Basic Information

Insect: Drosophila burlai
Gene Symbol: -
Assembly: GCA_008042655.1
Location: VNJT01019613.1:82-5460[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.0042 0.32 11.6 1.8 1 23 175 197 175 198 0.95

2 8 0.0026 0.2 12.3 0.2 1 23 203 226 203 226 0.98

3 8 0.00045 0.035 14.6 3.9 1 23 403 426 403 426 0.95

4 8 0.00015 0.011 16.2 2.1 1 23 434 456 434 456 0.98

5 8 1.4e-05 0.0011 19.4 0.7 1 23 463 486 463 486 0.96

6 8 1.8e-05 0.0014 19.1 1.4 1 23 492 514 492 514 0.96

7 8 2.7e-07 2e-05 24.8 1.7 1 23 519 541 519 541 0.99

8 8 0.18 13 6.5 3.8 1 23 546 568 546 568 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.0042	0.32	11.6	1.8	1	23	175	197	175	198	0.95
2	8	0.0026	0.2	12.3	0.2	1	23	203	226	203	226	0.98
3	8	0.00045	0.035	14.6	3.9	1	23	403	426	403	426	0.95
4	8	0.00015	0.011	16.2	2.1	1	23	434	456	434	456	0.98
5	8	1.4e-05	0.0011	19.4	0.7	1	23	463	486	463	486	0.96
6	8	1.8e-05	0.0014	19.1	1.4	1	23	492	514	492	514	0.96
7	8	2.7e-07	2e-05	24.8	1.7	1	23	519	541	519	541	0.99
8	8	0.18	13	6.5	3.8	1	23	546	568	546	568	0.97

Sequence Information

Coding Sequence: ATGCTGCAGGCGCAGGCGCATCCTCGGATCCAAAACCAAGTAGTGCAGCAGCCCACCGTACAGATGATGCAGCAGATCCAACCGCAAGGCTACTCACAGCTGCAAATGCAATCCTCCTCCCACAACGACACCACGACGACAGTCACCTACGAGCAGATCTATCAGCAGCACATTGTCCAGCAGACGGTTCAAAAGTCCTCCAATAAGGTGCAGCTCATCTCGCTGCCCTCGTGCGCGGGAGAAACTAGGCAATGGCAGCCGcaacaccaccagcaccagcaccaacaccaacaccagcaTCAGCAAGTGCAGTGGTCATCGGTGGGCGGGCTGGAGTCTATCAAGAATTCACCCATCGAGACAACTTACTACATAAGTGCCAGCGATCTGTATCCGCAGCAGACAACGGAGACTTATACCATGCTGCAGCCGGCTTCTATGGAGGCCAATAACGGTCCGAGGTTCTCCAACAGCCTGGAGTACAGCCGTCACATCATTGAACTGCATCCCGCCGTAGCACCATTCAATTGTCCGCATTGCCCGCTGGCGTTTGCCGGCAGAAGTAAGCGGTCGCAGCACATCCTCAGCCACCACGTGGTCCAGCAGTATCAGTGCGGGCAGTGCTCGCAGGTGTTTCCCGCTCAAAAGGCCTTGGACCTGCACATCCAACGTTTCCACATGCCTTCAAAGGCCGTTGACAGCGGTGTCCcagcagcagcagcaatggaaGTCCAGGCGAGCACAACTACAACGCCGCGAAAGATTCTTTGCTGTCCCGACTGCGAAGATTGCACTGCAGGCGGCCACAGCCATGGCAGCTCTGCAGGATTCGAGGAACTCCCCTCGCTGCAGTCTCCTCCTCCAACGGTCCTCACCCCGCCCTCGACCATTGTTTCGGCTCCCTCGCCCCAGCCCATGATCGTTGCGTCGCAGCACATAACGCTGCCGTCGCCCGAACAATCCGAGCCAGATTCCACGACCACGTTACGCCAGTACCGTAAGCGAGGCGTCATTGTGGGGGGACCCCAGGGACCGCTGCATTGCATGGCCACACCTGTGGCATCGCCCTCGCCGTCCTCGTCGCCATCATCCTCCACCTTCGACCATGTGGTACCACCAGCGTCACCAGCTACGCCCGCTTCGCCGGCTCCGCCTCAGTCACCCGCCGCACCGCCGGCGGTGAGCAGCGAACTGCGAACAAACCATCATCAATGCTCCTACTGCGAGGAGCGCTTCACCAACGAGATTGCGCTTAAGAAGCATCACCAGCTGACCCACGGATCCCAGACCACGATGCCGTTCGTGTGCACCATCTGCAAGCGAGGCTATCGCATGCGCACGGCTCTGCATCGGCACATGGAGTCGCATGATGTGGAGGGCAGGCCGTACGATTGCAACATCTGCCACGTGCGCTTTCCGCGTCCTTCGCAGCTAACGCTGCACAAGATTACCGTGCACCTGCTATCCAAACCGCACACCTGCGACGAGTGCGGCAAGCAATTCGGTACGGAGAGTGCATTGAAGACGCACGTTAAGTTTCACGGTGGGATCGGTTACCAGTGCGACGGATGCGATCGGTCGTTCGAATATCTCAAGGAATTGCGCAGACATCGTCGTACCCACAAAGAGCTGTTTTACAAATGTGAATTCTGTCCACGGTCGTTTCTTCACTTTAAGATTTTTCGTGCACACATGAACTCCCATTTGCCATTGGGGGTATTTCTCAACGAAGAGACCATCATAAAGACCGCCAGCAGCACAAACAACAATACAAACAGTAGTGCTAAGCTAGAAAAtccaccaacaccaacacccaTCGTGGAGACAGCACCAAtgagcagcaataacaacaacgtGTATAATGTCCAAAGCCCAGATGAATACCCAAATTCGGTGGAaagctgtgctgctgctgctgctactagTGTGGCTCTGGAAACGATAGCCCCAACGCCATAA
Protein Sequence: MLQAQAHPRIQNQVVQQPTVQMMQQIQPQGYSQLQMQSSSHNDTTTTVTYEQIYQQHIVQQTVQKSSNKVQLISLPSCAGETRQWQPQHHQHQHQHQHQHQQVQWSSVGGLESIKNSPIETTYYISASDLYPQQTTETYTMLQPASMEANNGPRFSNSLEYSRHIIELHPAVAPFNCPHCPLAFAGRSKRSQHILSHHVVQQYQCGQCSQVFPAQKALDLHIQRFHMPSKAVDSGVPAAAAMEVQASTTTTPRKILCCPDCEDCTAGGHSHGSSAGFEELPSLQSPPPTVLTPPSTIVSAPSPQPMIVASQHITLPSPEQSEPDSTTTLRQYRKRGVIVGGPQGPLHCMATPVASPSPSSSPSSSTFDHVVPPASPATPASPAPPQSPAAPPAVSSELRTNHHQCSYCEERFTNEIALKKHHQLTHGSQTTMPFVCTICKRGYRMRTALHRHMESHDVEGRPYDCNICHVRFPRPSQLTLHKITVHLLSKPHTCDECGKQFGTESALKTHVKFHGGIGYQCDGCDRSFEYLKELRRHRRTHKELFYKCEFCPRSFLHFKIFRAHMNSHLPLGVFLNEETIIKTASSTNNNTNSSAKLENPPTPTPIVETAPMSSNNNNVYNVQSPDEYPNSVESCAAAAATSVALETIAPTP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -