Basic Information

Insect: Drosophila busckii
Gene Symbol: -
Assembly: GCA_011750605.1
Location: NC:14299656-14302876[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 7e-06 0.00042 20.1 0.4 1 23 219 242 219 242 0.95

2 16 0.00022 0.013 15.4 1.9 1 23 249 271 249 271 0.98

3 16 6.4e-05 0.0038 17.1 0.8 1 23 415 438 415 438 0.97

4 16 0.044 2.6 8.2 0.6 1 19 445 463 445 466 0.92

5 16 0.01 0.61 10.2 4.9 1 23 475 497 475 497 0.95

6 16 4.8e-05 0.0029 17.5 0.8 1 23 504 527 504 527 0.97

7 16 7.2e-05 0.0043 16.9 1.1 2 23 535 556 534 556 0.96

8 16 0.00056 0.034 14.1 0.1 2 21 583 602 582 603 0.94

9 16 0.0032 0.19 11.7 1.9 1 23 659 682 659 682 0.96

10 16 0.03 1.8 8.7 1.4 1 23 719 742 719 742 0.94

11 16 0.00011 0.0065 16.4 1.6 2 23 779 801 778 801 0.95

12 16 0.00068 0.041 13.8 0.3 1 23 815 837 815 837 0.95

13 16 7.4e-05 0.0045 16.9 1.8 1 23 843 865 843 865 0.99

14 16 2.8e-07 1.7e-05 24.5 2.6 1 23 871 893 871 893 0.98

15 16 9.2e-06 0.00055 19.7 3.8 1 23 899 921 899 921 0.97

16 16 0.00075 0.045 13.7 0.4 1 23 927 951 927 951 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	7e-06	0.00042	20.1	0.4	1	23	219	242	219	242	0.95
2	16	0.00022	0.013	15.4	1.9	1	23	249	271	249	271	0.98
3	16	6.4e-05	0.0038	17.1	0.8	1	23	415	438	415	438	0.97
4	16	0.044	2.6	8.2	0.6	1	19	445	463	445	466	0.92
5	16	0.01	0.61	10.2	4.9	1	23	475	497	475	497	0.95
6	16	4.8e-05	0.0029	17.5	0.8	1	23	504	527	504	527	0.97
7	16	7.2e-05	0.0043	16.9	1.1	2	23	535	556	534	556	0.96
8	16	0.00056	0.034	14.1	0.1	2	21	583	602	582	603	0.94
9	16	0.0032	0.19	11.7	1.9	1	23	659	682	659	682	0.96
10	16	0.03	1.8	8.7	1.4	1	23	719	742	719	742	0.94
11	16	0.00011	0.0065	16.4	1.6	2	23	779	801	778	801	0.95
12	16	0.00068	0.041	13.8	0.3	1	23	815	837	815	837	0.95
13	16	7.4e-05	0.0045	16.9	1.8	1	23	843	865	843	865	0.99
14	16	2.8e-07	1.7e-05	24.5	2.6	1	23	871	893	871	893	0.98
15	16	9.2e-06	0.00055	19.7	3.8	1	23	899	921	899	921	0.97
16	16	0.00075	0.045	13.7	0.4	1	23	927	951	927	951	0.91

Sequence Information

Coding Sequence: ATGAAGCTGCCGGTCATGTGTCGCACCTGCGATGCAAGGGAGACAGATAAGCTCTATAAACTAACTACTCCCACTAAAAAGTTTCCAGACAAACTTCTGTCTGACATTTTAACCGAACTAACTAACATTGAGTTGGACACTAGATTGGCGCAGCAGTTGCCACAGAATCTGTGCGGAAGTTGCTCACGAAAGTTAATTGCCGCCTACTACTATGTGAAGCAGGCGCAGGCCGCCAACGAACTGTtgataaaacaaattcatCGTAAGGGCGACAATGAGAAGGCGGTATTCGTTACAGATTGTCTGCAGGAGCTGCCCATGGAGCTGTGTATCGAGGAGCAGGTGGAGGTCAAATTGGAAACTGAGGAAGAGGAAACTGACAATGATATAACGTGCACAGAGCTACCAGAGCTGAGTACAGTACAGGAAACAAATGAAACAGACACTAGACTGGATAGTTGCATTAAAAAGTCGGATGATCCATTAACCATGTTGGATGCCGTCAAACAGGAAATGGAGTGCGCTGCACAAGCAGCTCACGCGCAATCGGAGTCTGAAAATGAAGATGATGAGTCGCTGGATGAtttgccgctgcagcagcgcgtaCACAAGTGGCTGGAGAGGGATACACAGGCTACGTTAAGATGGAAGCAGTACAAGTGCAATGAGTGCCCCAAGAGTTTCAAGCGTGTCGAATATCTAAAGCTGCATGCAGCACGTGCACACAGCTCCAAGGGCGATTGGTACTCCTGTTCGTTCTGCATACGCAAGTTCAGTCGTCGCGACACATTAAAGGCACACTTGAAAGTGCATCGTGATTCCAAACGTTCGGCCAATCTATGCGAAAGCAAAAAGGCCAAGGATATTGATGTTAATCTTTGCAAGCCGCAGGGCTATAAGCTTATCGAGTGCATGATCTGCCAGAgtcaatataataaaatagccGAGCTGCGTTGTCATCTTGAACAGCATCCGGATTTGGAGCGCAGCATGCGGACAGATATGCAGCTCAGTGAGGTCGCAGAGCTTCTCTATCCCGATGTTAAGGATGTAACAGAGCAAGTGCTAACCATGTACATACACCGCGACTTGGCAGCGTGCAACTATCAGCGCTTCTATTCCATAACGAATCAGTCCGGGTATGAAATGGATTTGGACAGCAGCGAAACGGAAAGTGAAACCGAGCTGGATCTGGATGATTATGCCAAGCATAGGCGTTGTGGCGCCGCAGTCAAAACCAAATACAGCTGTGAGTTGTGCCCACAACGATATGTGCGCAAATATCAATTGTATGAGCATCAGCGGCAAGCGCACGCTTGGCTGGAAGCGCCTCATGTCTGTGGACGCTGTGATGCACGATTTGTAAGCCTGCAATTGCTGAAGCATCACAATGAGACGCAATGCAAGAACGCACAGAAACGTTTCCTATGCCACAAGTGTCCGCTGCGTTTTCGCTGGCGTCACAATCTAAAAGCGCATACGAGGGAGCATCGCATAACCAATGAAACATTTGAATGCACCGACTGCAAACGTGTCTATGACAAGAAGAAATCCCTCACCGTGCATTTGCTTAGCGTTCATGGCGATGAATCCAAATTGATACCCTGCCAATGGTGTAGTCGCAAATTTTATCGTCGTGACTATCTGGTGAAGCATTTAAAACGACATGGCATACGCGAGCAGGATATACCGCTCGCCGAGACGCTTATTGCAGCCACTTCGAAAGCAAATGGCTGCAAACGCATCACttgcaaaatttgtaatttacaatttgatcGCATTAGCGACCTGCGTGCCCACATTCAGCTGGAACTGAAAATGGCACTCTCGCTGCATCAAAGCTACGATTCACCACACAATTACTCCATTACCAATGAGTCTGGTTATGAGTTGCAGTTGGGCGACTCAGAAACCGAGGACGAATTGCAACTTCCAAACACAGGTGCTTCCGGTCAAGCCAACTCGCGACTCGTCTATGTTTGTGAGCTCTGCAAAGTGCAGTGTCGACGCAAATACGAGATGATTCAGCATCAGCGTGCCATGCATAGATTCGACAAGATGCCATACGAGTGCGATGTGTGCATCTTTAAGTGCGTCTCCAAGAGTATTATGGAACAGCATAGACAAGCGCAGTGTCACAGCGCCGAGAAGCAAcatgcatgcaacaaatgcagttacaaatttatgtgGCCCGAGAATCTGCAACAGCATCTACAGCTGCAGCATGGTGGCGTTGAAGCATCACCGATTTTAGCTAGTGAAACAGATGACGGCAGGCGATTATCTGGCAATGCGGCGCCACTAGCAACGCCAACTGATAGTGTACCTTTGCTGCAATGCCCGCACTGCGATCGCACCTACCAAATGAAGTCGCGTCTGAACAATCATATAAGGGATGTGCATATTAATGGCGATCGCAAACGCAAGGAAGCCATAAAAAAATTCCTATGCTCGCTTTGCGGTCGTGAAACGCAATCGGCGGCAACATTAGTTACGCATATGCGACGTCACACAGGAGAAAAGCCCTTTAAATGTGATCTATGTGAAATGGCATTTCCACGCCACTCAGAAATGACATCGCATCGTCGTATGCACACGGGAGAGAAGCCCTTCCACTGCACAGTTTGCGGCAAGGACTTTGCGCGTTCCGACAAGCTCAAGCGACACATGCTAACGCATAGCGGACTCAAGCCACACAAGTGTACATACTGTGACAAATCCTACAGACAGGCCAAGgatttgaaattgcatttgcaacagCACACCGGTGAATGCCCATTTACCTGTGGCACCTGCGGCGAGCGCTTTATTCAGGGCACTGCGCTGGAGAAGCATCGCATGATGCGGCGTCACTTTGATGAGGTTGACGAGCGAAACGCCACAATAGTAACTGCTTAA
Protein Sequence: MKLPVMCRTCDARETDKLYKLTTPTKKFPDKLLSDILTELTNIELDTRLAQQLPQNLCGSCSRKLIAAYYYVKQAQAANELLIKQIHRKGDNEKAVFVTDCLQELPMELCIEEQVEVKLETEEEETDNDITCTELPELSTVQETNETDTRLDSCIKKSDDPLTMLDAVKQEMECAAQAAHAQSESENEDDESLDDLPLQQRVHKWLERDTQATLRWKQYKCNECPKSFKRVEYLKLHAARAHSSKGDWYSCSFCIRKFSRRDTLKAHLKVHRDSKRSANLCESKKAKDIDVNLCKPQGYKLIECMICQSQYNKIAELRCHLEQHPDLERSMRTDMQLSEVAELLYPDVKDVTEQVLTMYIHRDLAACNYQRFYSITNQSGYEMDLDSSETESETELDLDDYAKHRRCGAAVKTKYSCELCPQRYVRKYQLYEHQRQAHAWLEAPHVCGRCDARFVSLQLLKHHNETQCKNAQKRFLCHKCPLRFRWRHNLKAHTREHRITNETFECTDCKRVYDKKKSLTVHLLSVHGDESKLIPCQWCSRKFYRRDYLVKHLKRHGIREQDIPLAETLIAATSKANGCKRITCKICNLQFDRISDLRAHIQLELKMALSLHQSYDSPHNYSITNESGYELQLGDSETEDELQLPNTGASGQANSRLVYVCELCKVQCRRKYEMIQHQRAMHRFDKMPYECDVCIFKCVSKSIMEQHRQAQCHSAEKQHACNKCSYKFMWPENLQQHLQLQHGGVEASPILASETDDGRRLSGNAAPLATPTDSVPLLQCPHCDRTYQMKSRLNNHIRDVHINGDRKRKEAIKKFLCSLCGRETQSAATLVTHMRRHTGEKPFKCDLCEMAFPRHSEMTSHRRMHTGEKPFHCTVCGKDFARSDKLKRHMLTHSGLKPHKCTYCDKSYRQAKDLKLHLQQHTGECPFTCGTCGERFIQGTALEKHRMMRRHFDEVDERNATIVTA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -