Dbus008423.1
Basic Information
- Insect
- Drosophila busckii
- Gene Symbol
- Zbtb41
- Assembly
- GCA_011750605.1
- Location
- NC:12381272-12383582[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.018 1.1 9.4 3.8 2 23 238 259 237 259 0.96 2 12 2.9e-05 0.0017 18.2 0.9 1 23 265 290 265 290 0.95 3 12 3.9e-05 0.0024 17.7 1.6 1 23 297 322 297 322 0.96 4 12 6.3e-05 0.0038 17.1 1.3 1 23 332 354 332 354 0.97 5 12 0.00014 0.0083 16.0 0.9 3 23 363 383 362 383 0.97 6 12 0.00064 0.039 13.9 0.2 1 23 389 411 389 411 0.97 7 12 0.035 2.1 8.5 5.9 1 23 417 440 417 440 0.96 8 12 2.9e-06 0.00017 21.3 1.1 1 23 446 468 446 468 0.97 9 12 7e-06 0.00042 20.1 0.1 1 23 474 496 474 496 0.99 10 12 9.8e-07 5.9e-05 22.8 1.1 1 23 568 591 568 591 0.96 11 12 0.02 1.2 9.2 0.2 3 23 599 619 598 619 0.96 12 12 7.7e-08 4.6e-06 26.3 1.1 1 23 625 647 625 647 0.97
Sequence Information
- Coding Sequence
- ATGGATGAAGGGAGAGCATACTACATACACACGTTATGTCGCATCTGCCTGAACCACCTAGAAAATGATGCCGCCTATGGACTATTCCTGGTGTCAGGCTTGGCCAAGAAACTGTGTGTATGCACCTCTCTGTCAGTGGAACTGGACGATGGTTTCCCAGAAAACATTTGCACCAGTTGTTTCAGCAAACTTGACGACTTGCACAACTTTCAAAAGATGTGCGTGGACTCAGTGCAGAAGTTCAACGATATGGTGGCCAGCAACTGCTTTGATTATAATACGCCCTCCATGAATTGCGTTAATGTACTCAATGTTGCAACGCATGATACAGATATAGCCGAGGAGGAATACGACTGCAACTTTGATCCATGTTTAAATACCAAAATAGAAATAGTTGAGAGTGAGGACCATTTATTAGACAATTCTGAGAATGAAGACAAAGAATTTCAGGTCGAGGATAAAAGTTCTTCTATTCATAGCGATGGTGACGTTGATGATGGAAATGTGGATTTTGAAGTGAGCAGCAGTGAATCCGAGCAAGACATGGTCCTATCACAATTGCGCAACAGTGCTATTtccaaagcaaaacaaaaggcagaAAAGAGTACTCATAAAGACGAAACAGATGATTCTTCAGGTGATGACAATGATAAGGGAAGCACAAAAGTAAAACGCATCTCGGTACCTGAACGCTATCGACATACACTAATCGAATGTCACGTTTGCAATCAGAAGTTTAAGGAGGCATTTCGCTATGAAGAGCATATGAAACACCATAACGATTTGCTACCATTCCAGTGCGAGGTGGAGACCTGTAAAAAGAGCTTCACAACAAATGGTGGGTTACGACTGCATATGGAACACGCTCATCCTGAACTCGTCAAGGCGTATCCCTGCACAGTTGAAGGCTGCGATAGGACATTTACGCGCACCCACAAGCTAACGAACCACCTAAAGAATGTGCACAGCATAGTAAAACCGAAGATAAAAGAATTTCCGTGTCCAGAATGTGACAAGGTGTTTCAGTGCCCAACGGCACTTAAGAAGCATATGTATAAGCACACAGGAGAGGAGTTTCCCAATGCCTGCGAGCACTGTGGCAAACGTTTCTTTATTCAAGCCGAGTTGCGCGATCATCTACTGCGCCATGCTGGTATCAAGAATTACGAATGCCCGCATTGTGGCATCGGAAAATACACTCAGTCTGAATTAAACAAACATGTGGCAATTCACAATAGAGTAAAACAGTTTCACTGCAGCCAGTGCAATCATTCGTCTTACAGCAAGCATGCGCTAAATAACCATGTTAAAGTGGTGCATCTAAAGATTAAAAAGCACGTCTGTCAGCAGTGTGGAAAAACATTTGGCAAGCCATATAGCTTAAGAGCCCATCAAGCGCGACACACAAACGAGAAAGCTTACGTTTGTAATATTTGTGGTATTTCCTATGCCGCTAAGAAAAGCTTAGTTCGACATTTACAAACTCACGAGAATTCCGAGACAACGGAGGAGGAGCCCACAACAACTATTGAAGATCAGCAATTAACACCACTGGCAGACGACAATAAACCAAAACTTATGATATCTCCTCAGCCTCAAAGTTCAAACAAACTCCAACATGTGGATGTGCCACAGCTAACTGGCGCCGTTGGTAGTCCAGTTTCATTTCTATCTATAGGAGCCACAAAAATAGGTGATAAATTCATATGCCCTGGCTGTGGCAGAGGCTTTAATCACAAGAGCAATATGAAAATCCATTACAGGAACATACACGAAAAGGTCAAAGATCAAGCTTGTCGCTTTTGTCCAAAGCGATTTGCCGTTGTGCAGACGCTGCGCAACCATGAATTAATCCACACAGGCGAGAAGCCATTTGATTGCAACATATGTGGAAAGGCGTTTCGTCAGAAGCTGAACTTGCAGACCCATTTAAAAACGCACAATAAGCCACCAAAAGCACCAAAGAAGGAAAATACAAATGTGTCACCAAATTTTGAGGAAAACAAGGTACCGGCGGCTGATATTGCGACCTCCTCAGCTACAATGGATGGTGAAGAAATGATTGAAAACgacataaaaatcaaaatagagAACGAGGCTTAA
- Protein Sequence
- MDEGRAYYIHTLCRICLNHLENDAAYGLFLVSGLAKKLCVCTSLSVELDDGFPENICTSCFSKLDDLHNFQKMCVDSVQKFNDMVASNCFDYNTPSMNCVNVLNVATHDTDIAEEEYDCNFDPCLNTKIEIVESEDHLLDNSENEDKEFQVEDKSSSIHSDGDVDDGNVDFEVSSSESEQDMVLSQLRNSAISKAKQKAEKSTHKDETDDSSGDDNDKGSTKVKRISVPERYRHTLIECHVCNQKFKEAFRYEEHMKHHNDLLPFQCEVETCKKSFTTNGGLRLHMEHAHPELVKAYPCTVEGCDRTFTRTHKLTNHLKNVHSIVKPKIKEFPCPECDKVFQCPTALKKHMYKHTGEEFPNACEHCGKRFFIQAELRDHLLRHAGIKNYECPHCGIGKYTQSELNKHVAIHNRVKQFHCSQCNHSSYSKHALNNHVKVVHLKIKKHVCQQCGKTFGKPYSLRAHQARHTNEKAYVCNICGISYAAKKSLVRHLQTHENSETTEEEPTTTIEDQQLTPLADDNKPKLMISPQPQSSNKLQHVDVPQLTGAVGSPVSFLSIGATKIGDKFICPGCGRGFNHKSNMKIHYRNIHEKVKDQACRFCPKRFAVVQTLRNHELIHTGEKPFDCNICGKAFRQKLNLQTHLKTHNKPPKAPKKENTNVSPNFEENKVPAADIATSSATMDGEEMIENDIKIKIENEA
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -