Basic Information

Insect: Drosophila burlai
Gene Symbol: Hivep2
Assembly: GCA_008042655.1
Location: VNJT01015631.1:62840-72598[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.00024 0.018 15.5 0.2 1 23 208 230 208 230 0.98

2 8 0.00024 0.018 15.5 2.9 1 21 236 256 236 260 0.89

3 8 0.0037 0.28 11.8 0.1 1 19 546 564 546 567 0.93

4 8 2.1e-06 0.00016 22.0 2.0 1 23 1274 1296 1274 1296 0.99

5 8 9e-06 0.00069 20.0 5.3 1 23 1302 1326 1302 1326 0.92

6 8 0.00011 0.0082 16.6 2.6 2 23 1797 1818 1797 1818 0.97

7 8 0.00062 0.047 14.2 1.2 1 23 1824 1848 1824 1848 0.91

8 8 0.002 0.15 12.6 2.7 1 23 1869 1893 1869 1893 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.00024	0.018	15.5	0.2	1	23	208	230	208	230	0.98
2	8	0.00024	0.018	15.5	2.9	1	21	236	256	236	260	0.89
3	8	0.0037	0.28	11.8	0.1	1	19	546	564	546	567	0.93
4	8	2.1e-06	0.00016	22.0	2.0	1	23	1274	1296	1274	1296	0.99
5	8	9e-06	0.00069	20.0	5.3	1	23	1302	1326	1302	1326	0.92
6	8	0.00011	0.0082	16.6	2.6	2	23	1797	1818	1797	1818	0.97
7	8	0.00062	0.047	14.2	1.2	1	23	1824	1848	1824	1848	0.91
8	8	0.002	0.15	12.6	2.7	1	23	1869	1893	1869	1893	0.92

Sequence Information

Coding Sequence: GCCATTGCCACAAATAACCATCATAGCAACACGCCCGCCACGCCCGATGGACCCGCCCTCGTCGGAGATTGCTCTAGCAATATTTCGAGGTATCTTCACAAGAAGTTCAAGCGTCTGGCCAGCACCACCGATGTCGAGAGCGGGAATGCCACGGCAAATGGTGGCCATTTGACCTCCGCTGATGCTGCCGGTGGTATGCGTACCACATCGCTGTCCTCAAATAGCTCACTGTCACCTCCCCCGATGGTCGCCAATGGTCACCATTTGACCCAACAGCtagcccagcagcagcctcagcagcAAAATAGACCGACCACCACAACCACACATGAATTCAGTGCCAATTTTGTAAATAGCAATCATGTCAATGCCATTGGTCATGAGGAGAGCAATAGCCACAAAGCGGCGTTGAATGCGAGAACGCGAACGCCGCTGACTaacagcggcagtggcagcaactATGCAGCGAATGCCACACTGTCGCCGGCCAACTTTGCCCAGCACCAGCAACTGACGCAGCCAACAACAGCGGGAGGAGCTGGGATCgcaggcggaggcggcgggaTACCAGGCGGTGGAGGCGGTGGAGCAGCACTAGCAGCCGGCGAGAAAGCCGGACGCTATGTGTGCCCATATTGCAATCTGATCTGTGCCAAACCCtcggtgctggagaagcatATACGCGCCCACACCAACGAACGGCCATATCCCTGTGACACCTGCGGAATCGCCTTCAAGACGAAGAGCAACCTGTACAAGCACTGTCGCTCCCGGTCGCATGCGGCCAGAGCCAGAGGCTTGGAAGTGCCGGCGGATGCCGACGATGGGTTGTCGGATCAGGATGCTGAGTTGAGCAACAGTAGCTCGGAATTGCCAAGTCGCGCTGGTTCGCCATACGATGAGCCCATGAGTTCACCCACACCCTCACCTTCCACGCTGTCGGCGGCCAAGAGCGCCTACAttcagcagccgccgccactgccgcaGCATATGCAACAATTGCCGCTGGGCTCGCCAGCTGCTGGCACCTTGCCGCCCACAACGGCGGACAATCTGCATTCGGCCACTGCCCAGCATCGTCAGTCGATTGACTACAAGCCATATAAGCCCAAGTTCCATAATGCCTCCTTTCAGGTTTCCAATGTGACACCGGcccctgccacgcccacgccagCTGCGGCGGCCAATCTCAGCACTTTTGCCAGCTCCAGCGGCAGCATGCAAGTGAATGTGGCCAAGGTGCAGGAGCACATTTCCAAGTTGATCTCACAGAACGAGGCTATAGTGGAGAACAAGGAGATTTTGCTGCAGAAGAAGTATCCCAAGCAGCTGAATCGTTCCCGCAGCTTCAACAATGCCAATAGCACGAATCATGCGGCCAATGCGGCGGCGGCTTTGCATGCGAGCAGCCAAAATCTGAGTGCACAGATGCCGGAGCGAGAGACGAAGCCAAAGCCCGCCGTGATTACAGTGCCCGTAAGCACTGTGCCGGCAACGCCCTCTAGTTCAGCCACGCCATCGGGCAGCTCGAAGGCGACACCACCGACTggacaaattaataattcaatcaTCAAGAATCTGCTGTTGAATGCACGTGGCCTGGCGGTCCCCATTGGCGAGGGCGACGATGCCGTTTACTCGTGCCCCATCTGTGCCACCGAATTCCGCAGTGCGGACGATCTGAAGCTGCACAACAGCACCTACTGCCAGGACGCGAGTTCCAGTGCACCCATGAGTCCCGCCTCGTCGCCCTTCCGCTCCAATTCGTTGTCGTTAAGTCTGCCGGAGCTGAAGTGTCACATGGCCAACTCGAAGAATCCGCTGTCGCTGGCCAAGTTGGCCTGGTCGCAGCTGAGGACAAAGCGAAGCAGTTTGGTGGCAAGTCGCCTGAATGCAGCTCAGACGCCAGCGAGAACGTCAACTGTGACAGCTTCCACTGGAagtgctcctgctgctgctgctcctgctcctgtcccGGCACCGGCACCGCTTCCTTCGAGCCTTGCTACCGCGCCACAGCTGCCCCTTGAGGGACTCCGCTTTGTGGATGCACCACTGCCATCGCCTGGTCCCCTGCTTGGCAAGACGCCCCTGGTGGACTATGCACAGCAGAATGCGCCGCGCAAGGCTCAGGACTCGGTGGTGATTACGAAAATGCACGAAGATCGCCAGTTTGCCAGCTTGGATATCGAAGCTCCGCACGCCAAGCGTGTAAAGAGCAGTGATTTGGCTGCATcggcttcctcctcctcgcaaGGCTTCTCCTTTCCCTTTAATAACAACAACCTGCCTGAGCCGCCCGTCAAGGAGGAGCGCCTGCGCAGGTTTACATCGTCGGGGGGAACAATGATTCCCATCTCGGAATGCCCCGACTTGGAGAACAGTCCCAAGATGATACGTACACCGTTGCTGTCCGGTGGAAGCTTCCAGGAGGTTTCGGCCAAGGTAAACGATGCCCCGGGATCCAGCAAGGAGCGCAAACGCTTGGCCCTCATCGGTGGCAGTGGACTGCTCGGCGTCAGCTCCGGTCCGCAGCACTTTCAGTTTCCGCCCATCAACTCGATAACTGCCTTCAATCCGCTGACATTGCCACCAATGAGCGACAAGTCCACTCCCGTGACGCCCATTCCCTATGTGCCCGGCATTCCGGGGCCAGGAAGTCTGACGCCGCagatgccgctgctgccaccgccgccacagcagctgcagttgccTTCGGTTCCCTCGGGCCGCGGACGTAGCCCGAATCGCAAGCAGCCCAGCCCGCTCCTAATGggagccgctgctgctggtgaacTGAAGGCTCTCTCGCCCTTTGGCGGAGTCCAGAATTTGCCCAGCGAATTCAGTCGCCAGCCCCCAACTCCCGCCCAGCGGCAGGCGTTGCAGTGGAACAGCAACAAGGAGTCGACGACGACGCCCAAGAAGGCGCCATTCAATTTTCTGCGAATGGCGGATAATGTCaaggccaccaccaccaccaccacggaACCGGAAGTGCGACACTTTAATCTGGACAATGTGATTGCTGGCAAACAGGCGGCAGCAGAGGCGTCGCCACTGACACCACTCCATGTGGAGACACCCAATGGGAGTGGTGCCACGGAGGAGGCAGGAAGTCAGAGTTCCTCCGCCAAATCAAAGTTCCTGCGACCCACTAGCCTGCCCCTGAAGCCGGGAACATTTACGCCAAAGCGTCATCATGGGATTACACCGACGGCCAACACCCTGCCGCTAATCTCGCCGGAGACGCCGCGTCCCTCCAAGTCCTGCGTCCAACTCTACCTCAACGGCCATGCGTACACCTACCTGGGCCTCAAGTGCAGCACCAAGATGTTCTACTGCACCGTGAACTGTCCGCAGCCCTCGTATGTGGCGGGCATGCACAAGCTGTCGATGTACAGCGTGTGGCAGGTGTGCGAGGAGAACCAACCGCACCCGCTGGGCTTCAAGCTGAAGAAGGTGATGTCGCTGTACGACTCGCGGCAACGGATGCTGGGTAATGGCAGTTCCACCGCCATGGCTGGTTCGGGGAAGCTGAGCTACAATGTGGTCGCCTCGCAGCAGACAGTGTGCTCGATATCCACGCTGGCCAGTGCCAGTGGCAGTGCCTTCTATCAGAATCAGCTGAAAGCATCGCCGGCAGTCACTGTGTCGGTGCTGAGCGAGGCCAATGTGGCGGCCAAGGcgaacgaggaggaggaggcggcggcggcgcaggCCAAGAAGCTGGAGACCAGTCCCTCGGGACAGCCGCTGGTTGGTGGCTACGAGTCGCACGAGGATTACACCTACATACGGGGCCGGGGACGTGGCAGATATGTGTGCTCCGAGTGCGGAATCCGCTGCAAGAAGCCGTCGATGCTGAAGAAGCACATTCGCACCCACACGGATGTGAGGCCGTTCACCTGCAGTCACTGCAACTTTAGCTTCAAAACCAAGGGAAACCTCACCAAGCACATGCAGTCCAAGACGCACTTCAAGAAGTGCATCGAACTGGGCATTAATCCGGGACCCATGCCTGCCGATGGCGAGTTCCTGGATGTGGACATGGACTTTGATCAGCAGTCGTCGACCTCGGCAGGAGGACGCACATCCTCGATGGCGGGAGAGTCGGATTCGGATGACTACAGCGACAATGAATCGGAGAGTAGTGACACTGACGAGTCCAAGTCCAGGTTAAAAGAGCACGAGGCAGCCAGGTGCCTGCTGTCGCTATCGATGACGCCGCCCATTCCACAGAGTGTGTCGCCATATCCTCAACTGCTCCAGGACACACCTCTGCCCGCTGCCAGTCCCGCGAACAGCATCGGTTCCTCGGGCTCTTTGCCCAAGCGTTTGGTTTGCTCATTTACCTCGCCAAAGCCACCGTTTGACTATCAGAAGCAGGAACAGTATTACTCCAATCCCGAAGAGTCCAAGCCGAAGCGCAGCGTTGCCAGCGAGGAGAGCGCTCCCATGGATCTGACCAAGCCGCGTGGCTCCATGTCAGCCGCAGTCTCGCCATCGCCAGTGCCAGTTGCAGTGCcagtgccgccgccacctGTTCACGATTTGCCCAAGTCGCAGGCCCAGCAAATGCACGATGTGATCTTCGGCAGCGCCGGCAACGAAAGCGGCTTCATGAAGACCTTGATCTCAGTGTCGGACAAGGTGCGCATCTCGGCCGAAATGGAGGAGCAGGCCAAGCACGAGGCCGAGGGCGAGGATGTGCTGCTGCAAACGTACATCAAGGAGCAGGCGCTGCATCATGCCAAGCGGAAGCAGAGTCAGTTCAGTGGCAGCTATCTAATCAACACTTTGTTCTCCACGGCGAACACGACGTCTGCGGTGATGAGTAGCAGTAGCAACCTGTTGACCACCAGCAGCCGGCCCATTATGACCATTAATGAGGTGCCCAGCATCGAAGTTCATGAGGTCAAGACGCCAGAGTCTGTGGACTTGCCAGCCTTACCGCCTGCAGTTGCTCcaccaactccaactccaacacGTGCCCTCACTCCCACGCCCACGCCTACGCCCATTCCCGTGAAGCTGGTCCAGGAAGAGAGCGAAGAGTCGGATCAGGAGAAGCCCCTGGTAGAGCCACATAATGCCAATCTGCCGGCTGCAGTGCAGCAGAAGGATGCCAATGATTTTAGCGGAGTCCTTGGAGCCGCCACAGTGGccacatcaacaacaacacctGCTCCCGTGGCTCCCGTATCCACCTCGAACTCAAACACGAACACAAACACCACTCAGCCCACGCAGCGAACTGTGATTGTGGGCGAGGATGGCTTCAAGAACTCCACGCCCACCAGCAAGAGCAGTGATCTCCAACAGCAGCATGTATCCTATGGCCGAGCAGTGCCTGTCCCAGCTCCCATTGCCAGCGATGTGCGGCCCACCTGCTCCATCTGCGCCAAGACGTTCCAGCGCCAGCATCAGCTAACCCTGCACATGAACATCCACTACATGGAGCGCAAGTTCAAGTGCGAGCCATGCAGCATCTCGTTCCGCACGCAGGGACACCTGCAGAAGCACGAACGTTCCGAGGCGCACAAAAACAAGGTGATGATGACGTCGACATTCGGCGTCCCAACCACCTCGAATCCACGACCCTTCGAGTGCACCGACTGCAAGATCGCCTTCCGCATCCACGGCCACCTGGCCAAGCATCTGCGCTCAAAGACGCATGTCCAGAAGCTGGAGTGTCTGCAGAAATTGCCTTTCGGCACCTACGCGGAGATCGAACGCGCTGGCATCAGCCTCACCGAGATCGATACCAGTGACTGCGAGAACTCGCTGATATCTCTCAAGTTGCTGGCCCAAAAGCTGCTGGAGAAGGATCCCAATAAGCTGAGCGGCTACACCACACCGTCCGGCATGATGCAGCTGGCCCAGGATCCGGCGAATCCTGCCTCGCAGGATAGCGCCTCCGAAGATGGTTTCAGTGCCGCCGTGGCCATAGCCTCGGCCATTGCTTCGCTGGACAATGACAGTGCCGGCAATACACCGAAACGGGCCAGCTCGATGTCCGAAGATGAATCGGTGGCCAATGGCCTGAATCACAACCTTAAGCGCCGTTTGCCCGGCAGTTTCAGCAGCACGGGTGAGGAGAGCGATAATCCCAACGAGGGCAACGAGAAACGTGCTCGTTCCAGCCAGGATCTACCACCAGTTGCTCTTCCCGTTGCTGCCTcgccggcagcggcggcggcggcggccagcaACTGA
Protein Sequence: AIATNNHHSNTPATPDGPALVGDCSSNISRYLHKKFKRLASTTDVESGNATANGGHLTSADAAGGMRTTSLSSNSSLSPPPMVANGHHLTQQLAQQQPQQQNRPTTTTTHEFSANFVNSNHVNAIGHEESNSHKAALNARTRTPLTNSGSGSNYAANATLSPANFAQHQQLTQPTTAGGAGIAGGGGGIPGGGGGGAALAAGEKAGRYVCPYCNLICAKPSVLEKHIRAHTNERPYPCDTCGIAFKTKSNLYKHCRSRSHAARARGLEVPADADDGLSDQDAELSNSSSELPSRAGSPYDEPMSSPTPSPSTLSAAKSAYIQQPPPLPQHMQQLPLGSPAAGTLPPTTADNLHSATAQHRQSIDYKPYKPKFHNASFQVSNVTPAPATPTPAAAANLSTFASSSGSMQVNVAKVQEHISKLISQNEAIVENKEILLQKKYPKQLNRSRSFNNANSTNHAANAAAALHASSQNLSAQMPERETKPKPAVITVPVSTVPATPSSSATPSGSSKATPPTGQINNSIIKNLLLNARGLAVPIGEGDDAVYSCPICATEFRSADDLKLHNSTYCQDASSSAPMSPASSPFRSNSLSLSLPELKCHMANSKNPLSLAKLAWSQLRTKRSSLVASRLNAAQTPARTSTVTASTGSAPAAAAPAPVPAPAPLPSSLATAPQLPLEGLRFVDAPLPSPGPLLGKTPLVDYAQQNAPRKAQDSVVITKMHEDRQFASLDIEAPHAKRVKSSDLAASASSSSQGFSFPFNNNNLPEPPVKEERLRRFTSSGGTMIPISECPDLENSPKMIRTPLLSGGSFQEVSAKVNDAPGSSKERKRLALIGGSGLLGVSSGPQHFQFPPINSITAFNPLTLPPMSDKSTPVTPIPYVPGIPGPGSLTPQMPLLPPPPQQLQLPSVPSGRGRSPNRKQPSPLLMGAAAAGELKALSPFGGVQNLPSEFSRQPPTPAQRQALQWNSNKESTTTPKKAPFNFLRMADNVKATTTTTTEPEVRHFNLDNVIAGKQAAAEASPLTPLHVETPNGSGATEEAGSQSSSAKSKFLRPTSLPLKPGTFTPKRHHGITPTANTLPLISPETPRPSKSCVQLYLNGHAYTYLGLKCSTKMFYCTVNCPQPSYVAGMHKLSMYSVWQVCEENQPHPLGFKLKKVMSLYDSRQRMLGNGSSTAMAGSGKLSYNVVASQQTVCSISTLASASGSAFYQNQLKASPAVTVSVLSEANVAAKANEEEEAAAAQAKKLETSPSGQPLVGGYESHEDYTYIRGRGRGRYVCSECGIRCKKPSMLKKHIRTHTDVRPFTCSHCNFSFKTKGNLTKHMQSKTHFKKCIELGINPGPMPADGEFLDVDMDFDQQSSTSAGGRTSSMAGESDSDDYSDNESESSDTDESKSRLKEHEAARCLLSLSMTPPIPQSVSPYPQLLQDTPLPAASPANSIGSSGSLPKRLVCSFTSPKPPFDYQKQEQYYSNPEESKPKRSVASEESAPMDLTKPRGSMSAAVSPSPVPVAVPVPPPPVHDLPKSQAQQMHDVIFGSAGNESGFMKTLISVSDKVRISAEMEEQAKHEAEGEDVLLQTYIKEQALHHAKRKQSQFSGSYLINTLFSTANTTSAVMSSSSNLLTTSSRPIMTINEVPSIEVHEVKTPESVDLPALPPAVAPPTPTPTRALTPTPTPTPIPVKLVQEESEESDQEKPLVEPHNANLPAAVQQKDANDFSGVLGAATVATSTTTPAPVAPVSTSNSNTNTNTTQPTQRTVIVGEDGFKNSTPTSKSSDLQQQHVSYGRAVPVPAPIASDVRPTCSICAKTFQRQHQLTLHMNIHYMERKFKCEPCSISFRTQGHLQKHERSEAHKNKVMMTSTFGVPTTSNPRPFECTDCKIAFRIHGHLAKHLRSKTHVQKLECLQKLPFGTYAEIERAGISLTEIDTSDCENSLISLKLLAQKLLEKDPNKLSGYTTPSGMMQLAQDPANPASQDSASEDGFSAAVAIASAIASLDNDSAGNTPKRASSMSEDESVANGLNHNLKRRLPGSFSSTGEESDNPNEGNEKRARSSQDLPPVALPVAASPAAAAAAASN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00617803;
90% Identity: -
80% Identity: -