Basic Information

Insect: Drosophila burlai
Gene Symbol: GFI1
Assembly: GCA_008042655.1
Location: VNJT01013066.1:27115-44741[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.00017 0.013 16.0 3.6 1 23 469 492 469 493 0.96

2 6 0.00026 0.02 15.4 0.5 1 23 498 520 498 520 0.97

3 6 3e-07 2.3e-05 24.6 1.9 1 23 526 548 526 548 0.98

4 6 1e-05 0.0008 19.8 4.2 1 23 554 576 554 576 0.97

5 6 1.8e-07 1.4e-05 25.3 2.5 1 23 582 604 582 604 0.98

6 6 3.7e-05 0.0029 18.1 5.0 1 23 610 633 610 633 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.00017	0.013	16.0	3.6	1	23	469	492	469	493	0.96
2	6	0.00026	0.02	15.4	0.5	1	23	498	520	498	520	0.97
3	6	3e-07	2.3e-05	24.6	1.9	1	23	526	548	526	548	0.98
4	6	1e-05	0.0008	19.8	4.2	1	23	554	576	554	576	0.97
5	6	1.8e-07	1.4e-05	25.3	2.5	1	23	582	604	582	604	0.98
6	6	3.7e-05	0.0029	18.1	5.0	1	23	610	633	610	633	0.97

Sequence Information

Coding Sequence: ATGGACGTAGCCAAAATGCAAGCCGCTTCCGGCCAGCATCTGCTGCATCCCGCTGCGCCACCCGCCCACCAACACCACCTGCCGCTCGACTACAGCTTGGGCAATTTCAAGCCAGCCATTGCGGCCGACTTTCCCGGACCCTTCCTCGccagccaacagcagcagtccTCCACGGCCTCGAATTCCGCCTCGTCCGGTTCCGGCTCCGGTGCCGCATCCGCCTCCACTTCCGCCTCGCTGCAGGTGCGCGATCTCAGCGCCCTGACGGCCATGGCCACGATACCCTCGCCCACGCAACTCCTCCAGCAGCGCATCCAAATCTCTGCGGACGCGGCCCTGGGtcaccaccagcaacagcaccagcaccaggcGTCCCAGAATCCGCCGCAGGCACCGATGCCGACGGCCCCAACATCGCCGCACGAGTACGCGCCCATCTCCGCGTTCAAAGCGGTAACGCCCAAGAAGCGCACCTCCGACGATGCCGCCCTGGCATTTAGCATTAGCAGACTGGTCAAGACTGAACTCCTAACAGCCGCCGTTGGCCTGAAGCCGCTGACTCCGCTGGAGGATAACAACAACTCCATCTCCATGCTGAGCAAAAACcagatgcagcagcaccaactgcatcagcagctccagcagccaCGTTCCAAGCCGGCCTTCATCAGCGCCAGCGAAAAGTTGAGGCGACAGTCGCGATCCCGTTCCCGTTCGCGGTCCCGGAGTCGCTGCTCCTCGCAGATCGACATGGAGGACGCGGAGTCGCACCATTCGCACCGCTCGCTACATTCTCGCTCGcgatcccgctcccgctcccactCCCGTTCCCGCTCGCACTCGAGCAGCTCGTCGGTGGAACTGGAGGTCGACTCGCCGCCAGGCAGTCCGCGGATCAGTTCACCCAGcaccgcctccgcctcggAGCTGCTTATAACGGCCAATGGGGGCGCCAGGAGCATTGGGTCCAAGAAGTCCGATCTCTTCTCCGTGTCCGCTCTGCTGCGAAGGGATGAGCCACCCCAGAGACGCACGCCGCGCAGCCCGCCGCTGGGTCACCTGGCCGCCGGCGGCCTGCCCATGCCCTTTAATCCGCTGGAGGCAATGCGCCAGGGCTATCCGCCCAACTACGACGCGGCCATCTATCATCCGGACTCGCAGGAAAATCTCTTCCGCCTGCGGAGTCTAATGGTGCCACTGCAATCCGCCGGACAGAACAACTccacagcggcagcggctgcggcggcagctgctgcggccgcCGTCGGCGTGGGCGTCGGTGTGGGTGTCGGAGTGGGCGTGCCACCCAACGGCGGGCACCTGGGACTGCCGCACTCGCCGCACCTGCACCACTTCCACCACATGGCCGCCAAGTGGCCGGGCCTGCACCAATTCAGCGACCTGTACTCGTGCATGAAGTGCGAGAAGATGTTCTCCACGCCGCACGGCCTCGAGGTCCACTCCCGCCGGACGCACCACGGCAAGAAGCCCTATGCCTGCGAGCTCTGCAACAAGACCTTCGGGCACGAGGTCAGCCTCAGCCAACACAGAGCGGTGCACAACGTGGAGAAGGTGTTCGAGTGCAAGCAGTGCGGAAAGCGCTTCAAGCGCTCCAGCACGCTGTCGACGCACCTGCTCATTCACAGCGACACGCGGCCTTATCCCTGCAACTACTGCGGCAAGCGGTTCCATCAAAAGAGCGACATGAAAAAGCACACCTACATCCACACAGGTGAGAAACCGCACAAGTGCCAGGTATGCGGCAAGGCCTTCAGCCAGAGCTCCAACCTGATAACGCACTCTCGCAAGCACACCGGCTACAAGCCCTTCTCCTGCAAGCTCTGCCACAAGTCCTTCCAGCGCAAGGTGGACCTGCGGCGCCACAAGGAGACCCAGCACACGGACCTGCGCGTCCACCTTGGCAAGGTGGACTTCAtgtcggcagcagcagcggcggcggcctcTGCCGAGTTGagtgcagcggcggcggcagcgggtGGCGGAGTGTCCCCGGCAAACCAGGGTGCACCGCCTCCGAACGGAGGACCCGCCCCGATGGGCGGCGGGCTCAACTGTCAGAAGGTGTCGCTGCTGGTataa
Protein Sequence: MDVAKMQAASGQHLLHPAAPPAHQHHLPLDYSLGNFKPAIAADFPGPFLASQQQQSSTASNSASSGSGSGAASASTSASLQVRDLSALTAMATIPSPTQLLQQRIQISADAALGHHQQQHQHQASQNPPQAPMPTAPTSPHEYAPISAFKAVTPKKRTSDDAALAFSISRLVKTELLTAAVGLKPLTPLEDNNNSISMLSKNQMQQHQLHQQLQQPRSKPAFISASEKLRRQSRSRSRSRSRSRCSSQIDMEDAESHHSHRSLHSRSRSRSRSHSRSRSHSSSSSVELEVDSPPGSPRISSPSTASASELLITANGGARSIGSKKSDLFSVSALLRRDEPPQRRTPRSPPLGHLAAGGLPMPFNPLEAMRQGYPPNYDAAIYHPDSQENLFRLRSLMVPLQSAGQNNSTAAAAAAAAAAAAVGVGVGVGVGVGVPPNGGHLGLPHSPHLHHFHHMAAKWPGLHQFSDLYSCMKCEKMFSTPHGLEVHSRRTHHGKKPYACELCNKTFGHEVSLSQHRAVHNVEKVFECKQCGKRFKRSSTLSTHLLIHSDTRPYPCNYCGKRFHQKSDMKKHTYIHTGEKPHKCQVCGKAFSQSSNLITHSRKHTGYKPFSCKLCHKSFQRKVDLRRHKETQHTDLRVHLGKVDFMSAAAAAAASAELSAAAAAAGGGVSPANQGAPPPNGGPAPMGGGLNCQKVSLLV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00591916;
90% Identity: iTF_00606546;
80% Identity: -