Basic Information

Insect: Drosophila busckii
Gene Symbol: -
Assembly: GCA_011750605.1
Location: NW:91587-97396[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 20 0.0015 0.089 12.8 0.4 1 23 207 229 207 229 0.95

2 20 0.00026 0.016 15.1 2.5 1 23 235 257 235 257 0.97

3 20 0.0085 0.51 10.4 1.1 2 23 287 308 286 308 0.95

4 20 0.085 5.1 7.2 1.9 1 23 384 407 384 407 0.94

5 20 1.5e-05 0.00091 19.0 0.2 2 23 493 514 492 514 0.97

6 20 5.1e-06 0.00031 20.5 3.5 1 23 522 544 522 544 0.99

7 20 0.027 1.6 8.8 2.6 1 23 687 710 687 710 0.97

8 20 0.014 0.84 9.7 0.8 2 22 718 738 718 738 0.95

9 20 0.0067 0.4 10.7 1.9 1 23 747 770 747 770 0.93

10 20 5.6e-06 0.00034 20.4 0.8 1 23 793 815 793 815 0.98

11 20 0.0047 0.28 11.2 4.5 1 23 822 844 822 844 0.99

12 20 0.013 0.77 9.8 0.0 2 22 871 891 870 891 0.93

13 20 0.0032 0.19 11.7 6.9 1 23 936 959 936 959 0.96

14 20 0.023 1.4 9.0 1.2 1 23 996 1019 996 1019 0.96

15 20 0.0033 0.2 11.7 3.6 1 23 1045 1068 1045 1068 0.97

16 20 8.8e-06 0.00053 19.8 0.1 2 23 1093 1114 1092 1114 0.95

17 20 4.4e-07 2.6e-05 23.9 0.7 1 23 1120 1142 1120 1142 0.99

18 20 2.5e-06 0.00015 21.5 2.0 1 23 1148 1170 1148 1170 0.97

19 20 3.8e-08 2.3e-06 27.3 2.4 1 23 1176 1198 1176 1198 0.99

20 20 0.0063 0.38 10.8 0.3 1 23 1204 1226 1204 1226 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	20	0.0015	0.089	12.8	0.4	1	23	207	229	207	229	0.95
2	20	0.00026	0.016	15.1	2.5	1	23	235	257	235	257	0.97
3	20	0.0085	0.51	10.4	1.1	2	23	287	308	286	308	0.95
4	20	0.085	5.1	7.2	1.9	1	23	384	407	384	407	0.94
5	20	1.5e-05	0.00091	19.0	0.2	2	23	493	514	492	514	0.97
6	20	5.1e-06	0.00031	20.5	3.5	1	23	522	544	522	544	0.99
7	20	0.027	1.6	8.8	2.6	1	23	687	710	687	710	0.97
8	20	0.014	0.84	9.7	0.8	2	22	718	738	718	738	0.95
9	20	0.0067	0.4	10.7	1.9	1	23	747	770	747	770	0.93
10	20	5.6e-06	0.00034	20.4	0.8	1	23	793	815	793	815	0.98
11	20	0.0047	0.28	11.2	4.5	1	23	822	844	822	844	0.99
12	20	0.013	0.77	9.8	0.0	2	22	871	891	870	891	0.93
13	20	0.0032	0.19	11.7	6.9	1	23	936	959	936	959	0.96
14	20	0.023	1.4	9.0	1.2	1	23	996	1019	996	1019	0.96
15	20	0.0033	0.2	11.7	3.6	1	23	1045	1068	1045	1068	0.97
16	20	8.8e-06	0.00053	19.8	0.1	2	23	1093	1114	1092	1114	0.95
17	20	4.4e-07	2.6e-05	23.9	0.7	1	23	1120	1142	1120	1142	0.99
18	20	2.5e-06	0.00015	21.5	2.0	1	23	1148	1170	1148	1170	0.97
19	20	3.8e-08	2.3e-06	27.3	2.4	1	23	1176	1198	1176	1198	0.99
20	20	0.0063	0.38	10.8	0.3	1	23	1204	1226	1204	1226	0.98

Sequence Information

Coding Sequence: atGTTACCGGCCAACTTATGTCTCGCATGTGGGAAACAAGATGACAACGTGCATCCGTTATCCagaagagcaacaaaatatacaagcaaatgttttaagGATATGCTGCTTGAATTAACCCAAATACAAACAGATCCACTTTTGGAGCAACTTGACGACAAGCTGCCCCAGGGTATATGCAGCGACTGTCTTTGCAAATTGGATGATTCATACAAATTTGTAAGTCGGGCGCGACAAGTGTATGATGAGCTACTTACCAAGCTACGTAATGGATTGCAAAAAGATTGTCTTGACGAAACTCTGATTGATATGGAAATTCATCACATTAAAAGAGAAACGGACGTTAATCCAAGTCACGCCTGTGGTGAGAATGCAACACATATCAATGATAGTAATGGTGAAGCGATTGCTGCATACAAGTGGCATGCAGAGATTGATATGGAGAGCACTTATGAAGATGTTAACAGGGAAGACTTCGACGGTAATCCAGCTAATGAAAAACAAAGCCTTCGGAAGCAActtaaagaaaatgaaaaaaccgcAGGTAATGTCACCAGGCAGGGACGTCAACGTTCAAAGCAGCAGACCAAAATGGAGTTCGGAACACTGGAGGGACGTCATGCCTGCGAGGTGTGTGGAAAAACCTTCTCGTGGCTCCGTGGAATGCAGCGTCACGCACGAATTCATCTCGAGGCGCCCTCTCACGTATGCGATACCTGCGGCAAGAGTTTTCTGCGTAAAGACATGTACACGTTGCATTTGCGTTCACACACAGATTCGAGATGTCAGGCACCTGATCTTGGCAATGAATGGCTCTTTGCCCAACGTCTGTACAGCTCTACTCCCCTCACATGTATTAAGTGCAAATTGTGCGGCTTGAAGTGTGACCGAATTAAACAGCTTCGAGTGCACTTGGCAGAGCATATTAGCCCAGAGACCCTGTGCAATCTTAGGTTAGACAGCGATCTTGTGAAAGAGCAATTTGGcctacaacacacacaagtaaaTATGACCGATATCAAAAGGCAGGTGTGTTCTGATATTGCTAAAGGTGACCAACTGGACAGGTATTGTGAGGTGGTTAATGCGCATGGCTATGAGATAAGTCTCAGCGATTCTGATGAAGAAGTAGAGGACCTGACAGCTCCATACCAATGTCTTAGCTGTAACACTTTCTATACGCGCAAGTTTATGATAATTCGTCATACTCTGGAGCAGCACCCCGAAAGTTGCCAACGATGTGACATTTGTCAAATTGGTTTTGTTTGCGATAAGCTACTGGATCAGCACAGGCGCACACAGTGCCACAGTCCCCTAAAGCGTTACAATTGTCGTGATTGTCCTGGCAAGTTTATTTGGAAGCAGAATTGCGATAGGCATGCTTGTATCCAGAATAAGTTGCAGTCAGACACAGTTGACGTTAAACCGCGCCATACTAGGCTGGGTAGAAAACGAAGCCCAACTTCCAGTAAGCTGCAGTGCCCTGAGTGCGACAAGGTCTTCATTTGGCCAAAGGATTTAACGCGTCACAAACGCATGCATCAGCCACAGACTTGTGCACAATATGAATGCACTCACTGTGAACGAAAATTCTATCGCAAGGATGGTCTCAAATCCCATTTGCGCGTGCACGGCGAGCATCTTGACACAGCTTTAGTATTAAGCACTTCGACCAGCGAGCAGCAAACGGCAACGCCAATAATGCTTCAGCAACTGAGCCAAGCCAATGGCTGCAAGTTGATTCAGTGCATGATTTGTTTCTCACGACACGCAAGAATCTCGGATCTACGGCATCATTTGTCCATCCATCAGTCTGGAGTTAAATTTGAGAACATCGAGAACATTGCTGACATCTCTCGTGCTCTATATCCAGAAATTAGCGTGCCTTTTGAAAAGTATCAGCTTATTCAACGAATCCAAAGTGATGTGACAAATGGCGTGGAGCTGGATAGATTTATATCCATTACGAATGAGATCGGCATTGAATTAAGCTTGGAAAGTAGTGAAACTGACTCTGACTTGGAAAGTGAAGTTGCAGCTGTTATTAAAGATCGGATATACAGTTGTGATCTTTGTCAGTTCAAGGTAGGGCGAAAACATCAACTTTACGCCCATCAGCTGAAACAACATGAGTGGTCACATGCCCCACGCAAGTGCGTCCTATGTCAGGCAAGATTTGTCAATAACCAGCTCCTGCAACACCATTATCGCTCGTTCTGTCGGAATGCGCAAAAGCCATTCTTCTGCCATAAGTGTCCGTTACGATTTCGTTGGCGTGATAATCTAAAGTTGCATATCGCATTAACACATCAGGAAGTAGCTGATAGTGGTGAACAGTCGCAGGATAAGCTTCCAATGAGTGCGACTGTTGACAGTTATGAGTGCGTTGAGTGCAAGCGCACCTTTAAAATCCAAAAGGATCTGACGCGGCACATGCTGATACATGCCCATGAATCAAGCAAGTATCGTTGCCGCTGGTGTGCACGCCGTTTTTATCACAAGCTAAATCTCTTGCAGCACCTTAAACGACATGGCATCAATGCTGCCCAACTGCCTTACGCCGAGGCATTGTTGAATGCCACATGTCAGCCACACGGACGTAAGTGTATCGAGTGCAAGGTTTGCGAGCAGAGTTTTGGCAGCATTGCTGCACTTCGACAGCATCTATTGACATCTGCGCCAGGCACACACCACGCAATCGACTCCATGCTTAACTACTCGATCACCAATCAGCTTGGCTATGAGCTGCAGCTCGAAGATTCTGAAACGGATGATGAGACTAATTCGCTCGGCACTTTGCGCCAGTACACCTGCAGCATTTGCCATCTGCGTTGCTCACGCAAGTATGAGTTGCATCAGCATCAACAAGCCATGCACCGATTGGAACGCATCAGTGATGGTTGCAATCTGTGTATCTACAAGAGCGTCTCCTTGGAGCTTATAAAATACCACCAACGTCTGTTGTGTGAAAATTTGGAAAAACAGTTCAAGTGCTTAAAGTGCGAATACAAGTTTATGTGGGAGTCGAATCTTTTGCGGCACTTGCAGCTACAGCATCCTAGCACTGACGACAATTCAAAGGATGCGCCAGCAAAATCCACCCAAAACGAATCAAAAGCCGAGTGTCAAATCTTTCAGTGCGGCCAGTGTACCCGTAAATACAACCGTAAGGATCGCTTGGCGGCGCACGTGAAGAAATGCCATGCACCTGGTGCATTATTTAACTcaactaaagctgcagcatcaTCTCAGAACACTAAGCATCAGAAAAGCTTTCTCTGCGCTTTCTGCGGGAAAGCAGTAAGTTCGTCCTCTAATCTTATTATACACATACGTCGTCACACCGGCGAAAAACCGTTCAAGTGCGACTTTTGTGATATGGCATTTCCGCGTTCCTCCGACCTCCAGGTTCATAGACGCACCCACACTGGTGAGCGGCCTCACATTTGCACTGTATGTCAAAAGGGATTCGCACGCTCTTACAAACTTCAGCAGCATATGCGTATCCACAGCGGTGAGCGTCCATATAAGTGCACCTATTGCGACAAAAGCTTCACACAATCCAATGATTTGACGCTACACATCAGACGCCATACGGGTGAACGCCCATATGAGTGCGATACCTGCGGTGATCGTTTCATTCAAGGAACTGCACTTAAAAATCATCGTATGCAGCATGGTCACAATCAGGTCGATAAATAG
Protein Sequence: MLPANLCLACGKQDDNVHPLSRRATKYTSKCFKDMLLELTQIQTDPLLEQLDDKLPQGICSDCLCKLDDSYKFVSRARQVYDELLTKLRNGLQKDCLDETLIDMEIHHIKRETDVNPSHACGENATHINDSNGEAIAAYKWHAEIDMESTYEDVNREDFDGNPANEKQSLRKQLKENEKTAGNVTRQGRQRSKQQTKMEFGTLEGRHACEVCGKTFSWLRGMQRHARIHLEAPSHVCDTCGKSFLRKDMYTLHLRSHTDSRCQAPDLGNEWLFAQRLYSSTPLTCIKCKLCGLKCDRIKQLRVHLAEHISPETLCNLRLDSDLVKEQFGLQHTQVNMTDIKRQVCSDIAKGDQLDRYCEVVNAHGYEISLSDSDEEVEDLTAPYQCLSCNTFYTRKFMIIRHTLEQHPESCQRCDICQIGFVCDKLLDQHRRTQCHSPLKRYNCRDCPGKFIWKQNCDRHACIQNKLQSDTVDVKPRHTRLGRKRSPTSSKLQCPECDKVFIWPKDLTRHKRMHQPQTCAQYECTHCERKFYRKDGLKSHLRVHGEHLDTALVLSTSTSEQQTATPIMLQQLSQANGCKLIQCMICFSRHARISDLRHHLSIHQSGVKFENIENIADISRALYPEISVPFEKYQLIQRIQSDVTNGVELDRFISITNEIGIELSLESSETDSDLESEVAAVIKDRIYSCDLCQFKVGRKHQLYAHQLKQHEWSHAPRKCVLCQARFVNNQLLQHHYRSFCRNAQKPFFCHKCPLRFRWRDNLKLHIALTHQEVADSGEQSQDKLPMSATVDSYECVECKRTFKIQKDLTRHMLIHAHESSKYRCRWCARRFYHKLNLLQHLKRHGINAAQLPYAEALLNATCQPHGRKCIECKVCEQSFGSIAALRQHLLTSAPGTHHAIDSMLNYSITNQLGYELQLEDSETDDETNSLGTLRQYTCSICHLRCSRKYELHQHQQAMHRLERISDGCNLCIYKSVSLELIKYHQRLLCENLEKQFKCLKCEYKFMWESNLLRHLQLQHPSTDDNSKDAPAKSTQNESKAECQIFQCGQCTRKYNRKDRLAAHVKKCHAPGALFNSTKAAASSQNTKHQKSFLCAFCGKAVSSSSNLIIHIRRHTGEKPFKCDFCDMAFPRSSDLQVHRRTHTGERPHICTVCQKGFARSYKLQQHMRIHSGERPYKCTYCDKSFTQSNDLTLHIRRHTGERPYECDTCGDRFIQGTALKNHRMQHGHNQVDK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -