Basic Information

Insect: Drosophila burlai
Gene Symbol: zfh1
Assembly: GCA_008042655.1
Location: VNJT01001523.1:1784-17142[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0023 0.18 12.4 1.3 3 23 42 63 40 63 0.95

2 9 0.00055 0.042 14.4 0.1 1 23 189 211 189 211 0.97

3 9 7.9e-05 0.0061 17.0 0.6 2 23 225 246 224 246 0.97

4 9 4.2e-06 0.00032 21.0 6.3 1 23 255 277 255 277 0.99

5 9 0.00025 0.019 15.5 1.2 3 21 285 303 283 304 0.94

6 9 0.0058 0.44 11.2 0.7 2 21 501 520 500 521 0.92

7 9 1.1e-05 0.00086 19.7 0.5 1 23 843 865 843 865 0.94

8 9 4.2e-05 0.0032 17.9 7.4 1 23 871 893 871 893 0.98

9 9 0.0021 0.16 12.6 4.3 1 21 899 919 899 920 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0023	0.18	12.4	1.3	3	23	42	63	40	63	0.95
2	9	0.00055	0.042	14.4	0.1	1	23	189	211	189	211	0.97
3	9	7.9e-05	0.0061	17.0	0.6	2	23	225	246	224	246	0.97
4	9	4.2e-06	0.00032	21.0	6.3	1	23	255	277	255	277	0.99
5	9	0.00025	0.019	15.5	1.2	3	21	285	303	283	304	0.94
6	9	0.0058	0.44	11.2	0.7	2	21	501	520	500	521	0.92
7	9	1.1e-05	0.00086	19.7	0.5	1	23	843	865	843	865	0.94
8	9	4.2e-05	0.0032	17.9	7.4	1	23	871	893	871	893	0.98
9	9	0.0021	0.16	12.6	4.3	1	21	899	919	899	920	0.96

Sequence Information

Coding Sequence: CCCTCGCTGGCCTCCAGTCTGCTTCACCACAACCAGTCGCCGAAGCACAGCAATCCAGGCAATGTGGTGCAGGATGCCCAGATTGCACAGCCAGGACCGGCTGCAGATGCCTTCATGGTCAATTGCACCCAGTGCCACAAGCGCTTCATCGGGTTTCAGAGCCTTACCGAGCACATGGCCAGCGAGCATCCCCACGACAAGCTGAACTGTGGAGCTGCCCAGCCCGAGAGCGATGCCGAGGATGAGCAGAGTAATctcagtggcagcagcagtcggCGGTACATCAAGTCACCAGCTCAGGCCACTGGCAACACCtcaaacaacagcaacaacaacaacatcagtgTCCATCCCAGTAGCAACTCcagtaacaataacaacaacaacagcgagcTGACCAAAAaccagaacaacaacagcacaacCCCAAAGATGTCACCCATGTGCTCACCTGGTTCCATGCCACCGAGTGACTTATTCGCTCACCTGCCCCATGGAACGCCTCAGCTGCAATTGCAAGCCCATCCGGGCTCCACTACCGGAGATCGGGAGCTGGGCGGTGCCTATCCCTGCATGCAGTGCACGGCCGCCTTTGCCACACGGGAGCAGCTCGAGCAGCATCAGCTGCTGCACTCGCCCTGCGGCCAGCCAGCGGCGCAGAATGTCTCTCAGACCTGCCGAATCTGCCAAAAGGCGTTCGCGAATGTTTATCGCCTGCAGCGGCACATGATCAGCCATGATGAGAGTGCTTTGCTGCGAAAGTTCAAGTGCAAGGAGTGCGACAAGGCCTTCAAGTTCAAGCATCATCTCAAGGAACATGTCCGCATCCATTCCGGGGAAAAGCCCTTTGGCTGCGACAATTGCGGCAAGCGCTTCTCCCACTCGGGCAGCTTCTCCTCCCACATGACGTCCAAGAAGTGCATCAGCATGGGCCTCAAGTTGAACAACAATCGTGCTCTGCTCAAGCGATTGGAGAAGAGTCCCGGCTCCGGAGGCGCAGCTCGTCGCTCGCCCTCGGATCAGGGTCttaagcaggagcagcaatcGGGGCTGCCGGGATTGCCGAATCCGATGATCTACTTTGCCAGCGATGCTCAAGGGCAGGCGGGAAATACAGCTGCCACGCCCTTCCCACCTTTCCATCCCACAAACTACATGAATGCGGCTCTGTTTTCCTTTCCCAATCCCTTCATGGCTGCTGCCGCTCTGGATCCTCGCcgcgAGCCCGAGGAGGAGACACCCGATGAACCCAAGCTGATCATGGACATTGATGAGCCGGAGATCAAGGATCTAAGGGCCCCCACACCCGAAATCCGAGAGGAGGCAGCGGCTCCCATTAAACAAGAGCCCAGCAGGGAGGCCTCCCCAGTTCCCGAGAGTGATCCCGCTACGCCGCAGGAGATTAAGCAAGAACAGGTACAGGAACCGCTGTCGGTAGAAGAGGCGGAGCCACAGTCCTCGGTTGAAGAACCCTCCTCAATAGAGCCACTCGCCGATTTGCGCTGCAGTCGCTGCTCCAAGCAGTTCAACCACCCAACCGAGCTAGTGCAGCACGAGAAGGTGTTGTGTGGCCTTATCAAGGAGGAGCTAGAGCAACATTTccatcaacaacagcagcagcaactgcaactccaGACCACGTCCTTTGTGATGCCATCCGCCAGCGAAGAAgacgacgaggatgaggagatggaggaggagccgcGACAGGAGAGCGGTGAGCGCAAGGTCCGAGTGCGAACGGCCATcaacgaggagcagcagcagcagttaaAGCAGCATTACTCCCTGAACTCGCGACCCAGCCGAGATGAGTTCCGGATGATAGCCGCCCGCCTGCAGCTCGACCCGCGCGTGGTCCAAGTCTGGTTCCAGAACAATCGATCTCGCGAGCGAAAGATGCAGAGTTTCCAGAGTAACCAAACCACGCCCGTGGCCAACAATGAAGCTCAAACCTCGCAGACTTCACGTGAGGATCAACCCTTGGATCTGTCCATCAAGCGAGATCTGCTGACGCCAAAAAGCGAGAGCTCGCCACCCTACATACCGCCGCAGAGCACTGAGGCCCTGAATCCCGAGGCCGCCATCAATCTGAGCAGGAAGTTCTCCAGCTCCGCCTCGATGTCGCCAGCCTCGATTTCACCCTCATCCGCGGCGGCCATCTACTTTGGCGCTGGCCCGCCGCCTTCGCCGCCCAACAGCCAACTGGAGGCCACTCCTCGAACGGCCGGCCAGGCCTTTCCCGGACTGCCCTACATGCTGCCCATGCCCCGACTCCCCATGGAGGCCCTGTTCCAAATGCGTCCCGGTGGCGAGTATGCCCCCAATCATCCCCTGATGAACAGTATTAAGCTGCCCGATTATCGTGGCACAAGTCTGAGTCCCGGCGGTTCAGAGAAGCGGTCGTGGCGCGACGATGACTCGCGCATCTCCCACGAGGATGACTTCAGCGGCGGACTGCTGCCGCCGAAGCCGAGGCGAGGCAAGCAGGAGACCCATGGCCATGCCGGTGACCCCGATCTGCCCTTTGTGTGCGATCAGTGTGACAAGGCCTTCGCCAAGCAGAGCTCATTGGCGCGCCACAAGTACGAGCATTCCGGTCAAAGACCCTACCAGTGCATGGACTGCCCAAAGGCCTTCAAGCACAAGCACCACCTGACGGAGCACAAGCGTCTGCATAGCGGCGAGAAGCCCTTCCAATGCTCCAAGTGCCTGAAACGCTTCTCCCACTCGGGCAGCTACAGCCAGCACATGAACCACCGCTACTCCTACTGCAAGCCCTACAGGGAATAG
Protein Sequence: PSLASSLLHHNQSPKHSNPGNVVQDAQIAQPGPAADAFMVNCTQCHKRFIGFQSLTEHMASEHPHDKLNCGAAQPESDAEDEQSNLSGSSSRRYIKSPAQATGNTSNNSNNNNISVHPSSNSSNNNNNNSELTKNQNNNSTTPKMSPMCSPGSMPPSDLFAHLPHGTPQLQLQAHPGSTTGDRELGGAYPCMQCTAAFATREQLEQHQLLHSPCGQPAAQNVSQTCRICQKAFANVYRLQRHMISHDESALLRKFKCKECDKAFKFKHHLKEHVRIHSGEKPFGCDNCGKRFSHSGSFSSHMTSKKCISMGLKLNNNRALLKRLEKSPGSGGAARRSPSDQGLKQEQQSGLPGLPNPMIYFASDAQGQAGNTAATPFPPFHPTNYMNAALFSFPNPFMAAAALDPRREPEEETPDEPKLIMDIDEPEIKDLRAPTPEIREEAAAPIKQEPSREASPVPESDPATPQEIKQEQVQEPLSVEEAEPQSSVEEPSSIEPLADLRCSRCSKQFNHPTELVQHEKVLCGLIKEELEQHFHQQQQQQLQLQTTSFVMPSASEEDDEDEEMEEEPRQESGERKVRVRTAINEEQQQQLKQHYSLNSRPSRDEFRMIAARLQLDPRVVQVWFQNNRSRERKMQSFQSNQTTPVANNEAQTSQTSREDQPLDLSIKRDLLTPKSESSPPYIPPQSTEALNPEAAINLSRKFSSSASMSPASISPSSAAAIYFGAGPPPSPPNSQLEATPRTAGQAFPGLPYMLPMPRLPMEALFQMRPGGEYAPNHPLMNSIKLPDYRGTSLSPGGSEKRSWRDDDSRISHEDDFSGGLLPPKPRRGKQETHGHAGDPDLPFVCDQCDKAFAKQSSLARHKYEHSGQRPYQCMDCPKAFKHKHHLTEHKRLHSGEKPFQCSKCLKRFSHSGSYSQHMNHRYSYCKPYRE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00480071;
90% Identity: iTF_00488559;
80% Identity: iTF_00492121;