Basic Information

Insect: Drosophila busckii
Gene Symbol: zfh1
Assembly: GCA_011750605.1
Location: NC:11680219-11685933[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 2.1e-05 0.0012 18.6 1.1 1 23 154 176 154 176 0.97

2 15 0.00064 0.038 13.9 1.2 3 23 184 204 182 204 0.94

3 15 7e-05 0.0042 17.0 0.1 1 23 353 375 353 375 0.98

4 15 0.00066 0.039 13.9 2.2 1 23 381 403 381 403 0.98

5 15 1.3e-05 0.00075 19.3 4.8 1 23 434 457 434 457 0.97

6 15 0.00026 0.015 15.2 0.5 1 23 482 504 482 504 0.94

7 15 0.014 0.85 9.7 1.5 1 23 510 533 510 533 0.97

8 15 0.021 1.2 9.2 0.4 3 19 542 558 541 559 0.95

9 15 0.00012 0.0073 16.2 5.6 1 23 568 590 568 590 0.97

10 15 0.43 26 5.0 1.6 2 23 596 617 595 617 0.96

11 15 7.2e-06 0.00043 20.1 1.0 1 23 626 648 626 648 0.98

12 15 0.00081 0.049 13.6 0.1 3 23 656 676 654 676 0.97

13 15 4.3e-05 0.0026 17.6 0.5 1 23 682 704 682 705 0.95

14 15 0.033 2 8.6 0.3 1 23 715 737 715 737 0.97

15 15 0.00027 0.016 15.1 0.3 1 23 1225 1247 1225 1247 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	2.1e-05	0.0012	18.6	1.1	1	23	154	176	154	176	0.97
2	15	0.00064	0.038	13.9	1.2	3	23	184	204	182	204	0.94
3	15	7e-05	0.0042	17.0	0.1	1	23	353	375	353	375	0.98
4	15	0.00066	0.039	13.9	2.2	1	23	381	403	381	403	0.98
5	15	1.3e-05	0.00075	19.3	4.8	1	23	434	457	434	457	0.97
6	15	0.00026	0.015	15.2	0.5	1	23	482	504	482	504	0.94
7	15	0.014	0.85	9.7	1.5	1	23	510	533	510	533	0.97
8	15	0.021	1.2	9.2	0.4	3	19	542	558	541	559	0.95
9	15	0.00012	0.0073	16.2	5.6	1	23	568	590	568	590	0.97
10	15	0.43	26	5.0	1.6	2	23	596	617	595	617	0.96
11	15	7.2e-06	0.00043	20.1	1.0	1	23	626	648	626	648	0.98
12	15	0.00081	0.049	13.6	0.1	3	23	656	676	654	676	0.97
13	15	4.3e-05	0.0026	17.6	0.5	1	23	682	704	682	705	0.95
14	15	0.033	2	8.6	0.3	1	23	715	737	715	737	0.97
15	15	0.00027	0.016	15.1	0.3	1	23	1225	1247	1225	1247	0.98

Sequence Information

Coding Sequence: ATGAACAATCAGGACTATGGCGGCATCCAGTGGATACAGCAGCATGCGTCGGCCGTCGACTCCGAAGCAGATACAGATATGCTGGAAAACGACGACGCAGACGCTGGCGAGAGTGAGGTGACTGCCGCCTATTTGGTGAACAACGCCACCGATGAGGACCTTGACCATATGGCAGCCGAGAATCTCATATTCATGGCACGCGATGGTCAGCTAAGTGAGATTATAGCTGCCAATGATGGTGGCGGCGGCACTGTGCTCATAACAGACAGCGGTACTGTGGAATATGCAGAGTCATTTGACGATGACGCGCAAGTGGTCACCGAGGAGGTCATCACAGATGATTGGGTGCAACACCAGGGCGCAGAGCGTGTGGAAATTGCAGCGGAGCAAATAGCTGGCACCAGCAGCTCACAAGAGCTGCTAGACATGGAGCAAGATGAGTACACAGCGCTGCGTCCGTATCCCTGTGATTTTTGCAGTCGACGCTTTCGCAAAAAGGGCAGTCTTAATAATCATATGCTGGCGCATCAGAACGATCGCCCGCATTTGTGTAAACTGTGTGGTGCGCGATTTTCGCGTCGCGGTGAGCTCATCAGCCATTTCAAAGCGCACGCTGAGGCTCAGGACGCGGCAGAAGCGGAAGCCATTGAAGAGCCGGCCATTAAGTttgagccgcagcagcagagacagTTGGATGATCACTACTACGAGCATGAATGGCAGCTGTATCaggagcagccgcagcagtcggagcaacaacaagaacagttTGTGATGGACACGCCAGAGGCGAGCTATGCCACAGAGACCCCTGAACCGGAGCCTACACCAACGCGCGGGCGTATAAGCCGACTCAAACTGAAGCAGGAGAGCACGCAGTACATAGTTATCAGTGAGAAGCAGGCGGAAGATATGCAACAGTATATGGACAGCGAGGAACAATCATCGGCGGGCTCTCAAACCACAGTCAGCAATGTGACGACGATTAAGGAAAACGAAGAAGTTGTAGTAGCTAAGCAAGAGCCACGCTATCCCGTGATAGATGATAGCAAACCGTTTGTTTGCCAGCAATGTGGCCTAGCATTTGCACGTGAGAAGGCGCTTGTTTCCCATATAAAGAATCATCGTGTGGATTCGCCCTTTGAATGTAATCAATGCCAGGAAATGTTCTGGGACAATCATAGCCTGCAAGAGCATCAGAAAACTCATCAATTCGAGGAGAGCAACTCGGAATATGATCCAGCCTCGGCGTGTGACGATAGCGCCAGTGAATCAGAGCCGGATCAGCTCTATGGCGATTATTATTGCAATGAGTGCGGCATTTGCTTTCATCGTCAGGATCTGCTGCGACGCCacatcaagcagcagcataagcaatCGACAGCGCTGGAAGATTCAATGCATGCGACTCCAGAGCATGTGGAGAATGCCAAAGATGCCACGCATTGCTGTGACACATGCGGCAAGTCCTTTCCCAGCCCGCTGGAGTTGCTTGCCCATGCGGAAATTCATGCACGCTTCCCGCCTTTTAAATGCGTTCTATGCGgcgtttgtttttatgaaGAGCAAGCGATTAAGCGACATTTGAGCACACGCCATCCGAATGAGCTGAAGCCCAACTCCTGCGTGCTGTGTGGCAAAGAGTGTCGCGATCGCAAGGCGCTCATTAAACACGCCTGGGATCATTCGCGAGAGAAGTGCCACTCGTGCTCCAAGTGCGGCAAGAACTTTCATAACAAAGCGCGTCTGAAGCGACACATGGCCTCGCATCGTGATAAGTCCGTGACATGCGAGGTGTGCCATGGCGAGTTTCCCGACGGACGCACACTCTCCAATCATCGACACTCGCATAGCACCACCTCGCCGGGCAAATTGTTTCCCTGCCACGAATGCGGCAAGACCTTTGGATCGCGCAGCTCGCAGCAAATTCATGTGCGCATACACACGGGTGAGCGTCCCTATGGCTGTCGATATTGCTGGAAGGCGTTTGCCGATGGCGGCACCTTGCGCAAGCACGAACGCATCCATACGGGCGAGAAGCCCTACGCCTGCTCTGTTTGTCCGCGCGCCTTTAATCAGCGCGTAGTGCTGCGTGAACACATACGCTCCCATCACTCCGGGCTGGATACAGTGCGTGGCACCTATCACTGCACTGTTTGCGAAGCGGACTTGACCTCATCTAATGATCTAATACAGCATCTCATCCAGCACAGTGATACGAACACCGCCAAACAGCGACAGCCCATTACTGGGCCACGTAAGTACAAACGTCGACGAAAACTGCAGCCGCATGAGATTGCGCACATGCGTGCCGAGCACAAGGAGAGTGAGGATTATGGCAGCGACATTGACATGTGTGACTTTGATGTGGAGAATGCCGATGAGATTTTCGACATGGTCGAGCCAACCACACCCAAGAAGGAGAAGCGTAAGCGCAGTGCCAGCAATCAAGCCAAGGCTGTAAGCAATGGCGAAGCTGCCAACACAACCACAGTGCCTGTCAAAGAGACGCCTCAATGGGAGGCAGCCAATGCGAATATCTTTCAAATCGATACGCTTGTGATGGTCAACGATACCACGCTGCAGCCTGTAAGTTCATCCACCAAGACGCGACGCGgcgccaagcagcaacagcagacgcCAGCTGCAGAGCCTAAATCAGCTGAGAAGCCCAGTGTCTCctccaccaccagcagcagcagcagtcgcagcagcagcagccgcaagaAGTCGAGCAAGTCGGCCAAGTCGGCAACTcctgcagctggcagcagcactcGCCCGCGCATGATACACACAGAGAAGTCGCGTGTGCCGGCGGCAGAGAGTGCATCGAAGAGGACGCGCAAGACTTATATAACGCGCAGTGAATCCAGCCAGCTGGGTCTGGTCAAGTCCACTGGCGTTGGCAGTTCGCGCATGGTGGATGACTATGAAATCATTTCGCCCGCCACACAGCCACCCAATCAGATCAGTTCCAGTCCGCTGCACATcaagcaggagcaggagcaacaacagcagcaacagcgggtGCAGCTCATGTACGATGATACACATTTGCTCATCGATGCGGCCTTGTTGCGTGATAAGACCTACGAGAAGTTCAATCCCAGCATTGTTAATGATCTGGAGGAGATTTTGCGTAGCCCGCTTAAGCATGATCGCAATGCACGTCTGCGTTTCACTAGCGAATCTTCTACCACGCCACAATTTCTGCCCGAGGAGGAACAAAATCTAATCAAAATTGAACCCACATCGCCGGATTTGCGTGATATGGTCGAAAGTCAGCAGCGTGTGTCGGCATCCAGCAACACGCCTACATCTTCGGCCTCGCCTTCAACAGCGGCGCGCACCTCACGCCATTTACGACAACTGACTGCCAACTCGAGCTCACGTGCTGCCTCCaagcgcaacagcaaagcTACAAGTGCACCCAGCTCCAAGAAGTCTAACTCCTCCAGCAGTTCATCCTCGACTGTGGCCGTTAACAAAGCCAACTCATACCTCAGCTACGGCGTGGATTCATACAATGTAAGCGTTGCAGCCAGCGCCAATTCTTCGGACGTTAGCTCAGGTTTCTTTTCCATCTCCGAAGTGGTGTCAGCTGCGGATGCGGCAGATGCAGCGGCCAAAGCTGCTGCGGCACAGAAGCCGGAGCGTCGTACGCGCTGCTTTGAGTGCGAAATGTGTTCAGCTAAATTCCCAGATCGTGCCCAGCTACTGGatcatatgcatatacacatttaa
Protein Sequence: MNNQDYGGIQWIQQHASAVDSEADTDMLENDDADAGESEVTAAYLVNNATDEDLDHMAAENLIFMARDGQLSEIIAANDGGGGTVLITDSGTVEYAESFDDDAQVVTEEVITDDWVQHQGAERVEIAAEQIAGTSSSQELLDMEQDEYTALRPYPCDFCSRRFRKKGSLNNHMLAHQNDRPHLCKLCGARFSRRGELISHFKAHAEAQDAAEAEAIEEPAIKFEPQQQRQLDDHYYEHEWQLYQEQPQQSEQQQEQFVMDTPEASYATETPEPEPTPTRGRISRLKLKQESTQYIVISEKQAEDMQQYMDSEEQSSAGSQTTVSNVTTIKENEEVVVAKQEPRYPVIDDSKPFVCQQCGLAFAREKALVSHIKNHRVDSPFECNQCQEMFWDNHSLQEHQKTHQFEESNSEYDPASACDDSASESEPDQLYGDYYCNECGICFHRQDLLRRHIKQQHKQSTALEDSMHATPEHVENAKDATHCCDTCGKSFPSPLELLAHAEIHARFPPFKCVLCGVCFYEEQAIKRHLSTRHPNELKPNSCVLCGKECRDRKALIKHAWDHSREKCHSCSKCGKNFHNKARLKRHMASHRDKSVTCEVCHGEFPDGRTLSNHRHSHSTTSPGKLFPCHECGKTFGSRSSQQIHVRIHTGERPYGCRYCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSGLDTVRGTYHCTVCEADLTSSNDLIQHLIQHSDTNTAKQRQPITGPRKYKRRRKLQPHEIAHMRAEHKESEDYGSDIDMCDFDVENADEIFDMVEPTTPKKEKRKRSASNQAKAVSNGEAANTTTVPVKETPQWEAANANIFQIDTLVMVNDTTLQPVSSSTKTRRGAKQQQQTPAAEPKSAEKPSVSSTTSSSSSRSSSSRKKSSKSAKSATPAAGSSTRPRMIHTEKSRVPAAESASKRTRKTYITRSESSQLGLVKSTGVGSSRMVDDYEIISPATQPPNQISSSPLHIKQEQEQQQQQQRVQLMYDDTHLLIDAALLRDKTYEKFNPSIVNDLEEILRSPLKHDRNARLRFTSESSTTPQFLPEEEQNLIKIEPTSPDLRDMVESQQRVSASSNTPTSSASPSTAARTSRHLRQLTANSSSRAASKRNSKATSAPSSKKSNSSSSSSSTVAVNKANSYLSYGVDSYNVSVAASANSSDVSSGFFSISEVVSAADAADAAAKAAAAQKPERRTRCFECEMCSAKFPDRAQLLDHMHIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -