGCTGCCGCGCCTGCAGTCTGCAGTTCTCAACGCGCGCCAATGCGCGACGCCACGAGCGCAACTTGCATCCAAATCTGTTTCAACTGTCCACAGATTCGCCCAACAATACGCCGATAACAAAGCCAACGCCAGCATTGGCCGCAGCGCTGGAAATTCAAcgcgcggcggcggcagcagcggccacAGCCGAGGCgaccaaagcagcagctggcggcaATATCTCTGCGCAGAAGTATCGCCAGGTGGTGATGAATACGTTCATCAAGTGCGAGAACGGCGGCTATGACTACGAGAATCCGGAGCAGTATCAGCAGCTGTTGACGCGCGAAAAAGTGGACTTCATAGATGAGAACAGTGAGTTCCTCGAGCAGTACCAAACGATGACCTGTCGCTGTTGCAACAAATACTTCAGCACCTATAAGAATTTCATGGCCCATGTGCGCAAGAAGTATCCAACATTGCCACGCAATCTGTGCTTCAACTGCCTCAAGATGAACGACTCCAAGGCGCTGTTCATATCGCATTTGAAGAAGCGCAACTGCATCAATCTTTATCGCATGCTCAATGGGCTGCGTGCCAAGCAGCCCAACTTTACGCCCagcggcgacaacaacagcagcggcagcaacttggaggcaacagcagcacagctgGCGGCGCCTGCCACGCCCAACGATTCCATCAGCTCCGAGCGTCCCGAGAAGTTGCGCGCCAAGGAGCTGCTGGTGAACAAGCTCTACGAATGCAAGCTCTGCCCCAAAGGCTTTCGCACCAAGCACGAGTTCCGCACCCACGTCTATGACAAGCATGCGGATGTGCAGCGCAAGGATAACAATTCCATACAGTGCAGCTTCTGTGGCCTCGACTTTGCCGATCCGGTGGACAGACGTCGTCACTACAACAACATGGACTGCATTGTGCGTCTGCGTTGCATGACCTGCGATGCCAAGCTGGAGACGCACCAACGCTTCCTCGAGCATGTCTATCAGGATCACTTGGgtggcgtcagcagcgacagcgcagCCACCAATGAGCACTCGCCCGGCAAGCGCAGTCTGCTGGGTGCGCTCGGCATTGGCGTCAGCCAGTCCAGCTCCAACGACAATGAGtcacgcagcagcggcagccagaacaacaacaacagcaccacAACACCGCTGACCTCCACGCCCAAGCCGAGCGGCAATGCAGCCACCAGCactcccgctgctgctgcaactggcgccagcgcagcaagcagcagtcgTGAGGCACCCAAGTCACAATACTTTTCACGCATGCCCCAAGTGTGCCCCATCTGTGGCCAGCagtacaacaactacaacaatgtGCTGCGTCACATGGAGTCAAAGCATCCCAACAAGCTGCCCGAGACCTACAAGTGCGTGCGTTGCGGCCTCGGCTATCCACGGATCTCCTATCTGCGCGAGCATATGATCAACGTACATGGCGTGGACAAGAATCGTCACTCTGGCGGCTTTGAGTACATCGTTAATGCGGATGCAGTCAAGTTGGCCGATGGCAGCACGCCCAATGTCTATACGGGTCGTTATGATTATGTGATGAAGGATTTGATGTCCATAACAAATGGTGGGACAATCGatgatgaggatgaggaCACTGGCAACATTGCCAAGAAAATGCGTCTGGacgagagcagcaacaacagcagcatcaacacCAGCATTGCCAACCAGCAGAAGGAGTGTCCCATCTGCAATGCCGTGTTCAGCAACAATATTGGGCTATCCAATCATATGCGCTCCCATTACACCGCATCGACTGCCACAAATGCCGCACTGGCTGCAGCTAATCGCATGACACCCAAATCGCTGACCATAACAGCAACGCCAGCAGTggaggcaacagcaacaagcacatcagcagcagcagcagcagcagccgcatcagTGACAatcattgcagcagcagcaactagagctggagctgatGGTGCAGTGCCGCCTGCAATGGCCAATCAAACGGCACAGGAGCAAGCTGTGTTCCGGCGTAGCTTGGATCAAGCTGCTGATCGACGCTTTAGGCGCATGCGCTGTCGCATCTGCCAGCGCAGATTCAGCTCCAAGAAGTCCTACCGCTATCACATGCTCACCGATCATCAGGTGCAGAATGTGCAGTTCATCAAGTGCAAGCTCTGCAATGCGGAGTTTGCCTATGAGAAGGGTCTGAAGGTGCATCTGTTCAAGGTGCACGGACGCGCGATTAAGGATGAAATGATTGTCAAGCAATTCGAGTGTGATGTCTGCTCGATTGTCTATAGCtcggagctggagctgcagcagcataagcGCAGCGTGCACAAGTCCCAAGTGGTCCTGGACACTGGCGCCAAATCGAGCAAGAGCTCCTCTGCTAACGCTACTTCAAATGCTGACCTGGCCAACAGCgatgctgccgccgccgccgccgcttcgGCATCGCTGCCTTTGTACTGGTATCAATGCAAGTACTGCCCATCCAACTTTAATACCAACAAGAAGTTGGCCATACACATTAATTCCCATGATGAGTTCGATTCGAATGATTATTCCTGCAAGGACTGCGGCAATGTCTACAGCGGACGCAAGAGCCTCTGGGTACATCGCTATAAGAAGCATCCGCAGGTACCGGATCCGGCTGAGTGCACGCTGTGCCGCAAAATGTTTTTCGATCGCCAAATGCTGGAGAATCATACGCCCACCTGCAATCGCAAGCCGATTACGGCAACGGGCGCACATCAGCAACAGGAACAGGGACAACAACTGCTGTcggcgtcgcagcagcagcagcgcgcggTGTTCAAGCACAAGACgggcgatgatgatgacgatgaggAGGACGATGATCAGCTGCTGATGCTTGACGGTGCGGGAAGCGATAGCAATGGCGGCGCCAACACCAACACGCACACCACAACCACAACCACCAGCAACACCATAAGCACAAATAAGATTAAGATACGCATGCCGGAGGTGGCATGCACCATTTGTGGTGCACGCTTTACCGATCAGGAGATGTTCGAGAAGCATATTGAGAAGCATGAGCAGGAGCTGTATGTGGATAATCCGCTGGCAGCGATGTTTGACGATGGTCCCGCAGATGCGGGACAATTTCAGGTGGAGCGACAGAATGAGAATGGGGAATATGCGTGCGATTTGTGCGCAAAGACGTTCCCCCAGGTGATTGCACTGAAGGTGCATCGCAAGTGGCATTTCAGAGGTGATAGCAAGCAGAATCTCACCAACGACAGCGAAGCGACGCAGCTGAACAGtctcagcaacaacaacaacaacaacaacaacaattcactGAGCAATTCATCCATGTTGCAGCTGCGGGAACTGCATGCAGTGGGTCTCATGCccaatcagcaacagcaacagaagcaacagcagcagcaactgcaacagaacagcaacaacaacagctcgagcagcagctcagcggCCAACAAATCGCTGAAGCGCAAACGTGAGCTTAAGTGTGAATACTGCGCCTCCACctttataagcaacaacaatctgcGTCGCCACATGTACGAGCTGCACAAGCATGAGGTCAGCAATCTGCCAGAGCCGCCAGTTATCGAAGTGGACGAGGCCTTATGTTGTCGTCGTTGCGGTGATTTACGCTTCGAGTCCAAAGAGCTCTGGATCGAGCATAAGCTAGCGGACGCCAAGGTCGTTCGTCCATTCTGTCCATTCCAGTGGGGCTGTGATTTATGCGGCGAGTACTTGTCGCGCAAAGAGAAGCTTATCAATCACATAAACAATCATCTCAAGGAGGATGTCATTGTGCCAGTGGCAACCAAACCAATGGCCACGGCCAAGAGTGCGAGCACAGCCAAAGCAAcgccaccagcaacagcaatacaagctgaggcagcagcaacaacaatagcagcagtagctacaaaaacagcaacaacaacaacggcaacacCAACGGTCATAACTAAAGCTATAAAGCAAGAAGAGCAAACTGATGAGGATGagcaggcagcggcagtgacagcaacagcaacagcaacatcaacagctgctgctggcagtaaAGAGAAGCTTGAGAAGCAAGCGGCAGCGCTCAAGTTGGGTGAGAGCGACTTGGATGAGGAGGACAGCGATTTAGATAGCGAGTTGGATGCGGAGGATAGCGATTTGGATGAAGATGATAGTGAGTTGGATGAGGAGATCGAGGACAAcagcgatgatgatgaagacAGCTCCGATTTGGACGACCTCATTGAGGAGGTGGAGGTGGAAGAGGTCGACGATGACGGCATTGTGGACGATGATgataattttgaatataacgCCAAGCAGCTGAATGGCAAtgacaacaaacagcagcagcagcagcagcaagcaaaacaaaagcaacatcagcagcagcagcagcaggcgaaacaaaatgaattgctGGTGCTGCATAGCTCGGAGGAGGACGTAGATGACGTAGATGATGATGAGGCTGAGGCCATTGAGAGCGACAGTGACGATGATCTTGAGTTTGTCGATGATGCTGAAGGTGACGCCGAAGATGATGGCGTGGGTGAGTCCATGACAATTGATGATATAATCGAAGAGGATGAGGAAATGCCGAGctcaacatcagcagcagggTCGGGGGGTGGTGGTCGTCTGGCCAGCGCCAGGGGCGGCAGGGCCAGAGTCAGAATGAGCGCTAGCAGCAATGGTGATGCTGATGGTGATGGTGatggcgatgatgatgatgattcaTCCTCGTCGGAGAGTgaatcaacaacaacgacgcATTCAACTGGTGAGCGGCGCAAAAAATCTgtagcagcatcagcaacggCACATGGTGCTGCCGCTGATCAGTCTCATTCCAGCTATACGTGTGATCTATGTCAACTTTGTTTCGATTCTCAGGAGCTTCTGCAGACTCACATTAAAAGCCATTTTCTGAATAATGGGCCCAaggcagcgagcagcagcagcagcagcggcgctagcaacaacaacaacaacaatagcagtagcaacaatagcagcagcggcagccataGCCACAGCAaatccaaaagcaaaaagtccAGCATACtggaaataaaaacaacaaagacgACATCAGCGtccgcatcagcagcagctgcagcagcgacgggCTCCAACTGA
Protein Sequence
MCDAAAAATAQGLGAGVSETSATATDELTRQNSCRLCLAPASECISIINSYAADKEPLATKIQNCVNIKISSLDRFSLNICHACISYLNSWQSFKNRCLSSQAKQRQWQDIDKTKQQTLLGYLDLNRAENGNALEQHQHQQQQHQQQSEAALAAAEKASANILDGIPSLKKRKSLTVYPLPAVPIKDEPLDDTDDDYHMKSIDESDDMMDPTMFLERSEHEGDVPLMTSDYDYSAQHGVTAAVAAAAVAQLPATAVANVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSPNNTPITKPTPALAAALEIQRAAAAAAATAEATKAAAGGNISAQKYRQVVMNTFIKCENGGYDYENPEQYQQLLTREKVDFIDENSEFLEQYQTMTCRCCNKYFSTYKNFMAHVRKKYPTLPRNLCFNCLKMNDSKALFISHLKKRNCINLYRMLNGLRAKQPNFTPSGDNNSSGSNLEATAAQLAAPATPNDSISSERPEKLRAKELLVNKLYECKLCPKGFRTKHEFRTHVYDKHADVQRKDNNSIQCSFCGLDFADPVDRRRHYNNMDCIVRLRCMTCDAKLETHQRFLEHVYQDHLGGVSSDSAATNEHSPGKRSLLGALGIGVSQSSSNDNESRSSGSQNNNNSTTTPLTSTPKPSGNAATSTPAAAATGASAASSSREAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGLGYPRISYLREHMINVHGVDKNRHSGGFEYIVNADAVKLADGSTPNVYTGRYDYVMKDLMSITNGGTIDDEDEDTGNIAKKMRLDESSNNSSINTSIANQQKECPICNAVFSNNIGLSNHMRSHYTASTATNAALAAANRMTPKSLTITATPAVEATATSTSAAAAAAAASVTIIAAAATRAGADGAVPPAMANQTAQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGRAIKDEMIVKQFECDVCSIVYSSELELQQHKRSVHKSQVVLDTGAKSSKSSSANATSNADLANSDAAAAAAASASLPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPDPAECTLCRKMFFDRQMLENHTPTCNRKPITATGAHQQQEQGQQLLSASQQQQRAVFKHKTGDDDDDEEDDDQLLMLDGAGSDSNGGANTNTHTTTTTTSNTISTNKIKIRMPEVACTICGARFTDQEMFEKHIEKHEQELYVDNPLAAMFDDGPADAGQFQVERQNENGEYACDLCAKTFPQVIALKVHRKWHFRGDSKQNLTNDSEATQLNSLSNNNNNNNNNSLSNSSMLQLRELHAVGLMPNQQQQQKQQQQQLQQNSNNNSSSSSSAANKSLKRKRELKCEYCASTFISNNNLRRHMYELHKHEVSNLPEPPVIEVDEALCCRRCGDLRFESKELWIEHKLADAKVVRPFCPFQWGCDLCGEYLSRKEKLINHINNHLKEDVIVPVATKPMATAKSASTAKATPPATAIQAEAAATTIAAVATKTATTTTATPTVITKAIKQEEQTDEDEQAAAVTATATATSTAAAGSKEKLEKQAAALKLGESDLDEEDSDLDSELDAEDSDLDEDDSELDEEIEDNSDDDEDSSDLDDLIEEVEVEEVDDDGIVDDDDNFEYNAKQLNGNDNKQQQQQQQAKQKQHQQQQQQAKQNELLVLHSSEEDVDDVDDDEAEAIESDSDDDLEFVDDAEGDAEDDGVGESMTIDDIIEEDEEMPSSTSAAGSGGGGRLASARGGRARVRMSASSNGDADGDGDGDDDDDSSSSESESTTTTHSTGERRKKSVAASATAHGAAADQSHSSYTCDLCQLCFDSQELLQTHIKSHFLNNGPKAASSSSSSGASNNNNNNSSSNNSSSGSHSHSKSKSKKSSILEIKTTKTTSASASAAAAAATGSN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-